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Volumn 4, Issue 8, 2003, Pages 953-958

Vaccines for Moraxella catarrhalis and non-typeable Haemophilus influenzae

Author keywords

Animal model; Chronic obstructive pulmonary disease (COPD); Complement dependent bactericidal activity; Otitis media; Vaccine antigens

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; CATARRHALIS OUTER MEMBRANE PROTEIN B; CATARRHALIS OUTER MEMBRANE PROTEIN E; EPITOPE; HEMAGGLUTININ; HIGH TEMPERATURE REQUIREMENT PROTEASE A; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G3; INTEGRAL OUTER MEMBRANE PROTEIN; LIPOOLIGOSACCHARIDE; LIPOOLIGOSACCHARIDE PROTEIN CONJUGATE; LIPOPROTEIN D; MORAXELLA CATARRHALIS VACCINE; OUTER MEMBRANE ASSOCIATED PROTEIN; OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN 26; OUTER MEMBRANE PROTEIN D; OUTER MEMBRANE PROTEIN P4; OUTER MEMBRANE PROTEIN P5; OUTER MEMBRANE PROTEIN P6; PROTEIN OPAA; PROTEIN OPAB; RECOMBINANT 5' NUCLEOTIDASE ACTIVITY PROTEIN; TRANSFERRIN BINDING PROTEIN B; UBIQUITOUS SURFACE PROTEIN A1; UBIQUITOUS SURFACE PROTEIN A2; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 0141496285     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (65)
  • 1
    • 0024339586 scopus 로고
    • Epidemiology of otitis media during the first seven years of life in children in Greater Boston: A prospective, cohort study
    • Teele DW, Klein JO, Rosner B: Epidemiology of otitis media during the first seven years of life in children in Greater Boston: A prospective, cohort study. J Infect Dis (1989) 160(1):83-94.
    • (1989) J Infect Dis , vol.160 , Issue.1 , pp. 83-94
    • Teele, D.W.1    Klein, J.O.2    Rosner, B.3
  • 2
    • 0034919510 scopus 로고    scopus 로고
    • Behavior and developmental effects of otitis media with effusion into the teens
    • Bennett KE, Haggard MP, Silva PA, Stewart IA: Behavior and developmental effects of otitis media with effusion into the teens. Arch Dis Child (2001) 85(2):91-95.
    • (2001) Arch Dis Child , vol.85 , Issue.2 , pp. 91-95
    • Bennett, K.E.1    Haggard, M.P.2    Silva, P.A.3    Stewart, I.A.4
  • 4
    • 0037103420 scopus 로고    scopus 로고
    • New strains of bacteria and exacerbations of chronic obstructive pulmonary disease
    • Sethi S, Evans N, Grant BJ, Murphy TF: New strains of bacteria and exacerbations of chronic obstructive pulmonary disease. N Eng J Med (2002) 347(7):465-471.
    • (2002) N Eng J Med , vol.347 , Issue.7 , pp. 465-471
    • Sethi, S.1    Evans, N.2    Grant, B.J.3    Murphy, T.F.4
  • 5
    • 0037008318 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease surveillance - United States, 1971-2000
    • Mannino DM, Homa DM, Akinbami LJ, Ford ES, Redd SC: Chronic obstructive pulmonary disease surveillance - United States, 1971-2000. MMWR Surveil Summ (2002) 51(6):1-16.
    • (2002) MMWR Surveil Summ , vol.51 , Issue.6 , pp. 1-16
    • Mannino, D.M.1    Homa, D.M.2    Akinbami, L.J.3    Ford, E.S.4    Redd, S.C.5
  • 6
    • 0025719580 scopus 로고
    • Nasopharyngeal colonization by nontypeable Haemophilus influenzae in children: The effect of serum bactericidal antibody
    • Bernstein JM, Faden HS, Ogra PL: Nasopharyngeal colonization by nontypeable Haemophilus influenzae in children: The effect of serum bactericidal antibody. Otolaryngol Head Neck Surg (1991) 105(3):406-410.
    • (1991) Otolaryngol Head Neck Surg , vol.105 , Issue.3 , pp. 406-410
    • Bernstein, J.M.1    Faden, H.S.2    Ogra, P.L.3
  • 7
    • 0025741426 scopus 로고
    • Immunologic reactivity in the middle ear in otitis media with effusion
    • Bernstein JM: Immunologic reactivity in the middle ear in otitis media with effusion. Otolaryngol Clin North Am (1991) 24(4):845-858.
    • (1991) Otolaryngol Clin North Am , vol.24 , Issue.4 , pp. 845-858
    • Bernstein, J.M.1
  • 8
    • 0141760861 scopus 로고
    • Protection against experimental otitis media (AOM) by vaccination with protein D of Haemophilus influenzae (Hi)
    • Abs 972
    • Forsgren A, Akkoyunlu M, Hermansson A, Janson H, Ruan M, Melhus Å, Prellner K: Protection against experimental otitis media (AOM) by vaccination with protein D of Haemophilus influenzae (Hi). ICAAC (1992) 32: Abs 972
    • (1992) ICAAC , vol.32
    • Forsgren, A.1    Akkoyunlu, M.2    Hermansson, A.3    Janson, H.4    Ruan, M.5    Melhus, A.6    Prellner, K.7
  • 11
    • 0033021078 scopus 로고    scopus 로고
    • Protection against development of otitis media induced by nontypeable Haemophilus influenzae by both active and passive immunization in a chinchilla model of virus-bacterium superinfection
    • Bakaletz LO, Kennedy BJ, Novotny LA, Duquesne G, Cohen J, Lobet Y: Protection against development of otitis media induced by nontypeable Haemophilus influenzae by both active and passive immunization in a chinchilla model of virus-bacterium superinfection. Infect Immun (1999) 67(6):2746-2762.
    • (1999) Infect Immun , vol.67 , Issue.6 , pp. 2746-2762
    • Bakaletz, L.O.1    Kennedy, B.J.2    Novotny, L.A.3    Duquesne, G.4    Cohen, J.5    Lobet, Y.6
  • 12
    • 0035058393 scopus 로고    scopus 로고
    • Intranasal immunization enhances clearance of nontypeable Haemophilus influenzae and reduces stimulation of tumor necrosis factor α production in the murine model of otitis media
    • Sabirov A, Kodama S, Hirano T, Suzuki M, Mogi G: Intranasal immunization enhances clearance of nontypeable Haemophilus influenzae and reduces stimulation of tumor necrosis factor α production in the murine model of otitis media. Infect Immun (2001) 69(5):2964-2971.
    • (2001) Infect Immun , vol.69 , Issue.5 , pp. 2964-2971
    • Sabirov, A.1    Kodama, S.2    Hirano, T.3    Suzuki, M.4    Mogi, G.5
  • 14
    • 0032389277 scopus 로고    scopus 로고
    • Specific mucosal immunity and enhanced nasopharyngeal clearance of nontypeable Haemophilus influenzae after intranasal immunization with outer membrane protein P6 and cholera toxin
    • Hotomi M, Saito T, Yamanaka N: Specific mucosal immunity and enhanced nasopharyngeal clearance of nontypeable Haemophilus influenzae after intranasal immunization with outer membrane protein P6 and cholera toxin. Vaccine (1998) 16(20):1950-1956.
    • (1998) Vaccine , vol.16 , Issue.20 , pp. 1950-1956
    • Hotomi, M.1    Saito, T.2    Yamanaka, N.3
  • 15
    • 0030344603 scopus 로고    scopus 로고
    • Study on specific mucosal immunity by intranasal immunization of outer membrane protein P6 of Haemophilus influenzae with cholera toxin B subunit
    • Hotomi M, Yokoyama M, Kuki K, Togawa A, Yamanaka N: Study on specific mucosal immunity by intranasal immunization of outer membrane protein P6 of Haemophilus influenzae with cholera toxin B subunit. Acta Otolaryngol Suppl (1996) 523:150-152.
    • (1996) Acta Otolaryngol Suppl , vol.523 , pp. 150-152
    • Hotomi, M.1    Yokoyama, M.2    Kuki, K.3    Togawa, A.4    Yamanaka, N.5
  • 16
    • 0023511528 scopus 로고
    • Biologic activities of antibody to a peptidoglycan-associated lipoprotein of Haemophilus influenzae against multiple clinical isolates of H influenzae type B
    • Green BA, Quinn-Dey T, Zlotnick GW: Biologic activities of antibody to a peptidoglycan-associated lipoprotein of Haemophilus influenzae against multiple clinical isolates of H influenzae type B. Infect Immun (1987) 55(12):2878-2883.
    • (1987) Infect Immun , vol.55 , Issue.12 , pp. 2878-2883
    • Green, B.A.1    Quinn-Dey, T.2    Zlotnick, G.W.3
  • 18
    • 0025866724 scopus 로고
    • The e (P4) outer membrane protein of Haemophilus influenzae: Biologic activity of anti-e serum and cloning and sequencing of the structural gene
    • Green BA, Farley JE, Quinn-Dey T, Deich RA, Zlotnick GW: The e (P4) outer membrane protein of Haemophilus influenzae: Biologic activity of anti-e serum and cloning and sequencing of the structural gene. Infect Immun (1991) 59(9):3191-3198.
    • (1991) Infect Immun , vol.59 , Issue.9 , pp. 3191-3198
    • Green, B.A.1    Farley, J.E.2    Quinn-Dey, T.3    Deich, R.A.4    Zlotnick, G.W.5
  • 19
    • 0029910860 scopus 로고    scopus 로고
    • Biological activity of serum antibodies to a nonacylated form of lipoprotein D of Haemophilus influenzae
    • Akkoyunlu M, Janson H, Ruan M, Forsgren A: Biological activity of serum antibodies to a nonacylated form of lipoprotein D of Haemophilus influenzae. Infect Immun (1996) 64(11):4586-4592.
    • (1996) Infect Immun , vol.64 , Issue.11 , pp. 4586-4592
    • Akkoyunlu, M.1    Janson, H.2    Ruan, M.3    Forsgren, A.4
  • 20
    • 0034017268 scopus 로고    scopus 로고
    • Identification of a Haemophilus influenzae 5′-nucleotidase protein: Cloning of the nucA gene and immunogenicity and characterization of the NucA protein
    • Zagursky RJ, Ooi P, Jones KF, Fiske MJ, Smith RP, Green BA: Identification of a Haemophilus influenzae 5′-nucleotidase protein: Cloning of the nucA gene and immunogenicity and characterization of the NucA protein. Infect Immun (2000) 68(5):2525-2534.
    • (2000) Infect Immun , vol.68 , Issue.5 , pp. 2525-2534
    • Zagursky, R.J.1    Ooi, P.2    Jones, K.F.3    Fiske, M.J.4    Smith, R.P.5    Green, B.A.6
  • 21
    • 0029846855 scopus 로고    scopus 로고
    • Immunization with outer membrane protein P6 from nontypeable Haemophilus influenzae induces bactericidal antibody and affords protection in the chinchilla model of otitis media
    • DeMaria TF, Murwin DM, Leake ER: Immunization with outer membrane protein P6 from nontypeable Haemophilus influenzae induces bactericidal antibody and affords protection in the chinchilla model of otitis media. Infect Immun (1996) 64(12):5187-5192.
    • (1996) Infect Immun , vol.64 , Issue.12 , pp. 5187-5192
    • DeMaria, T.F.1    Murwin, D.M.2    Leake, E.R.3
  • 23
    • 0027243733 scopus 로고
    • Evaluation of mixtures of purified Haemophilus influenzae (Hi) outer membrane proteins in protection against challenge with nontypeable Hi in the chinchilla otitis media model
    • Green BA, Vazquez ME, Zlotnick GW, Quigley-Reape G, Swarts JD, Green I, Cowell JL, Bluestone CD, Doyle WJ: Evaluation of mixtures of purified Haemophilus influenzae (Hi) outer membrane proteins in protection against challenge with nontypeable Hi in the chinchilla otitis media model. Infect Immun (1993) 61(5):1950-1957.
    • (1993) Infect Immun , vol.61 , Issue.5 , pp. 1950-1957
    • Green, B.A.1    Vazquez, M.E.2    Zlotnick, G.W.3    Quigley-Reape, G.4    Swarts, J.D.5    Green, I.6    Cowell, J.L.7    Bluestone, C.D.8    Doyle, W.J.9
  • 24
    • 0029840977 scopus 로고    scopus 로고
    • Local and systemic antibody levels against protein D of Haemophilus influenzae following immunization and infection in rats
    • Akkoyunlu M, Forsgren A: Local and systemic antibody levels against protein D of Haemophilus influenzae following immunization and infection in rats. APMIS (1996) 104(10):709-717.
    • (1996) APMIS , vol.104 , Issue.10 , pp. 709-717
    • Akkoyunlu, M.1    Forsgren, A.2
  • 25
    • 0029968782 scopus 로고    scopus 로고
    • Immunization with high-molecular-weight adhesion proteins of nontypeable Haemophilus influenzae modifies experimental otitis media in chinchillas
    • Barenkamp SJ: Immunization with high-molecular-weight adhesion proteins of nontypeable Haemophilus influenzae modifies experimental otitis media in chinchillas. Infect Immun (1996) 64(4):1246-1251.
    • (1996) Infect Immun , vol.64 , Issue.6 , pp. 1246-1251
    • Barenkamp, S.J.1
  • 26
    • 0037108663 scopus 로고    scopus 로고
    • Immunization with Haemophilus influenzae Hap adhesin protects against nasopharyngeal colonization in experimental mice
    • note
    • Cutter D, Mason KW, Howell AP, Fink DL, Green BA, St. Geme JW 3rd: Immunization with Haemophilus influenzae Hap adhesin protects against nasopharyngeal colonization in experimental mice. J Infect Dis (2002) 186(8):1115-1121. This article demonstrates the effects of intranasal immunization with an adhesin on the protection against colonization with NTHi. This route of immunization should be a key method in future vaccine development for this pathogen.
    • (2002) J Infect Dis , vol.186 , Issue.8 , pp. 1115-1121
    • Cutter, D.1    Mason, K.W.2    Howell, A.P.3    Fink, D.L.4    Green, B.A.5    St. Geme J.W. III6
  • 27
    • 0036719965 scopus 로고    scopus 로고
    • The Haemophilus influenzae Hap autotransporter binds to fibronectin, laminin, and collagen IV
    • Fink DL, Green BA, St. Geme JW 3rd: The Haemophilus influenzae Hap autotransporter binds to fibronectin, laminin, and collagen IV. Infect Immun (2002) 70(9):4902-4907.
    • (2002) Infect Immun , vol.70 , Issue.9 , pp. 4902-4907
    • Fink, D.L.1    Green, B.A.2    St. Geme J.W. III3
  • 28
    • 0027987985 scopus 로고
    • A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells
    • St. Geme JW 3rd, De La Morena ML, Falkow S: A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells. Mol Microbiol (1994) 14(2):217-233.
    • (1994) Mol Microbiol , vol.14 , Issue.2 , pp. 217-233
    • St. Geme J.W. III1    De La Morena, M.L.2    Falkow, S.3
  • 29
    • 0037009227 scopus 로고    scopus 로고
    • Intranasal immunization with recombinant outer membrane protein P6 induces specific immune responses against nontypeable Haemophilus influenzae
    • note
    • Hotomi M, Yamanaka N, Shimada J, Suzumoto M, Ikeda Y, Sakai A, Arai J, Green B: Intranasal immunization with recombinant outer membrane protein P6 induces specific immune responses against nontypeable Haemophilus influenzae. Int J Pediatr Otorhinolaryngol (2002) 65(2):109-116. This paper reports that intranasal immunization with low levels of cholera toxin and an integral OMP can protect against colonization with NTHi in mice. This is a probable route of immunization for children.
    • (2002) Int J Pediatr Otorhinolaryngol , vol.65 , Issue.2 , pp. 109-116
    • Hotomi, M.1    Yamanaka, N.2    Shimada, J.3    Suzumoto, M.4    Ikeda, Y.5    Sakai, A.6    Arai, J.7    Green, B.8
  • 30
    • 0031924972 scopus 로고    scopus 로고
    • Potential of a novel protein, OMP26, from nontypeable Haemophilus influenzae to enhance pulmonary clearance in a rat model
    • Kyd JM, Cripps AW: Potential of a novel protein, OMP26, from nontypeable Haemophilus influenzae to enhance pulmonary clearance in a rat model. Infect Immun (1998) 66(5):2272-2278.
    • (1998) Infect Immun , vol.66 , Issue.5 , pp. 2272-2278
    • Kyd, J.M.1    Cripps, A.W.2
  • 31
    • 0029096438 scopus 로고
    • Identification and characterization of a cell envelope protein of Haemophilus influenzae contributing to phase variation in colony opacity and nasopharyngeal colonization
    • Weiser JN, Chong ST, Greenberg D, Fong W: Identification and characterization of a cell envelope protein of Haemophilus influenzae contributing to phase variation in colony opacity and nasopharyngeal colonization. Mol Microbiol (1995) 17(3):555-564.
    • (1995) Mol Microbiol , vol.17 , Issue.3 , pp. 555-564
    • Weiser, J.N.1    Chong, S.T.2    Greenberg, D.3    Fong, W.4
  • 32
    • 0344974629 scopus 로고
    • Nontypeable Haemophilus influenzae lipooligosaccharide conjugates as vaccine candidates against NTHi
    • Ginsberg HS, Brown F, Norrby E (Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, USA
    • Green BA, Meredith ES, Edwards L, Jones KF: Nontypeable Haemophilus influenzae lipooligosaccharide conjugates as vaccine candidates against NTHi. In: Vaccines 94: Modern Approaches to New Vaccines Including Prevention of AIDS. Ginsberg HS, Brown F, Norrby E (Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, USA (1994):125-129.
    • (1994) Vaccines 94: Modern Approaches to New Vaccines Including Prevention of AIDS , pp. 125-129
    • Green, B.A.1    Meredith, E.S.2    Edwards, L.3    Jones, K.F.4
  • 33
    • 1842411846 scopus 로고    scopus 로고
    • Detoxified lipooligosaccharide from nontypeable Haemophilus influenzae conjugated to proteins confers protection against otitis media in chinchillas
    • Gu X-X, Sun J, Jin S, Barenkamp SJ, Lim DJ, Robbins JB, Battey J: Detoxified lipooligosaccharide from nontypeable Haemophilus influenzae conjugated to proteins confers protection against otitis media in chinchillas. Infect Immun (1997) 65(11):4488-4493.
    • (1997) Infect Immun , vol.65 , Issue.11 , pp. 4488-4493
    • Gu, X.-X.1    Sun, J.2    Jin, S.3    Barenkamp, S.J.4    Lim, D.J.5    Robbins, J.B.6    Battey, J.7
  • 34
    • 0031954139 scopus 로고    scopus 로고
    • Synthesis and characterization of lipooligosaccharide-based conjugates as vaccine candidates for Moraxella (Branhamella) catarrhalis
    • note
    • Gu X-X, Chen J, Barenkamp SJ, Robbins JB, Tsai C-M, Lim DJ, Battey J: Synthesis and characterization of lipooligosaccharide-based conjugates as vaccine candidates for Moraxella (Branhamella) catarrhalis. Infect Immun (1998) 66(5):1891-1897. This study demonstrated that LOS conjugates can be immunogenic and that antibodies to it are bactericidal.
    • (1998) Infect Immun , vol.66 , Issue.5 , pp. 1891-1897
    • Gu, X.-X.1    Chen, J.2    Barenkamp, S.J.3    Robbins, J.B.4    Tsai, C.-M.5    Lim, D.J.6    Battey, J.7
  • 35
    • 0033986927 scopus 로고    scopus 로고
    • Biological activities of antibodies elicited by lipooligosaccharide based-conjugate vaccines of nontypeable Haemophilus influenzae in an otitis media model
    • note
    • Sun J, Chen J, Cheng Z, Robbins JB, Battey JF, Gu XX: Biological activities of antibodies elicited by lipooligosaccharide based-conjugate vaccines of nontypeable Haemophilus influenzae in an otitis media model. Vaccine (2000) 18(13):1264-1272. This paper describes the activity of LOS conjugate-antibodies against NTHi. Conjugation of polysaccharides has proven to be one of the most effective techniques for immunization and this common antigen may prove to be an efficacious vaccine if common epitopes are immunogenic.
    • (2000) Vaccine , vol.18 , Issue.13 , pp. 1264-1272
    • Sun, J.1    Chen, J.2    Cheng, Z.3    Robbins, J.B.4    Battey, J.F.5    Gu, X.X.6
  • 36
    • 0033404869 scopus 로고    scopus 로고
    • The structural heterogeneity of the lipooligosaccharide (LOS) expressed by pathogenic non-typeable Haemophilus influenzae strain NTHi 9274
    • Rahman MM, Gu XX, Tsai CM, Kolli VS, Carlson RW: The structural heterogeneity of the lipooligosaccharide (LOS) expressed by pathogenic non-typeable Haemophilus influenzae strain NTHi 9274. Glycobiology (1999) 9(12):1371-1380.
    • (1999) Glycobiology , vol.9 , Issue.12 , pp. 1371-1380
    • Rahman, M.M.1    Gu, X.X.2    Tsai, C.M.3    Kolli, V.S.4    Carlson, R.W.5
  • 38
    • 0025147104 scopus 로고
    • Branhamella catarrhalis: An organism gaining respect as a pathogen
    • note
    • Catlin BW: Branhamella catarrhalis: An organism gaining respect as a pathogen. Clin Microbiol Rev (1990) 3(4):293-320. This comprehensive review is a landmark in the M catarrhalis literature. It established once and for all that M catarrhalis is an important pathogen.
    • (1990) Clin Microbiol Rev , vol.3 , Issue.4 , pp. 293-320
    • Catlin, B.W.1
  • 40
    • 0032974748 scopus 로고    scopus 로고
    • The levels and bactericidal capacity of antibodies directed against the UspA1 and UspA2 outer membrane proteins of Moraxella (Branhamella) catarrhalis in adults and children
    • note
    • Chen D, Barniak V, VanDerMeid KR, McMichael JC: The levels and bactericidal capacity of antibodies directed against the UspA1 and UspA2 outer membrane proteins of Moraxella (Branhamella) catarrhalis in adults and children. Infect Immun (1999) 67(3):1310-1316. This paper reports that the bulk of the bactericidal antibodies resulting from natural exposure of individuals to M catarrhalis are directed toward the UspA proteins.
    • (1999) Infect Immun , vol.67 , Issue.3 , pp. 1310-1316
    • Chen, D.1    Barniak, V.2    VanDerMeid, K.R.3    McMichael, J.C.4
  • 41
    • 0028032315 scopus 로고
    • Association of Gm allotypes with the antibody response to the outer membrane proteins of a common upper respiratory tract organism, Moraxella catarrhalis
    • note
    • Goldblatt D, Scadding GK, Lund VJ, Wade AM, Turner MW, Pandey JP: Association of Gm allotypes with the antibody response to the outer membrane proteins of a common upper respiratory tract organism, Moraxella catarrhalis. J Immunol (1994) 153(11):5316-5320. This paper established the importance of IgG3 antibodies in protecting individuals from M catarrhalis infections.
    • (1994) J Immunol , vol.153 , Issue.11 , pp. 5316-5320
    • Goldblatt, D.1    Scadding, G.K.2    Lund, V.J.3    Wade, A.M.4    Turner, M.W.5    Pandey, J.P.6
  • 42
    • 0028022186 scopus 로고
    • Influence of Gm allotype on the IgG subclass response to streptococcal M protein and outer membrane proteins of Moraxella catarrhalis
    • Carson RT, McDonald DF, Kehoe MA, Calvert JE: Influence of Gm allotype on the IgG subclass response to streptococcal M protein and outer membrane proteins of Moraxella catarrhalis. Immunology (1994) 83(1):107-113.
    • (1994) Immunology , vol.83 , Issue.1 , pp. 107-113
    • Carson, R.T.1    McDonald, D.F.2    Kehoe, M.A.3    Calvert, J.E.4
  • 44
    • 0037157246 scopus 로고    scopus 로고
    • A new intra-NALT route elicits mucosal and systemic immunity against Moraxella catarrhalis in a mouse challenge model
    • Hou Y, Hu W-G, Hirano T, Gu X-X: A new intra-NALT route elicits mucosal and systemic immunity against Moraxella catarrhalis in a mouse challenge model. Vaccine (2002) 20(17-18):2375-2381.
    • (2002) Vaccine , vol.20 , Issue.17-18 , pp. 2375-2381
    • Hou, Y.1    Hu, W.-G.2    Hirano, T.3    Gu, X.-X.4
  • 45
    • 0029934422 scopus 로고    scopus 로고
    • Evaluation of purified UspA from Moraxella catarrhalis as a vaccine in a murine model after active immunization
    • Chen D, McMichael JC, VanDerMeid KR, Hahn D, Mininni T, Cowell J, Eldridge J: Evaluation of purified UspA from Moraxella catarrhalis as a vaccine in a murine model after active immunization. Infect Immun (1996) 64(6):1900-1905.
    • (1996) Infect Immun , vol.64 , Issue.6 , pp. 1900-1905
    • Chen, D.1    McMichael, J.C.2    Vandermeid, K.R.3    Hahn, D.4    Mininni, T.5    Cowell, J.6    Eldridge, J.7
  • 46
    • 0036073628 scopus 로고    scopus 로고
    • A hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination and immunoglobulin D-binding activities
    • note
    • Pearson MM, Lafontaine ER, Wagner NJ, St Geme JW III, Hansen EJ: A hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination and immunoglobulin D-binding activities. Infect Immun (2002) 70(8):4523-4533. The differences and similarities of the UspA1, UspA2 and Hag proteins are described in this paper.
    • (2002) Infect Immun , vol.70 , Issue.8 , pp. 4523-4533
    • Pearson, M.M.1    Lafontaine, E.R.2    Wagner, N.J.3    St. Geme J.W. III4    Hansen, E.J.5
  • 49
    • 0030827158 scopus 로고    scopus 로고
    • A 200 kDa protein is associated with haemagglutinating isolates of Moraxella (Branhamella) catarrhalis
    • Fitzgerald M, Mulcahy R, Murphy S, Keane C, Coakley D, Scott T: A 200 kDa protein is associated with haemagglutinating isolates of Moraxella (Branhamella) catarrhalis. FEMS Immunol Med Microbiol (1997) 18(3):209-216.
    • (1997) FEMS Immunol Med Microbiol , vol.18 , Issue.3 , pp. 209-216
    • Fitzgerald, M.1    Mulcahy, R.2    Murphy, S.3    Keane, C.4    Coakley, D.5    Scott, T.6
  • 51
    • 0037086631 scopus 로고    scopus 로고
    • The outer membrane proteins UspA1 and UspA2 of Moraxella catarrhalis are highly conserved in nasopharyngeal isolates from young children
    • Meier PS, Troller R, Grivea IN, Syrogiannopoulos GA, Aebi C: The outer membrane proteins UspA1 and UspA2 of Moraxella catarrhalis are highly conserved in nasopharyngeal isolates from young children. Vaccine (2002) 20(13-14):1754-4760.
    • (2002) Vaccine , vol.20 , Issue.13-14 , pp. 1754-4760
    • Meier, P.S.1    Troller, R.2    Grivea, I.N.3    Syrogiannopoulos, G.A.4    Aebi, C.5
  • 52
    • 0035110759 scopus 로고    scopus 로고
    • Expression of the Moraxella catarrhalis UspA1 protein undergoes phase variation and is regulated at the transcriptional level
    • Lafontaine ER, Wagner NJ, Hansen EJ: Expression of the Moraxella catarrhalis UspA1 protein undergoes phase variation and is regulated at the transcriptional level. J Bacteriol (2001) 183(5):1540-1551.
    • (2001) J Bacteriol , vol.183 , Issue.5 , pp. 1540-1551
    • Lafontaine, E.R.1    Wagner, N.J.2    Hansen, E.J.3
  • 54
    • 0027175167 scopus 로고
    • A major outer membrane protein of Moraxella catarrhalis is a target for antibodies that enhance pulmonary clearance of the pathogen in an animal model
    • Helminen ME, Maciver I, Latimer JL, Cope LD, McCracken GH, Hansen EJ: A major outer membrane protein of Moraxella catarrhalis is a target for antibodies that enhance pulmonary clearance of the pathogen in an animal model. Infect Immun (1993) 61(5):2003-2010.
    • (1993) Infect Immun , vol.61 , Issue.5 , pp. 2003-2010
    • Helminen, M.E.1    Maciver, I.2    Latimer, J.L.3    Cope, L.D.4    McCracken, G.H.5    Hansen, E.J.6
  • 55
    • 0033791972 scopus 로고    scopus 로고
    • Antigenic structure of outer membrane protein E of Moraxella catarrhalis and construction and characterization of mutants
    • Murphy TF, Brauer AL, Yuskiw N, Hiltke TJ: Antigenic structure of outer membrane protein E of Moraxella catarrhalis and construction and characterization of mutants. Infect Immun (2000) 68(11):6250-6256.
    • (2000) Infect Immun , vol.68 , Issue.11 , pp. 6250-6256
    • Murphy, T.F.1    Brauer, A.L.2    Yuskiw, N.3    Hiltke, T.J.4
  • 56
    • 0031736510 scopus 로고    scopus 로고
    • Enhancement of pulmonary clearance of Moraxella (Branhamella) catarrhalis following immunization with outer membrane protein CD in a mouse model
    • Murphy TF, Kyd JM, John A, Kirkham C, Cripps AW: Enhancement of pulmonary clearance of Moraxella (Branhamella) catarrhalis following immunization with outer membrane protein CD in a mouse model. J Infect Dis (1998) 178(6):1667-1675.
    • (1998) J Infect Dis , vol.178 , Issue.6 , pp. 1667-1675
    • Murphy, T.F.1    Kyd, J.M.2    John, A.3    Kirkham, C.4    Cripps, A.W.5
  • 57
    • 0031020247 scopus 로고    scopus 로고
    • Middle ear mucin glycoprotein: Purification and interaction with nontypeable Haemophilus influenzae and Moraxella catarrhalis
    • Reddy MS, Murphy TF, Faden HS, Bernstein JM: Middle ear mucin glycoprotein: Purification and interaction with nontypeable Haemophilus influenzae and Moraxella catarrhalis. Otolaryngol Head Neck Surg (1997) 116(2):175-180.
    • (1997) Otolaryngol Head Neck Surg , vol.116 , Issue.2 , pp. 175-180
    • Reddy, M.S.1    Murphy, T.F.2    Faden, H.S.3    Bernstein, J.M.4
  • 58
    • 0025141277 scopus 로고
    • Serological typing of Branhamella catarrhalis strains on the basis of lipopolysaccharide antigens
    • note
    • Vaneechoutte M, Verschraegen G, Claeys G, Van Den Abeele AM: Serological typing of Branhamella catarrhalis strains on the basis of lipopolysaccharide antigens. J Clin Microbiol (1990) 28(2):182-187. The basis for the serological typing of LOS of M catarrhalis was established in this paper.
    • (1990) J Clin Microbiol , vol.28 , Issue.2 , pp. 182-187
    • Vaneechoutte, M.1    Verschraegen, G.2    Claeys, G.3    Van Den Abeele, A.M.4
  • 59
    • 0028854092 scopus 로고
    • Structural studies of the O-antigen oligosaccharides from two strains of Moraxella catarrhalis serotype C
    • Edebrink P, Jansson PE, Rahman MM, Widmalm G, Holme T, Rahman M: Structural studies of the O-antigen oligosaccharides from two strains of Moraxella catarrhalis serotype C. Carbohydr Res (1995) 266(2):237-261.
    • (1995) Carbohydr Res , vol.266 , Issue.2 , pp. 237-261
    • Edebrink, P.1    Jansson, P.E.2    Rahman, M.M.3    Widmalm, G.4    Holme, T.5    Rahman, M.6
  • 60
    • 0001429402 scopus 로고
    • Structural elucidation of the backbone of oligosaccharide from the lipopolysaccharide of Moraxella catarrhalis serotype A
    • Masoud H, Perry MB, Brisson J-R, Uhrin D, Richards JC: Structural elucidation of the backbone of oligosaccharide from the lipopolysaccharide of Moraxella catarrhalis serotype A. Can J Chem (1994) 72:1466-1477.
    • (1994) Can J Chem , vol.72 , pp. 1466-1477
    • Masoud, H.1    Perry, M.B.2    Brisson, J.-R.3    Uhrin, D.4    Richards, J.C.5
  • 61
    • 0035118421 scopus 로고    scopus 로고
    • Functional characteristics of a protective monoclonal antibody against serotype A and C lipooligosaccharides from Moraxella catarrhalis
    • Hu W-G, Chen J, McMichael JC, Gu X-X: Functional characteristics of a protective monoclonal antibody against serotype A and C lipooligosaccharides from Moraxella catarrhalis. Infect Immun (2001) 69(3):1358-1363.
    • (2001) Infect Immun , vol.69 , Issue.3 , pp. 1358-1363
    • Hu, W.-G.1    Chen, J.2    McMichael, J.C.3    Gu, X.-X.4
  • 62
    • 0036840446 scopus 로고    scopus 로고
    • Specific immune responses and enhancement of murine pulmonary clearance of Moraxella catarrhalis by intranasal immunization with a detoxified lipooligosaccharide conjugate vaccine
    • Jiao X, Hirano T, Hou Y, Gu X-X: Specific immune responses and enhancement of murine pulmonary clearance of Moraxella catarrhalis by intranasal immunization with a detoxified lipooligosaccharide conjugate vaccine. Infect Immun (2002) 70(11):5982-5989.
    • (2002) Infect Immun , vol.70 , Issue.11 , pp. 5982-5989
    • Jiao, X.1    Hirano, T.2    Hou, Y.3    Gu, X.-X.4
  • 63
    • 0038673827 scopus 로고    scopus 로고
    • Safety evaluation of toxin adjuvants delivered intranasally
    • National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA; note
    • Safety evaluation of toxin adjuvants delivered intranasally: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA (2002). http://www.niaid.nih.gov/dmid/enteric/intranasal.htm This is a critical reference for scientists interested in intranasal immunization. The issues regarding the intranasal use of enterotoxin adjuvants are highlighted and the challenges for regulatory approval of this powerful class of mucosal adjuvants are presented.
    • (2002)
  • 64
    • 0005778110 scopus 로고    scopus 로고
    • Nucleic acids encoding high molecular weight major outer membrane protein of Moraxella
    • US-05808024
    • Connaught Laboratories Ltd (Sasaki K, Harkness RE, Loosmoore SM, Klein MH): Nucleic acids encoding high molecular weight major outer membrane protein of Moraxella. US-05808024 (1998).
    • (1998)
    • Sasaki, K.1    Harkness, R.E.2    Loosmoore, S.M.3    Klein, M.H.4
  • 65
    • 24244474448 scopus 로고    scopus 로고
    • Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof
    • US-06214981
    • Antex Biologics Inc (Tucker K, Plosila L, Tillman UF): Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof. US-06214981 (2001).
    • (2001)
    • Tucker, K.1    Plosila, L.2    Tillman, U.F.3


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