-
1
-
-
0036105516
-
High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICPMS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOFMS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine
-
ABOU-SHAKRA, F. R., SAGE, A. B., CASTRO-PEREZ, J., NICHOLSON, J. K., LINDON, J. C., SCARFE, G. B. and WILSON, I. D., 2002, High-performance liquid chromatography-UV diode array, inductively coupled plasma mass spectrometry (ICPMS) and orthogonal acceleration time-of-flight mass spectrometry (oa-TOFMS) applied to the simultaneous detection and identification of metabolites of 4-bromoaniline in rat urine. Chromatographia, 55S, S9-S13.
-
(2002)
Chromatographia
, vol.55 S
-
-
Abou-Shakra, F.R.1
Sage, A.B.2
Castro-Perez, J.3
Nicholson, J.K.4
Lindon, J.C.5
Scarfe, G.B.6
Wilson, I.D.7
-
3
-
-
0031843611
-
Biotransformation of cerivastatin in mice, rats and dogs in vivo
-
BOBERG, M., ANGERBAUER, R., KANHAI, W. K., KERN, A., RADTKE, M. and STEINKE, W., 1998, Biotransformation of cerivastatin in mice, rats and dogs in vivo. Drug Metabolism and Disposition, 26, 640-652.
-
(1998)
Drug Metabolism and Disposition
, vol.26
, pp. 640-652
-
-
Boberg, M.1
Angerbauer, R.2
Kanhai, W.K.3
Kern, A.4
Radtke, M.5
Steinke, W.6
-
4
-
-
0035115178
-
In vivo metabolism of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine in mice: Glucosidation as the principal metabolic route
-
CHMELA, Z., VESELY, J., LEMR, K., RYPKA, M., HANUS, J., HAVLICEK, L., KRYSTOF, V., MICHNOVA, L., FUKSOVA, K. and LUKES, J., 2001, In vivo metabolism of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine in mice: glucosidation as the principal metabolic route. Drug Metabolism and Disposition, 29, 326-334.
-
(2001)
Drug Metabolism and Disposition
, vol.29
, pp. 326-334
-
-
Chmela, Z.1
Vesely, J.2
Lemr, K.3
Rypka, M.4
Hanus, J.5
Havlicek, L.6
Krystof, V.7
Michnova, L.8
Fuksova, K.9
Lukes, J.10
-
5
-
-
0029863309
-
Quantitative structure-metabolism relationships for substituted benzoates in the rabbit, prediction of urinary excretion of glycine and glucuronide conjugates
-
CUPID, B. C., BEDDELL, C. R., WILSON, I. D., LINDON, J. C. and NICHOLSON, J. K., 1996, Quantitative structure-metabolism relationships for substituted benzoates in the rabbit, prediction of urinary excretion of glycine and glucuronide conjugates. Xenobiotica, 26, 157-176.
-
(1996)
Xenobiotica
, vol.26
, pp. 157-176
-
-
Cupid, B.C.1
Beddell, C.R.2
Wilson, I.D.3
Lindon, J.C.4
Nicholson, J.K.5
-
6
-
-
0032970618
-
Quantitative structure-metabolism relationships (QSMR) using computational chemistry: Pattern recognition analysis and statistical prediction of phase II conjugation reactions of substituted benzoic acids in the rat
-
CUPID, B. C., HOLMES, E., WILSON, I. D., LINDON, J. C. and NICHOLSON, J. K., 1999, Quantitative structure-metabolism relationships (QSMR) using computational chemistry: pattern recognition analysis and statistical prediction of phase II conjugation reactions of substituted benzoic acids in the rat. Xenobiotica, 29, 22-42.
-
(1999)
Xenobiotica
, vol.29
, pp. 22-42
-
-
Cupid, B.C.1
Holmes, E.2
Wilson, I.D.3
Lindon, J.C.4
Nicholson, J.K.5
-
7
-
-
0030977987
-
Elucidation of phase I and phase II metabolic pathways of rhein: Species differences and their potential relevance
-
DAHMS, M., LOTZ, R., LANG, W., RENNER, U., BAYER, E. and SPAHN-LANGGUTH, H., 1997, Elucidation of phase I and phase II metabolic pathways of rhein: species differences and their potential relevance. Drug Metabolism and Disposition, 25, 442-452.
-
(1997)
Drug Metabolism and Disposition
, vol.25
, pp. 442-452
-
-
Dahms, M.1
Lotz, R.2
Lang, W.3
Renner, U.4
Bayer, E.5
Spahn-Langguth, H.6
-
8
-
-
0016110206
-
N-glucoside formation as a detoxification mechanism in mammals
-
DUGGAN, D. E., BALDWIN, J., ARISON, B. H. and RHODES, R. E., 1974, N-glucoside formation as a detoxification mechanism in mammals. Journal of Pharmacology and Experimental Therapeutics, 190, 563-569.
-
(1974)
Journal of Pharmacology and Experimental Therapeutics
, vol.190
, pp. 563-569
-
-
Duggan, D.E.1
Baldwin, J.2
Arison, B.H.3
Rhodes, R.E.4
-
9
-
-
0026495267
-
Quantitative structure-metabolism relationships for substituted benzoic acids in the rat: Computational chemistry, NMR spectroscopy and pattern recognition studies
-
GHAURI, F. Y. K., BLACKLEDGE, C. A., GLEN, R. C., LINDON, J. C., BEDELL, C. R., WILSON, I. D. and NICHOLSON, J. K., 1992, Quantitative structure-metabolism relationships for substituted benzoic acids in the rat: computational chemistry, NMR spectroscopy and pattern recognition studies. Biochemical Pharmacology, 44, 1935-1946.
-
(1992)
Biochemical Pharmacology
, vol.44
, pp. 1935-1946
-
-
Ghauri, F.Y.K.1
Blackledge, C.A.2
Glen, R.C.3
Lindon, J.C.4
Bedell, C.R.5
Wilson, I.D.6
Nicholson, J.K.7
-
10
-
-
0011116365
-
Isolation and identification of a polar sulfamethazine 'metabolite' from swine
-
GIERA, D. D., ABDULLA, R. F., OCCOLOWITZ, J. L., DORMAN, D. E., MERTZ, J. L. and SIECK, R. F., 1982, Isolation and identification of a polar sulfamethazine 'metabolite' from swine. Journal of Agricultural and Food Chemistry, 30, 260-266.
-
(1982)
Journal of Agricultural and Food Chemistry
, vol.30
, pp. 260-266
-
-
Giera, D.D.1
Abdulla, R.F.2
Occolowitz, J.L.3
Dorman, D.E.4
Mertz, J.L.5
Sieck, R.F.6
-
11
-
-
0022969633
-
The metabolism of aromatic amines
-
GORROD, J. W. and MANSON, D., 1986, The metabolism of aromatic amines. Xenobiotics, 16, 933-955.
-
(1986)
Xenobiotics
, vol.16
, pp. 933-955
-
-
Gorrod, J.W.1
Manson, D.2
-
12
-
-
0023901527
-
Metabolic fate of indeloxazine: Hydrochloride α-glucoside formation in rats
-
KAMIMURA, H., KAWAI, R. and KUDO, H., 1988, Metabolic fate of indeloxazine: hydrochloride α-glucoside formation in rats. Xenobiotica, 18, 141-149.
-
(1988)
Xenobiotica
, vol.18
, pp. 141-149
-
-
Kamimura, H.1
Kawai, R.2
Kudo, H.3
-
13
-
-
0026599889
-
α-glucoside formation of xenobiotics by rat liver α-glucosidases
-
KAMIMURA, H., OGATA, H. and TAKAHARA, H., 1992, α-Glucoside formation of xenobiotics by rat liver α-glucosidases. Drug Metabolism and Disposition, 20, 309-315.
-
(1992)
Drug Metabolism and Disposition
, vol.20
, pp. 309-315
-
-
Kamimura, H.1
Ogata, H.2
Takahara, H.3
-
14
-
-
0345164363
-
Isolation and identification of bromfenac glucoside from rat bile
-
KIRKMAN, S. K., ZHANG, M. Y., HORWATT, P. M. and SCATINA, J., 1998, Isolation and identification of bromfenac glucoside from rat bile. Drug Metabolism and Disposition, 26, 720-723.
-
(1998)
Drug Metabolism and Disposition
, vol.26
, pp. 720-723
-
-
Kirkman, S.K.1
Zhang, M.Y.2
Horwatt, P.M.3
Scatina, J.4
-
15
-
-
0037214092
-
Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration
-
MAJOR, H. J., CASTRO-PEREZ, J., NICHOLSON, J. K. and WILSON, I. D., 2003, Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration. Rapid Communications in Mass Spectrometry, 17, 76-80.
-
(2003)
Rapid Communications in Mass Spectrometry
, vol.17
, pp. 76-80
-
-
Major, H.J.1
Castro-Perez, J.2
Nicholson, J.K.3
Wilson, I.D.4
-
16
-
-
0022640573
-
Metabolism of 4,4′-methylenebis(2-chloroaniline) by canine liver and kidney slices
-
MANIS, M. O. and BRASELTON, W. E., 1986, Metabolism of 4,4′-methylenebis(2-chloroaniline) by canine liver and kidney slices. Drug Metabolism and Disposition, 14, 166-174.
-
(1986)
Drug Metabolism and Disposition
, vol.14
, pp. 166-174
-
-
Manis, M.O.1
Braselton, W.E.2
-
17
-
-
0023007901
-
Hopantenic acid β-glucoside as a new urinary metabotite of calcium hopantenate in dogs
-
NAKANO, K., ANDO, H., SUGAWARA, Y., OHASHI, M. and HARIGAYA, S., 1986, Hopantenic acid β-glucoside as a new urinary metabotite of calcium hopantenate in dogs. Drug Metabolism and Disposition, 14, 740-745.
-
(1986)
Drug Metabolism and Disposition
, vol.14
, pp. 740-745
-
-
Nakano, K.1
Ando, H.2
Sugawara, Y.3
Ohashi, M.4
Harigaya, S.5
-
18
-
-
0033995198
-
High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: Application to the metabolites of 4-bromoaniline
-
NICHOLSON, J. K., LINDON, J. C., SCARFE, G., WILSON, I. D., ABOU-SHAKRA, F., CASTRO-PEREZ, J., EATON, A. and PREECE, S., 2000, High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline. Analyst, 125, 235-236.
-
(2000)
Analyst
, vol.125
, pp. 235-236
-
-
Nicholson, J.K.1
Lindon, J.C.2
Scarfe, G.3
Wilson, I.D.4
Abou-Shakra, F.5
Castro-Perez, J.6
Eaton, A.7
Preece, S.8
-
19
-
-
0021743386
-
Evidence for the transformation of sulfamethazine to its N4-glucopyranosyl cerivative in swine liver during frozen storage
-
PARKS, O. W., 1984, Evidence for the transformation of sulfamethazine to its N4-glucopyranosyl cerivative in swine liver during frozen storage. Journal of the Association of Official Analytical Chemists, 67, 566-569.
-
(1984)
Journal of the Association of Official Analytical Chemists
, vol.67
, pp. 566-569
-
-
Parks, O.W.1
-
21
-
-
0018657507
-
The primary aromatic amines: Their biological properties and structure-activity relationships
-
RADOMSKI, J. L., 1979, The primary aromatic amines: their biological properties and structure-activity relationships. Annual Reviews in Pharmacological Toxicology, 19, 129-157.
-
(1979)
Annual Reviews in Pharmacological Toxicology
, vol.19
, pp. 129-157
-
-
Radomski, J.L.1
-
22
-
-
0025093518
-
Identification of glucose conjugates as major urinary metabolites of cannabidiol in the dog
-
SAMARA, E., BIALER, M. and HARVEY, D. J., 1990, Identification of glucose conjugates as major urinary metabolites of cannabidiol in the dog. Xenobiotica, 20, 177-183.
-
(1990)
Xenobiotica
, vol.20
, pp. 177-183
-
-
Samara, E.1
Bialer, M.2
Harvey, D.J.3
-
23
-
-
0036260363
-
Structure-metabolism relationships of substituted anilines: Prediction of N-acetylation and N-oxanillic acid formation using computational chemistry
-
SCARFE, G. B., WILSON, I. D., WARNE, M. A., HOLMES, E., NICHOLSON, J. K. and LINDON, J. C., 2002a, Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanillic acid formation using computational chemistry. Xenobiotica, 32, 267-277.
-
(2002)
Xenobiotica
, vol.32
, pp. 267-277
-
-
Scarfe, G.B.1
Wilson, I.D.2
Warne, M.A.3
Holmes, E.4
Nicholson, J.K.5
Lindon, J.C.6
-
24
-
-
0036264047
-
13C]-acetanilide in the rat
-
13C]-acetanilide in the rat. Xenobiotica, 32, 325-337.
-
(2002)
Xenobiotica
, vol.32
, pp. 325-337
-
-
Scarfe, G.B.1
Nicholson, J.K.2
Lindon, J.C.3
Wilson, I.D.4
Taylor, S.5
Clayton, E.6
Wright, E.7
-
25
-
-
0022551881
-
Product enatioselectivity in the N-glucosylation of amobarbital
-
SOINE, W. H., SOINE, P. J., OVERTON, B. W. and GARRETTSON, L. K., 1986, Product enatioselectivity in the N-glucosylation of amobarbital. Drug Metabolism and Disposition, 14, 619-621.
-
(1986)
Drug Metabolism and Disposition
, vol.14
, pp. 619-621
-
-
Soine, W.H.1
Soine, P.J.2
Overton, B.W.3
Garrettson, L.K.4
-
26
-
-
0034625615
-
Application of mass spectrometry for identification and structural studies of flavonoid glycosides
-
STOBIECKI, M., 2000, Application of mass spectrometry for identification and structural studies of flavonoid glycosides. Phytochemisty, 54, 327-256.
-
(2000)
Phytochemisty
, vol.54
, pp. 327-256
-
-
Stobiecki, M.1
-
27
-
-
0018665614
-
Metabolic fate of phenobarbital in man. N-glucoside formation
-
TANG, B. K., KAKLOW, W. and GREY, A. A., 1979, Metabolic fate of phenobarbital in man. N-glucoside formation. Drug Metabolism and Disposition, 7, 315-318.
-
(1979)
Drug Metabolism and Disposition
, vol.7
, pp. 315-318
-
-
Tang, B.K.1
Kaklow, W.2
Grey, A.A.3
-
28
-
-
0018141946
-
Amobarbital metabolism in man: N-glucoside formation
-
TANG, B. K., KAKLOW, W. and GREY, A. A., 1978, Amobarbital metabolism in man: N-glucoside formation. Research Communications in Chemical Pathology and Pharmacology, 21, 45-53.
-
(1978)
Research Communications in Chemical Pathology and Pharmacology
, vol.21
, pp. 45-53
-
-
Tang, B.K.1
Kaklow, W.2
Grey, A.A.3
-
29
-
-
0024316201
-
New metabolites of the drug 5-aminosalicylic acid, I: N-b-D-glucopyranosyl-5-aminosalicylic acid
-
TJORNELUND, J., HANSEN, S. H. and CORNETT, C., 1989, New metabolites of the drug 5-aminosalicylic acid, I: N-b-D-glucopyranosyl-5-aminosalicylic acid. Xenobiotica, 19, 891-899.
-
(1989)
Xenobiotica
, vol.19
, pp. 891-899
-
-
Tjornelund, J.1
Hansen, S.H.2
Cornett, C.3
-
30
-
-
0034109201
-
Acute metobromuron poisoning with severe methaemoglobinemia, identification of four metabolites in plasma and urine by LC-DAD, LC-ESI-MS and LC-ESI-MS-MS
-
TURCANT, A., CAILLEUX, A., LE BOUIL, A., ALLAIN, P., HARRY, P. and RENAULT, A., 2000, Acute metobromuron poisoning with severe methaemoglobinemia, identification of four metabolites in plasma and urine by LC-DAD, LC-ESI-MS and LC-ESI-MS-MS. Journal of Analytical Toxicology, 24, 157-163.
-
(2000)
Journal of Analytical Toxicology
, vol.24
, pp. 157-163
-
-
Turcant, A.1
Cailleux, A.2
Le Bouil, A.3
Allain, P.4
Harry, P.5
Renault, A.6
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