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Volumn 102, Issue 4, 2003, Pages 1276-1281

Mithramycin induces fetal hemoglobin production in normal and thalassemic human erythroid precursor cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; BETA ACTIN; BETA GLOBIN; ERYTHROPOIETIN; GAMMA GLOBIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEMOGLOBIN F; HYDROXYUREA; MESSENGER RNA; MITHRAMYCIN;

EID: 0043240257     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-10-3096     Document Type: Article
Times cited : (119)

References (53)
  • 1
    • 0028837699 scopus 로고
    • Novel treatment options in the severe β-globin disorder
    • Rodgers GP, Rachmilewitz EA. Novel treatment options in the severe β-globin disorder. Br J Haematol. 1995;91:263-268.
    • (1995) Br J Haematol , vol.91 , pp. 263-268
    • Rodgers, G.P.1    Rachmilewitz, E.A.2
  • 3
    • 0031712378 scopus 로고    scopus 로고
    • The therapeutic reactivation of fetal hemoglobin
    • Olivieri NF, Weatherall DJ. The therapeutic reactivation of fetal hemoglobin. Hum Mol Genet. 1998; 7:1655-1658.
    • (1998) Hum Mol Genet , vol.7 , pp. 1655-1658
    • Olivieri, N.F.1    Weatherall, D.J.2
  • 4
    • 0031849487 scopus 로고    scopus 로고
    • Elimination of transfusions through induction of fetal hemoglobin synthesis in Cooley's anemia
    • Olivieri NF, Reee DC, Ginder DG, et al. Elimination of transfusions through induction of fetal hemoglobin synthesis in Cooley's anemia. Ann N Y Acad Sci. 1998;850:100-109.
    • (1998) Ann N Y Acad Sci , vol.850 , pp. 100-109
    • Olivieri, N.F.1    Reee, D.C.2    Ginder, D.G.3
  • 6
    • 0031468947 scopus 로고    scopus 로고
    • Pharmacological induction of foetal haemoglobin synthesis in sickle-cell disease
    • Saleh AW, Hillen HF. Pharmacological induction of foetal haemoglobin synthesis in sickle-cell disease. Neth J Med. 1997;51:169-178.
    • (1997) Neth J Med , vol.51 , pp. 169-178
    • Saleh, A.W.1    Hillen, H.F.2
  • 7
    • 0029025475 scopus 로고
    • Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia
    • Investigators of the Multicente Study of Hydroxyurea in Sickle Cell Anemia
    • Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicente Study of Hydroxyurea in Sickle Cell Anemia. N Engl J Med. 1995;332:1317-1322.
    • (1995) N Engl J Med , vol.332 , pp. 1317-1322
    • Charache, S.1    Terrin, M.L.2    Moore, R.D.3
  • 8
    • 0030893396 scopus 로고    scopus 로고
    • Fetal hemoglobin in sickle cell anemia: Determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea
    • Steinberg MH, Lu ZH, Barton FB, Terrin ML, Charache S, Dover GJ. Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea. Blood. 1997;89:1078-1088.
    • (1997) Blood , vol.89 , pp. 1078-1088
    • Steinberg, M.H.1    Lu, Z.H.2    Barton, F.B.3    Terrin, M.L.4    Charache, S.5    Dover, G.J.6
  • 9
    • 0026710710 scopus 로고
    • Increased fetal hemoglobin in patients receiving sodium 4-phenylbutyrate
    • Dover GJ, Brusilow S, Samid D. Increased fetal hemoglobin in patients receiving sodium 4-phenylbutyrate. N Engl J Med. 1992;327:569-570.
    • (1992) N Engl J Med , vol.327 , pp. 569-570
    • Dover, G.J.1    Brusilow, S.2    Samid, D.3
  • 10
    • 0027496417 scopus 로고
    • Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia
    • Fibach E, Prasanna P, Rodgers GP, Samid D. Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia. Blood. 1993;82:2203-2209.
    • (1993) Blood , vol.82 , pp. 2203-2209
    • Fibach, E.1    Prasanna, P.2    Rodgers, G.P.3    Samid, D.4
  • 12
    • 0031822681 scopus 로고    scopus 로고
    • Cellular and molecular effects of a pulse butyrate regimen and new inducers of globin gene expression and hematopoiesis
    • Ikuta T, Atweh G, Boosalis V, et al. Cellular and molecular effects of a pulse butyrate regimen and new inducers of globin gene expression and hematopoiesis. Ann N Y Acad Sci. 1998;850:87-99.
    • (1998) Ann N Y Acad Sci , vol.850 , pp. 87-99
    • Ikuta, T.1    Atweh, G.2    Boosalis, V.3
  • 13
    • 0027078611 scopus 로고
    • A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders
    • Perrine SP, Ginder GD, Faller DV, et al. A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders. N Engl J Med. 1993;328:81-86.
    • (1993) N Engl J Med , vol.328 , pp. 81-86
    • Perrine, S.P.1    Ginder, G.D.2    Faller, D.V.3
  • 14
    • 0032962624 scopus 로고    scopus 로고
    • The DNA-binding drugs mithramycin and chromomycin are powerful inducers of erythroid differentiation of human K562 cells
    • Bianchi N, Osti F, Rutigliano C, et al. The DNA-binding drugs mithramycin and chromomycin are powerful inducers of erythroid differentiation of human K562 cells. Br J Haematol. 1999;104:258-265.
    • (1999) Br J Haematol , vol.104 , pp. 258-265
    • Bianchi, N.1    Osti, F.2    Rutigliano, C.3
  • 15
    • 0034011877 scopus 로고    scopus 로고
    • Induction of erythroid differentiation of human K562 cells by cisplatin analogs
    • Bianchi N, Ongaro F, Chiarabelli C, et al. Induction of erythroid differentiation of human K562 cells by cisplatin analogs. Biochem Pharmacol. 2000;60:31-40.
    • (2000) Biochem Pharmacol , vol.60 , pp. 31-40
    • Bianchi, N.1    Ongaro, F.2    Chiarabelli, C.3
  • 16
    • 0022693818 scopus 로고
    • Design of sequence-specific DNA binding molecules
    • Dervan PB. Design of sequence-specific DNA binding molecules. Science. 1986;232:464-471.
    • (1986) Science , vol.232 , pp. 464-471
    • Dervan, P.B.1
  • 18
    • 0030598375 scopus 로고    scopus 로고
    • Targeting of the Sp1 binding sites of HIV-1 long terminal repeat with chromomycin. Disruption of nuclear factor. DNA complexes and inhibition of in vitro transcription
    • Bianchi N, Passadore M, Rutigliano C, Feriotto G, Mischiati C, Gambari R. Targeting of the Sp1 binding sites of HIV-1 long terminal repeat with chromomycin. Disruption of nuclear factor. DNA complexes and inhibition of in vitro transcription. Biochem Pharmacol. 1996;52:1489-1498.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1489-1498
    • Bianchi, N.1    Passadore, M.2    Rutigliano, C.3    Feriotto, G.4    Mischiati, C.5    Gambari, R.6
  • 19
    • 0032518463 scopus 로고    scopus 로고
    • Modulation of DNA-protein interactions in the P1 and P2 c-myc promoters by two intercalating drugs
    • Vaquero A, Portugal J. Modulation of DNA-protein interactions in the P1 and P2 c-myc promoters by two intercalating drugs. Eur J Biochem. 1998; 251:435-442.
    • (1998) Eur J Biochem , vol.251 , pp. 435-442
    • Vaquero, A.1    Portugal, J.2
  • 20
    • 0024338673 scopus 로고
    • Mithramycin blocks protein binding and function of the SV40 early promoter
    • Ray R, Snyder RC, Thomas S, Koller CA, Miller DM. Mithramycin blocks protein binding and function of the SV40 early promoter. J Clin Invest. 1989;83:2003-2007.
    • (1989) J Clin Invest , vol.83 , pp. 2003-2007
    • Ray, R.1    Snyder, R.C.2    Thomas, S.3    Koller, C.A.4    Miller, D.M.5
  • 21
    • 0025754048 scopus 로고
    • Mithramycin blocks transcriptional initiation of the c-myc P1 and P2 promoters
    • Snyder RC, Ray R, Blume S, Miller DM. Mithramycin blocks transcriptional initiation of the c-myc P1 and P2 promoters. Biochemistry. 1991;30: 4290-4297.
    • (1991) Biochemistry , vol.30 , pp. 4290-4297
    • Snyder, R.C.1    Ray, R.2    Blume, S.3    Miller, D.M.4
  • 22
    • 0028135013 scopus 로고
    • Targeting DNA-binding drugs to sequence-specific transcription factor. DNA complexes. Differential effects of intercalating and minor groove binding drugs
    • Welch JJ, Rauscher FJ III, Beerman TA. Targeting DNA-binding drugs to sequence-specific transcription factor. DNA complexes. Differential effects of intercalating and minor groove binding drugs. J Biol Chem. 1994;269:31051-31058.
    • (1994) J Biol Chem , vol.269 , pp. 31051-31058
    • Welch, J.J.1    Rauscher F.J. III2    Beerman, T.A.3
  • 24
    • 0021933193 scopus 로고
    • Species-specific differences in the toxicity and mutagenicity of the anticancer drugs mithramycin, chromomycin A3, and olivomycin
    • Singh B, Gupta RS. Species-specific differences in the toxicity and mutagenicity of the anticancer drugs mithramycin, chromomycin A3, and olivomycin. Cancer Res. 1985;45:2813-2820.
    • (1985) Cancer Res , vol.45 , pp. 2813-2820
    • Singh, B.1    Gupta, R.S.2
  • 25
    • 0030851551 scopus 로고    scopus 로고
    • A pilot study of alpha-interferon and plicamycin for accelerated phase of chronic myeloid leukemia
    • Dutcher JP, Coletti D, Paietta E, Wiernik PH. A pilot study of alpha-interferon and plicamycin for accelerated phase of chronic myeloid leukemia. Leuk Res. 1997;21:375-380.
    • (1997) Leuk Res , vol.21 , pp. 375-380
    • Dutcher, J.P.1    Coletti, D.2    Paietta, E.3    Wiernik, P.H.4
  • 27
    • 0032758687 scopus 로고    scopus 로고
    • Comparative tolerability of drug therapies for hypercalcaemia of malignancy
    • Zojer N, Keck AV, Pecherstorfer M. Comparative tolerability of drug therapies for hypercalcaemia of malignancy. Drug Saf. 1999;21:389-406.
    • (1999) Drug Saf , vol.21 , pp. 389-406
    • Zojer, N.1    Keck, A.V.2    Pecherstorfer, M.3
  • 28
  • 29
    • 0019365915 scopus 로고
    • Differential expression of the globin genes in human leukemia K562(S) cells induced to differentiate by hemin or butyric acid
    • Cioè L, McNab A, Hubbell HR, Meo P, Curtis P, Rovera G. Differential expression of the globin genes in human leukemia K562(S) cells induced to differentiate by hemin or butyric acid. Cancer Res. 1981;41:237-243.
    • (1981) Cancer Res , vol.41 , pp. 237-243
    • Cioè, L.1    McNab, A.2    Hubbell, H.R.3    Meo, P.4    Curtis, P.5    Rovera, G.6
  • 30
    • 0024581574 scopus 로고
    • Proliferation and maturation of human erythroid progenitors in liquid medium
    • Fibach E, Manor D, Oppenheim A, Rachmilewitz EA. Proliferation and maturation of human erythroid progenitors in liquid medium. Blood. 1989; 73:100-103.
    • (1989) Blood , vol.73 , pp. 100-103
    • Fibach, E.1    Manor, D.2    Oppenheim, A.3    Rachmilewitz, E.A.4
  • 31
    • 0026020709 scopus 로고
    • Growth of human normal erythroid progenitors in liquid culture: A comparison with colony growth in semisolid culture
    • Fibach E, Manor D, Treves A, Rachmilewitz EA. Growth of human normal erythroid progenitors in liquid culture: a comparison with colony growth in semisolid culture. Int J Cell Cloning. 1991;9:57-64.
    • (1991) Int J Cell Cloning , vol.9 , pp. 57-64
    • Fibach, E.1    Manor, D.2    Treves, A.3    Rachmilewitz, E.A.4
  • 32
    • 0034778940 scopus 로고    scopus 로고
    • Cell culture and animal models to screen for promising fetal hemoglobin-stimulating compounds
    • Fibach E. Cell culture and animal models to screen for promising fetal hemoglobin-stimulating compounds. Semin Hematol. 2001;38:374-381.
    • (2001) Semin Hematol , vol.38 , pp. 374-381
    • Fibach, E.1
  • 33
    • 0032407144 scopus 로고    scopus 로고
    • Techniques for studying stimulation of fetal hemoglobin production in human erythroid cultures
    • Fibach E. Techniques for studying stimulation of fetal hemoglobin production in human erythroid cultures. Hemoglobin. 1998;22:445-458.
    • (1998) Hemoglobin , vol.22 , pp. 445-458
    • Fibach, E.1
  • 34
    • 0034066115 scopus 로고    scopus 로고
    • Two-phase liquid culture system models normal human adult erythropoiesis at the molecular level
    • Pope SH, Fibach E, Sun J, Chin K, Rodgers GP. Two-phase liquid culture system models normal human adult erythropoiesis at the molecular level. Eur J Haematol. 2000;64:292-303.
    • (2000) Eur J Haematol , vol.64 , pp. 292-303
    • Pope, S.H.1    Fibach, E.2    Sun, J.3    Chin, K.4    Rodgers, G.P.5
  • 35
    • 0026041652 scopus 로고
    • Diagnosis of thalassemia using cDNA amplification of circulating erythroid cell mRNA with the polymerase chain reaction
    • Huang SZ, Rodgers GP, Zeng FY, Zeng YT, Schechter AN. Diagnosis of thalassemia using cDNA amplification of circulating erythroid cell mRNA with the polymerase chain reaction. Blood. 1991;78:2433-2437.
    • (1991) Blood , vol.78 , pp. 2433-2437
    • Huang, S.Z.1    Rodgers, G.P.2    Zeng, F.Y.3    Zeng, Y.T.4    Schechter, A.N.5
  • 36
    • 0000778479 scopus 로고
    • Extraction, purification and analysis of messenger RNA from eukaryotic cells
    • Nolan C, ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
    • Sambrook J, Fritsch EF, Maniatis T. Extraction, purification and analysis of messenger RNA from eukaryotic cells. In: Nolan C, ed. Molecular Cloning. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1981;7.43-7.45.
    • (1981) Molecular Cloning. 2nd Ed. , pp. 743-745
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 37
    • 0025861818 scopus 로고
    • Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase
    • Holland PM, Abramson RD, Watson R, Gelfand DH. Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc Natl Acad Sci U S A. 1991;88: 7276-7281.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 7276-7281
    • Holland, P.M.1    Abramson, R.D.2    Watson, R.3    Gelfand, D.H.4
  • 38
    • 0028834086 scopus 로고
    • Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization
    • Livak KJ, Flood SJ, Marmaro J, Giusti W, Deetz K. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl. 1995;4:357-362.
    • (1995) PCR Methods Appl , vol.4 , pp. 357-362
    • Livak, K.J.1    Flood, S.J.2    Marmaro, J.3    Giusti, W.4    Deetz, K.5
  • 40
    • 0029964835 scopus 로고    scopus 로고
    • A novel method for real time quantitative RT-PCR
    • Gibson UE, Heid CA, Williams PM. A novel method for real time quantitative RT-PCR. Genome Res. 1996;6:995-1001.
    • (1996) Genome Res , vol.6 , pp. 995-1001
    • Gibson, U.E.1    Heid, C.A.2    Williams, P.M.3
  • 41
    • 0027446929 scopus 로고
    • Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia
    • Fibach E, Burke LP, Schechter AN, Noguchi CT, Rodgers GP. Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia. Blood. 1993;81:1630-1635.
    • (1993) Blood , vol.81 , pp. 1630-1635
    • Fibach, E.1    Burke, L.P.2    Schechter, A.N.3    Noguchi, C.T.4    Rodgers, G.P.5
  • 42
    • 0034817066 scopus 로고    scopus 로고
    • Interaction of antitumor drug, mithramycin, with chromatin
    • Mir MA, Dasgupta D. Interaction of antitumor drug, mithramycin, with chromatin. Biochem Biophys Res Commun. 2001;280:68-74.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 68-74
    • Mir, M.A.1    Dasgupta, D.2
  • 43
    • 0002832678 scopus 로고
    • Antitumor antibiotics and related compounds
    • Perry MC, ed. Baltimore, MD: Williams & Wilkins
    • Riggs CE. Antitumor antibiotics and related compounds. In: Perry MC, ed. The Chemotherapy Source Book. Baltimore, MD: Williams & Wilkins; 1992:340-342.
    • (1992) The Chemotherapy Source Book , pp. 340-342
    • Riggs, C.E.1
  • 44
    • 0021738685 scopus 로고
    • Hepatic toxicity of low doses of mithramycin in hypercalcemia
    • Green L, Donehower RC. Hepatic toxicity of low doses of mithramycin in hypercalcemia. Cancer Treat Rep. 1984;68:1379-1381.
    • (1984) Cancer Treat Rep , vol.68 , pp. 1379-1381
    • Green, L.1    Donehower, R.C.2
  • 45
  • 46
    • 0017053449 scopus 로고
    • Treatment of hypercalcemia associated with osseous metastases
    • Stapleton FB, Luker BP, Linshaw MA. Treatment of hypercalcemia associated with osseous metastases. J Pediatr. 1976;89:1029-1030.
    • (1976) J Pediatr , vol.89 , pp. 1029-1030
    • Stapleton, F.B.1    Luker, B.P.2    Linshaw, M.A.3
  • 47
    • 0022891311 scopus 로고
    • Preliminary observations on the therapy of the myeloid blast phase of chronic granulocytic leukemia with plicamycin and hydroxyurea
    • Koller CA, Miller DM. Preliminary observations on the therapy of the myeloid blast phase of chronic granulocytic leukemia with plicamycin and hydroxyurea. N Engl J Med. 1986;315:1433-1438.
    • (1986) N Engl J Med , vol.315 , pp. 1433-1438
    • Koller, C.A.1    Miller, D.M.2
  • 48
    • 0015104003 scopus 로고
    • Determination of hydroxyurea in mammalian tissues and blood
    • Fabricius E, Rajewsky F. Determination of hydroxyurea in mammalian tissues and blood. Rev Eur Etud Clin Biol. 1971;16:679-683.
    • (1971) Rev Eur Etud Clin Biol , vol.16 , pp. 679-683
    • Fabricius, E.1    Rajewsky, F.2
  • 50
    • 0022550596 scopus 로고
    • Enzyme immunoassay for the quantification of mithramycin using beta-D-galactosidase as a label
    • Fujiwara K, Saita T, Nakashima K, Kitagawa T. Enzyme immunoassay for the quantification of mithramycin using beta-D-galactosidase as a label. Cancer Res. 1986;46:1084-1088.
    • (1986) Cancer Res , vol.46 , pp. 1084-1088
    • Fujiwara, K.1    Saita, T.2    Nakashima, K.3    Kitagawa, T.4
  • 51
    • 0037114756 scopus 로고    scopus 로고
    • Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo
    • Pace BS, White GL, Dover GJ, Boosalis MS, Faller DV, Perrine SP. Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. Blood. 2002;100:4640-4648.
    • (2002) Blood , vol.100 , pp. 4640-4648
    • Pace, B.S.1    White, G.L.2    Dover, G.J.3    Boosalis, M.S.4    Faller, D.V.5    Perrine, S.P.6
  • 52
    • 0037140766 scopus 로고    scopus 로고
    • Rationally designed glycosylated premithramycins: Hybrid aromatic polyketides using genes from three different biosynthetic pathways
    • Trefzer A, Blanco G, Remsing L, et al. Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways. J Am Chem Soc. 2002;124:6056-6062.
    • (2002) J Am Chem Soc , vol.124 , pp. 6056-6062
    • Trefzer, A.1    Blanco, G.2    Remsing, L.3
  • 53
    • 0037181040 scopus 로고    scopus 로고
    • Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway
    • Remsing LL, Garcia-Bernardo J, Gonzalez A, et al. Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway. J Am Chem Soc. 2002;124:1606-1614.
    • (2002) J Am Chem Soc , vol.124 , pp. 1606-1614
    • Remsing, L.L.1    Garcia-Bernardo, J.2    Gonzalez, A.3


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