A cell-based assay for screening the uridine 5′-diphosphate-glucuronosyltransferase 1A inhibitory potential of new chemical entities

Analytical Biochemistry

Volumn 320, Issue 2, 2003, Pages 310-312

  Padrós, Jaime ^a   Chun, Donald ^a   Chen, Liangfu ^a   Rigolli, Pierre ^a   Flarakos, Themis ^a   Jurima Romet, Mallé ^a  

^a MDS Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY;

CELL-BASED ASSAYS; DIPHOSPHATES; NEW CHEMICAL ENTITIES;

CHEMISTRY;

AMPHOTERICIN B; BILIRUBIN; DEXAMETHASONE; DIMETHYL SULFOXIDE; ETHINYLESTRADIOL; GENTAMICIN; GLUCURONOSYLTRANSFERASE; NEW DRUG; PARACETAMOL; PROPOFOL; SILYMARIN; URIDINE DIPHOSPHATE; XENOBIOTIC AGENT;

ANALYTIC METHOD; ARTICLE; CELL ASSAY; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; CULTURE MEDIUM; DILUTION; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FILTRATION; GLUCURONIDATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; LIQUID CHROMATOGRAPHY; LIVER CELL; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

EID: 0043123207     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(03)00382-8     Document Type: Article

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