Effects of a neuronal nitric oxide synthase inhibitor on lipopolysaccharide-induced fever

Brazilian Journal of Medical and Biological Research

Volumn 32, Issue 11, 1999, Pages 1381-1387

  Perotti, C A A ^a   Nogueira, M S ^a   Antunes Rodrigues, J ^a   Carnio E C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

7 Nitroindazole; Body temperature; L NAME; LPS; Nitric oxide

Indexed keywords

7 NITROINDAZOLE; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; BODY TEMPERATURE; CONFERENCE PAPER; DRUG EFFECT; ENZYME INHIBITION; FEVER; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; RAT; THERMOREGULATION;

EID: 0032805704     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X1999001100008     Document Type: Conference Paper

References (30)

1. Nagashima T, Ohinata H & Kuroshima A (1994). Involvement of nitric oxide in noradrenaline-induced increase n blood flow through brown adipose tissue. Life Sciences, 54: 17-25.
2. Bachmann S, Bosse HM & Mundel P (1995). Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney. American Journal of Physiology, 268 (Renal, Fluid and Electrolyte Physiology, 37): F885-F898.
3. Bachmann S, Bosse HM & Mundel P (1995). Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney. American Journal of Physiology, 268 (Renal, Fluid and Electrolyte Physiology, 37): F885-F898.
4. Dominiczak AF & Bohr DF (1995). Nitric oxide and its putative role in hypertension. Hypertension, 25: 1202-1210.
5. Schmidt HHHW, Gagne GD, Nakane M, Pollock JS, Miller MF & Murad F (1992). Mapping of nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrergic signal transduction. Journal of Histochemistry and Cytochemistry, 40: 1439-1456.
6. Ignarro LJ, Buga GM, Wood KS, Byrns RE & Chaudhuri G (1987). Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proceedings of the National Academy of Sciences, USA, 84: 9265-9269.
7. Palmer RMJ, Ashton DS & Moncada S (1988). Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature, 333: 664-666.
8. Rivier C & Shen G (1994). In the rat, endogenous nitric oxide modulates the response of the hypothalamic-pituitary-adrenal axis to interleukin-1ß, vasopressin, and oxytocin. Journal of Neuroscience, 14: 1985-1993.
9. Kluger MJ (1991). Fever: role of pyrogens and cryogens. Physiological Reviews, 71: 93-127.
10. Tiao G, Raferty J, Ogle C, Fischer J & Ohasselgren P (1994). Detrimental effect of nitric oxide synthase inhibition during endotoxemia may be caused by high levels of tumor necrosis factor and interleukin-6. Surgery, 116: 332-338.
11. Scammell TE, Elmquist JK & Saper CB (1996). Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. American Journal of Physiology, 271 (Regulatory, Integrative and Comparative Physiology, 40): R333-R338.
12. Scammell TE, Elmquist JK & Saper CB (1996). Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. American Journal of Physiology, 271 (Regulatory, Integrative and Comparative Physiology, 40): R333-R338.
13. Moore PK, Babbedge RC, Wallace P, Gaffen ZA & Hart SL (1993). 7-N troindazole, an inhib tor of nitric oxide synthase exhibits antinociceptive activity in mouse without increasing blood pressure. British Journal of Pharmacology, 108: 296-297.
14. Moore PK, Wallace P, Gaffen Z, Hart SL & Babbedge RC (1993). Characterization of the novel nitric oxide synthase inhibitor 7-nitro-indazole and related indazoles: anti-nociceptive and cardiovascular effects. British Journal of Pharmacology, 110: 219-224.
15. Mackenzie GM, Rose S, Blande-Ward PA, Moore PK, Jenner P & Marsden CD (1994). Time course of inhibition of brain nitric oxide synthase by 7-nitro-indazole. NeuroReport, 5: 1993-1996.
16. Moncada S, Palmer RMJ & Higgs EA (1991). Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacological Reviews, 43: 109-142.
17. Rees D, Palmer R, Schultz R, Hodson H & Moncada S (1990). Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. British Journal of Pharmacology, 101: 746-752.
18. Foster DD & Frydman ML (1979). Tissue distribution of cold-induced thermogenesis in conscious warm or cold acclimated rats reevaluated from changes in tissue blood flow: the dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis. Canadian Journal of Physiology and Pharmacology, 57: 257-270.
19. Kajecar R, Moore PK & Brain SD (1995). Essential role for nitric oxide in neurogenic inflammation in rat cutaneous microcirculat on. Evidence for an endothelium-independent mechanism. Circulation Research, 76: 441-447.
20. Kobzik L, Reid MB, Bredt DS & Stamler JS (1994). Nitric oxide in skeletal muscle. Nature, 372 546-548.
21. Kobzik KL, Stringer JL, Balligand M, Reid B & Stamler JS (1995) Endothelial type nitric oxide synthase in skeletal muscle fibers; mitochondrial relationships. Biochemical and Biophysical Research Communications, 211: 375-381.
22. Balon TW & Nadler JL (1994). Nitric oxide is present from incubated skeletal muscle preparations. Journal of Applied Physiology, 77: 2519-2521.
23. Morrison RJ, Miller CC & Reid MB (1996). Nitric oxide effects on shortening velocity and power production in the rat diaphragm. Journal of Applied Physiology, 80: 1065-1069.
24. Murrant CL, Woodley NE & Barclay JK (1994). Effect of introprusside and endothelium-derived products on slow-twitch skeletal muscle function in vitro. Canadian Journal of Physiology and Pharmacology, 72: 1089-1093.
25. Balon TW & Nadler JL (1997). Evidence that nitric oxide nereases glucose transport in skeletal muscle. Journal of Applied Physiology, 82: 359-363.
26. De Luca B, Monda M & Sullo A (1995). Changes in eat ng behavior and thermoregulation activity following inhibition of nitric oxide formation. American Journal of Physiology, 268 (Regulatory, Integrative and Comparative Physiology, 371: R1533-R1538.
27. De Luca B, Monda M & Sullo A (1995). Changes in eat ng behavior and thermoregulation activity following inhibition of nitric oxide formation. American Journal of Physiology, 268 (Regulatory, Integrative and Comparative Physiology, 371: R1533-R1538.
28. Branco LGS, Cãrnio EC & Barros RCH (1997). Role of the nitric oxide pathway in hypoxia-induced hypothermia of rats. American Journal of Physiology, 273 (Regulatory, Integrative and Comparative Physiology, 42): R967-R971.
29. Branco LGS, Cãrnio EC & Barros RCH (1997). Role of the nitric oxide pathway in hypoxia-induced hypothermia of rats. American Journal of Physiology, 273 (Regulatory, Integrative and Comparative Physiology, 42): R967-R971.
30. Yamamoto T, Kimura T, Ota K, Sholi M, Inoue M, Otha M, Sato K, Funyu T & Abe K (1994). Effects of a nitric oxide synthase inhibition on vasopressin and atrial natriuretic hormone release, thermogenesis and cardiovascular functions in response to interleukin-1ß in rats. Tohoku Journal of Experimental Medicine, 174: 59-69.