Plasma binding of trichloroacetic acid in mice, rats, and humans under cancer bioassay and environmental exposure conditions

Drug Metabolism and Disposition

Volumn 31, Issue 10, 2003, Pages 1203-1207

  Lumpkin, Michael H ^b   Bruckner, James V ^c   Campbell, Jerry L ^a   Dallas, Cham E ^c   White, Catherine A ^c   Fisher, Jeffrey W ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b Clayton Group Services Inc   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRINKING WATER; TETRACHLOROETHYLENE; TRICHLOROACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOASSAY; CANCER BIOASSAY; CANCER RISK; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE LIVER FUNCTION RELATION; DOSE RESPONSE; DRUG BINDING; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG UPTAKE; ENVIRONMENTAL EXPOSURE; EQUILIBRIUM DIALYSIS; HUMAN; MEAN RESIDENCE TIME; MOUSE; NONHUMAN; NONSATURABLE SITE MODEL; PRIORITY JOURNAL; RAT; SIMULATION; SINGLE SATURABLE SITE MODEL; SPECIES DIFFERENCE; TWO SATURABLE SITE MODEL; WATER CONTAMINATION;

ANIMALS; BIOLOGICAL ASSAY; ENVIRONMENTAL EXPOSURE; HUMANS; MALE; MICE; MODELS, BIOLOGICAL; NEOPLASMS; PREDICTIVE VALUE OF TESTS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; TRICHLOROACETIC ACID;

ANIMALIA; RODENTIA;

EID: 0141569630     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.10.1203     Document Type: Article

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