A bacterial conjugation machinery recruited for pathogenesis

Molecular Microbiology

Volumn 49, Issue 5, 2003, Pages 1253-1266

  Seubert, Anja ^a   Hiestand, Rosemarie ^a   De La Cruz, Fernando ^b   Dehio, Christoph ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM CONJUGATION; BARTONELLA; BARTONELLA TRIBOCORUM; CONTROLLED STUDY; DNA TRANSFER; GENE DUPLICATION; GENE EXPRESSION; GENE LOCUS; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITISM; PATHOGENESIS; PLASMID; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

BARTONELLA; BASE SEQUENCE; CELLS, CULTURED; CONJUGATION, GENETIC; CONSERVED SEQUENCE; DNA, BACTERIAL; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; GENE ORDER; GENES, BACTERIAL; GENES, REPORTER; GENETIC COMPLEMENTATION TEST; GENOMIC ISLANDS; GENOMIC LIBRARY; HUMANS; MOLECULAR SEQUENCE DATA; R FACTORS; SEQUENCE HOMOLOGY;

ANIMALIA; BACTERIA (MICROORGANISMS); BARTONELLA; BARTONELLA TRIBOCORUM; BROAD HOST RANGE PLASMIDS; EUKARYOTA; NEGIBACTERIA;

EID: 0141454925     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03650.x     Document Type: Article

References (41)

1. Baron, C., O'Callaghan, D., and Lanka, E. (2002) Bacterial secrets of secretion: EuroConference on the biology of type IV secretion processes. Mol Microbiol 43: 1359-1365.
2. Bartolome, B., Jubete, Y., Martinez, E., and de la Cruz, F. (1991) Construction and properties of a family of pACYC184-derived cloning vectors compatible with pBR322 and its derivatives. Gene 102: 75-78.
3. Bolland, S. (1991) Genes involved in production of plasmid R388 conjugative pilus. PhD Thesis, University of Cantabria, Spain.
4. Bolland, S., Llosa, M., Avila, P., and de la Cruz, F. (1990) General organization of the conjugal transfer genes of the IncW plasmid R388 and interactions between R388 and IncN and IncP plasmids. J Bacteriol 172: 5795-5802.
5. Boschiroli, M.L., Ouahrani-Bettache, S., Foulongne, V., Michauet Cazevieille, C., Liautard, J.P., Ramuz, M., and O'Callaghan, D. (2002) The Brucella suis virB operon is induced intracellularly in macrophages. Proc Natl Acad Sci USA 99: 1544-1549.
6. Brosius, J., and Holy, A. (1984) Regulation of ribosomal RNA promoters with a synthetic lac operator. Proc Natl Acad Sci USA 81: 6929-6933.
7. Cao, T.B., and Saier, M.H., Jr (2001) Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions. Microbiology 147: 3201-3214.
8. Christie, P.J. (2001) Type IV secretion: intercellular transfer of macromolecules by systems ancestrally related to conjugation machines. Mol Microbiol 40: 294-305.
9. Christie, P.J., and Vogel, J.P. (2000) Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells. Trends Microbiol 8: 354-360.
10. Dang, T.A., Zhou, X.R., Graf, B., and Christie, P.J. (1999) Dimerization of the Agrobacterium tumefaciens VirB4 ATPase and the effect of ATP-binding cassette mutations on the assembly and function of the T-DNA transporter. Mol Microbiol 32: 1239-1253.
11. Dehio, C. (2001) Bartonella interactions with endothelial cells and erythrocytes. Trends Microbiol 9: 279-285.
12. Dehio, C., and Meyer, M. (1997) Maintenance of broad-host-range incompatibility group P and group Q plasmids and transposition of Tn5 in Bartonella henselae following conjugal plasmid transfer from Escherichia coli. J Bacteriol 179: 538-540.
13. Dehio, C., Meyer, M., Berger, J., Schwarz, H., and Lanz, C. (1997) Interaction of Bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome. J Cell Sci 110: 2141-2154.
14. Dehio, M., Knorre, A., Lanz, C., and Dehio, C. (1998) Construction of versatile high-level expression vectors for Bartonella henselae and the use of green fluorescent protein as a new expression marker. Gene 215: 223-229.
15. Ditta, G., Stanfield, S., Corbin, D., and Helinski, D.R. (1980) Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc Natl Acad Sci USA 77: 7347-7351.
16. Hacker, J., Blum-Oehler, G., Muhldorfer, I., and Tschape, H. (1997) Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol Microbiol 23: 1089-1097.
17. Heller, R., Riegel, P., Hansmann, Y., Delacour, G., Bermond, D., Dehio, C., et al. (1998) Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats. Int J Syst Bacteriol 48: 1333-1339.
18. Kempf, V.A.J., Schaller, M., Behrendt, S., Volkmann, B., Aepfelbacher, M., Cakman, I., and Autenrieth, I.B. (2000) Interaction of Bartonella henselae with endothelial cells results in rapid bacterial rRNA synthesis and replication. Cell Microbiol 2: 431-441.
19. Kihara, D., and Kanehisa, M. (2000) Tandem clusters of membrane proteins in complete genome sequences. Genome Res 10: 731-743.
20. Krall, L., Wiedemann, U., Unsin, G., Weiss, S., Domke, N., and Baron, C. (2002) Detergent extraction identifies different VirB protein subassemblies of the type IV secretion machinery in the membranes of Agrobacterium tumefaciens. Proc Natl Acad Sci USA 99: 11405-11410.
21. Llosa, M., Gomis-Ruth, F.X., Coll, M., and de la Cruz, F. (2002) Bacterial conjugation: a two-step mechanism for DNA transport. Mol Microbiol 45: 1-8.
22. More, M.I., Pohlman, R.F., and Winans, S.C. (1996) Genes encoding the pKM101 conjugal mating pore are negatively regulated by the plasmid-encoded KorA and KorB proteins. J Bacteriol 178: 4392-4399.
23. Nagai, H., Kagan, J.C., Zhu, X., Kahn, R.A., and Roy, C.R. (2002) A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science 295: 679-682.
24. Odenbreit, S., Puls, J., Sedlmaier, B., Gerland, E., Fischer, W., and Haas, R. (2000) Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 287: 1497-1500.
25. Ohashi, N., Zhi, N., Lin, Q., and Rikihisa, Y. (2002) Characterization and transcriptional analysis of gene clusters for a type IV secretion machinery in human granulocytic and monocytic ehrlichiosis agents. Infect Immun 70: 2128-2138.
26. Padmalayam, I., Karem, K., Baumstark, B., and Massung, R. (2000) The gene encoding the 17-kDa antigen of Bartonella henselae is located within a cluster of genes homologous to the virB virulence operon. DNA Cell Biol 19: 377-382.
27. Regnery, R.L., Anderson, B.E., Clarridge, J.E., III, Rodriguez-Barradas, M.C., Jones, D.C., and Carr, J.H. (1992) Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. J Clin Microbiol 30: 265-274.
28. Rivas, S., Bolland, S., Cabezon, E., Goni, F.M., and de la Cruz, F. (1997) TrwD, a protein encoded by the IncW plasmid R388, displays an ATP hydrolase activity essential for bacterial conjugation. J Biol Chem 272: 25583-25590.
29. Sagulenko, E., Sagulenko, V., Chen, J., and Christie, P.J. (2001) Role of Agrobacterium VirB11 ATPase in T-pilus assembly and substrate selection. J Bacteriol 183: 5813-5825.
30. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
31. Schmidt-Eisenlohr, H., Domke, N., and Baron, C. (1999) TraC of IncN plasmid pKM101 associates with membranes and extracellular high-molecular-weight structures in Escherichia coli. J Bacteriol 181: 5563-5571.
32. Schmiederer, M., Arcenas, R., Widen, R., Valkov, N., and Anderson, B. (2001) Intracellular induction of the Bartonella henselae virB operon by human endothelial cells. Infect Immun 69: 6495-6502.
33. Schulein, R., and Dehio, C. (2002) The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection. Mol Microbiol 46: 1053-1067.
34. Schulein, R., Seubert, A., Gille, C., Lanz, C., Hansmann, Y., Piemont, Y., and Dehio, C. (2001) Invasion and persistent intracellular colonization of erythrocytes. A unique parasitic strategy of the emerging pathogen Bartonella. J Exp Med 193: 1077-1086.
35. Seubert, A., Falch, C., Birtles, R.J., Schulein, R., and Dehio, C. (2003) Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector. Plasmid 49: 44-52.
36. Short, J.M., Fernandez, J.M., Sorge, J.A., and Huse, W.D. (1988) Lambda ZAP: a bacteriophage lambda expression vector with in vivo excision properties. Nucleic Acids Res 16: 7583-7600.
37. Staskawicz, B., Dahlbeck, D., Keen, N., and Napoli, C. (1987) Molecular characterization of cloned avirulence genes from race 0 and race 1 of Pseudomonas syringae pv. glycinea. J Bacteriol 169: 5789-5794.
38. Stein, M., Rappuoli, R., and Covacci, A. (2000) Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. Proc Natl Acad Sci USA 97: 1263-1268.
39. Thompson, J.D., Higgins, D.G., and Gibson, T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
40. Thompson, J.D., Gibson, T.J., Plewniak, F., Jeanmougin, F., and Higgins, D.G. (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25: 4876-4882.
41. Valdivia, R.H., and Falkow, S. (1997) Fluorescence-based isolation of bacterial genes expressed within host cells. Science 277: 2007-2011.