Quantitative structure-metabolism relationships (QSMR) using computational chemistry: Pattern recognition analysis and statistical prediction of phase II conjugation reactions of substituted benzoic acids in the rat

Xenobiotica

Volumn 29, Issue 1, 1999, Pages 27-42

  Cupid, B C ^a,b,d   Holmes, E ^a   Wilson, I D ^b,d   Lindon, J C ^a   Nicholson, J K ^a,c  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c Sir Alexander Fleming Building   (United Kingdom)

^d UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID; GLUCURONIDE; GLYCINE;

ARTICLE; CALCULATION; DRUG CONJUGATION; DRUG METABOLISM; PATTERN RECOGNITION; PHYSICAL CHEMISTRY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL ANALYSIS; URINARY EXCRETION;

ANIMALS; BENZOIC ACIDS; COMPUTER SIMULATION; LINEAR MODELS; MODELS, BIOLOGICAL; MODELS, STATISTICAL; PATTERN RECOGNITION, AUTOMATED; RATS; REGRESSION ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032970618     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982599238795     Document Type: Article

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