Detection of apoptotic cells in intestines from horses with and without gastrointestinal tract disease

American Journal of Veterinary Research

Volumn 64, Issue 8, 2003, Pages 982-988

  Rowe, Emma L ^a   White, Nathaniel A ^a   Buechner Maxwell, Virginia ^b   Robertson, John L ^b   Ward, Daniel L ^b  

^a MARION DUPONT SCOTT EQUINE MEDICAL CENTER   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EOSIN; HEMATOXYLIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPSY; CELL COUNT; CELL DAMAGE; CELL NUCLEUS; CONTROLLED STUDY; DISEASE ASSOCIATION; EUTHANASIA; GASTROINTESTINAL DISEASE; HISTOCHEMISTRY; HISTOPATHOLOGY; HORSE DISEASE; INTESTINE CELL; INTESTINE DISTENSION; INTESTINE FUNCTION; INTESTINE ISCHEMIA; INTESTINE MUCOSA; INTESTINE MUSCLE; INTESTINE OBSTRUCTION; INTESTINE SURGERY; NICK END LABELING; NONHUMAN; SEROSA; SMALL INTESTINE OBSTRUCTION; STRANGULATION; TISSUE SECTION;

ANIMALS; APOPTOSIS; HORSE DISEASES; HORSES; INTESTINAL OBSTRUCTION; INTESTINES; MUSCLE, SMOOTH;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 0043123205     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2003.64.982     Document Type: Article

References (43)

1. MacDonald MH, Pascoe JR, Stover SM, et al. Survival after small intestine resection and anastomosis in horses. Vet Surg 1989;18:415-423.
2. Pascoe PJ, McDonnell WN, Trim CM. Mortality rates and associated factors in equine colic operations - a retrospective study of 341 operations. Can Vet J 1983;24:76-85.
3. White NA, Moore JN, Cowgill LM, et al. Epizootiology and risk factors in equine colic at university hospitals, in Proceedings. 2nd Equine Colic Res Symp 1986;26-29.
4. Freeman DE, Hammock PG, Baker GJ, et al. Short and long term survival and prevalence of postoperative ileus after small intestinal surgery in the horse. Equine Vet J Suppl 2000;32:42-51.
5. Kooreman K, Babbs C, Fessler J. Effect of ischemia and reperfusion on oxidative processes in the large colon and jejunum of horses. Am J Vet Res 1998;59:340-346.
6. Dabareiner RM, Snyder JR, White NA, et al. Microvascular permeability and endothelial cell morphology associated with low-flow ischemia/reperfusion injury in the equine jejunum. Am J Vet Res 1995;56:639-648.
7. Dabareiner RM, Sullins KE, White NA, et al. Serosal injury in the equine jejunum and ascending colon after ischemia-reperfusion or intraluminal distention and decompression. Vet Surg 2001;30:114-125.
8. White NA. Pathophysiology and principles of therapy: pathophysiology of obstruction, strangulation and strangulation/obstruction ischemia. In: Colahan PT, Mayhew IG, Merritt AJ, et al, eds. Equine medicine and surgery. Goleta, Calif: American Veterinary Publications, 1990;590-602.
9. Shah KA, Shurey S, Green CJ. Characterization of apoptosis; in intestinal ischaemia-reperfusion injury - a light and electron microscopic study. Int J Exp Pathol 1997;78:355-363.
10. Iwata A, Harlan JM, Vedder NB, et al. The caspase inhibitor z-VAD is more effective than CD18 adhesion blockade in reducing muscle ischemia-reperfusion injury: implication for clinical trials. Blood 2002;100:2077-2080.
11. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456-1462.
12. Sun Z, Wang X, Wallen R, et al. The influence of apoptosis on intestinal barrier integrity in rats. Scand J Gastroenterol 1998;33:415-422.
13. Ina K, Itoh J, Fukushima K, et al. Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl/Bax mucosal imbalance. J Immunol 1999;163:1081-1090.
14. Lechner O, Wiegers GJ, Oliveira-Dos-Santos AJ, et al. Glucocorticoid production in the murine thymus. Eur J Immunol 2000; 30:337-346.
15. Jacysyn JF. Conde-Moscatelli M, Barrichello CR, et al. Thymic epithelial cells mediate a Bcl-2-independent protection of single-positive thymocytes from dexamethasone-induced apoptosis. Exp Cell Res 2002;272:119-126.
16. Ishii T, Nakamura M, Yagi H, et al. Glucocorticoid-induced thymocyte death in the murine thymus: the effect at later stages. Arch Histol Cytol 1997;60:65-78.
17. Brenner C, Kroemer G. Apoptosis. Mitochondria - the death signal integrators. Science 2000;289:1150-1151.
18. Gavrieli Y, Sherman Y, Ben Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
19. Sgone R, Boeck G, Dietrich H, et al. Simultaneous determination of cell surface antigens and apoptosis. Trends Genet 1994;10:41-42.
20. Gold R. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing translation techniques. Lab Invest 1994;71:219.
21. Perry SW, Epstein LG, Harris AG. Simultaneous in situ detection of apoptosis and necrosis in monolayer cultures by TUNEL and trypan blue staining. Biotechniques 1997;22:1102.
22. Gorczyca W, Gong J, Darzynkiewicz Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotideyl transferase and nick translation assays. Cancer Res 1993; 53:1945-1951.
23. Davison FD, Groves M, Scaravilli F. The effects of formalin fixation on the detection of apoptosis in human brain by in situ end-labelling of DNA. Histochem J 1995;27:983-988.
24. Kroemer G. Mitochondrial control of apoptosis: an overview. Biochem Soc Symp 1999;66:1-15.
25. Beeri R. Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int 1995;47:1806-1810.
26. Liberthal W, Menza SA, Levine JS. Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am J Physiol 1998;43:F315-F327.
27. Watson AJM. Necrosis and apoptosis in the gastrointestinal tract. Gut 1995;37:165-167.
28. Kim JM, Eckmann L, Savidge TC, et al. Apoptosis of the human intestinal epithelial cells after bacterial invasion. J Clin Invest 1998;102:1815-1823.
29. Daeman MA, van't Veer C, Denecker G, et al. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1999;104:541-549.
30. Kitamura H, Shimizu A, Masuda Y, et al. Apoptosis in glomerular endothelial cells during the development of glomeruloscleorosis in the remnant kidney model. Exp Nephrol 1998;6:328-336.
31. Papaconstantinou HT, Hwang KO, Rajaraman S, et al. Glutamine deprivation induces apoptosis in intestinal epithelial cells. Surgery 1998;124:152-160.
32. Mecklenburgh K, Murray J, Brazil T, et al. Role of neutrophil apoptosis in the resolution of pulmonary inflammation. Monaldi Arch Chest Dis 1999;54:345-349.
33. Fanning NF, Porter J, Shorten GD, et al. Inhibition of neutrophil apoptosis after elective surgery. Surgery 1999;126:527-534.
34. Noda T, Iwakiri R, Fujimoto K, et al. Programmed cell death induced by ischemia-reperfusion in rat intestinal mucosa. Am J Physiol 1998;274:G270-G276.
35. Johnson LR, McCormack SA. Regulation of gastrointestinal mucosal growth. In: Johnson LR, ed. Physiology of the gastrointestinal tract. 3rd ed. New York: Raven Press, 1994;611-641
36. Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994;15:1-4.
37. Ratan RR, Baraban JM. Apoptotic death in an in vitro model of neuronal oxidative stress. Clin Exp Pharmacol Physiol 1995;22:309-310.
38. Kang MY, Tsuchiya M, Packer L, et al. In vitro study on antioxidant potential of various drugs used in the perioperative period. Acta Anaesthesiol Scand 1998;42:4.
39. Ramachandran A, Balasubramanian KA. Protease activation during surgical stress in the rat small intestine. J Surg Res 2000; 92:283-290.
40. Anup R, Aparna V, Pulimood A, et al. Surgical stress and the small intestine: role of oxygen free radicals. Surgery 1999;125:560.
41. Rakestraw PC, Snyder JR, Woliner MJ, et al. involvement of nitric oxide in inhibitory neuromuscular transmission in equine jejunum. Am J Vet Res 1996;57:1206-1213.
42. Brunsson I. Enteric nerves mediate the fluid secretory response due to Salmonella typhimurium R5 infection in the rat small intestine. Acta Anaesthesiol Scand 1987;131:609-617.
43. Richter RA, Freeman DE, Wallig M, et al. Anion transport alterations and apoptosis induced by phenylbutazone in the equine right dorsal colon in vitro, in Proceedings, 7th Equine Colic Res Symp 2002;61.