Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II transmembrane, cancer-associated isozyme IX with lipophilic sulfonamides

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 4, 2003, Pages 333-338

  Franchi, Marco ^a   Vullo, Daniela ^a   Gallori, Enzo ^a   Pastorek, Jaromir ^b   Russo, Antonella ^a   Scozzafava, Andrea ^a   Pastorekova, Silvia ^b   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b INSTITUTE OF VIROLOGY   (Slovakia)

Author keywords

Anticancer drug; Carbonic anhydrase; Isozyme I, II, IX; Lipophilic; Sulfonamide

Indexed keywords

5 (N,N DIPHENYLCARBAMOYLAMIDO) 1,3,4 THIADIAZOLE 2 SULFONAMIDE; 5 [4 (DIPHENYLACETAMIDO)PHENYLSUFONYLAMIDO] 1,3,4 THIADIAZOLE 2 SULFONAMIDE; ACETAZOLAMIDE; ACETIC ACID DERIVATIVE; AMINE; ANTINEOPLASTIC AGENT; AROMATIC COMPOUND; BENZENE DERIVATIVE; BRINZOLAMIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CHLORIDE; DICLOFENAMIDE; DORZOLAMIDE; ETHOXZOLAMIDE; HETEROCYCLIC COMPOUND; ISOENZYME; MEMBRANE PROTEIN; METHAZOLAMIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; LIPOPHILICITY; PRIORITY JOURNAL;

ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; HUMANS; ISOENZYMES; NEOPLASM PROTEINS; SULFONAMIDES;

EID: 0043198462     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636031000138778     Document Type: Article

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