Increased mitogenic and decreased contractile P2 receptors in smooth muscle cells by shear stress in human vessels with intact endothelium

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 23, Issue 8, 2003, Pages 1370-1376

  Wang, Lingwei ^a   Andersson, Maria ^b   Karlsson, Lena ^b   Watson, Marie Ange ^c   Cousens, Diane J ^c   Jern, Sverker ^b   Erlinge, David ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Gene expression; Purinoceptors; Shear stress; Smooth muscle cells; Vascular remodeling

Indexed keywords

CONTRACTILE PROTEIN; MESSENGER RNA; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; RECEPTOR SUBTYPE;

ARTICLE; BIOMECHANICS; BLOOD FLOW; BLOOD VESSEL TONE; BLOOD VESSEL WALL; CONTROLLED STUDY; CORRELATION ANALYSIS; EXPERIMENTAL MODEL; GENE EXPRESSION REGULATION; HEMODYNAMICS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MITOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; SMOOTH MUSCLE FIBER; UMBILICAL VEIN; WESTERN BLOTTING;

BLOTTING, WESTERN; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, PURINERGIC P2; RNA, MESSENGER; STRESS, MECHANICAL; UMBILICAL VEINS; UP-REGULATION;

EID: 0043235654     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000080350.37408.5A     Document Type: Article

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