Role of the nitric-oxide synthase isoforms during morphine-induced hyperthermia in rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 307, Issue 1, 2003, Pages 219-222

  Benamar, Khalid ^a   Yondorf, Menachem Z ^a   Kon, David ^a   Geller, Ellen B ^a   Adler, Martin W ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 NITROINDAZOLE; AMINOGUANIDINE; MORPHINE; N(G) NITROARGININE METHYL ESTER; N5 (1 IMINOETHYL)ORNITHINE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE ISOFORM; ORNITHINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; HYPERTHERMIA; NONHUMAN; PRIORITY JOURNAL; RAT; TELEMETRY;

ANIMALS; BODY TEMPERATURE; DRUG INTERACTIONS; ENZYME INHIBITORS; FEVER; GUANIDINES; INDAZOLES; INFUSIONS, PARENTERAL; ISOENZYMES; MALE; MORPHINE; NITRIC OXIDE SYNTHASE; ORNITHINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0141519435     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.053181     Document Type: Article

References (38)

1. Adler MW and Geller EB (1993) Physiological functions of opioids: temperature regulation, in Handbook of Experimental Pharmacology, Vol. 104/II, Opioids II (Herz A, Akil H, and Simon EJ eds) pp 205-238, Springer-Verlag, Berlin, Germany.
2. Almeida MC and Branco LGS (2001) Role of nitric oxide in insulin-induced hypothermia in rats. Brain Res Bull 54:49-53.
3. G -Monomethyl-L-arginine co-injection attenuates the thermogenic and hyperthermic effects of E2 prostaglandin microinjection into the anterior hypothalamic preoptic area in rats. Brain Res 556:157-160.
4. Barna M, Komatsu T, and Reiss CS (1996) Activation oftype III nitric oxide synthase in astrocytes following a neurotropic viral infection. Virology 223:331-343.
5. Benamar K, Geller EB, and Adler MW (2002) Effect of a μ-opioid receptor-selective antagonist on interleukin-6 fever. Life Sci 70:2139-2145.
6. Benamar K, Xin L, Geller EB, and Adler MW (2000) Blockade of lipopolysaccharide-induced fever by a μ-opioid receptor-selective antagonist in rats. Eur J Pharmacol 401:161-165.
7. Benamar K, Xin L, Geller EB, and Adler MW (2001) Effect of central and peripheral administration of a nitric oxide synthase inhibitor on morphine hyperthermia in rats. Brain Res 894:266-273.
8. Branco LG, Carnio EC, and Barros RC (1997) Role of the nitric oxide pathway in hypoxia-induced hypothermia of rats. Am J Physiol 273:R967-R971.
9. Breder CD and Saper CB (1996) Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide. Brain Res 713:64-69.
10. Bredt DS and Snyder SH (1992) Nitric oxide, a novel neuronal messenger. Neuron 8:3-11.
11. Gath I, Benamar K, Jurat G, Roth J, Simon E, and Schmid HA (1999) Expression of nitric oxide synthase (NOS) isoforms in rat brain during lipopolysaccharide-induced fever. Eur J Physiol 437S:R143.
12. Geller EB, Hawk C, Tallarida RJ, and Adler MW (1982) Postulated thermoregulatory roles for different opiate receptors in rats. Life Sci 31:2241-2244.
13. Gerstberger R (1999) Nitric oxide and body temperature control. News Physiol Sci 14:30-36.
14. Gourine AV (1995) Pharmacological evidence that nitric oxide can act as an endogenous antipyretic factor in endotoxin-induced fever in rabbits. Gen Pharmacol 26:835-841.
15. Handler CM, Geller EB, and Adler MW (1992) Effect of mu-, kappa-, and delta-selective opioid agonists on thermoregulation in the rat. Pharmacol Biochem Behav 43:1209-1216.
16. Lin JH and Lin MT (1996) Nitric oxide synthase-cyclo-oxygenase pathway in organum vasculosum laminae terminalis: possible role in pyrogenic fever in rabbits, Br J Pharmacol 118:179-185.
17. Lopez-Figueroa MO, Day HE, Akil H, and Watson SJ (1998) Nitric oxide in the stress axis. Histol Histopathol 13:1243-1252.
18. Lowenstein CJ, Glatt CS, Bredt DS, and Snyder SH (1992) Cloned and expressed macrophage nitric oxide synthase contrasts with brain enzyme. Proc Natl Acad Sci USA 89:6711-6715.
19. MacKenzie GM, Rose S, Bland-Ward PA, Moore PK, Jenner P, and Marsden CD (1994) Time course of inhibition of brain nitric oxide synthase by 7-nitro indazole. Neuroreport 5:1993-1996.
20. Mansour A, Khachaturian H, Lewis ME, Akil H, and Watson SJ (1987) Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J Neurosci 7:2445-2464.
21. 2- or lipopolysaccharide-induced fever. Ann NY Acad Sci 813:272-280.
22. Moncada S, Palmer RMJ, and Higgs EA (1991) Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43:109-142.
23. Mustafa SB and Olson MS (1998) Expression of nitric-oxide synthase in rat Kupffer cells is regulated by cAMP. J Biol Chem 273:5073-5080.
24. Perotti CA, Nogueira MS, Antunes-Rodrigues J, and Carnio EC (1999) Effects of a neuronal nitric oxide synthase inhibitor on lipopolysaccharide-induced fever. Braz J Med Biol Res 32:1381-1387.
25. Roth J, Störr B, Goldbach J-M, Voigt K, and Zeisberger E (1999) Dose-dependent attenuation of lipopolysaccharide-fever by inhibitors of inducible nitric oxidesynthase in guinea pigs. Eur J Pharmacol 383:177-187.
26. Roth J, Störr B, Voigt K, and Zeisberger E (1998) Inhibition of nitric oxide synthase results in a suppression of interleukin-1β-induced fever in rats. Life Sci 62:PL345-PL350.
27. Salmi P, Kela J, Arvidsson U, and Wahlestedt C (2003) Functional interaction between δ- and μ-opioid receptors in rat thermoregulation. Eur J Pharmacol 458:101-106.
28. Sanches DB, Steiner AA, and Branco LGS (2002) Involvement of neuronal nitric oxide synthase in restraint stress-induced fever in rats. Physiol Behav 75:261-266.
29. Scammell TE, Elmquist JK, and Saper CB (1996) Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. Am J Physiol 271:R333-R338.
30. Sehic E, Gerstberger R, and Blatteis CM (1997) The effect of intravenous lipopolysaccharide on NADPH-diaphorase staining (nitric oxide synthase activity) in the organum vasculosum laminae terminalis of guinea pigs. Ann NY Acad Sci 813:383-391.
31. Sharma HS, Drieu K, Alm P, and Westman J (1999) Upregulation of neuronal nitric oxide synthase, edema and cell injury following heat stress are reduced by pre-treatment with EGB-761 in the rat. J Therm Biol 24:439-445.
32. Spencer RL, Hruby VJ, and Burks TF (1988) Body temperature response profiles for selective mu, delta and kappa opioid agonists in restrained and unrestrained rats. J Pharmacol Exp Ther 246:92-101.
33. Steiner AA, Antunes-Rodrigues J, McCann SM, and Branco LG (2002) Antipyretic role of the NO-cGMP preoptic region of the rat brain. Am J Physiol Regul Integr Comp Physiol 282:R584-R593.
34. Steiner AA, Carnio EC, Antunes-Rodrigues J, and Branco LG (1998) Role of nitric oxide in systemic vasopressin-induced hypothermia. Am J Physiol 275:R937-R941.
35. VanDam AM, Bauer J, Man-A-Hing WK, Marquette C, Tilders FJ, and Berkenbosch F (1995) Appearance of inducible nitric oxide synthase in the rat central nervous system after rabies virus infection and during experimental allergic encephalomyelitis but not after peripheral administration of endotoxin. J Neurosci Res 40:251-260.
36. Xie QW, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Ding A, Troso T, and Nathan C (1992) Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science (Wash DC) 256:225-228.
37. Xin L, Zhao SF, Geller EB, McCafferty MR, Sterling GH, and Adler MW (1997) Involvement of β-endorphin in the preoptic anterior hypothalamus during interleukin-1β-induced fever in rats. Ann NY Acad Sci 813:324-326.
38. Yang WW and Krukoff TL (2000) Nitric oxide regulates body temperature, neuronal activation and interleukin-1β gene expression in the hypothalamic paraventricular nucleus in response to immune stress. Neuropharmacology 39:2075-2089.