An ile to met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced β2-adrenergic receptor stimulation

Pharmacogenetics

Volumn 13, Issue 9, 2003, Pages 535-541

  Small, Kersten M ^a   Brown, Kari M ^a   Theiss, Cheryl T ^a   Seman, Carrie A ^a   Weiss, Scott T ^b   Liggett, Stephen B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Adenylyl cyclase; Lung; Polymorphism; Signal transduction

Indexed keywords

ADENYLATE CYCLASE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

ALLELE; ARTICLE; ASIAN; ASTHMA; CATALYSIS; CAUCASIAN; CONTROLLED STUDY; DNA ISOLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE FREQUENCY; GENE LOCATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETIC VARIABILITY; GENOMICS; HUMAN; HUMAN CELL; LIGAND BINDING; LUNG ALVEOLUS CELL; NEGRO; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; AFRICAN CONTINENTAL ANCESTRY GROUP; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CATALYTIC DOMAIN; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOMICS; HUMANS; ISOLEUCINE; ISOPROTERENOL; LUNG; METHIONINE; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ADRENERGIC, BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION; VARIATION (GENETICS);

EID: 0141538183     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200309000-00002     Document Type: Article

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