Synthesis of macrocyclic enediynes by twofold C-alkylation

Synthesis

Volumn , Issue 4, 1996, Pages 446-448

  König, Burkhard ^a   Pitsch, Wolfgang ^a   Dix, Ina ^a   Jones, Peter G ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MACROCYCLIC COMPOUND;

ALKYLATION; ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; THERMAL ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0029928040     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1996-4239     Document Type: Article

References (15)

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3. For a recent example, see: Anthony, J.; Boudon, C.; Diederich, F.; Gisselbrecht, J.-P.; Gramlich, V.; Gross, M.; Hobi, M.; Seiler, P. Angew. Chem. 1994, 106, 794; Angew. Chem., Int. Ed. Engl. 1994, 33, 763.
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10. Full details of the structure determination have been deposited at the Fachinformationszentrum Karlsruhe, D-76344 Eggenstein-Leopoldshafen, Germany, from where this material can be obtained on quoting the full literature citation and the reference number CSD-404 327 (6b) or CSD-404 843 (6c). (9) For the synthesis of the analogous methyl ester, see: Shoppee, C. W.; Hughes, N. W. J. Chem. Soc. C 1971, 3673.
11. No defined product could be isolated from the reaction with tetraethyl propane-1,1,3,3-tetracarboxylate. Guthzeit, M.; Drossel, O. Liebigs Ann. Chem. 1890, 256, 171.
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