Effects of chronic dizocilpine on acute pain and on mRNA expression of neuropeptides and the dopamine and glutamate receptors

Brain Research

Volumn 981, Issue 1-2, 2003, Pages 99-107

  Al Amin, Hassen A ^a   Saadé, Nayef E ^a   Khani, Munir ^a   Atweh, Samir ^a   Jaber, Mohamed ^b  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^b UNIVERSITÉ DE POITIERS   (France)

Author keywords

Acute pain; Dizocilpine; Dopamine; Glutamate; In situ hybridization; Neuropeptide

Indexed keywords

DIZOCILPINE; DOPAMINE; DOPAMINE RECEPTOR; DYNORPHIN; ENKEPHALIN; GLUTAMATE RECEPTOR; GLUTAMIC ACID; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPEPTIDE; OPIATE; SUBSTANCE P; AMINO ACID RECEPTOR BLOCKING AGENT; DIZOCILPINE MALEATE;

ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CINGULATE GYRUS; CONTROLLED STUDY; CORPUS STRIATUM; HOT PLATE TEST; HYPERALGESIA; IN SITU HYBRIDIZATION; LONG TERM CARE; MALE; NOCICEPTION; NONHUMAN; NUCLEUS ACCUMBENS; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRIFORM CORTEX; RAT; SENSORIMOTOR FUNCTION; ANIMAL; AUTORADIOGRAPHY; BIOSYNTHESIS; BRAIN; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HISTOLOGY; LOCOMOTION; METABOLISM; PAIN ASSESSMENT; REACTION TIME; SPRAGUE DAWLEY RAT; STEREOTYPY; TIME;

ANIMALS; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; BRAIN; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; HYPERALGESIA; IN SITU HYBRIDIZATION; LOCOMOTION; MALE; NEUROPEPTIDES; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, DOPAMINE; RECEPTORS, GLUTAMATE; RNA, MESSENGER; STEREOTYPED BEHAVIOR; TIME FACTORS;

EID: 0141575445     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(03)02988-3     Document Type: Article

References (43)

1. Angulo J.A., Williams A., Ledoux M., Watanabe Y., McEwen B.S. Elevation of striatal and accumbal preproenkephalin, preprotachykinin and preprodynorphin mRNA abundance subsequent to N-methyl-D-aspartate receptor blockade with MK-801. Brain Res. Mol. Brain Res. 29:1995;15-22.
2. Beckstead R.M. N-methyl-D-aspartate acutely increases proenkephalin mRNA in the rat striatum. Synapse. 21:1995;342-347.
3. Ben-Eliyahu S., Marek P., Vaccarino A.L., Mogil J.S., Sternberg W.F., Liebeskind J.C. The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat. Brain Res. 575:1992;304-308.
4. Bennett G.J. Update on the neurophysiology of pain transmission and modulation: focus on the NMDA-receptor. J. Pain Symptom Manage. 19:2000;S2-6.
5. Bhargava H.N., Thorat S.N. Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a kappa-opioid receptor agonist, in the mouse. Brain Res. 649:1994;111-116.
6. Bilsky E.J., Inturrisi C.E., Sadee W., Hruby V.J., Porreca F. Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective mu or delta opioid agonists in mice. Pain. 68:1996;229-237.
7. Celerier E., Laulin J., Larcher A., Le Moal M., Simonnet G. Evidence for opiate-activated NMDA processes masking opiate analgesia in rats. Brain Res. 847:1999;18-25.
8. Dunbar S., Yaksh T.L. Concurrent spinal infusion of MK801 blocks spinal tolerance and dependence induced by chronic intrathecal morphine in the rat. Anesthesiology. 84:1996;1177-1188.
9. Dunbar S.A., Yaksh T.L. Spinal infusion of N-methyl-D-aspartate antagonist MK801 induces hypersensitivity to the spinal alpha-2 agonist ST91 in the rat. J. Pharmacol. Exp. Ther. 281:1997;1219-1225.
10. Eliav E., Herzberg U., Ruda M.A., Bennett G.J. Neuropathic pain from an experimental neuritis of the rat sciatic nerve. Pain. 83:1999;169-182.
11. Fisher K., Fundytus M.E., Cahill C.M., Coderre T.J. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 77:1998;59-66.
12. Fisher K., Coderre T.J., Hagen N.A. Targeting the N-methyl-D-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions. J. Pain Symptom Manage. 20:2000;358-373.
13. Forman L.J. NMDA receptor antagonism produces antinociception which is partially mediated by brain opioids and dopamine. Life Sci. 64:1999;1877-1887.
14. Grass S., Hoffmann O., Xu X.J., Wiesenfeld-Hallin Z. N-Methyl-D-aspartate receptor antagonists potentiate morphine's antinociceptive effect in the rat. Acta Physiol. Scand. 158:1996;269-273.
15. Hajji M.D., Salin P., Kerkerian-Le Goff L. Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephalin but not on substance P expression in the rat striatum. Eur. J. Neurosci. 8:1996;917-926.
16. Hao J.X., Xu X.J. Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists. Pain. 66:1996;279-285.
17. Heinricher M.M., Morgan M.M., Tortorici V., Fields H.L. Disinhibition of off-cells and antinociception produced by an opioid action within the rostral ventromedial medulla. Neuroscience. 63:1994;279-288.
18. Hesselink M.B., Smolders H., De Boer A.G., Breimer D.D., Danysz W. Modifications of the behavioral profile of non-competitive NMDA receptor antagonists, memantine, amantadine and (+)MK-801 after chronic administration. Behav. Pharmacol. 10:1999;85-98.
19. Jaber M., Dumartin B., Sagne C., Haycock J.W., Roubert C., Giros B., Bloch B., Caron M.G. Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. Eur. J. Neurosci. 11:1999;3499-3511.
20. Jensen T.S., Yaksh T.L. The antinociceptive activity of excitatory amino acids in the rat brainstem: an anatomical and pharmacological analysis. Brain Res. 569:1992;255-267.
21. Jolkkonen J., Jenner P., Marsden C.D. Glutamatergic regulation of striatal peptide gene expression in rats. J. Neural Transm. Parkinson Dis. Dementia Sect. 10:1995;187-198.
22. Kim Y.I., Na H.S., Yoon Y.W., Han H.C., Ko K.H., Hong S.K. NMDA receptors are important for both mechanical and thermal allodynia from peripheral nerve injury in rats. Neuroreport. 8:1997;2149-2153.
23. Le Moine C., Bloch B. D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum. J. Comp. Neurol. 355:1995;418-426.
24. Lutfy K., Cai S.X., Woodward R.M., Weber E. Antinociceptive effects of NMDA and non-NMDA receptor antagonists in the tail flick test in mice. Pain. 70:1997;31-40.
25. Mao J., Price D.D., Hayes R.L., Lu J., Mayer D.J. Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain Res. 598:1992;271-278.
26. Mao J., Price D.D., Mayer D.J., Lu J., Hayes R.L. Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy. Brain Res. 576:1992;254-262.
27. Marek P., Ben-Eliyahu S., Vaccarino A.L., Liebeskind J.C. Delayed application of MK-801 attenuates development of morphine tolerance in rats. Brain Res. 558:1991;163-165.
28. Marek P., Ben-Eliyahu S., Gold M., Liebeskind J.C. Excitatory amino acid antagonists (kynurenic acid and MK-801) attenuate the development of morphine tolerance in the rat. Brain Res. 547:1991;77-81.
29. Noailles P.A., Villegas M., Ledoux M., Lucas L.R., McEwen B.S., Angulo J.A. Acute treatment with the N-methyl-D-aspartate receptor antagonist MK-801: effect of concurrent administration of haloperidol or scopolamine on preproenkephalin mRNA levels of the striatum and nucleus accumbens of the rat brain. Neurosci. Lett. 202:1996;165-168.
30. Somers D.L., Beckstead R.M. N-Methyl-D-aspartate receptor antagonism alters substance P and met5-enkephalin biosynthesis in neurons of the rat striatum. J. Pharmacol. Exp. Ther. 262:1992;823-833.
31. Suh H., Song D., Huh S., Kim Y.H. Differential potentiative effects of glutamate receptor antagonists in the production of antinociception induced by opioids administered intrathecally in the mouse. Brain Res. Bull. 52:2000;143-150.
32. Suh H.W., Song D.K., Kim Y.H., Yoo J.S., Tseng L.F. Differential antagonism by MK-801 against antinociception induced by opioid receptor agonists administered supraspinally in mice. Eur. J. Pharmacol. 263:1994;217-221.
33. Sutton J.L., Maccecchini M.L., Kajander K.C. The kainate receptor antagonist 2S,4R-4-methylglutamate attenuates mechanical allodynia and thermal hyperalgesia in a rat model of nerve injury. Neuroscience. 91:1999;283-292.
34. Tolle T.R., Berthele A., Zieglgansberger W., Seeburg P.H., Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J. Neurosci. 13:1993;5009-5028.
35. Vaccarino A.L., Clavier M.C. Blockade of tolerance to stress-induced analgesia by MK-801 in mice. Pharmacol. Biochem. Behav. 56:1997;435-439.
36. Verma A., Kulkarni S.K. Role of D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptors in morphine tolerance and dependence in mice. Eur. Neuropsychopharmacol. 5:1995;81-87.
37. Wei H.B., Jakeman L.B., Hunter J.C., Bonhaus D.W. Pharmacological characterization of N-methyl-D-aspartate receptors in spinal cord of rats with a chronic peripheral mononeuropathy. Neuropharmacology. 36:1997;1561-1569.
38. Wong C.S., Cherng C.H., Ho S.T. Clinical applications of excitatory amino acid antagonists in pain management. Acta Anaesthesiol. Sin. 33:1995;227-232.
39. Yamamoto T., Yaksh T.L. Effects of intrathecal strychnine and bicuculline on nerve compression-induced thermal hyperalgesia and selective antagonism by MK-801. Pain. 54:1993;79-84.
40. Zhang F., Van Bree L., Albala N., Verslype M., Vanderhaeghen J.J. NMDA receptor antagonist MK-801 down-regulates rat striatal proenkephalin and protachykinin mRNAs. Neurochem. Int. 28:1996;189-192.
41. Zhao G.M., Bhargava H.N. Effect of antagonism of the NMDA receptor on tolerance to [D-Pen2,D-Pen5]enkephalin, a delta 1-opioid receptor agonist. Peptides. 17:1996;233-236.
42. Zushida K., Kamei J. Effect of MK-801 on the antinociceptive effect of [D-Ala(2),N-MePhe(4), Gly-ol(5)]enkephalin in diabetic mice. Br. J. Pharmacol. 448:2002;39-44.
43. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1986.