Identification of an alternatively processed nicotinic receptor α7 subunit RNA in mouse brain

Molecular Brain Research

Volumn 117, Issue 1, 2003, Pages 15-26

  Saragoza, Philip A ^a   Modir, James G ^b   Goel, Nidhi ^a   French, Kristen L ^c   Li, Li ^c   Nowak, Mark W ^c   Stitzel, Jerry A ^a,d  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Alternative splicing; Dominant negative; RNA editing

Indexed keywords

MEMBRANE PROTEIN; NICOTINIC RECEPTOR; PROTEIN SUBUNIT; RECOMBINANT RNA;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MOUSE; NEUROMODULATION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN VARIANT; TISSUE DISTRIBUTION;

EID: 0141671837     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(03)00261-4     Document Type: Article

References (61)

1. Adams C.E., Broide R.S., Chen Y., Winzer-Serhan U.H., Henderson T.A., Leslie F.M., Freedman R. Development of the alpha7 nicotinic cholinergic receptor in rat hippocampal formation. Dev. Brain Res. 139:2002;175-187.
2. Alkondon M., Pereira E.F., Albuquerque E.X. Alpha-bungarotoxin- and methyllycaconitine-sensitive nicotinic receptors mediate fast synaptic transmission in interneurons of rat hippocampal slices. Brain Res. 810:1998;257-633.
3. Berger F., Gage F.H., Vijayaraghavan S. Nicotinic receptor-induced apoptotic cell death of hippocampal progenitor cells. J. Neurosci. 18:1998;6871-6881.
4. Bourara K., Litvak S., Araya A. Generation of G-to-A and C-to-U changes in HIV-1 transcripts by RNA editing. Science. 289:2000;1564-1566.
5. Broide R.S., O'Connor L.T., Smith M.A., Smith J.A., Leslie F.M. Developmental expression of alpha 7 neuronal nicotinic receptor messenger RNA in rat sensory cortex and thalamus. Neuroscience. 67:1995;83-94.
6. Broide R.S., Salas R., Ji D., Paylor R., Patrick J.W., Dani J.A., De Biasi M. Increased sensitivity to nicotine-induced seizures in mice expressing the L250T α7 nicotinic acetylcholine receptor mutation. Mol. Pharmacol. 61:2002;695-705.
7. Bullock A.E., Slobe B.S., Vazquez V., Collins A.C. Inbred mouse strains differ in the regulation of startle and prepulse inhibition of the startle response. Behav. Neurosci. 111:1997;1353-1360.
8. Chan J., Quik M.A. Role for the nicotinic alpha-bungarotoxin receptor in neurite outgrowth in PC12 cells. Neuroscience. 56:1993;441-451.
9. Chang K.T., Berg D.K. Nicotinic acetylcholine receptors containing alpha7 subunits are required for reliable synaptic transmission in situ. J. Neurosci. 19:1999;3701-3710.
10. Chen D., Patrick J.W. The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit. J. Biol. Chem. 272:1997;24024-24029.
11. Chen D., Dang H., Patrick J.W. Contributions of N-linked glycosylation to the expression of a functional α7-nicotinic receptor in Xenopus oocytes. J. Neurochem. 70:1998;349-357.
12. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
13. Coronas V., Durand M., Chabot J.G., Jourdan F., Quirion R. Acetylcholine induces neuritic outgrowth in rat primary olfactory bulb cultures. Neuroscience. 98:2000;213-219.
14. Corriveau R.A., Berg D.K. Coexpression of multiple acetylcholine receptor genes in neurons: quantification of transcripts during development. J. Neurosci. 13:1993;2662-2711.
15. Couturier S., Bertrand D., Matter J.M., Hernandez M.C., Bertrand S., Millar N., Valera S., Barkas T., Ballivet M.A. Neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron. 5:1990;847-856.
16. Cuevas J., Berg D.K. Mammalian nicotinic receptors with alpha7 subunits that slowly desensitize and rapidly recover from alpha-bungarotoxin blockade. J. Neurosci. 18:1998;10335-10344.
17. Cuevas J., Roth A.L., Berg D.K. Two distinct classes of functional 7-containing nicotinic receptor on rat superior cervical ganglion neurons. J. Physiol. 525:2000;735-746.
18. Damaj M.I., Glassco W., Dukat M., Martin B.R. Pharmacological characterization of nicotine-induced seizures in mice. J. Pharmacol. Exp. Ther. 291:1999;1284-1291.
19. Drisdel R.C., Green W.N. Neuronal alpha-bungarotoxin receptors are alpha7 subunit homomers. J. Neurosci. 20:2000;133-139.
20. Dubchak I., Brudno M., Loots G.G., Mayor C., Pachter L., Rubin E.M., Frazer K.A. Active conservation of noncoding sequences revealed by 3-way species comparisons. Genome Res. 10:2000;1304-1306.
21. Erkman L., Matter J., Matter-Sadzinski L., Ballivet M. Nicotinic acetylcholine receptor gene expression in developing chick autonomic ganglia. Eur. J. Pharmacol. 393:2000;97-104.
22. Fabian-Fine R., Skehel P., Errington M.L., Davies H.A., Sher E., Stewart M.G., Fine A. Ultrastructural distribution of the alpha7 nicotinic acetylcholine receptor subunit in rat hippocampus. J. Neurosci. 21:2001;7993-8003.
23. Felix R., Levin E.D. Nicotinic antagonist administration into the ventral hippocampus and spatial working memory in rats. Neuroscience. 81:1997;1009-1177.
24. Frazier C.J., Buhler A.V., Weiner J.L., Dunwiddie T.V. Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. J. Neurosci. 18:1998;8228-8355.
25. Fu Y., Matta S.G., Gao W., Sharp B.M. Local alpha-bungarotoxin-sensitive nicotinic receptors in the nucleus accumbens modulate nicotine-stimulated dopamine secretion in vivo. Neuroscience. 101:2000;369-375.
26. Garcia-Guzman M., Sala F., Sala S., Campos-Caro A., Stuhmer W., Gutierrez L.M., Criado M. Alpha-bungarotoxin-sensitive nicotinic receptors on bovine chromaffin cells: molecular cloning, functional expression and alternative splicing of the alpha 7 subunit. Eur. J. Neurosci. 7:1995;647-655.
27. Gault J., Robinson M., Berger R., Drebing C., Logel J., Hopkins J., Moore T., Jacobs S., Meriwether J., Choi M.J., Kim E.J., Walton K., Buiting K., Davis A., Breese C., Freedman R., Leonard S. Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics. 52:1998;173-855.
28. Genzen J.R., Van Cleve W., McGehee D.S. Dorsal root ganglion neurons express multiple nicotinic acetylcholine receptor subtypes. J. Neurophysiol. 86:2001;1773-1782.
29. Goldman D., Deneris E., Luyten W., Kochhar A., Patrick J., Heinemann S. Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system. Cell. 48:1987;965-973.
30. Gotti C., Hanke W., Schlue W.R., Briscini L., Moretti M., Clementi F. A functional alpha-bungarotoxin receptor is present in chick cerebellum: purification and characterization. Neuroscience. 50:1992;117-127.
31. Gotti C., Moretti M., Longhi R., Briscini L., Balestra B., Clementi F. Expression of alpha-bungarotoxin receptor subtypes in chick central nervous system during development. J. Recept. Res. 14:1994;335-346.
32. Gotti C., Moretti M., Maggi R., Longhi R., Hanke W., Klinke N., Clementi F. Alpha7 and alpha8 nicotinic receptor subtypes immunopurified from chick retina have different immunological, pharmacological and functional properties. Eur. J. Neurosci. 9:1997;1201-1211.
33. Grabowski P.J., Black D.L. Alternative RNA splicing in the nervous system. Prog. Neurobiol. 65:2001;289-308.
34. Hamill O., Marty A., Neher E., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391:1981;85-100.
35. Ji D., Dani J.A. Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons. J. Neurophysiol. 83:2000;2682-2900.
36. Jones S., Yakel J.L. Functional nicotinic ACh receptors on interneurones in the rat hippocampus. J. Physiol. 504:1997;603-610.
37. 3H]dopamine release in rat striatal slices via glutamate release. Mol. Pharmacol. 58:2000;312-318.
38. Kaneko S., Maeda T., Kume T., Kochiyama H., Akaike A., Shimohama S., Kimura J. Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors. Brain Res. 765:1997;135-140.
39. Levin E.D., Bettegowda C., Blosser J., Gordon J. AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats. Behav. Pharmacol. 10:1999;675-680.
40. Mansvelder H.D., McGehee D.S. Long-term potentiation of excitatory inputs to brain reward areas by nicotine. Neuron. 27:2000;349-577.
41. Marks M.J., Pauly J.R., Gross S.D., Deneris E.S., Hermans-Borgmeyer I., Heinemann S.F., Collins A.C. Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment. J. Neurosci. 12:1992;2765-2784.
42. Mayor C., Brudno M., Schwartz J.R., Poliakov A., Rubin E.M., Frazer K.A., Pachter L.S., Dubchak I. VISTA: visualizing global DNA sequence alignments of arbitrary length. Bioinformatics. 16:2000;1046-1047.
43. McGehee D.S., Heath M.J., Gelber S., Devay P., Role L.W. Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science. 269:1995;1692-1696.
44. Meyer E.M., Tay E.T., Papke R.L., Meyers C., Huang G.L., de Fiebre C.M. 3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner. Brain Res. 768:1997;49-56.
45. Miner L.L., Marks M.J., Collins A.C. Genetic analysis of nicotine-induced seizures and hippocampal nicotinic receptors in the mouse. J. Pharmacol. Exp. Ther. 239:1985;853-860.
46. O'Hara B.F., Macdonald E., Clegg D., Wiler S.W., Andretic R., Cao V.H., Miller J.D., Heller H.C., Kilduff T.S. Developmental changes in nicotinic receptor MRNAs and responses to nicotine in the suprachiasmatic nucleus and other brain regions. Mol. Brain Res. 66:1999;71-82.
47. Pugh P.C., Berg D.K. Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner. J. Neurosci. 14:1994;889-896.
48. Pugh P.C., Corriveau R.A., Conroy W.G., Berg D.K. Novel subpopulation of neuronal acetylcholine receptors among those binding alpha-bungarotoxin. Mol. Pharmacol. 47:1995;717-725.
49. Pugh P.C., Margiotta J.F. Nicotinic acetylcholine receptor agonists promote survival and reduce apoptosis of chick ciliary ganglion neurons. Mol. Cell. Neurosci. 15:2000;113-122.
50. Quik M., Choremis J., Komourian J., Lukas R.J., Puchacz E. Similiarity between rat brain nicotinic α-bungarotoxin receptors and stably expressed α-bungarotoxin binding sites. J. Neurochem. 67:1996;145-154.
51. Radcliffe K.A., Dani J.A. Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission. J. Neurosci. 18:1998;7075-7083.
52. Role L.W., Berg D.K. Nicotinic receptors in the development and modulation of CNS synapses. Neuron. 16:1996;1077-1085.
53. Schoepfer R., Conroy W.G., Whiting P., Gore M., Lindstrom J. Brain alpha-bungarotoxin binding protein CDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily. Neuron. 5:1990;35-48.
54. Seguela P., Wadiche J., Dineley-Miller K., Dani J.A., Patrick J.W. Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium. J. Neurosci. 13:1993;596-604.
55. Sharp P.A., Burge C.B. Classification of introns: U2-type or U12-type. Cell. 91:1997;875-879.
56. Shoop R.D., Martone M.E., Yamada N., Ellisman M.H., Berg D.K. Neuronal acetylcholine receptors with alpha7 subunits are concentrated on somatic spines for synaptic signaling in embryonic chick ciliary ganglia. J. Neurosci. 19:1999;692-704.
57. Stevens K.E., Freedman R., Collins A.C., Hall M., Leonard S., Marks M.J., Rose G.M. Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology. 15:1996;152-162.
58. Stevens K.E., Kem W R., Mahnir V.M., Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl.). 136:1998;320-327.
59. Stitzel J.A., Blanchette J.M., Collins A.C. Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes. J. Pharmacol. Exp. Ther. 284:1998;1104-1111.
60. Tohgi H., Utsugisawa K., Nagane Y. Protective effect of nicotine through nicotinic acetylcholine receptor alpha 7 on hypoxia-induced membrane disintegration and DNA fragmentation of cultured PC12 cells. Neurosci. Lett. 285:2000;91-94.
61. Yu C.R., Role L.W. Functional contribution of the alpha7 subunit to multiple subtypes of nicotinic receptors in embryonic chick sympathetic neurones. J. Physiol. 509:1998;651-665.