Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells

Journal of Clinical Investigation

Volumn 112, Issue 5, 2003, Pages 745-754

  Colgan, Sean P ^a   Pitman, Richard S ^a   Nagaishi, Takashi ^a   Mizoguchi, Atsushi ^b   Mizoguchi, Emiko ^b   Mayer, Lloyd F ^c   Shao, Ling ^c   Sartor, R Balfour ^d   Subjeck, John R ^e   Blumberg, Richard S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; HEAT SHOCK PROTEIN 110; CD1 ANTIGEN; HEAT SHOCK PROTEIN 70; HSPH1 PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CONFOCAL MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; INTESTINE EPITHELIUM CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; AMINO ACID SEQUENCE; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; MOLECULAR GENETICS; PHYSIOLOGY;

AMINO ACID SEQUENCE; ANTIGENS, CD1; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HSP110 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTESTINAL MUCOSA; MOLECULAR SEQUENCE DATA;

EID: 0141723663     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200317241     Document Type: Article

References (36)

1. Blumberg, R.S., Gerdes, D., Chott, A., Porcelli, S.A., and Balk, S.P. 1995. Structure and function of the CD1 family of MHC-like cell surface proteins. Immunol. Rev. 147:5-29.
2. Briken, V., Moody, D.B., and Porcelli, S.A. 2000. Diversification of CD1 proteins: sampling the lipid content of different cellular compartments. Semin. Immunol. 12:517-525.
3. Exley, M., et al. 2000. CD1d structure and regulation on human thymocytes, peripheral blood T cells, B cells and monocytes. Immunology. 100:37-47.
4. Canchis, P.W., et al. 1993. Tissue distribution of the non-polymorphic major histocompatibility complex class I-like molecule, CD1d. Immunology. 80:561-565.
5. Blumberg, R.S., et al. 1991. Expression of a nonpolymorphic MHC class I-like molecule, CD1d, by a human intestinal epithelial cells. J. Immunol. 147:2518-2524.
6. Saubermann, L.J., et al. 2000. Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. Gastroenterology. 119:119-128.
7. Heller, F., Fuss, I.J., Nieuwenhuis, E.E., Blumberg, R.S., and Strober, W. 2002. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity. 17:629-638.
8. Colgan, S.P., Hershberg, R.M., Furuta, G.T., and Blumberg, R.S. 1999. Ligation of intestinal epithelial CD1d induces bioactive IL-10: critical role of the cytoplasmic tail in autocrine signaling. Proc. Natl. Acad. Sci. U. S. A. 96:13938-13943.
9. Somnay-Wadgaonkar, K., et al. 1999. Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form. Int. Immunol. 11:383-392.
10. Colgan, S.P., Morales, V.M., Madara, J.L., Balk, S.P., and Blumberg, R.S. 1996. IFN-γ modulates CD1d expression on intestinal epithelia. Am. J. Physiol. 271:C276-C283.
11. Kim, H.S., et al. 1999. Biochemical characterization of CD1d expression in the absence of beta2-microglobulin. J. Biol. Chem. 274:9289-9295.
12. Exley, M., Porcelli, S., Furman, M., Garcia, J., and Balk, S. 1998. CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant V alpha 24 J alpha Q T cell receptor alpha chains. J. Exp. Med. 188:867-876.
13. Wang, X.Y., et al. 2000. Characterization of native interaction of hsp110 with hsp25 and hsc70. FEBS Lett. 465:98-102.
14. Collard, C.D., et al. 2002. Neutrophil-derived glutamate regulates vascular endothelial barrier function. J. Biol. Chem. 2002:14801-14811.
15. Lee-Yoon, D., Easton, D., Murawski, M., Burd, R., and Subjeck, J.R. 1995. Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein. J. Biol. Chem. 270:15725-15733.
16. Parkos, C.A., et al. 1996. CD 47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia. J. Cell Biol. 132:437-450.
17. Schultz, M., et al. 1999. IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation. Am. J. Physiol. 276:G1461-G1472.
18. Colgan, S.P., et al. 1994. Interferon-γ induces a surface phenotype switch in intestinal epithelia: downregulation of ion transport and upregulation of immune accessory ligands. Am. J. Physiol. 267:C402-C410.
19. Parkos, C.A., et al. 1996. Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11b/18-mediated interactions with neutrophils. Mol. Med. 2:489-505.
20. Mizoguchi, E., Mizoguchi, A., and Bhan, A.K. 1997. Role of cytokines in the early stages of chronic colitis in TCR alpha-mutant mice. Lab. Invest. 76:385-397.
21. Panja, A., Blumberg, R.S., Balk, S.P., and Mayer, L. 1993. CD1d is involved in T cell-intestinal epithelial cell interactions. J. Exp. Med. 178:1115-1119.
22. Pitman, R.S., and Blumberg, R.S. 2000. First line of defense: the role of the intestinal epithelium as an active component of the mucosal immune system. J. Gastroenterol. 35:805-814.
23. 2-Microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium. Science. 265:259-262.
24. Canny, G., et al. 2002. Lipid mediator-induced expression of bactericidal/permeability-increasing protein (BPI) in human mucosal epithelia. Proc. Natl. Acad. Sci. U. S. A. 99:3902-3907.
25. Li, Z., Menoret, A., and Srivastava, P. 2002. Roles of heat-shock proteins in antigen presentation and cross-presentation. Curr. Opin. Immunol. 14:45-51.
26. Ohashi, K., Burkart, V., Flohe, S., and Kolb, H. 2000. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 164:558-561.
27. Asea, A., et al. 2002. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 277:15028-15034.
28. Asea, A., et al. 2000. HSP70 stimulates cytokine production through a CD14-dependent pathway, demonstrating its dual role as a chaperone and cytokine. Nat. Med. 6:435-442.
29. Cario, E., et al. 2000. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J. Immunol. 164:966-972.
30. Gewittz, A.T., Navas, T.A., Lyons, S., Godowski, P.J., and Madara, J.L. 2001. Cutting edge: bacterial flagellin activates basolaterally expressed tlr5 to induce epithelial proinflammatory gene expression. J. Immunol. 167:1882-1885.
31. Pugin, J., et al. 1993. Lipolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysacchride-binding protein and soluble CD14. Proc. Natl. Acad. Sci. U. S. A. 90:2744-2748.
32. Becker, T., Hartl, F.U., and Wieland, F. 2002. CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. J. Cell Biol. 158:1277-1285.
33. Binder, R.J., Han, D.K., and Srivastava, P.K. 2000. CD91: a receptor for heat shock protein gp96. Nat. Immunol. 1:151-155.
34. Basu, S., Binder, R.J., Ramalingam, T., and Srivastava, P.K. 2001. CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity. 14:303-313.
35. Nagler-Anderson, C. 2001. Man the barrier! Strategic defences in the intestinal mucosa. Nat. Rev. Immunol. 1:59-67.
36. Bobryshev, Y.V., and Lord, R.S. 2002. Expression of heat shock protein-70 by dendritic cells in the arterial intima and its potential significance in atherogenesis. J. Vasc. Surg. 35:368-375.