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Similar values of the amount of energy evolved were obtained by integration of the peak area for all three compounds (155-162 KJ/mol). The large values suggest a radical process initiated by the cyclization process forming the biradical species. On scanning the thermolyzed samples a second time no exothermic features were registered which confirms that an irreversible process has taken place. The increased onset temperature for compound 3 might be explained by decreased product stability.
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25
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[14b] For the synthesis of other nitrogen-substituted enediynes, see: B. König, T. Fricke, I. Dix, P. G. Jones, J. Chem. Research (S) 1997, 68; J. Chem. Research (M) 1997, 385-394.
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