Denervation is not a primary cause of prion protein down-regulation occurring in the spinal cord of a transgenic model of amyotrophic lateral sclerosis

Annals of the New York Academy of Sciences

Volumn 973, Issue , 2002, Pages 116-119

  Dupuis, Luc ^a   Rene, Frédérique ^a   Di Scala, Franck ^a   Gonzalez De Aguilar, Jose Luis ^a   De Tapia, Marc ^a   Loeffler, Jean Philippe ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Amyotrophic lateral sclerosis (ALS); Axotomy; Gastrocnemius muscle; Prion protein; PrpC; Sciatic nerve; SOD1; Spinal cord

Indexed keywords

CHOLINERGIC RECEPTOR; COMPLEMENTARY DNA; ISOPROTEIN; MESSENGER RNA; PRION PROTEIN; RECEPTOR SUBUNIT; SUPEROXIDE DISMUTASE; TOLONIUM CHLORIDE;

3' UNTRANSLATED REGION; AMYOTROPHIC LATERAL SCLEROSIS; CELL LINE; CLINICAL FEATURE; CLINICAL OBSERVATION; CONFERENCE PAPER; DENERVATION; DISEASE COURSE; DOWN REGULATION; ENZYME ACTIVITY; GASTROCNEMIUS MUSCLE; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC CODE; GLIOSIS; HINDLIMB; LUMBAR SPINAL CORD; MUSCLE ATROPHY; NERVE FIBER; NERVE FIBER DEGENERATION; NERVE FIBER TRANSECTION; NEUROFILAMENT; NEUROLOGIC DISEASE; NEUROMUSCULAR SYNAPSE; NONHUMAN; PATHOLOGICAL ANATOMY; PROGRESSIVE MUSCULAR DYSTROPHY; SCIATIC NERVE; SPINAL CORD; SYMPTOMATOLOGY; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 0036959457     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04618.x     Document Type: Conference Paper

References (5)

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2. DUPUIS, L., M. DE TAPIA, F. RENE, et al. 2000. Differential screening of mutated SOD1 transgenic mice reveals early up-regulation of a fast axonal transport component in spinal cord motor neurons. Neurobiol. Dis. 7: 274-285.
3. DUPUIS, L., C. MBEBI, J.L. GONZALEZ DE AGUILAR, et al. 2002. Loss of prion protein in a transgenic model of amyotrophic lateral sclerosis. Mol. Cell. Neurosci. 19: 216-224.
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5. MOUILLET-RICHARD, S., M. ERMONVAL, C. CHEBASSIER, et al. 2000. Signal transduction through prion protein. Science 289: 1925-1928.