Polymorphism of a novel sodium ion channel blocker

Journal of Pharmaceutical Sciences

Volumn 92, Issue 10, 2003, Pages 2017-2026

  Cheung, Eugene Y ^a   Harris, Kenneth D M ^a   Johnston, Roy L ^a   Hadden, Kelly L ^b   Zakrzewski, Marek ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b PURDUE PHARMA L P   (United States)

Author keywords

Crystal structure determination; Genetic algorithm; Polymorphism; Powder X ray diffraction; Rietveld refinement

Indexed keywords

2 [[4 (4 FLUOROPHENOXYL)PHENYL]METHYLENE]HYDRAZINECARBOXAMIDE; ANTICONVULSIVE AGENT; SEMICARBAZONE DERIVATIVE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; ARTICLE; CRYSTAL STRUCTURE; DRUG DETERMINATION; GENETIC ALGORITHM; GENETIC POLYMORPHISM; NERVOUS SYSTEM FUNCTION; NEUROPATHIC PAIN; SODIUM CURRENT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY POWDER DIFFRACTION;

EID: 0141619295     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10434     Document Type: Article

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