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Volumn 1628, Issue 3, 2003, Pages 147-155

Estrogen receptor activation function 2 (AF-2) is essential for hormone-dependent transactivation and cell transformation induced by a v-Jun DNA binding domain-estrogen receptor chimera

Author keywords

AF 2 domain; Cell transformation; Estrogen receptor; Transcription; v Jun

Indexed keywords

ACTIVATION FUNCTION 2; ESTRADIOL; ESTROGEN RECEPTOR; PROTEIN; PROTEIN V JUN; UNCLASSIFIED DRUG;

EID: 0043157871     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(03)00136-2     Document Type: Article
Times cited : (4)

References (32)
  • 2
    • 0025059554 scopus 로고
    • Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences
    • Bos T.J., Monteclaro F.S., Mitsunobu F., Ball A.R. Jr., Chang C.H., Nishimura T., Vogt P.K. Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences. Genes Dev. 4:1990;1677-1687.
    • (1990) Genes Dev. , vol.4 , pp. 1677-1687
    • Bos, T.J.1    Monteclaro, F.S.2    Mitsunobu, F.3    Ball A.R., Jr.4    Chang, C.H.5    Nishimura, T.6    Vogt, P.K.7
  • 3
    • 11944254582 scopus 로고
    • C-Jun causes focus formation and anchorage-independent growth in culture but is non-tumorigenic
    • Wong W.Y., Havarstein L.S., Morgan I.M., Vogt P.K. c-Jun causes focus formation and anchorage-independent growth in culture but is non-tumorigenic. Oncogene. 7:1992;2077-2080.
    • (1992) Oncogene , vol.7 , pp. 2077-2080
    • Wong, W.Y.1    Havarstein, L.S.2    Morgan, I.M.3    Vogt, P.K.4
  • 4
    • 0030970725 scopus 로고    scopus 로고
    • Transformation by v-Jun prevents cell cycle exit and promotes apoptosis in the absence of serum growth factors
    • Clark W., Gillespie D.A. Transformation by v-Jun prevents cell cycle exit and promotes apoptosis in the absence of serum growth factors. Cell Growth Differ. 8:1997;371-380.
    • (1997) Cell Growth Differ. , vol.8 , pp. 371-380
    • Clark, W.1    Gillespie, D.A.2
  • 5
    • 0034100567 scopus 로고    scopus 로고
    • V-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity
    • Clark W., Black E.J., MacLaren A., Kruse U., LaThangue N., Vogt P.K., Gillespie D.A. v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity. Mol. Cell. Biol. 20:2000;2529-2542.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2529-2542
    • Clark, W.1    Black, E.J.2    MacLaren, A.3    Kruse, U.4    LaThangue, N.5    Vogt, P.K.6    Gillespie, D.A.7
  • 6
    • 0032481145 scopus 로고    scopus 로고
    • Structure and transcriptional regulation of BKJ, a novel AP-1 target gene activated during jun- or fos-induced fibroblast transformation
    • Hartl M., Bister K. Structure and transcriptional regulation of BKJ, a novel AP-1 target gene activated during jun- or fos-induced fibroblast transformation. Oncogene. 17:1998;2901-2913.
    • (1998) Oncogene , vol.17 , pp. 2901-2913
    • Hartl, M.1    Bister, K.2
  • 7
    • 0031818607 scopus 로고    scopus 로고
    • V-Jun represses c-jun proto-oncogene expression in vivo through a 12-O-tetradecanoylphorbol-13-acetate-responsive element in the proximal gene promoter
    • Hussain S., Kilbey A., Gillespie D.A. v-Jun represses c-jun proto-oncogene expression in vivo through a 12-O-tetradecanoylphorbol-13-acetate-responsive element in the proximal gene promoter. Cell Growth Differ. 9:1998;677-686.
    • (1998) Cell Growth Differ. , vol.9 , pp. 677-686
    • Hussain, S.1    Kilbey, A.2    Gillespie, D.A.3
  • 8
    • 0033545940 scopus 로고    scopus 로고
    • Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation
    • Fu S., Bottoli I., Goller M., Vogt P.K. Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation. Proc. Natl. Acad. Sci. U. S. A. 96:1999;5716-5721.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 5716-5721
    • Fu, S.1    Bottoli, I.2    Goller, M.3    Vogt, P.K.4
  • 9
    • 0035923498 scopus 로고    scopus 로고
    • JAC, a direct target of oncogenic transcription factor Jun, is involved in cell transformation and tumorigenesis
    • Hartl M., Reiter F., Bader A.G., Castellazzi M., Bister K. JAC, a direct target of oncogenic transcription factor Jun, is involved in cell transformation and tumorigenesis. Proc. Natl. Acad. Sci. U. S. A. 98:2001;13601-13606.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 13601-13606
    • Hartl, M.1    Reiter, F.2    Bader, A.G.3    Castellazzi, M.4    Bister, K.5
  • 10
    • 0035829741 scopus 로고    scopus 로고
    • TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1)
    • Bader A.G., Schneider M.L., Bister K., Hartl M. TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1). Oncogene. 20:2001;7524-7535.
    • (2001) Oncogene , vol.20 , pp. 7524-7535
    • Bader, A.G.1    Schneider, M.L.2    Bister, K.3    Hartl, M.4
  • 11
    • 0035843180 scopus 로고    scopus 로고
    • Expression of a down-regulated target, SSeCKS, reverses v-Jun-induced transformation of 10 T1/2 murine fibroblasts
    • Cohen S.B., Waha A., Gelman I.H., Vogt P.K. Expression of a down-regulated target, SSeCKS, reverses v-Jun-induced transformation of 10 T1/2 murine fibroblasts. Oncogene. 20:2001;141-146.
    • (2001) Oncogene , vol.20 , pp. 141-146
    • Cohen, S.B.1    Waha, A.2    Gelman, I.H.3    Vogt, P.K.4
  • 12
    • 0034732343 scopus 로고    scopus 로고
    • Down-regulation of the extracellular matrix protein SPARC in vSrc- and vJun-transformed chick embryo fibroblasts contributes to tumor formation in vivo
    • Vial E., Castellazzi M. Down-regulation of the extracellular matrix protein SPARC in vSrc- and vJun-transformed chick embryo fibroblasts contributes to tumor formation in vivo. Oncogene. 19:2000;1772-1782.
    • (2000) Oncogene , vol.19 , pp. 1772-1782
    • Vial, E.1    Castellazzi, M.2
  • 13
    • 0035971506 scopus 로고    scopus 로고
    • Jun, the oncoprotein
    • Vogt P.K. Jun, the oncoprotein. Oncogene. 20:2001;2365-2377.
    • (2001) Oncogene , vol.20 , pp. 2365-2377
    • Vogt, P.K.1
  • 14
    • 0030781383 scopus 로고    scopus 로고
    • Hormone-regulatable neoplastic transformation induced by a Jun-estrogen receptor chimera
    • Kruse U., Iacovoni J.S., Goller M.E., Vogt P.K. Hormone-regulatable neoplastic transformation induced by a Jun-estrogen receptor chimera. Proc. Natl. Acad. Sci. U. S. A. 94:1997;12396-12400.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 12396-12400
    • Kruse, U.1    Iacovoni, J.S.2    Goller, M.E.3    Vogt, P.K.4
  • 15
    • 0023789310 scopus 로고
    • A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor
    • Picard D., Salser S.J., Yamamoto K.R. A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor. Cell. 54:1988;1073-1080.
    • (1988) Cell , vol.54 , pp. 1073-1080
    • Picard, D.1    Salser, S.J.2    Yamamoto, K.R.3
  • 16
    • 0023712331 scopus 로고
    • The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function
    • Webster N.J., Green S., Jin J.R., Chambon P. The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell. 54:1988;199-207.
    • (1988) Cell , vol.54 , pp. 199-207
    • Webster, N.J.1    Green, S.2    Jin, J.R.3    Chambon, P.4
  • 17
    • 0029670092 scopus 로고    scopus 로고
    • The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions
    • Fialka I., Schwarz H., Reichmann E., Oft M., Busslinger M., Beug H. The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions. J. Cell Biol. 132:1996;1115-1132.
    • (1996) J. Cell Biol. , vol.132 , pp. 1115-1132
    • Fialka, I.1    Schwarz, H.2    Reichmann, E.3    Oft, M.4    Busslinger, M.5    Beug, H.6
  • 18
    • 0029055767 scopus 로고
    • Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera
    • Francis M.K., Phinney D.G., Ryder K. Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera. J. Biol. Chem. 270:1995;11502-11513.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11502-11513
    • Francis, M.K.1    Phinney, D.G.2    Ryder, K.3
  • 19
    • 0029976003 scopus 로고    scopus 로고
    • The inhibitory activity of a transdominant c-jun mutant fused to the ligand binding domain of the estrogen receptor
    • Kim S., Brown P.H., Birrer M.J. The inhibitory activity of a transdominant c-jun mutant fused to the ligand binding domain of the estrogen receptor. Oncogene. 12:1996;1043-1053.
    • (1996) Oncogene , vol.12 , pp. 1043-1053
    • Kim, S.1    Brown, P.H.2    Birrer, M.J.3
  • 20
    • 0026583055 scopus 로고
    • Transformation by Jun: Requirement for leucine zipper, basic region and transactivation domain and enhancement by Fos
    • Morgan I.M., Ransone L.J., Bos T.J., Verma I.M., Vogt P.K. Transformation by Jun: requirement for leucine zipper, basic region and transactivation domain and enhancement by Fos. Oncogene. 7:1992;1119-1125.
    • (1992) Oncogene , vol.7 , pp. 1119-1125
    • Morgan, I.M.1    Ransone, L.J.2    Bos, T.J.3    Verma, I.M.4    Vogt, P.K.5
  • 21
    • 0029984823 scopus 로고    scopus 로고
    • The v-Jun oncoprotein replaces p39 c-Jun as the predominant AP-1 constituent in ASV17-transformed fibroblasts: Implications for SAPK/ JNK-mediated signal transduction
    • Kilbey A., Black E.J., Unlu M., Gillespie D.A. The v-Jun oncoprotein replaces p39 c-Jun as the predominant AP-1 constituent in ASV17-transformed fibroblasts: implications for SAPK/JNK-mediated signal transduction. Oncogene. 12:1996;2409-2418.
    • (1996) Oncogene , vol.12 , pp. 2409-2418
    • Kilbey, A.1    Black, E.J.2    Unlu, M.3    Gillespie, D.A.4
  • 22
    • 0032518334 scopus 로고    scopus 로고
    • An oncogenic mutation uncouples the v-Jun oncoprotein from positive regulation by the SAPK/JNK pathway in vivo
    • May G.H., Funk M., Black E.J., Clark W., Hussain S., Woodgett J.R., Gillespie D.A. An oncogenic mutation uncouples the v-Jun oncoprotein from positive regulation by the SAPK/JNK pathway in vivo. Curr. Biol. 8:1998;117-120.
    • (1998) Curr. Biol. , vol.8 , pp. 117-120
    • May, G.H.1    Funk, M.2    Black, E.J.3    Clark, W.4    Hussain, S.5    Woodgett, J.R.6    Gillespie, D.A.7
  • 23
    • 0034699348 scopus 로고    scopus 로고
    • Transient deactivation of ERK signalling is sufficient for stable entry into G0 in primary avian fibroblasts
    • Black E.J., Clark W., Gillespie D.A. Transient deactivation of ERK signalling is sufficient for stable entry into G0 in primary avian fibroblasts. Curr. Biol. 10:2000;1119-1122.
    • (2000) Curr. Biol. , vol.10 , pp. 1119-1122
    • Black, E.J.1    Clark, W.2    Gillespie, D.A.3
  • 24
    • 0023607522 scopus 로고
    • Characterization of cellular proteins recognizing the HIV enhancer using a microscale DNA-affinity precipitation assay
    • Franza B.R. Jr., Josephs S.F., Gilman M.Z., Ryan W., Clarkson B. Characterization of cellular proteins recognizing the HIV enhancer using a microscale DNA-affinity precipitation assay. Nature. 330:1987;391-395.
    • (1987) Nature , vol.330 , pp. 391-395
    • Franza B.R., Jr.1    Josephs, S.F.2    Gilman, M.Z.3    Ryan, W.4    Clarkson, B.5
  • 25
    • 0026600841 scopus 로고
    • Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors
    • Danielian P.S., White R., Lees J.A., Parker M.G. Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J. 11:1992;1025-1033.
    • (1992) EMBO J. , vol.11 , pp. 1025-1033
    • Danielian, P.S.1    White, R.2    Lees, J.A.3    Parker, M.G.4
  • 26
    • 0032545508 scopus 로고    scopus 로고
    • Mutations in the AF-2/hormone-binding domain of the chimeric activator GAL4.estrogen receptor.VP16 inhibit hormone-dependent transcriptional activation and chromatin remodeling in yeast
    • Stafford G.A., Morse R.H. Mutations in the AF-2/hormone-binding domain of the chimeric activator GAL4.estrogen receptor.VP16 inhibit hormone-dependent transcriptional activation and chromatin remodeling in yeast. J. Biol. Chem. 273:1998;34240-34246.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34240-34246
    • Stafford, G.A.1    Morse, R.H.2
  • 27
    • 0029012163 scopus 로고
    • Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha
    • Bourguet W., Ruff M., Chambon P., Gronemeyer H., Moras D. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature. 375:1995;377-382.
    • (1995) Nature , vol.375 , pp. 377-382
    • Bourguet, W.1    Ruff, M.2    Chambon, P.3    Gronemeyer, H.4    Moras, D.5
  • 28
    • 0029643780 scopus 로고
    • Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid
    • Renaud J.P., Rochel N., Ruff M., Vivat V., Chambon P., Gronemeyer H., Moras D. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature. 378:1995;681-689.
    • (1995) Nature , vol.378 , pp. 681-689
    • Renaud, J.P.1    Rochel, N.2    Ruff, M.3    Vivat, V.4    Chambon, P.5    Gronemeyer, H.6    Moras, D.7
  • 29
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau A.K., Barstad D., Loria P.M., Cheng L., Kushner P.J., Agard D.A., Greene G.L. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell. 95:1998;927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 31
    • 0030950531 scopus 로고    scopus 로고
    • AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors
    • Henttu P.M., Kalkhoven E., Parker M.G. AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors. Mol. Cell. Biol. 17:1997;1832-1839.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1832-1839
    • Henttu, P.M.1    Kalkhoven, E.2    Parker, M.G.3
  • 32
    • 0029585553 scopus 로고
    • Stimulation of c-Jun activity by CBP: C-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro
    • Bannister A.J., Oehler T., Wilhelm D., Angel P., Kouzarides T. Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene. 11:1995;2509-2514.
    • (1995) Oncogene , vol.11 , pp. 2509-2514
    • Bannister, A.J.1    Oehler, T.2    Wilhelm, D.3    Angel, P.4    Kouzarides, T.5


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