High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: Application to the metabolites of 4-bromoaniline

Analyst

Volumn 125, Issue 2, 2000, Pages 235-236

  Nicholson, Jeremy K ^a   Lindon, John C ^a   Scarfe, Graeme ^a   Wilson, Ian D ^b   Abou Shakra, Fadi ^c   Castro Perez, Jose ^c   Eaton, Andrew ^c   Preece, Steve ^c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c MICROMASS UK LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 BROMOANILINE; ANILINE DERIVATIVE; DRUG METABOLITE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; BODY FLUID; DRUG METABOLISM; EXCRETION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METHODOLOGY; NONHUMAN; QUANTITATIVE ASSAY; RAT; URINE;

EID: 0033995198     PISSN: 00032654     EISSN: None     Source Type: Journal    
DOI: 10.1039/a909494f     Document Type: Article

References (6)

1. 1 G. B. Scarfe, B. Wright, E. Clayton, S. Taylor, I. D. Wilson, J. C. Lindon and J. K. Nicholson, Xenobiotica, 1999, 29, 77.
2. 2 G. B. Scarfe, J. C. Lindon, J. K. Nicholson, B. Wright, E. Clayton and I. D. Wilson, Drug Metab. Dispos., 1999, 27, 1171.
3. 3 K. Sutton and J. A. Caruso, J. Chromatogr., A, 1999, 856, 243.
4. 4 K. T. Suzuki and M. Itoh, J. Chromatogr., B, 1997, 692, 15.
5. 5 K. T. Suzuki, S. Yoneda, M. Itoh and M. Ohmichi, J. Chromatogr., B, 1995, 670, 63.
6. 6 G. Scarfe, PhD Thesis, Imperial College, University of London, 1999.