In vivo and in vitro evidence that the four essential intermediate filament (IF) proteins A1, A2, A3 and B1 of the nematode Caenorhabditis elegans form an obligate heteropolymeric IF system

Journal of Molecular Biology

Volumn 333, Issue 2, 2003, Pages 307-319

  Karabinos, Anton ^a   Schulze, Ekkehard ^b   Schünemann, Jürgen ^a   Parry, David A D ^c   Weber, Klaus ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

C. elegans; Heteropolymers; Intermediate filament; Paralysis; RNA interference

Indexed keywords

GREEN FLUORESCENT PROTEIN; INTERMEDIATE FILAMENT PROTEIN; INTERMEDIATE FILAMENT PROTEIN A1; INTERMEDIATE FILAMENT PROTEIN A2; INTERMEDIATE FILAMENT PROTEIN A3; INTERMEDIATE FILAMENT PROTEIN A4; INTERMEDIATE FILAMENT PROTEIN B1; POLYMER; RECOMBINANT PROTEIN; RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLEACHING; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBRYO DEVELOPMENT; EXOCRINE GLAND; GENETIC VARIABILITY; IN VITRO STUDY; IN VIVO STUDY; INTERMEDIATE FILAMENT; INTESTINE; MOLECULAR PROBE; NEMATODE; NONHUMAN; PHARYNX; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; RECTUM; REPORTER GENE; SUBCUTANEOUS TISSUE; TISSUE DISTRIBUTION; TISSUE SPECIFICITY; TONOFILAMENT; UTERUS; VULVA;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; HYPODERRIS;

EID: 0141645631     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.08.041     Document Type: Article

References (32)

1. Hesse M., Magin T.M., Weber K. Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18. J. Cell Sci. 4:2001;2569-2575.
2. Fuchs E., Weber K. Intermediate filaments: structure, dynamics, function and disease. Annu. Rev. Biochem. 63:1994;345-382.
3. Parry D.A.D., Steinert P.M. Intermediate Filament Structure. 1995;Springer, New York.
4. Herrmann H., Hesse M., Reichenzeller M., Aebi U., Magin T.M. Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation. Int. Rev. Cytol. 83:2003;83-175.
5. Irvine A.D., McLean W.H. Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br. J. Dermatol. 140:1999;815-828.
6. Goldfarb L.G., Park K.Y., Cervenakova L., Gorokhova S., Lee H.S., Vasconcelos O., et al. Missense mutations in desmin associated with familial cardiac and skeletal myopathy. Nature Genet. 19:1998;402-403.
7. Brenner M., Johnson A.B., Boespflug-Tanguy O., Rodriguez D., Goldman J.E., Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nature Genet. 27:2001;117-120.
8. Goldman R.D. Worms reveal essential functions for intermediate filaments. Proc. Natl Acad. Sci. USA. 98:2001;7659-7661.
9. Karabinos A., Schünemann J., Parry D.A.D., Weber K. Tissue-specific coexpression and in vitro heteropolymer formation of the two small Branchiostoma intermediate filament proteins A3 and B2. J. Mol. Biol. 316:2002;127-137.
10. Wang J., Karabinos A., Schünemann J., Riemer D., Weber K. The epidermal intermediate filament proteins of tunicates are distant keratins; a polymerisation-competent hetero coiled coil of the Styela D protein and Xenopus keratin 8. Eur. J. Cell Biol. 79:2000;478-487.
11. Wang J., Karabinos A., Zimek A., Meyer M., Riemer D., Hudson C., et al. Cytoplasmic intermediate filament protein expression in tunicate development; a specific marker for the test cells. Eur. J. Cell Biol. 81:2002;302-311.27.
12. Weber K., Plessmann U., Ulrich W. Cytoplasmic intermediate filament proteins of invertebrates are closer to nuclear lamins than are vertebrate intermediate filament proteins; sequence characterization of two muscle proteins of a nematode. EMBO J. 8:1989;3221-3227.
13. Erber A., Riemer D., Bovenschulte M., Weber K. Molecular phylogeny of metazoan intermediate filament proteins. J. Mol. Evol. 47:1998;751-762.
14. Liu J., Ben-Shahar T.R., Riemer D., Treinin M., Spann P., Weber K., et al. Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes. Mol. Biol. Cell. 11:2000;3937-3947.
15. Fraser A.G., Kamath R.S., Zipperlen P., Martinez-Campos M., Sohrmann M., Ahringer J. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 408:2000;325-330.
16. Karabinos A., Schmidt H., Harborth J., Schnabel R., Weber K. Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development. Proc. Natl Acad. Sci. USA. 98:2001;7863-7868.
17. Francis R., Waterston R.H. Muscle cell attachement in Caenorhabditis elegans. J. Cell Biol. 114:1991;465-479.
18. Hresko M.C., Williams B.D., Waterston R.H. Assembly of body wall muscle and muscle cell attachment structures in Caenorhabditis elegans. J. Cell Biol. 124:1994;491-506.
19. Hresko M.C., Schriefer L.A., Shrimankar P., Waterston R.H. Myotactin, a novel hypodermal protein involved in muscle-cell adhesion in Caenorhabditis elegans. J. Cell Biol. 146:1999;659-672.
20. Karabinos A., Schulze E., Klisch T., Wang J., Weber K. Expression profiles of the essential intermediate filament (IF) protein A2 and the IF protein C2 in the nematode Caenorhabditis elegans. Mech. Dev. 117:2002;311-314.
21. Timmons L., Court D.L., Fire A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene. 263:2001;103-112.
22. Dodemont H., Riemer D., Ledger N., Weber K. Eight genes and alternative RNA processing pathways generate an unexpectedly large diversity of cytoplasmic intermediate filament proteins in the nematode Caenorhabditis elegans. EMBO J. 13:1994;2625-2638.
23. Citi S., D'Atri F., Parry D.A.D. Human and Xenopus cingulin a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly. J. Struct. Biol. 131:2000;135-145.
24. Yoon K.H., Yoon M., Moir R.D., Khuon S., Flitney F.W., Goldman R.D. Insights into the dynamic properties of keratin intermediate filaments in living epithelial cells. J. Cell Biol. 153:2001;503-516.
25. Kamath R.S., Fraser A.G., Dong Y., Poulin G., Durbin R., Gotta M., et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature. 421:2003;231-237.
26. Herrmann H., Aebi U. Intermediate filaments and their associates: multi-talented structural elements specifying cytoarchitecture and cytodynamics. Curr. Opin. Cell Biol. 12:2000;79-90.
27. Strelkov S.V., Herrmann H., Aebi U. Molecular architecture of intermediate filaments. BioEssays. 25:2003;243-251.
28. Sulston J.E., Hodgkin J. Methods. Wood W.B. The Nematode Caenorhabditis elegans. 1988;587-606 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
29. Praitis V., Casey E., Collar D., Austin J. Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics. 157:2001;1217-1226.
30. Hatzfeld M., Maier G., Franke W.W. Cytokeratin domains involved in heterotypic complex formation determined by in vitro binding assays. J. Mol. Biol. 197:1987;237-255.
31. Karabinos A., Schünemann J., Meyer M., Aebi U., Weber K. The single nuclear lamin of Caenorhabditis elegans forms in vitro stable intermediate filaments and paracrystals with a reduced axial periodicity. J. Mol. Biol. 325:2003;241-247.
32. Kirby C., Kusch M., Kemphues K. Specification of male development in Caenorhabditis elegans: the fem genes. Dev. Biol. 105:1990;234-239.