메뉴 건너뛰기




Volumn 2, Issue 2, 2003, Pages 184-194

Microbial L-asparaginase: A potent antitumour enzyme

Author keywords

Acute lymphoblastic leukemia; Antilymphoma; Antitumour; Intracellular enzyme; L asparaginase

Indexed keywords

ANTINEOPLASTIC AGENT; ASPARAGINASE; BACTERIAL ENZYME; RECOMBINANT ENZYME;

EID: 0042977380     PISSN: 09725849     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (95)

References (91)
  • 1
    • 0018487381 scopus 로고
    • Treatment of L5178Y tumour bearing BDf mice with a non-immunogenic L-glutaminase-asparaginase
    • Abuchowski A et al, 1979. Treatment of L5178Y tumour bearing BDf mice with a non-immunogenic L-glutaminase-asparaginase. Cancer Treat Rep, 63, 1127-1129.
    • (1979) Cancer Treat Rep , vol.63 , pp. 1127-1129
    • Abuchowski, A.1
  • 2
    • 0017816524 scopus 로고
    • Effect of media composition on the growth and asparaginase production of Vibrio succinogenes
    • Albanase E & Kafkewitz D, 1978. Effect of media composition on the growth and asparaginase production of Vibrio succinogenes. Appl Environ Microbiol, 36, 25-30.
    • (1978) Appl Environ Microbiol , vol.36 , pp. 25-30
    • Albanase, E.1    Kafkewitz, D.2
  • 3
    • 0042255307 scopus 로고
    • A fungal L-asparaginase with potential antitumour activity
    • Ali S S et al, 1994. A fungal L-asparaginase with potential antitumour activity. Indian J Microbiol, 34, 73-76.
    • (1994) Indian J Microbiol , vol.34 , pp. 73-76
    • Ali, S.S.1
  • 4
    • 0024341467 scopus 로고
    • DNA methylation patterns associated with asparagine synthetase expression in asparagine overproducing and auxotrophic cells
    • Andrulis I L & Barrett M T. 1989. DNA methylation patterns associated with asparagine synthetase expression in asparagine overproducing and auxotrophic cells. Mol Cell Biol, 9, 2922-2930.
    • (1989) Mol Cell Biol , vol.9 , pp. 2922-2930
    • Andrulis, I.L.1    Barrett, M.T.2
  • 5
    • 0024374609 scopus 로고
    • In vitro and in vivo killing of ALL cells by L-asparaginase
    • Asselin B L et al, 1989. In vitro and in vivo killing of ALL cells by L-asparaginase. Cancer Res, 49, 4363-4369.
    • (1989) Cancer Res , vol.49 , pp. 4363-4369
    • Asselin, B.L.1
  • 6
    • 0042756520 scopus 로고    scopus 로고
    • Studies on production of L-asparaginase, an antitumour enzyme by a new bacterial isolate
    • Gulbarga University, Gulbarga. 9-11 November
    • Azmi W et al, 2001. Studies on production of L-asparaginase, an antitumour enzyme by a new bacterial isolate. 42 Conf Assoc Microbiol India, Gulbarga University, Gulbarga. 9-11 November.
    • (2001) 42 Conf Assoc Microbiol India
    • Azmi, W.1
  • 7
    • 0017096845 scopus 로고
    • Kinetics and properties of L-asparaginase and L-glutaminase activities of Pseudomonas ovalis
    • Badr E I et al. 1976. Kinetics and properties of L-asparaginase and L-glutaminase activities of Pseudomonas ovalis. Zentralbl Bakteriol parasetenkd Infektionskr Hyg, 131, 489-496.
    • (1976) Zentralbl Bakteriol parasetenkd Infektionskr Hyg , vol.131 , pp. 489-496
    • Badr, E.I.1
  • 8
    • 0034965123 scopus 로고    scopus 로고
    • Structural and functional stabilization of L-asparaginase via multisubunit immobilization onto highly activated supports
    • Balcao V M et al. 2001. Structural and functional stabilization of L-asparaginase via multisubunit immobilization onto highly activated supports. Biotechnol Prog, 17, 3, 537-542.
    • (2001) Biotechnol Prog , vol.17 , Issue.3 , pp. 537-542
    • Balcao M. V1
  • 9
    • 0016711967 scopus 로고
    • The properties and large scale production of L-asparaginase from Citrobacter
    • Bascomb S et al, 1975. The properties and large scale production of L-asparaginase from Citrobacter. J Gen Microbiol, 91, 1-16.
    • (1975) J Gen Microbiol , vol.91 , pp. 1-16
    • Bascomb, S.1
  • 10
    • 0006227301 scopus 로고
    • L-Asparaginase activity in bacteria from estuarine sediments and mollusks
    • Benny P J & Kurup G M, 1991. L-Asparaginase activity in bacteria from estuarine sediments and mollusks. Indian J Marine Sci, 20, 36-39.
    • (1991) Indian J Marine Sci , vol.20 , pp. 36-39
    • Benny, P.J.1    Kurup, G.M.2
  • 11
    • 0031090584 scopus 로고    scopus 로고
    • Asparaginase II of Saccharomyces cerevisiae. GLN3/URE2 regulation of a periplasmic enzyme
    • Bon E P et al, 1997. Asparaginase II of Saccharomyces cerevisiae. GLN3/URE2 regulation of a periplasmic enzyme. Appl Biochem Biotechnol, 63/65, 203-212.
    • (1997) Appl Biochem Biotechnol , vol.63-65 , pp. 203-212
    • Bon, E.P.1
  • 12
    • 36949081498 scopus 로고
    • Evidence that the L-asparaginase activity in guinea pig serum is responsible for its antilymphoma effects
    • Broome J D, 1961. Evidence that the L-asparaginase activity in guinea pig serum is responsible for its antilymphoma effects. Nature (Lond), 191, 1114-1115.
    • (1961) Nature (Lond) , vol.191 , pp. 1114-1115
    • Broome, J.D.1
  • 13
    • 75449125982 scopus 로고
    • Lymphoma 6C3HED cells cultured in a medium devoid of L-asparaginase loose their susceptibility to the effects of guinea pig serum in vivo
    • Broome J D, 1963. Lymphoma 6C3HED cells cultured in a medium devoid of L-asparaginase loose their susceptibility to the effects of guinea pig serum in vivo. J Exp Med, 118, 121-124.
    • (1963) J Exp Med , vol.118 , pp. 121-124
    • Broome, J.D.1
  • 14
    • 0014572988 scopus 로고
    • L-Asparaginase EC-2 from E.coli. Some substrate specificity characteristics
    • Campbell H A & Mashburn L T, 1969. L-Asparaginase EC-2 from E.coli. Some substrate specificity characteristics. Biochemistry, 8, 3766-3772.
    • (1969) Biochemistry , vol.8 , pp. 3766-3772
    • Campbell, H.A.1    Mashburn, L.T.2
  • 15
    • 0014064317 scopus 로고
    • Two Asparaginase front E. coli B, their separation, purification and antitumour property
    • Campbell H A et al, 1967. Two Asparaginase front E. coli B, their separation, purification and antitumour property. Biochemistry, 6, 721-730.
    • (1967) Biochemistry , vol.6 , pp. 721-730
    • Campbell, H.A.1
  • 16
    • 0027414441 scopus 로고
    • Asparaginase revisited
    • Capizzi R L, 1993. Asparaginase revisited. Leuk Lymphoma, 10, 147-159.
    • (1993) Leuk Lymphoma , vol.10 , pp. 147-159
    • Capizzi, R.L.1
  • 17
    • 0014934448 scopus 로고
    • L-Asparaginase induced immunosuppresion, effects on antibody forming cells and serum titres
    • Chakrabarti A K & Friedman H, 1970. L-Asparaginase induced immunosuppresion, effects on antibody forming cells and serum titres. Science, 167, 869-873.
    • (1970) Science , vol.167 , pp. 869-873
    • Chakrabarti, A.K.1    Friedman, H.2
  • 18
    • 0000917445 scopus 로고
    • L-Asparaginase desemidation enzymatique de L-asparagine chez les differentes especes animales et L-asparaginase signification physiologique de sa presence dans 1 organisma
    • Clementi A, 1922. L-Asparaginase desemidation enzymatique de L-asparagine chez les differentes especes animales et L-asparaginase signification physiologique de sa presence dans 1 organisma. Arch Int Physiol, 19, 369-376.
    • (1922) Arch Int Physiol , vol.19 , pp. 369-376
    • Clementi, A.1
  • 19
    • 0021827056 scopus 로고
    • A specific L-asparaginase from Thermus aquaticus
    • Curran M P et al, 1985. A specific L-asparaginase from Thermus aquaticus. Arch Biochem Biophys, 241, 571-576.
    • (1985) Arch Biochem Biophys , vol.241 , pp. 571-576
    • Curran, M.P.1
  • 20
    • 0001362058 scopus 로고
    • Reduction of immunogenicity and extension of circulating half life of peptides and proteins
    • edited by V H L Lee. Marcel Dekker, NewYork
    • Davis F F et al, 1991. Reduction of immunogenicity and extension of circulating half life of peptides and proteins, in Peptide and Protein Drug Delivery, edited by V H L Lee. Marcel Dekker, NewYork. Pp 831-851.
    • (1991) Peptide and Protein Drug Delivery , pp. 831-851
    • Davis, F.F.1
  • 21
    • 0024995640 scopus 로고
    • Intraperitoneal administration of carrier erythrocytes in dogs, an improved method for delivery of L-asperaginase
    • Deloach J R et al, 1990. Intraperitoneal administration of carrier erythrocytes in dogs, an improved method for delivery of L-asperaginase. Biotechnol App Biochem, 12, 331-339.
    • (1990) Biotechnol App Biochem , vol.12 , pp. 331-339
    • Deloach, J.R.1
  • 22
    • 0017085887 scopus 로고
    • Purification and characterization of L-asparaginase with antilymphoma activity from Vibrio succinogenes
    • Distasio J A et al, 1976. Purification and characterization of L-asparaginase with antilymphoma activity from Vibrio succinogenes. J Biol Chem, 251, 6929-6933.
    • (1976) J Biol Chem , vol.251 , pp. 6929-6933
    • Distasio, J.A.1
  • 23
    • 0022358686 scopus 로고
    • A conductimetric method for assaying asparaginase activity in Aspergillus nidu L-asparaginasens
    • Drainas D & Drainas C, 1985. A conductimetric method for assaying asparaginase activity in Aspergillus nidu L-asparaginasens. Eur J Biochem, 151, 591-593.
    • (1985) Eur J Biochem , vol.151 , pp. 591-593
    • Drainas, D.1    Drainas, C.2
  • 24
    • 0019302196 scopus 로고
    • Formation and properties of L-glutaminase and L-asparaginase activities in Pichia polymorpha
    • Foda M S et al, 1980. Formation and properties of L-glutaminase and L-asparaginase activities in Pichia polymorpha. Acta Microbil Pol, 29, 343-352.
    • (1980) Acta Microbil Pol , vol.29 , pp. 343-352
    • Foda, M.S.1
  • 25
    • 0024350661 scopus 로고
    • L-Asparaginase a drug for treatment of acute lymphoblastic leukemia
    • Gallagher M P et al, 1989. L-Asparaginase a drug for treatment of acute lymphoblastic leukemia. Essays Biochem, 24, 1-40.
    • (1989) Essays Biochem , vol.24 , pp. 1-40
    • Gallagher, M.P.1
  • 26
    • 0029683047 scopus 로고
    • Biological characterization of L-asparaginase liposomal formulations
    • Gasper M M et al, 1994. Biological characterization of L-asparaginase liposomal formulations. Cancer Chemother Pharmacol, 38, 373-378.
    • (1994) Cancer Chemother Pharmacol , vol.38 , pp. 373-378
    • Gasper, M.M.1
  • 27
    • 0042255303 scopus 로고
    • Method for the purification of Erwinia L-asperaginase. US Pat. 5310670; May 10, 1994
    • Goward C R, 1994. Method for the purification of Erwinia L-asperaginase. US Pat. 5310670; May 10, 1994.
    • (1994)
    • Goward, C.R.1
  • 28
    • 0024390179 scopus 로고
    • Organization and expression of the cell cycle gene ts II, encoding asparagine synthetase
    • Greco A et al, 1989. Organization and expression of the cell cycle gene ts II, encoding asparagine synthetase. Mol Cell Biol, 9, 2350-2361.
    • (1989) Mol Cell Biol , vol.9 , pp. 2350-2361
    • Greco, A.1
  • 29
    • 0043257664 scopus 로고
    • Stereospecific asparaginases. US Pat. 4473646; September 25, 1984
    • Guy et al, 1984. Stereospecific asparaginases. US Pat. 4473646; September 25, 1984.
    • (1984)
    • Guy1
  • 30
    • 0001372550 scopus 로고
    • The requirement for L-asparagine of mouse leukemia cells L5178Y in culture
    • Haley E E et al, 1961. The requirement for L-asparagine of mouse leukemia cells L5178Y in culture. Cancer Res, 21, 532-541.
    • (1961) Cancer Res , vol.21 , pp. 532-541
    • Haley, E.E.1
  • 31
    • 0015504954 scopus 로고
    • The in vivo blastogenesis inhibited by Erwinia caratovora L-asperaginase
    • Han T & Ohnuma T, 1972. The in vivo blastogenesis inhibited by Erwinia caratovora L-asperaginase. Nature (Lond), 239, 50-58.
    • (1972) Nature (Lond) , vol.239 , pp. 50-58
    • Han, T.1    Ohnuma, T.2
  • 32
    • 0022628485 scopus 로고
    • Cloning and expression of Erwinia crysanthemi asparaginase gene in E. coli and Erwinia carotovora
    • Harry J G et al, 1986. Cloning and expression of Erwinia crysanthemi asparaginase gene in E. coli and Erwinia carotovora. J Gen Microbiol, 132, 151-160.
    • (1986) J Gen Microbiol , vol.132 , pp. 151-160
    • Harry, J.G.1
  • 33
    • 0042756512 scopus 로고
    • Method for enzyme immobilization. US Pat. 4269941 May 26, 1981
    • Ichimura, 1981. Method for enzyme immobilization. US Pat. 4269941 May 26, 1981.
    • (1981)
    • Ichimura1
  • 34
    • 0017198775 scopus 로고
    • Purification and properties of L-asparaginase B from Acinatobacter calcoaceticus
    • Joner P E, 1976. Purification and properties of L-asparaginase B from Acinatobacter calcoaceticus. Biochem Biophys Acta, 438, 287-295.
    • (1976) Biochem Biophys Acta , vol.438 , pp. 287-295
    • Joner, P.E.1
  • 35
    • 0028283530 scopus 로고
    • Liposomal palmitoyl L-asperaginase; characterization and biological activity
    • Jorge J C et al, 1994. Liposomal palmitoyl L-asperaginase; characterization and biological activity. Cancer Chemother Pharmacol, 34, 230-241.
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 230-241
    • Jorge, J.C.1
  • 36
    • 0023766161 scopus 로고
    • Klinische erfahrungen mit polyathylengekoppelter E. coli Asparaginase bei patunten mit ALL-Mehrfachrezidiv klin
    • Jurgens H et al, 1988. Klinische erfahrungen mit polyathylengekoppelter E. coli Asparaginase bei patunten mit ALL-Mehrfachrezidiv klin. Padiatr, 200, 184-191.
    • (1988) Padiatr , vol.200 , pp. 184-191
    • Jurgens, H.1
  • 37
    • 0015963585 scopus 로고
    • L-Asparaginase production by the rumen anaerobe Vibrio succinogenes
    • Kafkewitz D & Goodman D, 1974. L-Asparaginase production by the rumen anaerobe Vibrio succinogenes. Appl Microbiol, 27, 206-209.
    • (1974) Appl Microbiol , vol.27 , pp. 206-209
    • Kafkewitz, D.1    Goodman, D.2
  • 38
    • 8544279767 scopus 로고
    • Regression of transplanted lymphomas induced in vivo by means of normal Guinea pig serum
    • Kidd J G, 1953. Regression of transplanted lymphomas induced in vivo by means of normal Guinea pig serum. J Exp Med, 98, 583-591.
    • (1953) J Exp Med , vol.98 , pp. 583-591
    • Kidd, J.G.1
  • 39
    • 85007863842 scopus 로고
    • Extraction of extracellular L-asparaginase from Candida utilis
    • Kil J O et al, 1995. Extraction of extracellular L-asparaginase from Candida utilis. Biosci Biotechnol Biochem, 59, 749-750.
    • (1995) Biosci Biotechnol Biochem , vol.59 , pp. 749-750
    • Kil, J.O.1
  • 40
    • 0017253880 scopus 로고
    • Hypersensitivity reactions and antibody formation during L-asparaginase treatment of children and adults with acute lymphoblastic leukemia
    • Killander D et al, 1976. Hypersensitivity reactions and antibody formation during L-asparaginase treatment of children and adults with acute lymphoblastic leukemia. Cancer, 37, 220-233.
    • (1976) Cancer , vol.37 , pp. 220-233
    • Killander, D.1
  • 41
    • 0026721637 scopus 로고
    • Chemical modification of L-asparaginase with a comb shaped copolymer of PEG and malic anhydride
    • Kodera Y et al, 1992. Chemical modification of L-asparaginase with a comb shaped copolymer of PEG and malic anhydride. Biochem Biophys Res Commun, 184, 144-154.
    • (1992) Biochem Biophys Res Commun , vol.184 , pp. 144-154
    • Kodera, Y.1
  • 42
    • 0025003462 scopus 로고
    • Erytheocytes as carriers for L-asparaginase. Methodological and mouse in vitro studies
    • Kravtzoff R et al, 1990, Erytheocytes as carriers for L-asparaginase. Methodological and mouse in vitro studies. J Pharm Pharmacol, 42, 473-479.
    • (1990) J Pharm Pharmacol , vol.42 , pp. 473-479
    • Kravtzoff, R.1
  • 44
    • 0029995124 scopus 로고    scopus 로고
    • Improved pharmacodynamics of L-asparaginase loaded in human red blood cells
    • Kravtzoff R et al, 1996. Improved pharmacodynamics of L-asparaginase loaded in human red blood cells. Eur J Clin Pharmacol, 49, 465.
    • (1996) Eur J Clin Pharmacol , vol.49 , pp. 465
    • Kravtzoff, R.1
  • 45
    • 0042255301 scopus 로고
    • Large scale recovery and purification of an antileukemia drug, L-asparaginase from Erwinia carotovora
    • 190 Meet
    • Lee S M et al, 1985. Large scale recovery and purification of an antileukemia drug, L-asparaginase from Erwinia carotovora. Abstr Pap Am Chem Soc, 190 Meet.
    • (1985) Abstr Pap Am Chem Soc
    • Lee, S.M.1
  • 46
    • 0042255294 scopus 로고
    • Process for manufacture of L-asparaginase from Erwinia chrysanthemi. US Pat. 4729957; March 8, 1988
    • Lee S M et al, 1988. Process for manufacture of L-asparaginase from Erwinia chrysanthemi. US Pat. 4729957; March 8, 1988.
    • (1988)
    • Lee, S.M.1
  • 47
    • 0027816225 scopus 로고
    • Fermentative production and isolation of L-asparaginase from Erwinia carotovora, EC-113
    • Maladkar N K et al. 1993. Fermentative production and isolation of L-asparaginase from Erwinia carotovora, EC-113. Hindustan Antibiotic Bull, 35, 77-86.
    • (1993) Hindustan Antibiotic Bull , vol.35 , pp. 77-86
    • Maladkar, N.K.1
  • 48
    • 0028908086 scopus 로고
    • Purification, characterization and antitumour activity of L-asparaginase isolated from Pseudomonas stutzeri MB-405
    • Manna S et al, 1995. Purification, characterization and antitumour activity of L-asparaginase isolated from Pseudomonas stutzeri MB-405. Curr Microbiol, 30, 291-198.
    • (1995) Curr Microbiol , vol.30 , pp. 291-198
    • Manna, S.1
  • 49
    • 0002414574 scopus 로고
    • Molecular genetics of amino acid producing Corynebacteria
    • Martin J F, 1989. Molecular genetics of amino acid producing Corynebacteria. Symp soc Gen Microbiol, 44, 25-59.
    • (1989) Symp Soc Gen Microbiol , vol.44 , pp. 25-59
    • Martin, J.F.1
  • 50
    • 0025162710 scopus 로고
    • Acylation of L-asparaginase with total retention of enzymatic activity
    • Martins M B et al, 1990. Acylation of L-asparaginase with total retention of enzymatic activity. Biochemie, 72, 671-680.
    • (1990) Biochemie , vol.72 , pp. 671-680
    • Martins, M.B.1
  • 51
    • 0042255293 scopus 로고
    • Process for producing immobilized L-asparaginase preparations for the therapy of leukemia. US Pat, 4, 617, 271; October 14, 1986
    • Masao N, 1986. Process for producing immobilized L-asparaginase preparations for the therapy of leukemia. US Pat, 4, 617, 271; October 14, 1986.
    • (1986)
    • Masao, N.1
  • 52
    • 50549191387 scopus 로고
    • Tumour inhibitory effect of L-asparaginase from E. coli
    • Mashburn L T & Wriston J C, 1964. Tumour inhibitory effect of L-asparaginase from E.coli. Arch Biochem, 105, 450-458.
    • (1964) Arch Biochem , vol.105 , pp. 450-458
    • Mashburn, L.T.1    Wriston, J.C.2
  • 53
    • 0023225826 scopus 로고
    • A preliminary study on the evaluation of asparaginase
    • McEwen E G et al, 1987. A preliminary study on the evaluation of asparaginase. Cancer, 59, 2011-2020.
    • (1987) Cancer , vol.59 , pp. 2011-2020
    • McEwen, E.G.1
  • 54
    • 0025332327 scopus 로고
    • Characterization and partial purification of L-asparaginase from Corynebacterium glutamicum
    • Mesas J M et al, 1990. Characterization and partial purification of L-asparaginase from Corynebacterium glutamicum. J Gen Microbiol, 136, 515-519.
    • (1990) J Gen Microbiol , vol.136 , pp. 515-519
    • Mesas, J.M.1
  • 55
    • 0017364198 scopus 로고    scopus 로고
    • Factors influencing L-asparaginase production by Staphylococci
    • Mikucki J et al, 1997. Factors influencing L-asparaginase production by Staphylococci. Zentralbl Bakteriol Parasetenkd Infektionskr Hyg, 132, 135-142.
    • (1997) Zentralbl Bakteriol Parasetenkd Infektionskr Hyg , vol.132 , pp. 135-142
    • Mikucki, J.1
  • 56
    • 0028973207 scopus 로고
    • Characterization of L-asparaginase from Bacillus sp isolated from an intertidal marine alga (Sargassum sp)
    • Mohapatra B R et al, 1995. Characterization of L-asparaginase from Bacillus sp isolated from an intertidal marine alga (Sargassum sp). Lett Appl Microbiol, 21, 380-383.
    • (1995) Lett Appl Microbiol , vol.21 , pp. 380-383
    • Mohapatra, B.R.1
  • 57
    • 0031306180 scopus 로고    scopus 로고
    • Production and properties of L-asparaginase from Mucor sp associated with a marine sponge (Spirastrella sp.)
    • Mohapatra B R et al, 1997. Production and properties of L-asparaginase from Mucor sp associated with a marine sponge (Spirastrella sp.). Cytobios, 92, 165-173.
    • (1997) Cytobios , vol.92 , pp. 165-173
    • Mohapatra, B.R.1
  • 58
    • 0028136892 scopus 로고
    • Erwinia chrysanthemi L-asparaginase; epitope mapping and production of antigenically modified enzymes
    • Moola Z B et al, 1994. Erwinia chrysanthemi L-asparaginase; epitope mapping and production of antigenically modified enzymes. Biochem J, 302, 921-927.
    • (1994) Biochem J , vol.302 , pp. 921-927
    • Moola, Z.B.1
  • 59
    • 0018554469 scopus 로고
    • Activity of L-asparaginase in cells of Streptomyces karnatakensis
    • Mostafa S A, 1979a. Activity of L-asparaginase in cells of Streptomyces karnatakensis. Zentralbl Bacteriol (Naturwiss), 134, 343-351.
    • (1979) Zentralbl Bacteriol (Naturwiss) , vol.134 , pp. 343-351
    • Mostafa, S.A.1
  • 60
    • 0018353273 scopus 로고
    • Production of L-asparaginase by Streptomyces karnatakensis and Streptomyces venezuelae
    • Mostafa S A, 1979b. Production of L-asparaginase by Streptomyces karnatakensis and Streptomyces venezuelae. Zentralbl Bakteriol (orig A), 134, 429-436.
    • (1979) Zentralbl Bakteriol (Orig A) , vol.134 , pp. 429-436
    • Mostafa, S.A.1
  • 61
    • 0021001429 scopus 로고
    • L-Asparaginase activity in cell free extracts of Thermoactinomyces vulgaris 13 M.E.S
    • Mostafa S A & Ali O A, 1983. L-Asparaginase activity in cell free extracts of Thermoactinomyces vulgaris 13 M.E.S. Zbl Microbiol, 5, 397-404.
    • (1983) Zbl Microbiol , vol.5 , pp. 397-404
    • Mostafa, S.A.1    Ali, O.A.2
  • 62
    • 0018591485 scopus 로고
    • L-asparagine producing Streptomyces from soil of Kuwait
    • Mostafa S A & Salama M S, 1979. L-asparagine producing Streptomyces from soil of Kuwait. Zentralbl Bakteriol (Naturwiss), 134, 325-334.
    • (1979) Zentralbl Bakteriol (Naturwiss) , vol.134 , pp. 325-334
    • Mostafa, S.A.1    Salama, M.S.2
  • 63
    • 0020020675 scopus 로고
    • Properties of L-asparaginase in cell free extract of Streptomyces karnatakensis
    • Mostafa S A, 1982. Properties of L-asparaginase in cell free extract of Streptomyces karnatakensis. Zentralbl Mikrobiol, 137, 63-71.
    • (1982) Zentralbl Mikrobiol , vol.137 , pp. 63-71
    • Mostafa, S.A.1
  • 64
    • 0034005352 scopus 로고    scopus 로고
    • Studies on nutritional and oxygen requirements for production of L-asparaginase by Enterobacter aerogenes
    • Mukherjee J et al, 2000. Studies on nutritional and oxygen requirements for production of L-asparaginase by Enterobacter aerogenes. Appl Microbiol Biotechnol, 53, 180-184.
    • (2000) Appl Microbiol Biotechnol , vol.53 , pp. 180-184
    • Mukherjee, J.1
  • 65
    • 0023710468 scopus 로고    scopus 로고
    • Determination of parameters for enzyme therapy using L-asparaginase entrapped in canine erythrocytes
    • Nagi A et al, 1998. Determination of parameters for enzyme therapy using L-asparaginase entrapped in canine erythrocytes. Biotechnol Appl Biochem, 10, 365-373.
    • (1998) Biotechnol Appl Biochem , vol.10 , pp. 365-373
    • Nagi, A.1
  • 66
    • 0031730828 scopus 로고    scopus 로고
    • Isolation and characterization of Enterobacter cloacae capable of metabolizing L-asparagine
    • Nawaz M S et al, 1998. Isolation and characterization of Enterobacter cloacae capable of metabolizing L-asparagine. Appl Microbiol Biochem, 50, 568-572.
    • (1998) Appl Microbiol Biochem , vol.50 , pp. 568-572
    • Nawaz, M.S.1
  • 67
    • 0017902138 scopus 로고
    • Biosynthesis of L-asparaginase II by cultures of Bacillus polymyxa var. Ross
    • Nefelova M V et al, 1978. Biosynthesis of L-asparaginase II by cultures of Bacillus polymyxa var. Ross. Prikl Biokhim Mikrobiol, 14, 510-514.
    • (1978) Prikl Biokhim Mikrobiol , vol.14 , pp. 510-514
    • Nefelova, M.V.1
  • 68
    • 0024793497 scopus 로고
    • Modification of L-asparaginase from Erwinia caratovora using human serum albumin
    • Nerkar D P & Gangadharan. 1989. Modification of L-asparaginase from Erwinia caratovora using human serum albumin. Mol Biother, 1, 152.
    • (1989) Mol Biother , vol.1 , pp. 152
    • Nerkar, D.P.1    Gangadharan2
  • 69
    • 0017354990 scopus 로고
    • Stimulation of L-asparaginase production in E. coli by organic and amino acids
    • Netrval J, 1977. Stimulation of L-asparaginase production in E. coli by organic and amino acids. Folia Microbiol (Praha), 22, 106-116.
    • (1977) Folia Microbiol (Praha) , vol.22 , pp. 106-116
    • Netrval, J.1
  • 70
    • 0010438308 scopus 로고
    • Dual requirement of Walker carcinosarcoma 256 in vitro for L-asparagine and Glutamine
    • Neuman R E & McCoy T A, 1956. Dual requirement of Walker carcinosarcoma 256 in vitro for L-asparagine and Glutamine. Science, 124, 124-131.
    • (1956) Science , vol.124 , pp. 124-131
    • Neuman, R.E.1    McCoy, T.A.2
  • 71
    • 0014169820 scopus 로고
    • Inhibition of leukemias in man by L-asperaginase
    • Oettgen H F et al, 1967. Inhibition of leukemias in man by L-asperaginase. Cancer Res, 27, 2619-2631.
    • (1967) Cancer Res , vol.27 , pp. 2619-2631
    • Oettgen, H.F.1
  • 72
    • 0017183936 scopus 로고
    • Purification and properties of L-asparaginase from Mycobacterium phlei
    • Pastuszak I & Szymona M, 1976. Purification and properties of L-asparaginase from Mycobacterium phlei. Acta Biochem Pol, 23, 37-44.
    • (1976) Acta Biochem Pol , vol.23 , pp. 37-44
    • Pastuszak, I.1    Szymona, M.2
  • 73
    • 0019956539 scopus 로고
    • Isolation and characterization of a Chlamydomonas L-asparaginase
    • Paul J H, 1982. Isolation and characterization of a Chlamydomonas L-asparaginase. Biochemical J, 203, 109-115.
    • (1982) Biochemical J , vol.203 , pp. 109-115
    • Paul, J.H.1
  • 74
    • 0035125429 scopus 로고    scopus 로고
    • L-asparaginase of Thermus thermophilus: Purification, properties and identification of essential amino acids for its catalytic activity
    • Pritsa A A & Kyriakidis D A, 2001. L-asparaginase of Thermus thermophilus: Purification, properties and identification of essential amino acids for its catalytic activity. Mol Cell Biochem, 216, 93-101.
    • (2001) Mol Cell Biochem , vol.216 , pp. 93-101
    • Pritsa, A.A.1    Kyriakidis, D.A.2
  • 75
    • 0025088396 scopus 로고
    • Purification and properties of L-asparaginase from Cylindrocarpon obtusisporum MB-10
    • Raha S K et al, 1990. Purification and properties of L-asparaginase from Cylindrocarpon obtusisporum MB-10. J Biochem Int, 21, 987-1000.
    • (1990) J Biochem Int , vol.21 , pp. 987-1000
    • Raha, S.K.1
  • 76
    • 0042255295 scopus 로고
    • Effect of carbon and nitrogen sources on L-asparaginase production by bacteria
    • Reddy V K & Reddy S M, 1990. Effect of carbon and nitrogen sources on L-asparaginase production by bacteria. Indian J Microbiol, 30, 81-83.
    • (1990) Indian J Microbiol , vol.30 , pp. 81-83
    • Reddy K. V1    Reddy, S.M.2
  • 77
    • 0015499931 scopus 로고
    • Isolation, characterization and properties of Achromobacteriaceae glutaminase-asparaginase with antitumour activity
    • Roberts J et al, 1972. Isolation, characterization and properties of Achromobacteriaceae glutaminase-asparaginase with antitumour activity. J Biol Chem, 247, 84-90.
    • (1972) J Biol Chem , vol.247 , pp. 84-90
    • Roberts, J.1
  • 79
    • 0027024967 scopus 로고
    • Staphylococcal L-asperaginase; catabolic repression of synthesis
    • Rozalska M & Mikucki J, 1992. Staphylococcal L-asperaginase; catabolic repression of synthesis. Acta Microbiol Pol, 41, 145-150.
    • (1992) Acta Microbiol Pol , vol.41 , pp. 145-150
    • Rozalska, M.1    Mikucki, J.2
  • 80
    • 0004160155 scopus 로고
    • edited by J S Holcenberg & J Roberts. Wiley Inter Science, New York
    • Schemer G & Holcenberg J S, 1981. Enzymes as drugs, edited by J S Holcenberg & J Roberts. Wiley Inter Science, New York. Pp 455-473.
    • (1981) Enzymes as Drugs , pp. 455-473
    • Schemer, G.1    Holcenberg, J.S.2
  • 81
    • 0030928060 scopus 로고    scopus 로고
    • Amino acid utilization and deamination of glutamine and asparagine by Helicobacter pylori
    • Stark R M et al, 1997. Amino acid utilization and deamination of glutamine and asparagine by Helicobacter pylori. J Med Microbiol, 46, 793-800.
    • (1997) J Med Microbiol , vol.46 , pp. 793-800
    • Stark, R.M.1
  • 82
    • 0006243841 scopus 로고
    • Some questions of thermostability of L-asparaginase of yeast Candida guilliermondii
    • Stepanyan K R & Davtyan M A, 1988. Some questions of thermostability of L-asparaginase of yeast Candida guilliermondii. Biologicheskii Zhurnal Armenii, 41, 599-603.
    • (1988) Biologicheskii Zhurnal Armenii , vol.41 , pp. 599-603
    • Stepanyan, K.R.1    Davtyan, M.A.2
  • 83
    • 0015341951 scopus 로고
    • Activity and properties of L-asparaginase from Bacillus mesentericus
    • 43A
    • Tiul' Panova E S et al, 1972. Activity and properties of L-asparaginase from Bacillus mesentericus. 43A. Microbiologika, 41, 423-429.
    • (1972) Microbiologika , vol.41 , pp. 423-429
    • Tiul' Panova, E.S.1
  • 84
    • 0030256423 scopus 로고    scopus 로고
    • Purification and preliminary characterization of L-asparaginase from Erwinia aroideae
    • Tiwari N & Dua R D, 1996. Purification and preliminary characterization of L-asparaginase from Erwinia aroideae. Indian J Biochem Biophys, 33, 371-376.
    • (1996) Indian J Biochem Biophys , vol.33 , pp. 371-376
    • Tiwari, N.1    Dua, R.D.2
  • 85
    • 0025316637 scopus 로고
    • L-Asparaginase of Tetrahymena pyriformis is associated with a kinase activity
    • Tsirka S A & Kiriakidis D A 1990. L-Asparaginase of Tetrahymena pyriformis is associated with a kinase activity. Mol Cell Biochem, 95, 77-78.
    • (1990) Mol Cell Biochem , vol.95 , pp. 77-78
    • Tsirka, S.A.1    Kiriakidis, D.A.2
  • 86
    • 0018757159 scopus 로고
    • Improvement of therapeutic immunological and clearance properties of E. coli and Erwinia caratovora L-asparaginases by attachment of poly-DL-alanyl peptides
    • Uren J R & Ragin R C, 1979. Improvement of therapeutic immunological and clearance properties of E. coli and Erwinia caratovora L-asparaginases by attachment of poly-DL-alanyl peptides. Cancer Res, 39, 1927-1933.
    • (1979) Cancer Res , vol.39 , pp. 1927-1933
    • Uren, J.R.1    Ragin, R.C.2
  • 87
    • 0041754640 scopus 로고    scopus 로고
    • L-Asperaginase: An essential antineoplastic drug
    • edited by A Lauwers & S Scharpe. Marcel Dekker Inc, New York
    • Wahn V, 1997. L-Asperaginase: An essential antineoplastic drug, in Pharmaceutical Enzyme, edited by A Lauwers & S Scharpe. Marcel Dekker Inc, New York. Pp 223-260.
    • (1997) Pharmaceutical Enzyme , pp. 223-260
    • Wahn, V.1
  • 88
    • 0022618049 scopus 로고
    • The ecology of antibiotics production
    • Williams S T & Vikers J C, 1986. The ecology of antibiotics production. Microbial Ecology, 12, 43-52.
    • (1986) Microbial Ecology , vol.12 , pp. 43-52
    • Williams, S.T.1    Vikers, J.C.2
  • 89
    • 0022908309 scopus 로고
    • Characterization of PEG modified L-asparaginase from E. coli and its application to the therapy of leukemia
    • Yashimoto T et al, 1986. Characterization of PEG modified L-asparaginase from E. coli and its application to the therapy of leukemia. Jpn J Cancer Res, 77, 1264-1271.
    • (1986) Jpn J Cancer Res , vol.77 , pp. 1264-1271
    • Yashimoto, T.1
  • 90
    • 0014027153 scopus 로고
    • Antagonism of purified asparaginase from guinea pig serum towards lymphoma
    • Yellin T Y & Wriston J C, 1966. Antagonism of purified asparaginase from guinea pig serum towards lymphoma. Science, 151, 998-1004.
    • (1966) Science , vol.151 , pp. 998-1004
    • Yellin, T.Y.1    Wriston, J.C.2
  • 91
    • 0034965287 scopus 로고    scopus 로고
    • 4 and Triton X-100
    • 4 and Triton X-100. Biotechnol Progr. 17, 3, 490-494.
    • (2001) Biotechnol Progr , vol.17 , Issue.3 , pp. 490-494
    • Zaho, F.1    Yu, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.