메뉴 건너뛰기




Volumn 120, Issue 3, 2003, Pages 627-634

Serotonergic dorsal raphe neurons from obese Zucker rats are hyperexcitable

Author keywords

Afterhyperpolarization; Dorsal raphe nucleus; Hyperexcitability; Obesity; Satiety; Serotonin

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DISEASE MODEL; DORSAL RAPHE NUCLEUS; ELECTROPHYSIOLOGY; EXCITATORY JUNCTION POTENTIAL; FEEDING BEHAVIOR; HYPERPOLARIZATION; LEAN BODY WEIGHT; MALE; MOUSE STRAIN; NERVE CONDUCTION; NERVE POTENTIAL; NONHUMAN; OBESITY; PATCH CLAMP; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SEROTONIN RELEASE; SEROTONINERGIC NERVE; SIGNAL TRANSDUCTION;

EID: 0043268826     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(03)00360-9     Document Type: Article
Times cited : (15)

References (30)
  • 1
    • 0022415099 scopus 로고
    • Modulation of a transient outward current in serotonergic neurones by alpha 1-adrenoceptors
    • Aghajanian G.K. Modulation of a transient outward current in serotonergic neurones by alpha 1-adrenoceptors. Nature. 315:1985;501-503.
    • (1985) Nature , vol.315 , pp. 501-503
    • Aghajanian, G.K.1
  • 2
    • 0020076457 scopus 로고
    • Intracellular recordings from serotonergic dorsal raphe neurons: Pacemaker potentials and the effect of LSD
    • Aghajanian G.K., Vandermaelen C.P. Intracellular recordings from serotonergic dorsal raphe neurons pacemaker potentials and the effect of LSD . Brain Res. 238:1982;463-469.
    • (1982) Brain Res , vol.238 , pp. 463-469
    • Aghajanian, G.K.1    Vandermaelen, C.P.2
  • 3
    • 0017705191 scopus 로고
    • System organization of alimentary behavior in the newborn and the developing cat
    • Anokhin P.K., Shuleikina K.V. System organization of alimentary behavior in the newborn and the developing cat. Dev Psychobiol. 10:1977;385-419.
    • (1977) Dev Psychobiol , vol.10 , pp. 385-419
    • Anokhin, P.K.1    Shuleikina, K.V.2
  • 4
    • 0024317840 scopus 로고
    • Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection: Dialysate serotonin reflects neuronal release
    • Auerbach S.B., Minzenberg M.J., Wilkinson L.O. Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection dialysate serotonin reflects neuronal release . Brain Res. 499:1989;281-290.
    • (1989) Brain Res , vol.499 , pp. 281-290
    • Auerbach, S.B.1    Minzenberg, M.J.2    Wilkinson, L.O.3
  • 5
    • 0021958698 scopus 로고
    • Dynamics of pancreatic insulin release in young Zucker rats: A heterozygote effect
    • Blonz E.R., Stern J.S., Curry D.L. Dynamics of pancreatic insulin release in young Zucker rats a heterozygote effect . Am J Physiol. 248:1985;E188-E193.
    • (1985) Am J Physiol , vol.248
    • Blonz, E.R.1    Stern, J.S.2    Curry, D.L.3
  • 6
    • 0023548692 scopus 로고
    • Serotoninergic modulation of the pattern of eating and the profile of hunger-satiety in humans
    • Blundell J.E., Hill A.J. Serotoninergic modulation of the pattern of eating and the profile of hunger-satiety in humans. Int J Obesity. 11:(Suppl 3):1987;141-155.
    • (1987) Int J Obesity , vol.11 , Issue.SUPPL. 3 , pp. 141-155
    • Blundell, J.E.1    Hill, A.J.2
  • 7
    • 0018704826 scopus 로고
    • Onset of genetic obesity in the absence of hyperphagia during the first week of life in the Zucker rat (fa/fa)
    • Boulange A., Planche E., de Gasquet P. Onset of genetic obesity in the absence of hyperphagia during the first week of life in the Zucker rat (fa/fa). J Lipid Res. 20:1979;857-864.
    • (1979) J Lipid Res , vol.20 , pp. 857-864
    • Boulange, A.1    Planche, E.2    De Gasquet, P.3
  • 9
    • 0034615847 scopus 로고    scopus 로고
    • Intracerebroventricular infusion of leptin decreases serotonin transporter binding sites in the frontal cortex of the rat
    • Charnay Y., Cusin I., Vallet P.G., Muzzin P., Rohner-Jeanrenaud F., Bouras C. Intracerebroventricular infusion of leptin decreases serotonin transporter binding sites in the frontal cortex of the rat. Neurosci Lett. 283:2000;89-92.
    • (2000) Neurosci Lett , vol.283 , pp. 89-92
    • Charnay, Y.1    Cusin, I.2    Vallet, P.G.3    Muzzin, P.4    Rohner-Jeanrenaud, F.5    Bouras, C.6
  • 11
    • 0020530552 scopus 로고
    • Passive membrane properties of neurones in the dorsal raphe and periaqueductal gray recorded in vitro
    • Crunelli V., Forda S., Brooks P.A., Wilson K.C., Wise J.C., Kelly J.S. Passive membrane properties of neurones in the dorsal raphe and periaqueductal gray recorded in vitro. Neurosci Lett. 40:1983;263-268.
    • (1983) Neurosci Lett , vol.40 , pp. 263-268
    • Crunelli, V.1    Forda, S.2    Brooks, P.A.3    Wilson, K.C.4    Wise, J.C.5    Kelly, J.S.6
  • 12
    • 0027287741 scopus 로고
    • Differential effects of NE, CLON, and 5-HT on feeding and macronutrient selection in genetically obese (ob/ob) and lean mice
    • Currie P.J. Differential effects of NE, CLON, and 5-HT on feeding and macronutrient selection in genetically obese (ob/ob) and lean mice. Brain Res Bull. 32:1993;133-142.
    • (1993) Brain Res Bull , vol.32 , pp. 133-142
    • Currie, P.J.1
  • 13
    • 0034733883 scopus 로고    scopus 로고
    • Extracellular hypothalamic serotonin levels after dorsal raphe nuclei stimulation of lean (Fa/Fa) and obese (fa/fa) Zucker rats
    • De Fanti B.A., Gavel D.A., Hamilton J.S., Horwitz B.A. Extracellular hypothalamic serotonin levels after dorsal raphe nuclei stimulation of lean (Fa/Fa) and obese (fa/fa) Zucker rats. Brain Res. 869:2000;6-14.
    • (2000) Brain Res , vol.869 , pp. 6-14
    • De Fanti, B.A.1    Gavel, D.A.2    Hamilton, J.S.3    Horwitz, B.A.4
  • 14
    • 0035369074 scopus 로고    scopus 로고
    • Meal-induced changes in extracellular 5-HT in medial hypothalamus of lean (Fa/Fa) and obese (fa/fa) Zucker rats
    • De Fanti B.A., Hamilton J.S., Horwitz B.A. Meal-induced changes in extracellular 5-HT in medial hypothalamus of lean (Fa/Fa) and obese (fa/fa) Zucker rats. Brain Res. 902:2001;164-170.
    • (2001) Brain Res , vol.902 , pp. 164-170
    • De Fanti, B.A.1    Hamilton, J.S.2    Horwitz, B.A.3
  • 15
    • 0029887014 scopus 로고    scopus 로고
    • A subgroup of dorsal raphe serotonergic neurons in the cat is strongly activated during oral-buccal movements
    • Fornal C.A., Metzler C.W., Marrosu F., Ribiero-do-Valle L.E., Jacobs B.L. A subgroup of dorsal raphe serotonergic neurons in the cat is strongly activated during oral-buccal movements. Brain Res. 716:1996;123-133.
    • (1996) Brain Res , vol.716 , pp. 123-133
    • Fornal, C.A.1    Metzler, C.W.2    Marrosu, F.3    Ribiero-do-Valle, L.E.4    Jacobs, B.L.5
  • 16
    • 0021603088 scopus 로고
    • Atlas of serotonergic cell bodies in the cat brainstem: An immunocytochemical analysis
    • Jacobs B.L., Gannon P.J., Azmitia E.C. Atlas of serotonergic cell bodies in the cat brainstem an immunocytochemical analysis . Brain Res Bull. 13:1984;1-31.
    • (1984) Brain Res Bull , vol.13 , pp. 1-31
    • Jacobs, B.L.1    Gannon, P.J.2    Azmitia, E.C.3
  • 17
    • 0032956713 scopus 로고    scopus 로고
    • Regulation of body weight in humans
    • Jéquier E., Tappy L. Regulation of body weight in humans. Physiol Rev. 79:1999;451-480.
    • (1999) Physiol Rev , vol.79 , pp. 451-480
    • Jéquier, E.1    Tappy, L.2
  • 18
    • 0032213142 scopus 로고    scopus 로고
    • Hypothalamic serotonin in control of eating behavior, meal size, and body weight
    • Leibowitz S.F., Alexander J.T. Hypothalamic serotonin in control of eating behavior, meal size, and body weight. Biol Psychiatry. 44:1998;851-864.
    • (1998) Biol Psychiatry , vol.44 , pp. 851-864
    • Leibowitz, S.F.1    Alexander, J.T.2
  • 19
    • 0031684918 scopus 로고    scopus 로고
    • Combined effect of obesity and aging on feeding-induced monoamine release in the rostromedial hypothalamus of the Zucker rat
    • Lemierre S., Rouch C., Nicolaidis S., Orosco M. Combined effect of obesity and aging on feeding-induced monoamine release in the rostromedial hypothalamus of the Zucker rat. Int J Obesity Relat Metab Disord. 22:1998;993-999.
    • (1998) Int J Obesity Relat Metab Disord , vol.22 , pp. 993-999
    • Lemierre, S.1    Rouch, C.2    Nicolaidis, S.3    Orosco, M.4
  • 20
    • 0019459523 scopus 로고
    • Ontogeny of feeding behavior in the Zucker obese rat
    • McLaughlin C.L., Baile C.A. Ontogeny of feeding behavior in the Zucker obese rat. Physiol Behav. 26:1981;607-612.
    • (1981) Physiol Behav , vol.26 , pp. 607-612
    • McLaughlin, C.L.1    Baile, C.A.2
  • 21
    • 0034647947 scopus 로고    scopus 로고
    • Dopamine and serotonin VMN release is related to feeding status in obese and lean Zucker rats
    • Meguid M.M., Fetissov S.O., Blaha V., Yang Z.J. Dopamine and serotonin VMN release is related to feeding status in obese and lean Zucker rats. Neuroreport. 11:2000;2069-2072.
    • (2000) Neuroreport , vol.11 , pp. 2069-2072
    • Meguid, M.M.1    Fetissov, S.O.2    Blaha, V.3    Yang, Z.J.4
  • 22
    • 0022344823 scopus 로고
    • Brown fat thermogenesis and its role in the development of obesity
    • Moore B.J., Horwitz B.A., Stern J.S. Brown fat thermogenesis and its role in the development of obesity. Brain Res Bull. 14:1985;577-583.
    • (1985) Brain Res Bull , vol.14 , pp. 577-583
    • Moore, B.J.1    Horwitz, B.A.2    Stern, J.S.3
  • 23
    • 0016140262 scopus 로고
    • Midbrain raphe neurons: Spontaneous activity and response to light
    • Mosko S.S., Jacobs B.L. Midbrain raphe neurons spontaneous activity and response to light . Physiol Behav. 13:1974;589-593.
    • (1974) Physiol Behav , vol.13 , pp. 589-593
    • Mosko, S.S.1    Jacobs, B.L.2
  • 24
    • 0031721271 scopus 로고    scopus 로고
    • Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
    • Nonogaki K., Strack A.M., Dallman M.F., Tecott L.H. Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat Med. 4:1998;1152-1156.
    • (1998) Nat Med , vol.4 , pp. 1152-1156
    • Nonogaki, K.1    Strack, A.M.2    Dallman, M.F.3    Tecott, L.H.4
  • 25
    • 0037206633 scopus 로고    scopus 로고
    • Adrenergic excitation of serotonergic dorsal raphe neurons is enhanced in genetically obese rats
    • Ohliger-Frerking P., Horowitz J.M., Horwitz B.A. Adrenergic excitation of serotonergic dorsal raphe neurons is enhanced in genetically obese rats. Neurosci Lett. 332:2002;107-110.
    • (2002) Neurosci Lett , vol.332 , pp. 107-110
    • Ohliger-Frerking, P.1    Horowitz, J.M.2    Horwitz, B.A.3
  • 26
    • 0026443992 scopus 로고
    • Spontaneous feeding-related monoaminergic changes in the rostromedial hypothalamus revealed by microdialysis
    • Orosco M., Nicolaidis S. Spontaneous feeding-related monoaminergic changes in the rostromedial hypothalamus revealed by microdialysis. Physiol Behav. 52:1992;1015-1019.
    • (1992) Physiol Behav , vol.52 , pp. 1015-1019
    • Orosco, M.1    Nicolaidis, S.2
  • 27
    • 0022653334 scopus 로고
    • Ontogeny of brain monoamines in lean and obese female Zucker rats
    • Orosco M., Trouvin J.H., Cohen Y., Jacquot C. Ontogeny of brain monoamines in lean and obese female Zucker rats. Physiol Behav. 36:1986;853-856.
    • (1986) Physiol Behav , vol.36 , pp. 853-856
    • Orosco, M.1    Trouvin, J.H.2    Cohen, Y.3    Jacquot, C.4
  • 28
    • 0027952015 scopus 로고
    • Serotonergic activity is depressed in the ventromedial hypothalamic nucleus of 12-day-old obese Zucker rats
    • Routh V.H., Stern J.S., Horwitz B.A. Serotonergic activity is depressed in the ventromedial hypothalamic nucleus of 12-day-old obese Zucker rats. Am J Physiol. 267:1994;R712-R719.
    • (1994) Am J Physiol , vol.267
    • Routh, V.H.1    Stern, J.S.2    Horwitz, B.A.3
  • 29
    • 0025667710 scopus 로고
    • Serotonin release in lateral and medial hypothalamus during feeding and its anticipation
    • Schwartz D.H., Hernandez L., Hoebel B.G. Serotonin release in lateral and medial hypothalamus during feeding and its anticipation. Brain Res Bull. 25:1990;797-802.
    • (1990) Brain Res Bull , vol.25 , pp. 797-802
    • Schwartz, D.H.1    Hernandez, L.2    Hoebel, B.G.3
  • 30
    • 0021023465 scopus 로고
    • Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices
    • Vandermaelen C.P., Aghajanian G.K. Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices. Brain Res. 289:1983;109-119.
    • (1983) Brain Res , vol.289 , pp. 109-119
    • Vandermaelen, C.P.1    Aghajanian, G.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.