Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity

Journal of Medicinal Chemistry

Volumn 46, Issue 17, 2003, Pages 3623-3630

  Querolle, Olivier ^a   Dubois, Joëlle ^a   Thoret, Sylviane ^a   Roussi, Fanny ^a   Montiel Smith, Sara ^b   Guéritte, Françoise ^a   Guénard, Daniel ^a  

^a CNRS   (France)

^b BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

DOCETAXEL; MACROCYCLIC COMPOUND; PACLITAXEL; TAXOID; TUBULIN;

ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; RING CLOSING METATHESIS; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KB CELLS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PACLITAXEL; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; TAXOIDS; TUBULIN;

EID: 0043234178     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030770w     Document Type: Article

References (31)

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