Brief report: Melatonin facilitates sleep in individuals with mental retardation and insomnia

Journal of Autism and Developmental Disorders

Volumn 33, Issue 4, 2003, Pages 469-472

  Niederhofer, H ^a   Staffen, W ^a   Mair, A ^a   Pittschieler, Klaus ^a  

^a Christian Doppler Klinik   (Austria)

Author keywords

Autism; Children; Melatonin; Psychopharmacological treatment; Sleep

Indexed keywords

MELATONIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD LEVEL; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFECT; FEMALE; HUMAN; INSOMNIA; MALE; MENTAL DEFICIENCY; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP;

ADMINISTRATION, ORAL; ADOLESCENT; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MELATONIN; MENTAL RETARDATION; POLYSOMNOGRAPHY; SLEEP INITIATION AND MAINTENANCE DISORDERS; WAKEFULNESS;

EID: 0141650620     PISSN: 01623257     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025027231938     Document Type: Article

References (22)

1. Dollins, A. B., Zhdanova, N., Wurtman, R. J., Lynch, H. J., & Deng, M. H. (1994). Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proceedings National Academy of Science of the USA, 91, 1824-1828.
2. Haimov, I., Laudon, M., & Zisapel, N. (1994). Sleep disorders and melatonin rhythms in elderly people. British Medical Journal, 309, 167-168.
3. Hajak, G., Rodenbeck, A., Staedt, J., Bandelow, E., Huether, G., & Ruther, E. (1995). Nortumal plasma melatonin levels in patients suffering from chronic primary insomnia. Journal of Pineal Research, 19, 116-122.
4. Hammond, E. (1964). Some preliminary findings on physical complaints from a prospective study of 1,064,004 men and women. American Journal of Public Health, 54, 11-15.
5. Heuvel, C. J., Kennaway, D. J., & Dawaan, D. (1999). Thermoregulatory and soporific effects of very low dose melatonin injection. American Journal of Physiology, 276, E249-E254.
6. Iguchi, H., Kato, K. I., & Ibayaahi, H. (1982). Age-dependent reduction in serum melatonin concentrations in healthy human subjects. Journal of Clinical Endocrinology and Metabolism, 55, 27-29.
7. Karacan, I., Thornby, J., Anch, M., et al. (1976). Prevalence of sleep disturbances in a primarily urban Florida county. Social Science and Medicine, 10, 239-247.
8. Kripke, D., Simons, R., Garfinkel, L., & Hammand, C. (1979). Short and long sleep and sleeping pills. Archives of General Psychiatry, 36, 103-108.
9. Lushington, K., Dawson, D., Kennaway, D. J., & Lack, L. (1999). The relationship between 6-sulphatoxymelatonin and polysomnographic sleep in good sleeping controls and wake maintenance insomniacs, aged 55-80 years. Journal of Sleep Research, 8(1), 57-64.
10. Lynch, H. J., Wurtman, R. J., Moskowitz, M. A., Archer, M. C., & Ho, M. H. (1975). Daily rhythm in human urinary melatonin. Science, 187, 169-171.
11. Sack, R. L., Lewy, A. J., Erb, D. L., Volimer, W. M., & Singer, C. M. (1986). Human melatonin production decreases with age. Journal of Pineal Research, 3, 379-388.
12. Sharma, M., Palacios-Bois, J., & Schwartz, G. (1989). Circadian rhythms of melatonin and cortisol in aging. Biological Psychiatry, 25, 305-319.
13. Stone, B. M., Turner, C., Mill, S. L., & Nicholson, A. N. (2000). Hypnotic activity of melatonin. Sleep, 23, 663-669.
14. Touitou, Y. (1982). Some aspects of the circadian time structure in the elderly. Gerontology, 28 (Suppl 1), 53-67.
15. Van Cauter, E., Plat, L., Lepronit, R., & Copinschi, G. (1998). Alterations of circadian rhythmicity and sleep in aging: endocrine consequences. Hormone Research, 49, 147-152.
16. Wurtman, R. J., & Zhdanova, I. V. (1995). Improvement of sleep quality by melatonin. Lancet, 346, 1491-1492.
17. Wyatt, J. K., Dijk, D. J., Ritz, D., Cecco, A., & Czeisler, C. A. (1999). Circadian phase-dependent hypnotic effect of exogenous melatonin. Sleep, 22, 54-55.
18. Zeitrer, J. M., Daniel, J. E., & Duffy, J. F. (1999). Do plasma melatonin concentrations decline with age? American Journal of Medicine, 107, 432-436.
19. Zhdanova, I. V., Wurtman, R. J., & Lynch, H. J. (1995). Sleep-inducing effects of low doses of melatonin ingested in the evening. Clinical Pharmacological Therapy, 57, 552-558.
20. Zhdanova, I. V., Wurtman, R. J., Morabito, C., Piotrovska, V., & Lynch, H. J. (1996). Effects of low doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans. Sleep, 19, 423-431.
21. Zhdanova, I. V., Wurtman, R. J., Balcioglu, A., Kartashov, A., & Lynch, H. J. (1998). Endogenous melatonin levels and the fate of exogenous melatonin: age effects. Journal of Gerontology, 53A, B293-B298.
22. Zhdanova, I. V., Lynch, H. J., & Wurtman, R. J. (1997). Melatonin: a sleep promoting hormone. Sleep, 20, 899-907.