Theoretical examination of Mg2+-mediated hydrolysis of a phosphodiester linkage as proposed for the hammerhead ribozyme

Journal of the American Chemical Society

Volumn 125, Issue 32, 2003, Pages 9861-9867

  Torres, Rhonda A ^a   Himo, Fahmi ^a,c   Bruice, Thomas C ^b   Noodleman, Louis ^a   Lovell, Timothy ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ESTERS; MAGNESIUM COMPOUNDS; PROTONS; REACTION KINETICS; RNA;

RIBOZYMES;

HYDROLYSIS;

BASE; ESTER DERIVATIVE; HYDROXIDE; LEWIS ACID; MAGNESIUM ION; METAL ION; PHOSPHORUS DERIVATIVE; PROTON; RIBOZYME; WATER;

ARTICLE; CALCULATION; CATALYSIS; CHEMICAL BOND; DENSITY; GAS; GEOMETRY; HYBRID; HYDROLYSIS; KINETICS; METAL BINDING; MOLECULE; PHASE TRANSITION; PREDICTION; PROTON TRANSPORT; REACTION ANALYSIS; THEORETICAL STUDY;

HYDROLYSIS; KINETICS; MAGNESIUM; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHORIC ACID ESTERS; RNA, CATALYTIC; THERMODYNAMICS;

EID: 0043127005     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja021451h     Document Type: Article

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