Lack of cyclic nucleotide regulation of MBCQ-induced relaxation of rat ileal smooth muscle

Journal of Smooth Muscle Research

Volumn 39, Issue 3, 2003, Pages 47-54

  Kaneda, Takeharu ^a   Yamamoto, Hideyuki ^a   Azegami, Yoshihiro ^a   Shimizu, Kazumasa ^a   Urakawa, Norimoto ^a   Nakajyo, Shinjiro ^a  

^a NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY   (Japan)

Author keywords

Cyclic AMP; Cyclic GMP; MBCQ; Phosphodiesterase inhibitor; Rat ileum

Indexed keywords

4 [[3,4 (METHYLENEDIOXY)BENZYL]AMINO] 6 CHLOROQUINAZOLINE; CYCLIC GMP; CYCLIC NUCLEOTIDE; DIPYRIDAMOLE; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHLORIDE; POTASSIUM ION; UNCLASSIFIED DRUG; ZAPRINAST;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; DRUG POTENCY; ENZYME INHIBITION; IC 50; ILEUM; INTESTINE CONTRACTION; INTESTINE MUSCLE; MALE; NONHUMAN; PROTEIN CONTENT; RAT; SMOOTH MUSCLE RELAXATION;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; CARBACHOL; CHOLINERGIC AGONISTS; CYCLIC AMP; CYCLIC GMP; DIPYRIDAMOLE; ILEUM; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; POTASSIUM; PURINONES; QUINAZOLINES; RATS; RATS, WISTAR;

EID: 0141756269     PISSN: 09168737     EISSN: None     Source Type: Journal    
DOI: 10.1540/jsmr.39.47     Document Type: Article

References (26)

1. Ahn, H.S., Crim, W, Romano, M., Sybertz, E. and Pitts, B. (1989). Effects of selective inhibitors of cyclic nucleotide phosphodiesterases of rabbit aorta. Biochem. Pharmacol. 38: 3331-3339.
2. Appleman, M.M. and Terasaki, W.L. (1975). Regulation of cyclic nucleotide phosphodiesterases. Cyclic Nucleotide Res. 5: 153-162.
3. Barnette, M.S., Manning, C.D., Price, W.J. and Barone, F.C. (1993). Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle. J. Pharmacol. Exp. Ther. 264: 801-812.
4. Beavo, J.A. (1995). Cyclic nucleotide phosphodiesterase: functional implications of multiple isoforms. Physiol. Rev. 75: 725-748.
5. Beavo, J.A. and Reifsnyder, D.H. (1990). Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trend. Pharmacol. Sci. 11: 150-155.
6. Burns, F., Stevens, P.A. and Pyne, N.J. (1994). The identification of apparently novel cyclic AMP and cyclic GMP phosphodiestrease activities in guinea-pig tracheal smooth muscle. Br. J. Pharmacol. 113: 3-4.
7. Diamond, J. (1978). Role of cyclic nucleotides in control of smooth muscle contraction. In: Advances in Cyclic Nucleotide Research vol.9, ed. by W.J. George and L.J. Ignarro, Raven Press, New York, pp. 327-340.
8. Fawcett, L., Baxendale, R., Stacey, P., Mcgrother, C., Harrow, I., Soderling, S.H. and Beavo, J.A. (2000). Molecular cloning and characterization of distinct human phosphodiesterase gene family: PDE11A. Proc. Nalt. Acard. Sci. USA. 97: 3702-3707.
9. Harris, A.L., Lemp, B.M., Bentley, R.G., Perrone, M.H., Hamel, L.T. and Silver, P.J. (1989). Phosphodiesterase isozyme inhibition and the potentiation by zaprinast of endothelium-derived relaxing factor and guanylate cyclase stimulating agents in vascular smooth muscle. J. Pharmacol. Exp. Ther. 249: 394-400.
10. Ivorra, M.D., Le Bec, A. and Lugnier, C. (1992). Characterization of membrane-bound cyclic nucleotide phosphodiesterases from bovine aortic smooth muscle. J. Cardiovasc. Pharmacol. 19: 532-540.
11. Kaneda, T., Shimizu, K., Nakajyo, S. and Urakawa, N. (1998). The difference in the inhibitory mechanisms of papaverine on vascular and intestinal smooth muscles. Eur. J. Pharmacol. 355: 149-157.
12. Karaki, H., Sato, K., Ozaki, H. and Murakami, K. (1988). Effects of sodium nitroprusside on cytosolic calcium level in vascular smooth muscle. Eur. J. Pharmacol. 156: 259-266.
13. Komas, N., Lugnier, C., Andriantsitohaina, R. and Stoclet, J-C. (1991a). Characterization of cyclic nucleotide phosphodiesterases from rat mesenteric artery. Eur. J. Pharmacol. 208: 85-87.
14. Komas, N., Lugnier, C. and Stoclet, J.-C. (1991b). Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors. Br. J. Pharmacol 104: 495-503.
15. 2+ and contraction in guinea pig taenia caecum. Jpn. J. Pharmacol. 61: 57-64.
16. Paton, W.D.M. and Aboo Zar, M. (1968). The origin of acetylcholine released from guinea pig intestine and longitudinal muscle strips. J. Physiol. (Lond.) 194: 13-33.
17. Polson, J.B. and Strada, S.J. (1996). Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Annu. Rev. Phramacol. Toxicol. 36: 403-427.
18. Qiu, Y., Kraft, P., Craig, E.C., Liu, X. and Haynes-Johnson, D. (2001). Identification and functional study of phosphodiesterases in rat urinary bladder. Urol. Res. 29: 388-392.
19. Raeburn, D. and Advenier, C. (1995). Isoenzyme-selective cyclic nucleotide phosphodiesterase inhibitors: Effects on airways smooth muscle. Int J. Biochem. Cell Biol. 27: 29-37.
20. Rybalkin, S.D., Rybalkina, I.G., Feil, R., Hofmann, F. and Beavo, J.A. (2002). Regulation of cGMP-specific phosphodiesterase (PDE5) phosphorylation in smooth muscle cells. J. Biol. Chem. 277: 3310-3317.
21. Sampson, L.J., Hinton, J.M. and Garland, C.J. (2001). Evidence for expression and function of phosphodiesterase type 5 (PDE-V) in rat resistance arteries. Br. J. Pharmacol. 132: 13-17.
22. Tajimi, M., Hori, M., Mitsui, M., Ozaki, H. and Karaki, H. (1995). Inhibitory effects of forskolin on myosin phosphorylation-dependent and independent contraction in bovine tracheal smooth muscle. J. Smooth Muscle Res. 31: 129-142.
23. Takase, Y., Saeki, T., Watanabe, N., Adachi, H., Souda, S. and Saito, I. (1994). Cyclic GMP phosphodiesterase inhibitor. 2. Requirement of 6-substitution of quinazoline derivatives for potent and selective inhibitory activity. J. Med. Chem. 37: 2106-2111.
24. Tomkinson, A. and Raeburn, D. (1996). The effect of isoenzyme-selective PDE inhibitors on methacholine-induced contraction of guinea-pig and rat ileum. Br. J. Pharmacol. 118: 2131-2139.
25. Yuasa, K., Kotera, J., Fujishige, K., Michibata, H., Sasaki, T. and Omori, K. (2000). Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression. J. Biol. Chem. 275: 31469-31479.
26. Van Der Zypp, A., Rechtman, M. and Majewski, H. (2000). The role of cyclic nucleotide and calcium in the relaxation produced by amurinone in rat aorta. Gen. Phramacol. 34: 245-253.