Stereoselective pharmacokinetics and metabolism of flobufen in guinea pigs

Chirality

Volumn 15, Issue 8, 2003, Pages 724-729

  Trejtnar, František ^a   Král, Radim ^a   Pávek, Petr ^a   Wsól, Vladimír ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

Antiinflammatory drugs; Chiral; Enantiomer; Enantioselective disposition; Metabolic elimination; Pharmacokinetics; Stereoisomerism

Indexed keywords

4 (2,4 DIFLUOROPHENYL)PHENYLACETIC ACID; 4 DIHYDROFLOBUFEN; FLOBUFEN; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYLACETIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHIRALITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; ENANTIOMER; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOMODULATION; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEREOCHEMISTRY; STEREOISOMERISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; BIOTRANSFORMATION; BUTYRIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GUINEA PIGS; MALE; STEREOISOMERISM;

EID: 0141566926     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/chir.10288     Document Type: Article

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