-
2
-
-
0141747593
-
-
Fischer Nobel Prize
-
Fischer Nobel Prize: http://www.nobel.se/chemistry/laureates/1902/
-
-
-
-
3
-
-
84892166712
-
Einfluss der Configuration auf die Wirkung den Enzyme
-
Fischer E. Einfluss der Configuration auf die Wirkung den Enzyme. Ber. Dtsch. Chem. Ges. 1894: 27: 2985-2993.
-
(1894)
Ber. Dtsch. Chem. Ges.
, vol.27
, pp. 2985-2993
-
-
Fischer, E.1
-
4
-
-
85047678643
-
Ueber Bau und Gruppierung der Eiweisskörper
-
Hofmeister F. Ueber Bau und Gruppierung der Eiweisskörper. Ergeb. Physiol. 1902; 1: 759-802.
-
(1902)
Ergeb. Physiol.
, vol.1
, pp. 759-802
-
-
Hofmeister, F.1
-
5
-
-
0009344903
-
Ueber die Hydrolyse der Proteinstoffe
-
(Hofmeister had presented his famous plenary lecture on protein structure in the morning of the 74th meeting of the Society of German Scientists and Physicians (1902, Karlsbad). That same afternoon, Fischer read his paper on the isolation of amino acids and peptides from protein hydrosylates, and suggested the coupling of amino acids in proteins). Adapted from
-
Fischer E. Ueber die Hydrolyse der Proteinstoffe. Chemiker Zeitung 1902; 26: 939-940. (Hofmeister had presented his famous plenary lecture on protein structure in the morning of the 74th meeting of the Society of German Scientists and Physicians (1902, Karlsbad). That same afternoon, Fischer read his paper on the isolation of amino acids and peptides from protein hydrosylates, and suggested the coupling of amino acids in proteins). Adapted from: http://www.pepnet.com/fischerbio.html
-
(1902)
Chemiker Zeitung
, vol.26
, pp. 939-940
-
-
Fischer, E.1
-
6
-
-
0141859162
-
Synthese von Polypeptiden, IV. Derivate des Phenylalanins
-
Fischer E. Synthese von Polypeptiden, IV. Derivate des Phenylalanins. Ber. dtsch. chem. Ges. 1904; 37: 3062-3071.
-
(1904)
Ber. Dtsch. Chem. Ges.
, vol.37
, pp. 3062-3071
-
-
Fischer, E.1
-
7
-
-
84946388015
-
Synthese von Polypeptiden, XVII
-
Fischer E. Synthese von Polypeptiden, XVII. Ber. dtsch. chem. Ges. 1907; 40: 1754-1767.
-
(1907)
Ber. Dtsch. Chem. Ges.
, vol.40
, pp. 1754-1767
-
-
Fischer, E.1
-
8
-
-
0033791223
-
Synthesis of native proteins by chemical ligation
-
Dawson PE, Kent SBH. Synthesis of native proteins by chemical ligation. Ann. Rev. Biochem. 2000; 69: 925-962.
-
(2000)
Ann. Rev. Biochem.
, vol.69
, pp. 925-962
-
-
Dawson, P.E.1
Kent, S.B.H.2
-
9
-
-
0024412506
-
Crystal structure of synthetic HIV-1 protease: Conserved fold in retroviral proteases
-
Wlodawer A, Miller M, Jaskolski M, Sathyanarayana BK, Baldwin E, Weber IT, Selk LM, Clawson L, Schneider J, Kent SBH. Crystal structure of synthetic HIV-1 protease: conserved fold in retroviral proteases. Science 1989; 245: 616-621.
-
(1989)
Science
, vol.245
, pp. 616-621
-
-
Wlodawer, A.1
Miller, M.2
Jaskolski, M.3
Sathyanarayana, B.K.4
Baldwin, E.5
Weber, I.T.6
Selk, L.M.7
Clawson, L.8
Schneider, J.9
Kent, S.B.H.10
-
10
-
-
0024344021
-
Structure of a complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 Å resolution
-
Miller M, Schneider J, Sathyanarayana BK, Toth MV, Marshall GR, Clawson L, Selk L, Kent SBH, Wlodawer A. Structure of a complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 Å resolution. Science 1989: 246: 1149-1152.
-
(1989)
Science
, vol.246
, pp. 1149-1152
-
-
Miller, M.1
Schneider, J.2
Sathyanarayana, B.K.3
Toth, M.V.4
Marshall, G.R.5
Clawson, L.6
Selk, L.7
Kent, S.B.H.8
Wlodawer, A.9
-
11
-
-
0025225682
-
X-ray crystallographic structure of a complex between synthetic HIV-1 protease and a substrate-based hydroxyethylamine inhibitor
-
Swain AL, Miller M, Green J, Rich DH, Schneider J, Kent SBH, Wlodawer A. X-ray crystallographic structure of a complex between synthetic HIV-1 protease and a substrate-based hydroxyethylamine inhibitor. Proc. Natl Acad. Sci. USA 1990; 87: 8805-8809.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8805-8809
-
-
Swain, A.L.1
Miller, M.2
Green, J.3
Rich, D.H.4
Schneider, J.5
Kent, S.B.H.6
Wlodawer, A.7
-
12
-
-
0025829331
-
Structure at 2.5 Å resolution of chemically synthesized HIV-1 protease complexed with a hydroxyethylene-based inhibitor
-
Jaskolski M, Tomasselli AG, Sawyer TK, Staples DG, Heinrikson RL, Schneider J, Kent SBH, Wlodawer A. Structure at 2.5 Å resolution of chemically synthesized HIV-1 protease complexed with a hydroxyethylene-based inhibitor. Biochemistry 1991; 30: 1600-1609.
-
(1991)
Biochemistry
, vol.30
, pp. 1600-1609
-
-
Jaskolski, M.1
Tomasselli, A.G.2
Sawyer, T.K.3
Staples, D.G.4
Heinrikson, R.L.5
Schneider, J.6
Kent, S.B.H.7
Wlodawer, A.8
-
15
-
-
0025108755
-
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution
-
Fitzgerald PMD, Mckeever BM, Vanmiddlesworth JF, Springer JP, Heimbach JC, Leu C-T, Herber WK, Dixon RAF, Darke PL. Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution. J. Biol. Chem. 1990; 265: 14 209.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 14209
-
-
Fitzgerald, P.M.D.1
Mckeever, B.M.2
Vanmiddlesworth, J.F.3
Springer, J.P.4
Heimbach, J.C.5
Leu, C.-T.6
Herber, W.K.7
Dixon, R.A.F.8
Darke, P.L.9
-
16
-
-
0015522891
-
The carboxylate ion in the active center of pepsin
-
Hartsuck JA, Tang J. The carboxylate ion in the active center of pepsin. J. Biol. Chem. 1972; 247: 2575-2580.
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 2575-2580
-
-
Hartsuck, J.A.1
Tang, J.2
-
17
-
-
0027137058
-
Catalytic contribution of flap-substrate hydrogen bonds in HIV-1 protease explored by chemical synthesis
-
Baca M, Kent SBH. Catalytic contribution of flap-substrate hydrogen bonds in HIV-1 protease explored by chemical synthesis. Proc. Natl Acad. Sci. US 1993; 90: 11 638-11 642.
-
(1993)
Proc. Natl. Acad. Sci. US
, vol.90
, pp. 11638-11642
-
-
Baca, M.1
Kent, S.B.H.2
-
18
-
-
0025085668
-
Characterization of an active single polypeptide form of the human immunodeficiency virus type 1 protease
-
DiIanni CL, Davis LJ, Holloway MK, Herber WK, Darke PL, Kohl NE, Dixon RA. Characterization of an active single polypeptide form of the human immunodeficiency virus type 1 protease. J. Biol. Chem. 1990,; 265: 17 348-17 354.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 17348-17354
-
-
DiIanni, C.L.1
Davis, L.J.2
Holloway, M.K.3
Herber, W.K.4
Darke, P.L.5
Kohl, N.E.6
Dixon, R.A.7
-
19
-
-
0025641617
-
Stability and activity of human immunodeficiency virus protease: Comparison of the natural dimer with a homologous, single-chain tethered dimer
-
Cheng YE, Yin FH, Foundling SF, Blomstrom S, Kettner CA. Stability and Activity of Human Immunodeficiency Virus Protease: Comparison of the Natural Dimer with a Homologous, Single-Chain Tethered Dimer. Proc. National Academy Sciences USA 1990; 87: 9660-9664.
-
(1990)
Proc. National Academy Sciences USA
, vol.87
, pp. 9660-9664
-
-
Cheng, Y.E.1
Yin, F.H.2
Foundling, S.F.3
Blomstrom, S.4
Kettner, C.A.5
-
20
-
-
0031042369
-
Activity of tethered human immunodeficiency virus 1 protease containing mutations in the flap region of one subunit
-
Tozer J, Yin FH, Cheng YS, Bagossi P, Weber IT, Harrison RW, Oroszlan S. Activity of tethered human immunodeficiency virus 1 protease containing mutations in the flap region of one subunit. Eur. J. Biochem. 1997; 244: 235-241.
-
(1997)
Eur. J. Biochem.
, vol.244
, pp. 235-241
-
-
Tozer, J.1
Yin, F.H.2
Cheng, Y.S.3
Bagossi, P.4
Weber, I.T.5
Harrison, R.W.6
Oroszlan, S.7
-
21
-
-
0028810342
-
Chemical ligation of cysteine-containing peptides: Synthesis of a 22 kDa tethered dimer of HIV-1 protease
-
Baca M, Muir TW, Schnölzer M, Kent SBH. Chemical ligation of cysteine-containing peptides: synthesis of a 22 kDa tethered dimer of HIV-1 protease. J. Am. Chem. Soc. 1995: 117: 1881-1887.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 1881-1887
-
-
Baca, M.1
Muir, T.W.2
Schnölzer, M.3
Kent, S.B.H.4
-
22
-
-
0034711433
-
Protein backbone engineering through total chemical synthesis: New insight into the mechanism of HIV-1 protease catalysis
-
Baca M, Kent SBH. Protein backbone engineering through total chemical synthesis: new insight into the mechanism of HIV-1 protease catalysis. Tetrahedron 2000; 56: 9503-9513.
-
(2000)
Tetrahedron
, vol.56
, pp. 9503-9513
-
-
Baca, M.1
Kent, S.B.H.2
-
23
-
-
0018133234
-
Synthesis and biological activity of two disulphide bond isomers of human insulin: [A7-A11,A6-B7-cystine]- and [A6-A7,A11-B7-cystine]insulin (human)
-
Sieber P, Eisler K, Kamber B, Riniker B, Rittel W, et al. Synthesis and biological activity of two disulphide bond isomers of human insulin: [A7-A11,A6-B7-cystine]- and [A6-A7,A11-B7-cystine]insulin (human). Hoppe Selyler's Z. Physiol. Chem. 1978; 359: 113-123.
-
(1978)
Hoppe Selyler's Z. Physiol. Chem.
, vol.359
, pp. 113-123
-
-
Sieber, P.1
Eisler, K.2
Kamber, B.3
Riniker, B.4
Rittel, W.5
-
24
-
-
0022000347
-
Studies on peptides. CXXVII. Synthesis of a tripentacontapeptide with epidermal growth factor activity
-
Akaji K, Fujii N, Yajima H, Hayashi K, Mizuta K, et al. Studies on peptides. CXXVII. Synthesis of a tripentacontapeptide with epidermal growth factor activity. Chem. Pharm. Bull. 1985; 33: 184-201.
-
(1985)
Chem. Pharm. Bull.
, vol.33
, pp. 184-201
-
-
Akaji, K.1
Fujii, N.2
Yajima, H.3
Hayashi, K.4
Mizuta, K.5
-
25
-
-
0027238026
-
The structure of a centrosymmetric protein crystal
-
Zawadzke LE, Berg JM. The structure of a centrosymmetric protein crystal. Proteins 1993; 16: 301-305.
-
(1993)
Proteins
, vol.16
, pp. 301-305
-
-
Zawadzke, L.E.1
Berg, J.M.2
-
26
-
-
0029677674
-
Solution synthesis of human midkine, a novel heparin-binding neurotrophic factor consisting of 121 amino acid residues with five disulphide bonds
-
Inui T, Bodi J, Kubo S, Hishio H, Kimura T, Kojima S, Maruta H, Muramatsu T, Sakakibara S. Solution synthesis of human midkine, a novel heparin-binding neurotrophic factor consisting of 121 amino acid residues with five disulphide bonds. J. Peptide Sci. 1996; 2: 28-39.
-
(1996)
J. Peptide Sci.
, vol.2
, pp. 28-39
-
-
Inui, T.1
Bodi, J.2
Kubo, S.3
Hishio, H.4
Kimura, T.5
Kojima, S.6
Maruta, H.7
Muramatsu, T.8
Sakakibara, S.9
-
27
-
-
0001462324
-
Development of a linker with an enhanced stability for the preparation of peptide thioesters and its application to the synthesis of a stable-isotope-labeled hu-type DNA-binding protein
-
Hojo H, Kwon Y, Kakuta Y, Tsuda S, Tanaka I, Hikichi K, Aimoto S. Development of a linker with an enhanced stability for the preparation of peptide thioesters and its application to the synthesis of a stable-isotope-labeled hu-type DNA-binding protein. Bull. Chem. Soc. Jpn. 1993; 66: 2700-2706.
-
(1993)
Bull. Chem. Soc. Jpn.
, vol.66
, pp. 2700-2706
-
-
Hojo, H.1
Kwon, Y.2
Kakuta, Y.3
Tsuda, S.4
Tanaka, I.5
Hikichi, K.6
Aimoto, S.7
-
28
-
-
0024421799
-
Chemical synthesis in protein engineering: Total synthesis, purification, and covalent structural characterization of a mitogenic protein, human transforming growth factor-α
-
Woo DD-L, Clarke-Lewis I, Chait BT, Kent SBH. Chemical synthesis in protein engineering: total synthesis, purification, and covalent structural characterization of a mitogenic protein, human transforming growth factor-α. Protein Eng 1989; 3: 29-37.
-
(1989)
Protein Eng.
, vol.3
, pp. 29-37
-
-
Woo, D.D.-L.1
Clarke-Lewis, I.2
Chait, B.T.3
Kent, S.B.H.4
-
29
-
-
0026525457
-
Constructing proteins by dovetailing unprotected synthetic peptides: Backbone engineered HIV protease
-
Schnölzer M, Kent S. Constructing proteins by dovetailing unprotected synthetic peptides: backbone engineered HIV protease. Science 1992; 256: 221-225.
-
(1992)
Science
, vol.256
, pp. 221-225
-
-
Schnölzer, M.1
Kent, S.2
-
30
-
-
0040555246
-
Synthesis of proteins by chemical ligation of unprotected peptide segments: Mirror-image enzyme molecules, D- and L-HIV protease analogues
-
Angeletti R (ed.). Academic Press: New York
-
Milton R. deL, Milton S, Schnölzer M, Kent SBH. Synthesis of proteins by chemical ligation of unprotected peptide segments: mirror-image enzyme molecules, D- & L-HIV protease analogues. In Techniques in Protein Chemistry IV, Angeletti R (ed.). Academic Press: New York, 1993; 257-267.
-
(1993)
Techniques in Protein Chemistry IV
, pp. 257-267
-
-
Milton, R.deL.1
Milton, S.2
Schnölzer, M.3
Kent, S.B.H.4
-
31
-
-
0001702244
-
Probing the structural basis of the catalytic activity of HIV-1 protease through total chemical protein synthesis
-
Miller M, Baca M, Rao JKM, Kent S. Probing the structural basis of the catalytic activity of HIV-1 protease through total chemical protein synthesis. J. Molec. Structure (THEOCHEM) 1998; 423: 137-152.
-
(1998)
J. Molec. Structure (THEOCHEM)
, vol.423
, pp. 137-152
-
-
Miller, M.1
Baca, M.2
Rao, J.K.M.3
Kent, S.4
-
32
-
-
0001087039
-
Computational studies of the aminolysis of oxoesters and thioesters in aqueous solution
-
Yang W, Drueckhammer DG. Computational studies of the aminolysis of oxoesters and thioesters in aqueous solution. Organic Lett. 2000; 2: 4133-4136.
-
(2000)
Organic Lett.
, vol.2
, pp. 4133-4136
-
-
Yang, W.1
Drueckhammer, D.G.2
-
33
-
-
84939246733
-
Uber peptidsynthesen. 8. Bildung von s-haltigen peptiden durch intramolekulare wanderung von aminoacylresten
-
Wieland Th, et al. Uber peptidsynthesen. 8. Bildung von s-haltigen peptiden durch intramolekulare wanderung von aminoacylresten. Liebig's Annalen der Chemie 1953; 583: 129-149.
-
(1953)
Liebig's Annalen Der Chemie
, vol.583
, pp. 129-149
-
-
Wieland, Th.1
-
35
-
-
0030822919
-
Total chemical synthesis of enzymatically active human type II secretory phospholipase A2
-
Hackeng TM, Mounier CM, Bon C, Dawson PE, Griffin JH, Kent SBH. Total chemical synthesis of enzymatically active human type II secretory phospholipase A2. Proc. Natl Acad. Sci. USA 1997; 94: 7845-7850.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7845-7850
-
-
Hackeng, T.M.1
Mounier, C.M.2
Bon, C.3
Dawson, P.E.4
Griffin, J.H.5
Kent, S.B.H.6
-
36
-
-
0026706930
-
Weighing naked proteins: Practical, high-accuracy mass measurement of peptides and proteins
-
Chait BT, Kent SBH. Weighing naked proteins: practical, high-accuracy mass measurement of peptides and proteins. Science 1992; 257: 1885-1894.
-
(1992)
Science
, vol.257
, pp. 1885-1894
-
-
Chait, B.T.1
Kent, S.B.H.2
-
37
-
-
0030973396
-
Modulation of reactivity in native chemical ligation through the use of thiol additives
-
Dawson PE, Churchill M, Ghadiri MR, Kent SBH. Modulation of reactivity in native chemical ligation through the use of thiol additives. J. Am. Chem. Soc. 1997; 119: 4325-4329.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 4325-4329
-
-
Dawson, P.E.1
Churchill, M.2
Ghadiri, M.R.3
Kent, S.B.H.4
-
38
-
-
0033621158
-
Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology
-
Hackeng TM, Griffin JH, Dawson PE. Protein synthesis by native chemical ligation: expanded scope by using straightforward methodology. Proc. Natl Acad. Sci. USA 1999; 96: 10 068-10 073.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10068-10073
-
-
Hackeng, T.M.1
Griffin, J.H.2
Dawson, P.E.3
-
39
-
-
0033168207
-
Probing intermolecular backbone H-bonding in serine-proteinase protein-inhibitor complexes
-
Lu W, Randal M, Kossiakoff A, Kent SBH. Probing intermolecular backbone H-bonding in serine-proteinase protein-inhibitor complexes. Chem. Biol. 1999; 6: 419-427.
-
(1999)
Chem. Biol.
, vol.6
, pp. 419-427
-
-
Lu, W.1
Randal, M.2
Kossiakoff, A.3
Kent, S.B.H.4
-
40
-
-
0037423148
-
Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein
-
Gerd GK, Chen S-Y, Mao F, Cressman S, Traviglia S, Shao H, Hunter C, Low D, Cagle N, Carnevali M, Gueriguian V, Keogh P, Porter H, Stratton SM, Con Wiedeke M, Wilken J, Tang J, Levy JJ, Miranda LP, Crnogorac M, Kalbag S, Botti P, Schindler-Horvath J, Savatski L, Adamson JW, Kung A, Kent SBH, Bradburne JA. Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein. Science 2003; 299: 884-887.
-
(2003)
Science
, vol.299
, pp. 884-887
-
-
Gerd, G.K.1
Chen, S.-Y.2
Mao, F.3
Cressman, S.4
Traviglia, S.5
Shao, H.6
Hunter, C.7
Low, D.8
Cagle, N.9
Carnevali, M.10
Gueriguian, V.11
Keogh, P.12
Porter, H.13
Stratton, S.M.14
Con Wiedeke, M.15
Wilken, J.16
Tang, J.17
Levy, J.J.18
Miranda, L.P.19
Crnogorac, M.20
Kalbag, S.21
Botti, P.22
Schindler-Horvath, J.23
Savatski, L.24
Adamson, J.W.25
Kung, A.26
Kent, S.B.H.27
Bradburne, J.A.28
more..
-
41
-
-
0030037155
-
Extending the applicability of native chemical ligation
-
Canne LE Bark SJ, Kent SBH. Extending the applicability of native chemical ligation. J. Am. Chem. Soc. 1996; 118: 5891-5896.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 5891-5896
-
-
Canne, L.E.1
Bark, S.J.2
Kent, S.B.H.3
-
42
-
-
0033657692
-
Nalpha-2-mercaptobenzylamine-assisted chemical ligation
-
Offer J, Dawson PE. Nalpha-2-mercaptobenzylamine-assisted chemical ligation. Org Lett. 2000; 2: 23-26.
-
(2000)
Org. Lett.
, vol.2
, pp. 23-26
-
-
Offer, J.1
Dawson, P.E.2
-
44
-
-
0035811061
-
Total synthesis of cytochrome b562 by native chemical ligation using a removable auxiliary
-
Low DW, Hill MG, Carrasco MR, Botti P, Kent SBH. Total synthesis of cytochrome b562 by native chemical ligation using a removable auxiliary. Proc. Natl Acad. Sci. USA 2001; 98: 6554-6559.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6554-6559
-
-
Low, D.W.1
Hill, M.G.2
Carrasco, M.R.3
Botti, P.4
Kent, S.B.H.5
-
45
-
-
0034643993
-
A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds
-
Saxon E, Armstrong JI, Bertozzi CR. A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds. Org. Lett. 2000; 2: 2141-2143.
-
(2000)
Org. Lett.
, vol.2
, pp. 2141-2143
-
-
Saxon, E.1
Armstrong, J.I.2
Bertozzi, C.R.3
-
46
-
-
0035843279
-
High-yielding Staudinger ligation of a phosphinothioester and azide to form a peptide
-
Nilsson BL, Kiessling LL, Raines RT. High-yielding Staudinger ligation of a phosphinothioester and azide to form a peptide. Org. Lett. 2001; 3: 9-12.
-
(2001)
Org. Lett.
, vol.3
, pp. 9-12
-
-
Nilsson, B.L.1
Kiessling, L.L.2
Raines, R.T.3
-
47
-
-
0001414449
-
Probing intermolecular main chain H-bonding in serine proteinase-protein inhibitor complexes: Chemical synthesis of a backbone-engineered turkey ovomucoid third domain
-
Lu W, Qasim MA, Laskowski M Jr., Kent SBH. Probing intermolecular main chain H-bonding in serine proteinase-protein inhibitor complexes: chemical synthesis of a backbone-engineered turkey ovomucoid third domain. Biochemistry 1997; 36: 673-679.
-
(1997)
Biochemistry
, vol.36
, pp. 673-679
-
-
Lu, W.1
Qasim, M.A.2
Laskowski M., Jr.3
Kent, S.B.H.4
-
48
-
-
0029140496
-
Total chemical synthesis of a unique transcription factor-related protein: cMyc-Max
-
Canne LE, Ferré-D'Amaré AR, Burley SK, Kent SBH. Total chemical synthesis of a unique transcription factor-related protein: cMyc-Max. J. Am. Chem. Soc. 1995; 117: 2998-3007.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 2998-3007
-
-
Canne, L.E.1
Ferré-D'Amaré, A.R.2
Burley, S.K.3
Kent, S.B.H.4
-
49
-
-
0026486811
-
"In situ" Neutralization protocols in Boc-chemistry solid phase peptide synthesis: Rapid, high yield assembly of difficult sequences
-
Schnolzer M, Alewood P, Alewood D, Kent SBH. "In situ" neutralization protocols in Boc-chemistry solid phase peptide synthesis: rapid, high yield assembly of difficult sequences. Int. J. Pept. Prot. Res. 1992: 40: 180-193.
-
(1992)
Int. J. Pept. Prot. Res.
, vol.40
, pp. 180-193
-
-
Schnolzer, M.1
Alewood, P.2
Alewood, D.3
Kent, S.B.H.4
-
50
-
-
0033615313
-
Chemical protein synthesis by solid phase ligation of unprotected peptide segments
-
Canne LE, Botti P, Simon RJ, Yijun Chen Y, Dennis EA, Kent SBH. Chemical protein synthesis by solid phase ligation of unprotected peptide segments. J. Am. Chem. Soc. 1999; 121: 8720-8727.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 8720-8727
-
-
Canne, L.E.1
Botti, P.2
Simon, R.J.3
Yijun Chen, Y.4
Dennis, E.A.5
Kent, S.B.H.6
-
51
-
-
0034674698
-
Protein synthesis by solid-phase chemical ligation using a safety catch linker
-
Brik A, Keinan E, Dawson PE. Protein synthesis by solid-phase chemical ligation using a safety catch linker. J. Org. Chem. 2000; 65: 3829-3835.
-
(2000)
J. Org. Chem.
, vol.65
, pp. 3829-3835
-
-
Brik, A.1
Keinan, E.2
Dawson, P.E.3
-
52
-
-
0037548053
-
Semisynthesis of proteins by expressed protein ligation
-
Tom W. Muir
-
Muir TW. Semisynthesis of proteins by expressed protein ligation. Tom W. Muir, Annu. Rev. Biochem. (2003) 72: 249-289.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 249-289
-
-
Muir, T.W.1
-
53
-
-
20744456789
-
Solid phase peptide synthesis. 1. Synthesis of a tetrapeptide
-
Merrifield RB. Solid phase peptide synthesis. 1. Synthesis of a tetrapeptide. J. Am. Chem. Soc. 1963; 85: 2149.
-
(1963)
J. Am. Chem. Soc.
, vol.85
, pp. 2149
-
-
Merrifield, R.B.1
-
54
-
-
0027213390
-
Structural engineering of HIV-1 protease with a β-turn mimic of fixed geometry
-
Baca M, Alewood P, Kent SBH. Structural engineering of HIV-1 protease with a β-turn mimic of fixed geometry. Protein Sci. 1993; 2: 1085-1091.
-
(1993)
Protein Sci.
, vol.2
, pp. 1085-1091
-
-
Baca, M.1
Alewood, P.2
Kent, S.B.H.3
-
55
-
-
0035793820
-
Chemical synthesis of lymphotactin: A glycosylated chemokine with a C-terminal mucin-like domain
-
Marcaurelle LA, Mizoue LS, Wilken J, Oldham L, Kent SB, Handel TM, Bertozzi CR. Chemical synthesis of lymphotactin: a glycosylated chemokine with a C-terminal mucin-like domain. Chemistry 2001; 7: 1129-1132.
-
(2001)
Chemistry
, vol.7
, pp. 1129-1132
-
-
Marcaurelle, L.A.1
Mizoue, L.S.2
Wilken, J.3
Oldham, L.4
Kent, S.B.5
Handel, T.M.6
Bertozzi, C.R.7
-
56
-
-
0034924188
-
Segmental isotopic labeling using expressed protein ligation
-
Cowburn D, Muir TW. Segmental isotopic labeling using expressed protein ligation. Methods Enzymol 2001; 339: 41-54.
-
(2001)
Methods Enzymol.
, vol.339
, pp. 41-54
-
-
Cowburn, D.1
Muir, T.W.2
-
57
-
-
0030267666
-
Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis
-
Muir TW, Dawson PE, Fitzgerald MC, Kent SBH. Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis. Chem. Biol. 1996; 3: 817-825.
-
(1996)
Chem. Biol.
, vol.3
, pp. 817-825
-
-
Muir, T.W.1
Dawson, P.E.2
Fitzgerald, M.C.3
Kent, S.B.H.4
-
59
-
-
0037459237
-
Thermodynamics of a designed protein catenane
-
Blankenship JW, Dawson PE. Thermodynamics of a designed protein catenane. J. Mol. Biol. 2003; 327: 537-548.
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 537-548
-
-
Blankenship, J.W.1
Dawson, P.E.2
-
60
-
-
0038771224
-
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
-
Urban S, Freeman M. Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Molecular Cell 2003; 11: 1425-1434.
-
(2003)
Molecular Cell
, vol.11
, pp. 1425-1434
-
-
Urban, S.1
Freeman, M.2
-
61
-
-
0033554426
-
Total chemical synthesis of the integral membrane protein influenza A virus M2 proton channel: Role of its cytoplasmic domain for pore assembly
-
Salom D, Lear JD, Kent SBH. DeGrado WF. Total chemical synthesis of the integral membrane protein influenza A virus M2 proton channel: role of its cytoplasmic domain for pore assembly. Biochemistry 1999; 38: 11 905-11 913.
-
(1999)
Biochemistry
, vol.38
, pp. 11905-11913
-
-
Salom, D.1
Lear, J.D.2
Kent, S.B.H.3
DeGrado, W.F.4
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