Pharmacological evidence for involvement of phospholipase D, protein kinase C, and sodium-calcium exchanger in αadrenoceptor-mediated negative inotropy in adult mouse ventricle

Journal of Pharmacological Sciences

Volumn 92, Issue 3, 2003, Pages 196-202

  Nishimaru, Kazuhide ^a,b   Tanaka, Yoshio ^a   Tanaka, Hikaru ^a   Shigenobu, Koki ^a  

^a TOHO UNIVERSITY   (Japan)

^b YAMAGATA UNIVERSITY   (Japan)

Author keywords

Inotropy; Phospholipase D; Protein kinase C; Adrenoceptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1,6 HEXAMETHYLENEDICARBAMIC ACID BIS(CYCLOHEXANONE OXIME) ESTER; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; ALPHA ADRENERGIC RECEPTOR; CERAMIDE; INOTROPIC AGENT; LAVENDUSTIN A; LAVENDUSTIN B; LIPOPROTEIN LIPASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDATE PHOSPHATASE; PHOSPHOLIPASE C INHIBITOR; PHOSPHOLIPASE D; PHOSPHOLIPASE D INHIBITOR; PROPRANOLOL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; HEART VENTRICLE; INOTROPISM; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

EID: 0043066840     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.92.196     Document Type: Article

References (44)

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