Identification of selected psychopharmaceuticals and their metabolites in hair by LC/ESI-CID/MS and LC/MS/MS

Forensic Science International

Volumn 113, Issue 1-3, 2000, Pages 415-421

  Müller, Claudia ^a   Vogt, Susanne ^a   Goerke, Rolf ^a   Kordon, Andreas ^b   Weinmann, Wolfgang ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Citalopram; Electrospray ionisation; Hair analysis; LCMS; Maprotiline; Pipamperone

Indexed keywords

CITALOPRAM; DRUG METABOLITE; MAPROTILINE; NEUROLEPTIC AGENT; PIPAMPERONE; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

CASE REPORT; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG OVERDOSE; DRUG SCREENING; EXTRACTION; HAIR ANALYSIS; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; SOLID PHASE EXTRACTION;

EID: 0141558396     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0379-0738(00)00202-4     Document Type: Conference Paper

References (15)

1. Kintz P. Drug Testing in Hair. 1996;CRC Press, Bocan Raton, FL. ISBN 0-8493-8112-6.
2. Potsch L., Skopp G., Moeller M.R. Zum Suchtmittelnachweis in Haaren. Eine biochemische Erklarung fur den endogenen Einbau von Pharmaka und illegalen Drogen ins Haar wahrend der Anagenphase. Rechtsmedizin. 7:1996;1-5.
3. Cirimele V., Kintz P., Ludes B. Screening for forensically relevant benzodiazepines in human hair by gas chromatography-negative ion chemical ionization-mass spectrometry. J. Chromatogr. 700:(1-2):1997;119-129.
4. Cirimele V., Kintz P., Staub C., Mangin P. Testing human hair for fluitrazepam and 7- amino-flunitrazepam by GC-MS-NCI. J. Forensic Sci. 84:(1-3):1997;189-200.
5. Ishiyama I., Nagai T., Toshida S. Detection of basic drugs (methamphetamine, antidepressants and nicotine) from human hair. J. Forensic Sci. 28:1983;380-385.
6. Kintz P., Ludes B., Mangin P. Detection of drugs in human hair using Abott Adx, with confirmation by gas chromatography/mass spectrometry (GC-MS). J. Forensic Sci. 37:1992;328-331.
7. Kintz P., Tracqui A., Mangin P. Detection of drugs in human hair for clinical and forensic applications. Int. J. Leg. Med. 105:1992;1-4.
8. Tracqui A., Kreissig P., Kintz P., Pouliquen A., Mangin P. Hum. Exp. Toxicol. 11:1992;363-367.
9. Pragst F., Rothe M., Hunger J., Thor S. Structural and concentraction effects on the deposition of tricyclic antidepressant in human hair. J. Forensic Sci. 84:1997;225-236.
10. Pragst F., Rothe M., Spiegel K., Sporkert F. illeagal and therapeutic drug concentrations in hair segments - a timetable of drug exposure? Forensic Sci. Rev. 10:(2):1998;82-111.
11. Drummer O.H., Cooper F.J. Detection of anti-depressant drugs in hair. Proceedings of the Hair Analysis in Forensic Toxicology Workshop, Abu Dhabi, November 19-23 :1995.
12. Weinmann W., Wiedemann A., Eppinger B., Renz M., Svoboda M. Screening for drugs in serum by Electrospray Ionization/Collision - Induced Dissociation and library searching. J. Am. Soc. Mass Spectrom. 10:1999;1028-1037.
13. Weinmann W., Muller C., Lehmannn N., Wiedemann A., Svoboda M. Use of an Ionspray-MS/MS Liabary for Drug Screening - Poster presentation. 37th TIAFT Triennal Meeting, September 5-9 :1999;. Cracow, Poland.
14. X Diamond F., E Vickery W., DeKanel J. Extraction of Benzoylegonine (Cocainemetabolite) and Opiates (Codeine and Morphine) from urine samples using the Zymark RapaidTraceTM. J. Anal. Toxicol. 20:1996;587-591.
15. Weinmann W., Svoboda M. Fast screenig for drugs of abuse by Solid-Phase-Extraction combinded with Flow-Injection Ionspray-Tandem Mass Spectrometry. J. Anal. Toxicol. 22:1998;319-328.