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Volumn 64, Issue 4, 2003, Pages 865-875

Carbamoylcholine homologs: Novel and potent agonists at neuronal nicotinic acetylcholine receptors

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE ALPHA2BETA2 RECEPTOR; ACETYLCHOLINE ALPHA3BETA4 RECEPTOR; ACETYLCHOLINE ALPHA4BETA2 RECEPTOR; ACETYLCHOLINE ALPHA4BETA4 RECEPTOR; CARBACHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT; EPIBATIDINE; METHYLCARBACHOL; MUSCARINIC AGENT; N,N DIMETHYLCARBAMOYL N,N DIMETHYLAMINOETHANOL; N,N DIMETHYLCARBAMOYLCHOLINE; NANOPARTICLE; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; TERTIARY AMINE; UNCLASSIFIED DRUG;

EID: 0141457718     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.4.865     Document Type: Article
Times cited : (50)

References (38)
  • 1
    • 0022930980 scopus 로고
    • 3H]Methylcarbamylcholine, a new radioligand for studying brain nicotinic receptors
    • 3H]Methylcarbamylcholine, a new radioligand for studying brain nicotinic receptors. Biochem Pharmacol 35:4199-4202.
    • (1986) Biochem Pharmacol , vol.35 , pp. 4199-4202
    • Abood, L.G.1    Grassi, S.2
  • 4
    • 0036721041 scopus 로고    scopus 로고
    • Effects of pyridine ring substitutions on affinity, efficacy and subtype selectivity of neuronal nicotinic receptor agonist epibatidine
    • Avalos M, Parker MJ, Maddox FN, Carroll FI, and Luetje CW (2002) Effects of pyridine ring substitutions on affinity, efficacy and subtype selectivity of neuronal nicotinic receptor agonist epibatidine. J Pharmacol Exp Ther 302:1246-1252.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 1246-1252
    • Avalos, M.1    Parker, M.J.2    Maddox, F.N.3    Carroll, F.I.4    Luetje, C.W.5
  • 7
    • 0028288443 scopus 로고
    • Functional expression and properties of the human skeletal muscle sodium channel
    • Chahine M, Bennett PB, George AL Jr, and Horn R (1994) Functional expression and properties of the human skeletal muscle sodium channel. Pflügers Arch 427:136-142.
    • (1994) Pflügers Arch , vol.427 , pp. 136-142
    • Chahine, M.1    Bennett, P.B.2    George A.L., Jr.3    Horn, R.4
  • 8
    • 0030941561 scopus 로고    scopus 로고
    • Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα7 expressed in Xenopus oocytes
    • Chavez-Noriega LE, Crona JH, Washburn MS, Urrutia A, Elliott KJ, and Johnson EC (1997) Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα7 expressed in Xenopus oocytes. J Pharmacol Exp Ther 280:346-356.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 346-356
    • Chavez-Noriega, L.E.1    Crona, J.H.2    Washburn, M.S.3    Urrutia, A.4    Elliott, K.J.5    Johnson, E.C.6
  • 9
    • 0028980450 scopus 로고
    • Regions of β2 and β4 responsible for differences between the steady state dose-response relationships of the α3β2 and α3β4 neuronal nicotinic receptors
    • Cohen BN, Figl A, Quick MW, Labarca C, Davidson N, and Lester HA (1995) Regions of β2 and β4 responsible for differences between the steady state dose-response relationships of the α3β2 and α3β4 neuronal nicotinic receptors. J Gen Physiol 105:745-764.
    • (1995) J Gen Physiol , vol.105 , pp. 745-764
    • Cohen, B.N.1    Figl, A.2    Quick, M.W.3    Labarca, C.4    Davidson, N.5    Lester, H.A.6
  • 11
    • 0028144005 scopus 로고
    • Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes
    • Covernton PJ, Kojima H, Sivilotti LG, Gibb AJ, and Colquhoun D (1994) Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. J Physiol 481:27-34.
    • (1994) J Physiol , vol.481 , pp. 27-34
    • Covernton, P.J.1    Kojima, H.2    Sivilotti, L.G.3    Gibb, A.J.4    Colquhoun, D.5
  • 13
    • 0034607693 scopus 로고    scopus 로고
    • Amino acid determinants of α7 nicotinic acetylcholine receptor surface expression
    • Dineley KT and Patrick JW (2000) Amino acid determinants of α7 nicotinic acetylcholine receptor surface expression. J Biol Chem 275:13974-13985.
    • (2000) J Biol Chem , vol.275 , pp. 13974-13985
    • Dineley, K.T.1    Patrick, J.W.2
  • 15
    • 0034924993 scopus 로고    scopus 로고
    • Competitive neuronal nicotinic receptor antagonists: A new direction for drug discovery
    • Dwoskin LP and Crooks PA (2001) Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery. J Pharmacol Exp Ther 298:395-402.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 395-402
    • Dwoskin, L.P.1    Crooks, P.A.2
  • 16
    • 0035424943 scopus 로고    scopus 로고
    • Therapeutic opportunities from muscarinic receptor research
    • Eglen RM, Choppin A, and Watson N (2001) Therapeutic opportunities from muscarinic receptor research. Trends Pharmacol Sci 22:409-414.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 409-414
    • Eglen, R.M.1    Choppin, A.2    Watson, N.3
  • 18
    • 0344490327 scopus 로고    scopus 로고
    • Membrane potential fluorescence: A rapid and highly sensitive assay for nicotinic receptor channel function
    • Fitch RW, Xiao Y, Kellar KJ, and Daly JW (2003) Membrane potential fluorescence: a rapid and highly sensitive assay for nicotinic receptor channel function. Proc Natl Acad Sci USA 100:4909-4914.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4909-4914
    • Fitch, R.W.1    Xiao, Y.2    Kellar, K.J.3    Daly, J.W.4
  • 20
    • 0031450275 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors as targets for drug discovery
    • Holladay MW, Dart MJ, and Lynch JK (1997) Neuronal nicotinic acetylcholine receptors as targets for drug discovery. J Med Chem 40:4169-4194.
    • (1997) J Med Chem , vol.40 , pp. 4169-4194
    • Holladay, M.W.1    Dart, M.J.2    Lynch, J.K.3
  • 21
    • 0036480194 scopus 로고    scopus 로고
    • Emerging structure of the nicotinic acetylcholine receptors
    • Karlin A (2002) Emerging structure of the nicotinic acetylcholine receptors. Nature (Lond) Rev Neurosci 3:102-114.
    • (2002) Nature (Lond) Rev Neurosci , vol.3 , pp. 102-114
    • Karlin, A.1
  • 25
    • 0031242019 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in health and disease
    • Lindstrom J (1997) Nicotinic acetylcholine receptors in health and disease. Mol Neurobiol 152:193-222.
    • (1997) Mol Neurobiol , vol.152 , pp. 193-222
    • Lindstrom, J.1
  • 27
    • 0037350806 scopus 로고    scopus 로고
    • Interactions of atropine with heterologously expressed and native alpha3 subunit-containing nicotinic acetylcholine receptors
    • Parker JC, Sarkar D, Quick MW, and Lester RA (2003) Interactions of atropine with heterologously expressed and native alpha3 subunit-containing nicotinic acetylcholine receptors. Br J Pharmacol 138:801-810.
    • (2003) Br J Pharmacol , vol.138 , pp. 801-810
    • Parker, J.C.1    Sarkar, D.2    Quick, M.W.3    Lester, R.A.4
  • 28
    • 0032438649 scopus 로고    scopus 로고
    • Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity
    • Parker MJ, Beck A, and Luetje CW (1998) Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity. Mol Pharmacol 54: 1132-1139.
    • (1998) Mol Pharmacol , vol.54 , pp. 1132-1139
    • Parker, M.J.1    Beck, A.2    Luetje, C.W.3
  • 29
    • 0026027645 scopus 로고
    • Structure-activity relationships for various N-alkylcarbamyl esters of choline with selective nicotinic cholinergic properties
    • Punzi JS, Banerjee S, and Abood LG (1991) Structure-activity relationships for various N-alkylcarbamyl esters of choline with selective nicotinic cholinergic properties. Biochem Pharmacol 41:465-467.
    • (1991) Biochem Pharmacol , vol.41 , pp. 465-467
    • Punzi, J.S.1    Banerjee, S.2    Abood, L.G.3
  • 30
    • 0023820777 scopus 로고
    • 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine and polyamines
    • 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine and polyamines. J Neurochem 51:830-836.
    • (1988) J Neurochem , vol.51 , pp. 830-836
    • Ransom, R.W.1    Stec, N.L.2
  • 31
    • 0038469953 scopus 로고    scopus 로고
    • Cholinergic nicotinic receptors: Competitive ligands, allosteric modulators and their potential applications
    • Romanelli MN and Gualtieri F (2003) Cholinergic nicotinic receptors: competitive ligands, allosteric modulators and their potential applications. Med Res Rev 23: 393-426.
    • (2003) Med Res Rev , vol.23 , pp. 393-426
    • Romanelli, M.N.1    Gualtieri, F.2
  • 32
    • 0032951304 scopus 로고    scopus 로고
    • Ligand binding and activation of rat nicotinic α4β2 receptors stably expressed in HEK293 cells
    • Sabey K, Paradiso K, Zhang J, and Steinbach JH (1999) Ligand binding and activation of rat nicotinic α4β2 receptors stably expressed in HEK293 cells. Mol Pharmacol 55:58-66.
    • (1999) Mol Pharmacol , vol.55 , pp. 58-66
    • Sabey, K.1    Paradiso, K.2    Zhang, J.3    Steinbach, J.H.4
  • 36
    • 0031595642 scopus 로고    scopus 로고
    • Rat α3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: Pharmacology of ligand binding and function
    • Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J, and Kellar KJ (1998) Rat α3/β4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function. Mol Pharmacol 54:322-333.
    • (1998) Mol Pharmacol , vol.54 , pp. 322-333
    • Xiao, Y.1    Meyer, E.L.2    Thompson, J.M.3    Surin, A.4    Wroblewski, J.5    Kellar, K.J.6
  • 37
    • 0036591656 scopus 로고    scopus 로고
    • Cation-π interactions in ligand recognition and catalysis
    • Zacharias N and Dougherty DA (2002) Cation-π interactions in ligand recognition and catalysis. Trends Pharmacol Sci 23:281-287.
    • (2002) Trends Pharmacol Sci , vol.23 , pp. 281-287
    • Zacharias, N.1    Dougherty, D.A.2
  • 38
    • 0032514762 scopus 로고    scopus 로고
    • From ab initio quantum mechanics to molecular neurobiology: A cation-π binding site in the nicotinic receptor
    • Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, and Dougherty DA (1998) From ab initio quantum mechanics to molecular neurobiology: a cation-π binding site in the nicotinic receptor. Proc Natl Acad Sci USA 95:12088-12093.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12088-12093
    • Zhong, W.1    Gallivan, J.P.2    Zhang, Y.3    Li, L.4    Lester, H.A.5    Dougherty, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.