Amide rotamers of N-acetyl-1,3-dimethyltetrahydroisoquinolines: Synthesis, variable temperature NMR spectroscopy and molecular modelling

Tetrahedron

Volumn 59, Issue 42, 2003, Pages 8337-8345

  De Koning, Charles B ^a   Van Otterlo, Willem A L ^a   Michael, Joseph P ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Amides; Isoquinolines; Mercury and compounds; Molecular modelling; NMR; Rotamers

Indexed keywords

2 [2 [1 (ACETYLAMINO)ETHYL] 6 (BENZYLOXY) 3,5 DIMETHOXYPHENYL] 1 METHYLETHYL METHANESULFONATE; AMIDE; N ACETYL 5 BENZYLOXY 6,8 DIMETHOXY 1,3 DIMETHYL 1,2,3,4 TETRAHYDROISOQUINOLINE; N [1 (2 ALLYL 3 BENZYLOXY 4,6 DIMETHOXYPHENYL)ETHYL]ACETAMIDE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CYCLIZATION; DRUG SYNTHESIS; HIGH TEMPERATURE; ISOMER; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RACEMIC MIXTURE;

EID: 0141532303     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.09.001     Document Type: Article

References (41)

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