Specificity of binding of the plectin actin-binding domain to β4 integrin

Molecular Biology of the Cell

Volumn 14, Issue 10, 2003, Pages 4039-4050

  Litjens, Sandy H M ^a   Koster, Jan ^a   Kuikman, Ingrid ^a   Van Wilpe, Sandra ^a   De Pereda, José M ^b   Sonnenberg, Arnoud ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; BETA4 INTEGRIN; BINDING PROTEIN; BULLOUS PEMPHIGOID ANTIGEN 1; F ACTIN; PLECTIN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOSKELETON; HEMIDESMOSOME; INTERMEDIATE FILAMENT; KERATINOCYTE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; STEREOSPECIFICITY;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOSKELETAL PROTEINS; CYTOSKELETON; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTEGRIN BETA4; INTERMEDIATE FILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; PLECTIN; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 0141764796     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E03-05-0268     Document Type: Article

References (50)

1. Andrä, K., Kornacker, I., Jorgl, A., Zorer, M., Spazierer, D., Fuchs, P., Fischer, I., and Wiche, G. (2003). Plectin-isoform-specific rescue of hemidesmosomal defects in plectin (-/-) keratinocytes. J. Invest. Dermatol. 120, 189-197.
2. Andrä, K., Lassmann, H., Bittner, R., Shorny, S., Fässler, R., Propst, F., and Wiche, G. (1997). Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture. Genes Dev. 11, 3143-3156.
3. Bernier, G., De Repentigny, Y., Mathieu, M., David, S., and Kothary, R. (1998). Dystonin is an essential component of the Schwann cell cytoskeleton at the time of myelination. Development 125, 2135-2148.
4. Borradori, L., and Sonnenberg, A. (1996). Hemidesmosomes: roles in adhesion, signaling and human diseases. Curr. Opin. Cell Biol. 8, 647-656.
5. Bresnick, A.R., Janmey, P.A., and Condeelis, J. (1991). Evidence that a 27-residue sequence is the actin-binding site of ABP-120. J. Biol. Chem. 266, 12989-12993.
6. Bresnick, A.R., Warren, V., and Condeelis, J. (1990). Identification of a short sequence essential for actin binding by Dictyostelium ABP-120. J. Biol. Chem., 265, 9236-9240.
7. Brown, A., Dalpe, G., Mathieu, M., and Kothary, R. (1995). Cloning and characterization of the neural isoforms of human dystonin. Genomics 29, 777-780.
8. Burgeson, R.E., and Christiano, A.M. (1997). The dermal-epidermal junction. Curr. Opin. Cell Biol. 9, 651-658.
9. de Pereda, J.M., Wiche, G., and Liddington, R.C. (1999). Crystal structure of a tandem pair of fibronectin type III domains from the cytoplasmic tail of integrin α6β4. EMBO J. 18, 4087-4095.
10. Dowling, J., Yu, Q.C., and Fuchs, E. (1996). β4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J. Cell Biol. 134, 559-572.
11. Einheber, S., Milner, T.A., Giancotti, F., and Salzer, J.L. (1993). Axonal regulation of Schwann cell integrin expression suggests a role for α6/β4 in myelination. J. Cell Biol. 123, 1223-1236.
12. Feltri, M.L., Scherer, S.S., Nemni, R., Kamholz, J., Vogelbacker, H., Scott, M.O., Canal, N., Quaranta, V., and Wrabetz, L. (1994). β4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. Development 120, 1287-1301.
13. Foisner, R., and Wiche, G. (1987). Structure and hydrodynamic properties of plectin molecules. J. Mol. Biol. 198, 515-531.
14. Fontao, L., Geerts, D., Kuikman, I., Koster, J., Kramer, D., and Sonnenberg, A. (2001). The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectin. J. Cell Sci. 114, 2065-2076.
15. Fuchs, P., Zorer, M., Rezniczek, G.A., Spazierer, D., Oehler, S., Castanon, M.J., Hauptmann, R., and Wiche, G. (1999). Unusual 5′ transcript complexity of plectin isoforms: novel tissue-specific exons modulate actin binding activity. Hum. Mol. Genet. 8, 2461-2472.
16. Gache, Y., Chavanas, S., Lacour, J.P., Wiche, G., Owaribe, K., Meneguzzi, G., and Ortonne, J.P. (1996). Defective expression of plectin/HD1 in epidermolysis bullosa simplex with muscular dystrophy. J. Clin. Invest. 97, 2289-2298.
17. García-Alvarez, B., Bobkov, A., Sonnenberg, A., and de Pereda, J.M. (2003). Structural and functional analysis of the actin binding domain of plectin suggests alternative mechanisms for binding to F-actin and integrin α6β4. Structure 11, 615-625.
18. Geerts, D., Fontao, L., Nievers, M.G., Schaapveld, R.Q., Purkis, P.E., Wheeler, G.N., Lane, E.B., Leigh, I.M., and Sonnenberg, A. (1999). Binding of integrin α6β4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding. J. Cell Biol. 147, 417-434.
19. Georges-Labouesse, E., Messaddeq, N., Yehia, G., Cadalbert, L., Dierich, A., and Le Meur, M. (1996). Absence of integrin α6 leads to epidermolysis bullosa and neonatal death in mice. Nat. Genet. 13, 370-373.
20. Gimona, M., Djinovic-Carugo, K., Kranewitter, W.J., and Winder, S.J. (2002). Functional plasticity of CH domains. FEBS Lett. 513, 98-106.
21. Giudice, G.J., Emery, D.J., and Diaz, L.A. (1992). Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180. J. Invest. Dermatol. 99, 243-250.
22. Green, K.J., and Jones, J.C. (1996). Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J. 10, 871-881.
23. Hartwig, J.H. (1994). Actin-binding proteins 1, spectrin superfamily. Protein Profile 1, 706-778.
24. James, P., Halladay, J., and Craig, E.A. (1996). Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144, 1425-1436.
25. Jones, J.C., Kurpakus, M.A., Cooper, H.M., and Quaranta, V. (1991). A function for the integrin α6β4 in the hemidesmosome. Cell Regul. 2, 427-438.
26. Keep, N.H., Winder, S.J., Moores, C.A., Walke, S., Norwood, F.L., and Kendrick-Jones, J. (1999). Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer. Structure Fold. Des. 7, 1539-1546.
27. Koster, J., Kuikman, I., Kreft, M., and Sonnenberg, A. (2001). Two different mutations in the cytoplasmic domain of the integrin β4 subunit in nonlethal forms of epidermolysis bullosa prevent interaction of β4 with plectin. J. Invest. Dermatol. 117, 1405-1411.
28. Leung, C.L., Zheng, M., Prater, S.M., and Liem, R.K. (2001). The BPAG1 locus: Alternative splicing produces multiple isoforms with distinct cytoskeletal linker domains, including predominant isoforms in neurons and muscles. J. Cell Biol. 154, 691-697.
29. Levine, B.A., Moir, A.J., Patchell, V.B., and Perry, S.V. (1992). Binding sites involved in the interaction of actin with the N-terminal region of dystrophin. FEBS Lett. 298, 44-48.
30. Liu, C.G., Maercker, C., Castanon, M.J., Hauptmann, R., and Wiche, G. (1996). Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24). Proc. Natl. Acad. Sci. USA 93, 4278-4283.
31. McLean, W.H. et al. (1996). Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization. Genes Dev. 10, 1724-1735.
32. Merritt, E.A., and Bacon, D.J. (1997). Raster 3D: Photorealistic molecular graphics. In: Methods in Enzymology, Macomolecular Cryptallography, Part B. ed. C.W. Carter and R.M. Sweet, New York: Academic Press, 277, 505-524.
33. Nakano, A. et al. (2001). Epidermolysis bullosa with congenital pyloric atresia: novel mutations in the β4 integrin gene (ITGB4) and genotype/phenotype correlations. Pediatr. Res. 49, 618-626.
34. Niessen, C.M., Cremona, O., Daams, H., Ferraresi, S., Sonnenberg, A., and Marchisio, P.C. (1994). Expression of the integrin α6β4 in peripheral nerves: localization in Schwann and perineural cells and different variants of the β4 subunit. J. Cell Sci. 107, 543-552.
35. Nievers, M.G., Schaapveld, R.Q., Oomen, L.C., Fontao, L., Geerts, D., and Sonnenberg, A. (1998). Ligand-independent role of the β4 integrin subunit in the formation of hemidesmosomes. J. Cell Sci. 111, 1659-1672.
36. Norwood, F.L., Sutherland-Smith, A.J., Keep, N.H., and Kendrick-Jones, J. (2000). The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy. Structure Fold. Des. 8, 481-491.
37. Pulkkinen, L., Rouan, F., Bruckner-Tuderman, L., Wallerstein, R., Garzon, M., Brown, T., Smith, L., Carter, W., and Uitto, J. (1998). Novel ITGB4 mutations in lethal and nonlethal variants of epidermolysis bullosa with pyloric atresia: missense versus nonsense. Am. J. Hum. Genet. 63, 1376-1387.
38. Rezniczek, G.A., de Pereda, J.M., Reipert, S., and Wiche, G. (1998). Linking integrin α6β4-based cell adhesion to the intermediate filament cytoskeleton: direct interaction between the β4 subunit and plectin at multiple molecular sites. J. Cell Biol. 141, 209-225.
39. Ruzzi, L., Gagnoux-Palacios, L., Pinola, M., Belli, S., Meneguzzi, G., D'Alessio, M., and Zambruno, G. (1997). A homozygous mutation in the integrin α6 gene in junctional epidermolysis bullosa with pyloric atresia. J. Clin. Invest. 99, 2826-2831.
40. Schaapveld, R.Q. et al. (1998). Hemidesmosome formation is initiated by the β4 integrin subunit, requires complex formation of 4 and H.D1/plectin, and involves a direct interaction between β4 and the bullous pemphigoid antigen 180. J. Cell Biol. 142, 271-284.
41. Seed, B., and Aruffo, A. (1987). Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA 84, 3365-3369.
42. Smith, F.J. et al. (1996). Plectin deficiency results in muscular dystrophy with epidermolysis bullosa. Nat. Genet. 13, 450-457.
43. Sonnenberg, A. et al. (1991). Integrin α6β4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion. J. Cell Biol. 113, 907-917.
44. Sonnenberg, A., Linders, C.J., Daams, J.H., and Kennel, S.J. (1990). The α6β1 (VLA-6) and α6β4 protein complexes: tissue distribution and biochemical properties. J. Cell Sci. 96, 207-217.
45. Steinbock, F.A., and Wiche, G. (1999). Plectin: a cytolinker by design. Biol. Chem. 380, 151-158.
46. Stepp, M.A., Spurr-Michaud, S., Tisdale, A., Elwell, J., and Gipson, I.K. (1990). α6β4 integrin heterodimer is a component of hemidesmosomes. Proc. Natl. Acad. Sci. USA 87, 8970-8974.
47. Sterk, L.M., Geuijen, C.A., Oomen, L.C., Calafat, J., Janssen, H., and Sonnenberg, A. (2000). The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin α6β4 and may regulate the spatial organization of hemidesmosomes. J. Cell Biol. 149, 969-982.
48. van der Neut, R., Krimpenfort, P., Calafat, J., Niessen, C.M., and Sonnenberg, A. (1996). Epithelial detachment due to absence of hemidesmosomes in integrin β4 null mice. Nat. Genet. 13, 366-369.
49. Vidal, F., Aberdam, D., Miquel, C., Christiano, A.M., Pulkkinen, L., Uitto, J., Ortonne, J.P., and Meneguzzi, G. (1995). Integrin β4 mutations associated with junctional epidermolysis bullosa with pyloric atresia. Nat. Genet. 10, 229-234.
50. Wiche, G. (1998). Role of plectin in cytoskeleton organization and dynamics. J. Cell Sci. 111, 2477-2486.