Perfusion thresholds in acute stroke thrombolysis

Stroke

Volumn 34, Issue 9, 2003, Pages 2159-2164

  Butcher, K ^a,c   Parsons, M ^a   Baird, T ^a   Barber, A ^a   Donnan, G ^b   Desmond, P ^d   Tress, B ^a   Davis, S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b AUSTIN HEALTH   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

^d NONE

Author keywords

Magnetic resonance imaging; Perfusion; Thrombolysis

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AGED; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN PERFUSION; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; PRIORITY JOURNAL; STROKE;

ACUTE DISEASE; AGED; BLOOD FLOW VELOCITY; BLOOD VOLUME; BRAIN MAPPING; CEREBRAL INFARCTION; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR CIRCULATION; ECHO-PLANAR IMAGING; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; THROMBOLYTIC THERAPY; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0042919443     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000086529.83878.A2     Document Type: Article

References (34)

1. Kwiatkowski TG, Libman RB, Frankel M, Tilley BC, Morgenstern LB, Lu M, Broderick JP, Lewandowski CA, Marler JR, Levine SR, Brott T, for the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study Group. Effects of tissue plasminogen activator for acute ischemic stroke at one year. N Engl J Med. 1999;340:1781-1787.
2. Hacke W. Advances in stroke management: update 1998. Neurology. 1999;53(suppl 4):S1-S2.
3. Ringleb PA, Schellinger PD, Schranz C, Hacke W. Thrombolytic therapy within 3 to 6 hours after onset of ischemic stroke: useful of or harmful? Stroke. 2002;33:1437-1441.
4. Albers GW. Expanding the window for thrombolytic therapy in acute stroke: the potential role of acute MRI for patient selection. Stroke. 1999;30:2230-2237.
5. Baird AE, Warach S. Magnetic resonance imaging of acute stroke. J Cereb Blood Flow Metab. 1998;18:583-609.
6. Ostergaard L, Weisskoff RM, Chesler DA, Gyldensted C, Rosen BR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages, part I: mathematical approach and statistical analysis. Magn Reson Med. 1996;36:715-725.
7. Davis S, Tress B, Barber PA, Darby D, Parsons M, Gerraty R, Yang Q, Donnan G, Desmond P. Echoplanar magnetic resonance imaging in acute stroke. J Clin Neurosci. 2000;7:3-8.
8. Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemia: the ischemic penumbra. Stroke. 1981;12:723-725.
9. Karonen JO, Vanninen RL, Liu Y, Ostergaard L, Kuikka JT, Nuutinen J, Vanninen EJ, Partanen PL, Vainio PA, Korhonen K, et al. Combined diffusion and perfusion MRI with correlation to single-photon emission CT in acute ischemic stroke: ischemic penumbra predicts infarct growth. Stroke. 1999;30:1583-1590.
10. Schlaug G, Benfield A, Baird AE, Siewert B, Lovblad KO, Parker RA, Edelman RR, Warach S. The ischemic penumbra: operationally defined by diffusion and perfusion MRI. Neurology. 1999;53:1528-1537.
11. Barber PA, Darby DG, Desmond PM, Yang Q, Gerraty RP, Jolley D, Donnan GA, Tress BM, Davis SM. Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted magnetic resonance imaging. Neurology. 1998;51:418-426.
12. Parsons MW, Yang Q, Barber PA, Darby DG, Desmond PM, Gerraty RP, Tress BM, Davis SM. Perfusion magnetic resonance imaging maps in hyperacute stroke: relative cerebral blood flow most accurately identifies tissue destined to infarct. Stroke. 2001;32:1581-1587.
13. Thijs VN, Adami A, Neumann-Haefelin T, Moseley ME, Marks MP, Albers GW. Relationship between severity of MR perfusion deficit and DWI lesion evolution. Neurology. 2001;57:1205-1211.
14. Neumann-Haefelin T, Wittsack HJ, Wenserski F, Siebler M, Seitz RJ, Modder U, Freund HJ. Diffusion- and perfusion-weighted MRI: the DWI/PWI mismatch region in acute stroke. Stroke. 1999;30:1591-1597.
15. Desmond PM, Lovell AC, Rawlinson AA, Parsons MW, Barber PA, Yang Q, Li T, Darby DG, Gerraty RP, Davis SM, Tress BM. The value of apparent diffusion coefficient maps in early cerebral ischemia. AJNR Am J Neuroradiol. 2001;22:1260-1267.
16. Fiehler J, Foth M, Kucinski T, Knab R, von Bezold M, Weiller C, Zeumer H, Rother J. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke. 2002;33:79-86.
17. Rohl L, Ostergaard L, Simonsen CZ, Vestergaard-Poulsen P, Andersen G, Sakoh M, Le Bihan D, Gyldensted C. Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient. Stroke. 2001;32:1140-1146.
18. Sorensen AG, Copen WA, Ostergaard L, Buonanno FS, Gonzalez RG, Rordorf G, Rosen BR, Schwamm LH, Weisskoff RM, Koroshetz WJ. Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time. Radiology. 1999;210:519-527.
19. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
20. Hacke W, Kaste M, Fieschi C. Randomised double-blind placebo controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet. 1998;352:1245-1251.
21. Ostergaard L, Sorensen AG, Kwong KK, Weisskoff RM, Gyldensted C, Rosen BR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages, part II: experimental comparison and preliminary results. Magn Reson Med. 1996;36:726-736.
22. Powers WJ, Grubb RL, Jr., Darriet D, Raichle ME. Cerebral blood flow and cerebral metabolic rate of oxygen requirements for cerebral function and viability in humans. J Cereb Blood Flow Metab. 1985;5:600-608.
23. Heiss WD. Flow thresholds for functional and morphological damage of brain tissue. Stroke. 1983;14:329-331.
24. Hossmann KA. Viability thresholds and the penumbra of focal ischemia. Ann Neurol. 1994;36:557-565.
25. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin YP, Jahan R, Vespa P, Kalafut M, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Ann Neurol. 2000;47:462-469.
26. Parsons MW, Barber PA, Chalk J, Darby DG, Rose S, Desmond PM, Gerraty RP, Tress BM, Wright PM, Donnan GA, Davis SM. Diffusion- and perfusion-weighted MRI response to thrombolysis in stroke. Ann Neurol. 2002;51:28-37.
27. Marler JR, Tilley BC, Lu M, Brott TG, Lyden PC, Grotta JC, Broderick JP, Levine SR, Frankel MP, Horowitz SH, et al. Early stroke treatment associated with better outcome: the NINDS rt-PA Stroke Study. Neurology. 2000;55:1649-1655.
28. Kaste M, for the ATLANTIS, ECASS and NINDS Study Group Investigators. Is there benefit after 3 hours? A pooled analysis of the ATLANTIS, ECASS and NINDS rtPA stroke trials. In: Program and abstracts of the Seventh Annual Conference on Thrombolysis and Acute Stroke Therapy; May 27-29, 2002; Lyon, France. Abstract.
29. Yamada K, Wu O, Gonzalez RG, Bakker D, Ostergaard L, Copen WA, Weisskoff RM, Rosen BR, Yagi K, Nishimura T, Sorensen AG. Magnetic resonance perfusion-weighted imaging of acute cerebral infarction: effect of the calculation methods and underlying vasculopathy. Stroke. 2002; 33:87-94.
30. Weisskoff RM, Chesler D, Boxerman JL, Rosen BR. Pitfalls in MR measurement of tissue blood flow with intravascular tracers: which mean transit time? Magn Reson Med. 1993;29:553-559.
31. Lin W, Celik A, Derdeyn C, An H, Lee Y, Videen T, Ostergaard L, Powers WJ. Quantitative measurements of cerebral blood flow in patients with unilateral carotid artery occlusion: a PET and MR study. J Magn Reson Imaging. 2001;14:659-667.
32. Rempp KA, Brix G, Wenz F, Becker CR, Guckel F, Lorenz WJ. Quantification of regional cerebral blood flow and volume with dynamic susceptibility contrast-enhanced MR imaging. Radiology. 1994;193: 637-641.
33. Neumann-Haefelin T, Moseley ME, Albers GW. New magnetic resonance imaging methods for cerebrovascular disease: emerging clinical applications. Ann Neurol. 2000;47:559-570.
34. Calamante F, Gadian DG, Connelly A. Quantification of perfusion using bolus tracking magnetic resonance imaging in stroke: assumptions, limitations, and potential implications for clinical use. Stroke. 2002;33: 1146-1151.