The crystal structure of mitochondrial cytochrome bc1 in complex with famoxadone: The role of aromatic-aromatic interaction in inhibition

Biochemistry

Volumn 41, Issue 39, 2002, Pages 11692-11702

  Gao, Xiugong ^a   Wen, Xiaolin ^b   Yu, ChangAn ^b   Esser, Lothar ^a   Tsao, Scott ^b   Quinn, Byron ^b   Zhang, Li ^b   Yu, Linda ^b   Xia, Di ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RESPIRATION;

CRYSTAL STRUCTURE; ENZYME INHIBITION; FUNGICIDES; MUTAGENESIS; OPTIMIZATION; PIGMENTS; PROTEINS;

BIOCHEMISTRY;

UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CHEMICAL COMPOSITION; CHEMICAL INTERACTION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON TRANSPORT; HYDROPHOBICITY; INHIBITION KINETICS; MITOCHONDRIAL RESPIRATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEROZOIC; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME B GROUP; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX III; ENZYME INHIBITORS; HYDROQUINONES; INHIBITORY CONCENTRATION 50; MACROMOLECULAR SUBSTANCES; METHACRYLATES; MITOCHONDRIA, HEART; MOLECULAR SEQUENCE DATA; OXAZOLES; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS;

ANIMALIA;

EID: 0036786230     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026252p     Document Type: Article

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