-
1
-
-
0036483901
-
Deadly encounter: Ubiquitin meets apoptosis
-
Jesenberger V, Jentsch S. Deadly encounter: ubiquitin meets apoptosis. Nat Rev Mol Cell Biol. 2002;3:112-121.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 112-121
-
-
Jesenberger, V.1
Jentsch, S.2
-
2
-
-
0036240701
-
The proteasome: A novel target for cancer chemotherapy
-
Almond JB, Cohen GM. The proteasome: a novel target for cancer chemotherapy. Leukemia. 2002;16:433-443.
-
(2002)
Leukemia
, vol.16
, pp. 433-443
-
-
Almond, J.B.1
Cohen, G.M.2
-
3
-
-
0029564960
-
Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells
-
Imajoh-Ohmi S, Kawaguchi T, Sugiyama S, et al. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells. Biochem Biophys Res Commun. 1995;217:1070-1077.
-
(1995)
Biochem Biophys Res Commun
, vol.217
, pp. 1070-1077
-
-
Imajoh-Ohmi, S.1
Kawaguchi, T.2
Sugiyama, S.3
-
4
-
-
0032481131
-
Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53
-
Herrmann JL, Briones F Jr, Brisbay S, et al. Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53. Oncogene. 1998;17:2889-2899.
-
(1998)
Oncogene
, vol.17
, pp. 2889-2899
-
-
Herrmann, J.L.1
Briones F., Jr.2
Brisbay, S.3
-
5
-
-
0030962262
-
p53-dependent induction of apoptosis by proteasome inhibitors
-
Lopes UG, Erhardt P, Yao R, et al. p53-dependent induction of apoptosis by proteasome inhibitors. J Biol Chem. 1997;272:12893-12896.
-
(1997)
J Biol Chem
, vol.272
, pp. 12893-12896
-
-
Lopes, U.G.1
Erhardt, P.2
Yao, R.3
-
6
-
-
0031034160
-
Activation of the cell death program by inhibition of proteasome function
-
Drexler HC. Activation of the cell death program by inhibition of proteasome function. Proc Natl Acad Sci U S A. 1997;94:855-860.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 855-860
-
-
Drexler, H.C.1
-
7
-
-
9544239345
-
Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons
-
Sadoul R, Fernandez PA, Quiquerez AL, et al. Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons. EMBO J. 1996;15:3845-3852.
-
(1996)
EMBO J
, vol.15
, pp. 3845-3852
-
-
Sadoul, R.1
Fernandez, P.A.2
Quiquerez, A.L.3
-
8
-
-
0029762871
-
Proteasomes play an essential role in thymocyte apoptosis
-
Grimm LM, Goldberg AL, Poirier GG, et al. Proteasomes play an essential role in thymocyte apoptosis. EMBO J. 1996;15:3835-3844.
-
(1996)
EMBO J
, vol.15
, pp. 3835-3844
-
-
Grimm, L.M.1
Goldberg, A.L.2
Poirier, G.G.3
-
9
-
-
0033563113
-
Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells
-
Zhang XM, Lin H, Chen C, et al. Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells. Biochem J. 1999;340:127-133.
-
(1999)
Biochem J
, vol.340
, pp. 127-133
-
-
Zhang, X.M.1
Lin, H.2
Chen, C.3
-
10
-
-
0032885388
-
Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
-
Earnshaw WC, Martins LM, Kaufmann SH. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem. 1999;68:383-424.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
12
-
-
15644364847
-
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
-
Woo M, Hakem R, Soengas MS, et al. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 1998;12:806-819.
-
(1998)
Genes Dev
, vol.12
, pp. 806-819
-
-
Woo, M.1
Hakem, R.2
Soengas, M.S.3
-
13
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA, et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. 1999;59:2615-2622.
-
(1999)
Cancer Res
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
-
14
-
-
0037192316
-
Ubiquitin-proteasome pathway as a new target for the prevention of restenosis
-
Meiners S, Laule M, Rother W, et al. Ubiquitin-proteasome pathway as a new target for the prevention of restenosis. Circulation. 2002;105:483-489.
-
(2002)
Circulation
, vol.105
, pp. 483-489
-
-
Meiners, S.1
Laule, M.2
Rother, W.3
-
15
-
-
0034037622
-
Proteasome inhibition measurements: Clinical application
-
Lightcap ES, McCormack TA, Pien CS, et al. Proteasome inhibition measurements: clinical application. Clin Chem. 2000;46:673-683.
-
(2000)
Clin Chem
, vol.46
, pp. 673-683
-
-
Lightcap, E.S.1
McCormack, T.A.2
Pien, C.S.3
-
17
-
-
0030048396
-
Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta
-
Geng YJ, Wu Q, Muszynski M, et al. Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta. Arterioscler Thromb Vasc Biol. 1996;16:19-27.
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 19-27
-
-
Geng, Y.J.1
Wu, Q.2
Muszynski, M.3
-
18
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 1998;17:1675-1687.
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
-
19
-
-
0031470991
-
Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells
-
Geng YJ, Henderson LE, Levesque EB, et al. Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1997;17:2200-2208.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2200-2208
-
-
Geng, Y.J.1
Henderson, L.E.2
Levesque, E.B.3
-
20
-
-
0030034534
-
Distribution of cell replication and apoptosis in atherosclerotic plaques of cholesterol-fed rabbits
-
Kockx MM, De Meyer GR, Muhring J, et al. Distribution of cell replication and apoptosis in atherosclerotic plaques of cholesterol-fed rabbits. Atherosclerosis. 1996;120:115-124.
-
(1996)
Atherosclerosis
, vol.120
, pp. 115-124
-
-
Kockx, M.M.1
De Meyer, G.R.2
Muhring, J.3
-
21
-
-
0028997321
-
Apoptosis participates in cellularity regulation during rat aortic intimal thickening
-
Bochaton-Piallat ML, Gabbiani F, Redard M, et al. Apoptosis participates in cellularity regulation during rat aortic intimal thickening. Am J Pathol. 1995;146:1059-1064.
-
(1995)
Am J Pathol
, vol.146
, pp. 1059-1064
-
-
Bochaton-Piallat, M.L.1
Gabbiani, F.2
Redard, M.3
-
22
-
-
0032076204
-
Apoptosis of vascular smooth muscle cells in atherosclerosis
-
Bennett MR, Boyle JJ. Apoptosis of vascular smooth muscle cells in atherosclerosis. Atherosclerosis. 1998;138:3-9.
-
(1998)
Atherosclerosis
, vol.138
, pp. 3-9
-
-
Bennett, M.R.1
Boyle, J.J.2
-
23
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
-
Palombella VJ, Rando OJ, Goldberg AL, et al. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell. 1994;78:773-785.
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
-
24
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock KL, Gramm C, Rothstein L, et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell. 1994;78:761-771.
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
-
25
-
-
0032500793
-
Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
-
Bennett M, Macdonald K, Chan SW, et al. Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. Science. 1998;282:290-293.
-
(1998)
Science
, vol.282
, pp. 290-293
-
-
Bennett, M.1
Macdonald, K.2
Chan, S.W.3
-
26
-
-
0029952441
-
In vivo ubiquitination and proteasome-mediated degradation of p53
-
Maki CG, Huibregtse JM, Howley PM. In vivo ubiquitination and proteasome-mediated degradation of p53. Cancer Res. 1996;56:2649-2654.
-
(1996)
Cancer Res
, vol.56
, pp. 2649-2654
-
-
Maki, C.G.1
Huibregtse, J.M.2
Howley, P.M.3
-
27
-
-
0030016329
-
Apoptosis induction resulting from proteasome inhibition
-
Shinohara K, Tomioka M, Nakano H, et al. Apoptosis induction resulting from proteasome inhibition. Biochem J. 1996;317:385-388.
-
(1996)
Biochem J
, vol.317
, pp. 385-388
-
-
Shinohara, K.1
Tomioka, M.2
Nakano, H.3
-
28
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano M, Tam SW, Theodoras AM, et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science. 1995;269:682-685.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
-
29
-
-
0032429122
-
Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
-
An B, Goldfarb RH, Siman R, et al. Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts. Cell Death Differ. 1998;5:1062-1075.
-
(1998)
Cell Death Differ
, vol.5
, pp. 1062-1075
-
-
An, B.1
Goldfarb, R.H.2
Siman, R.3
-
30
-
-
0033623317
-
Overexpression of truncated IkappaBalpha induces TNF-alpha-dependent apoptosis in human vascular smooth muscle cells
-
Obara H, Takayanagi A, Hirahashi J, et al. Overexpression of truncated IkappaBalpha induces TNF-alpha-dependent apoptosis in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2000;20:2198-2204.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2198-2204
-
-
Obara, H.1
Takayanagi, A.2
Hirahashi, J.3
-
31
-
-
0034635952
-
Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression
-
Li B, Dou QP. Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression. Proc Natl Acad Sci USA. 2000;97:3850-3855.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3850-3855
-
-
Li, B.1
Dou, Q.P.2
-
32
-
-
0034808363
-
Proteasome inhibitors sensitize human vascular smooth muscle cells to Fas (CD95)-mediated death
-
Kim K. Proteasome inhibitors sensitize human vascular smooth muscle cells to Fas (CD95)-mediated death. Biochem Biophys Res Commun. 2001;281:305-310.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 305-310
-
-
Kim, K.1
-
33
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 1995;376:37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
-
34
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, et al. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 1996;86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
-
35
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula SM, Ahmad M, Fernandes-Alnemri T, et al. Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci U S A. 1996;93:14486-14491.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14486-14491
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
-
36
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91:479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
|