The mechanical properties of simple epithelial keratins 8 and 18: Discriminating between interfacial and bulk elasticities

Journal of Structural Biology

Volumn 143, Issue 1, 2003, Pages 45-55

  Yamada, Soichiro ^a   Wirtz, Denis ^a,b   Coulombe, Pierre A ^c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Johns Hopkins University   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Air liquid interface; Intermediate filament; Keratin; Rheology; Simple epithelia

Indexed keywords

KERATIN; KERATIN 18; KERATIN 8; PHOSPHOLIPID; POLYMER; UNCLASSIFIED DRUG; VIMENTIN;

ARTICLE; CYTOPLASM; ELASTICITY; ELECTRON MICROSCOPY; EPITHELIUM; FLOW KINETICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; VISCOELASTICITY;

EID: 0043169526     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1047-8477(03)00101-1     Document Type: Article

References (42)

1. Baribault H., Price J., Miyai K., Oshima R.G. Mid-gestational lethality in mice lacking keratin 8. Genes Dev. 7(7A):1993;1191-1202.
2. Coulombe P.A., Hutton M.E., Vassar R., Fuchs E. A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases. J. Cell Biol. 115(6):1991;1661-1674.
3. Coulombe P.A., Bousquet O., Ma L., Yamada S., Wirtz D. The 'ins' and 'outs' of intermediate filament organization. Trends Cell Biol. 10:2000;420-428.
4. Coulombe P.A., Fuchs E. Elucidating the early stages of keratin filament assembly. J. Cell Biol. 111(1):1990;153-169.
5. Coulombe P.A., Omary M.B. 'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments. Curr. Opin. Cell Biol. 14(1):2002;110-122.
6. Doi M., Edwards S.F. The theory of polymer dynamics. 1986;Clarendon Press, Oxford.
7. Gittes F., MacKintosh F.C. Dynamic shear modulus of a semiflexible polymer network. Phys. Rev. E. 58:1998;R1241-R1244.
8. Graham D.E., Phillips M.C. Proteins at liquid interfaces. 5. Shear properties. J. Coll. Int. Sci. 76:1980;240-250.
9. Hesse M., Franz T., Tamai Y., Taketo M.M., Magin T.M. Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality. Embo. J. 19(19):2000;5060-5070.
10. Hinner B., Tempel M., Sackmann E., Kroy K., Frey E. Entanglement, elasticity, and viscous relaxation of actin solutions. Phys. Rev. Lett. 81:1998;2614-2617.
11. Janmey P.A., Euteneuer U., Traub P., Schliwa M. Viscoelastic properties of vimentin compared with other filamentous biopolymer networks. J. Cell Biol. 113(113):1991;155-160.
12. Ku N.O., Wright T.L., Terrault N.A., Gish R., Omary M.B. Mutation of human keratin 18 in association with cryptogenic cirrhosis. J. Clin. Invest. 99(1):1997;19-23.
13. Ku N.O., Michie S., Oshima R.G., Omary M.B. Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J. Cell Biol. 131(5):1995;1303-1314.
14. Leterrier J.F., Kas J., Hartwig J., Vegners R., Janmey P.A. Mechanical effects of neurofilament cross-bridges - Modulation by phosphorylation, lipids, and interactions with F-actin. J. Biol. Chem. 271:1996;15687-15694.
15. Lloyd C., Yu Q.C., Cheng J., Turksen K., Degenstein L., Hutton E., Fuchs E. The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14. J. Cell Biol. 129(5):1995;1329-1344.
16. Loranger A., Duclos S., Grenier A., Price J., Wilson-Heiner M., Baribault H., Marceau N. Simple epithelium keratins are required for maintenance of hepatocyte integrity. Am. J. Pathol. 151(6):1997;1673-1683.
17. Ma L., Xu J., Coulombe P.A., Wirtz D. Epidermal keratin suspensions have unique micromechanical properties. J. Biol. Chem. 274:1999;19145-19151.
18. Ma L., Yamada S., Wirtz D., Coulombe P.A. A hot-spot mutation alters the mechanical properties of keratin filament networks. Nat. Cell Biol. 3:2001;503-506.
19. Mackie A.R., Gunning A.P., Wilde P.J., Morris V.J. Orogenic displacement of protein from the air/water interface by competitive adsorption. J. Coll. Int. Sci. 1999.
20. Macosko C.W. Rheology: Principles, measurements, and applications. 1994;VCH Publishers, New York.
21. Magin T.M. Lessons from keratin transgenic and knock-out mice. Harris J.R., Herrmann H. Subcellular Biochemistry: Intermediate Filaments. 1998;141-165 Plenum Press, New York.
22. Magin T.M., Schroder R., Leitgeb S., Wanninger F., Zatloukal K., Grund C., Melton D.W. Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates. J. Cell Biol. 140(6):1998;1441-1451.
23. Mason T.G., Dhople A., Wirtz D. Linear viscoelastic moduli of concentrated DNA solutions. Macromolecules. 31:1998;3600-3603.
24. McCormick M.B., Coulombe P.A., Fuchs E. Sorting out IF networks: consequences of domain swapping on IF recognition and assembly. J. Cell Biol. 113(5):1991;1111-1124.
25. Moll R., Franke W.W., Schiller D.L., Geiger B., Krepler R. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. (Review) Cell. 31(1):1982;11-24.
26. Morse D.C. Viscoelasticity of concentrated isotropic solutions of semiflexible polymers. 1. Model and stress tensor. Macromolecules. 31:1998;7030-7043.
27. Muller O., Gaub H., Barmann M., Sackmann E. Viscoelastic properties of sterically and chemically cross-linked actin networks in the dilute and semidilute regime: measurements by an osscilatting disk rheometer. Macromolecules. 24:1991;3111-3120.
28. Muller O., Gaub H.E., Barmann M., Sackmann E. Viscoelastic moduli of sterically and chemically cross-linked actin networks in the dilute regime - Measurements by an oscillating disk rheometer. Macromolecules. 24:1991;3111-3120.
29. O'Guin W.M., Schermer A., Lynch M., Sun T.-T. Differentiation-specific expression of keratin pairs. Goldman R.D., Steinert P.M. Cellular and Molecular Biology of Intermediate Filaments. 1990;301-333 Plenum Press, New York.
30. Omary M.B., Ku N.O. Intermediate filament proteins of the liver: emerging disease association and functions. Hepatology. 25(5):1997;1043-1048.
31. Palmer A., Xu J., Kuo S.C., Wirtz D. Diffusing wave spectroscopy microrheology of actin filament networks. Biophys. J. 76:1999;1063-1071.
32. Peters B., Kirfel J., Bussow H., Vidal M., Magin T.M. Complete cytolysis and neonatal lethality in keratin knock-out mice reveals its fundamental role in skin integrity and in epidermolysis bullosa simplex. Mol. Biol. Cell. 12:2001;1775-1789.
33. Sato M., Leimbach G., Schwarz W.H., Pollard T.D. Mechanical properties of actin. J. Biol. Chem. 260:1985;8585-8592.
34. Sato M., Schwarz W.H., Pollard T.D. Dependence of the mechanical properties of actin/α-actinin gels on deformation rate. Nature. 325:1987;828-830.
35. Tamai Y., Ishikawa T., Bosl M.R., Mori M., Nozaki M., Baribault H., Oshima R.G., Taketo M.M. Cytokeratins 8 and 19 in the mouse placental development. J. Cell Biol. 151(3):2000;563-572.
36. Traub P., Perides G., Kuhn S., Scherbarth A. Efficient interaction of nonpolar lipids with intermediate filaments of the vimentin type. Eur. J. Cell. Biol. 43:1987;55-64.
37. Tseng Y., Wirtz D. Mechanics and multiple-particle tracking microhetrogeneity of α-actinin-cross-linked actin filament networks. Biophys. J. 81:2001;1643-1656.
38. Tseng Y., Fedorov E., McCaffery J.M., Almo S.C., Wirtz D. Micromechanics and microstructure of actin filament networks in the presence of the actin-bundling protein human fascin: a comparison with α-actinin. J. Mol. Biol. 310:2001;351-366.
39. Vassar R., Coulombe P.A., Degenstein L., Albers K., Fuchs E. Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell. 64(2):1991;365-380.
40. Xu J., Schwarz W.H., Kas J., Janmey P.J., Pollard T.D. Mechanical properties of actin filament networks depend on preparation, polymerization conditions, and storage of actin monomers. Biophys. J. 74:1998;2731-2740.
41. Xu J., Tseng Y., Wirtz D. Strain-hardening of actin filament networks - Regulation by the dynamic crosslinking protein α-actinin. J. Biol. Chem. 275:2000;35886-35892.
42. Yamada S., Wirtz D., Coulombe P.A. Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol. Biol. Cell. 13(1):2002;382-391.