Expanding the window for thrombolytic therapy in acute stroke: The potential role of acute MRI for patient selection

Stroke

Volumn 30, Issue 10, 1999, Pages 2230-2237

  Albers, Gregory W ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Magnetic resonance imaging, diffusion weighted; Magnetic resonance imaging, perfusion weighted; Stroke, acute; Thrombolysis

Indexed keywords

FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR;

BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN PERFUSION; BRAIN REGION; FIBRINOLYTIC THERAPY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAGNETIC RESONANCE ANGIOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SELECTION; PRIORITY JOURNAL; REVIEW; SCREENING; STROKE;

EID: 0032822615     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.30.10.2230     Document Type: Review

References (62)

1. Jansen O, Schellinger P, Fiebach J, Hacke W, Sartor K. Early recanalisation in acute ischaemic stroke saves tissue at risk defined by MRI. Lancet. 1999;353:2036-2037.
2. Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, Gobin P, Vespa P, Kalafut M, Jahan R, Alger JR. Thrombolytic reversal of acute human cerebral ischemic injury demonstrated by diffusion/perfusion magnetic resonance imaging. Neurology. 1999; 52(suppl 2):A536. Abstract.
3. The National Institute of Neurological Disorders, and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
4. Fagan SC, Morgenstern LB, Petitta A, Ward RE, Tilley BC, Marler JR, Levine SR, Broderick JP, Kwiatkowski TG, Frankel M, Brott TG, Walker MD for the NINDS rt-PA Stroke Study Group. Costeffectiveness of tissue plasminogen activator for acute ischemic stroke. Neurology. 1998;50:883-890.
5. Practice advisory: thrombolytic therapy for acute ischemic stroke: summary statement: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 1996;47:835-839.
6. Adams HP Jr, Brott TG, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Kwiatkowski T, Lyden PD, Marler JR, Torner J, Feinberg W, Mayberg M, Thies W. Guidelines for Thrombolytie Therapy for Acute Stroke: a supplement to the guidelines for the management of patients with acute ischemic stroke: a statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association. Stroke. 1996;27:1711-1718.
7. Albers GW, Easton JD, Sacco RL, Teal P. Antithrombotic and thrombolytic therapy for ischemic stroke. Chest. 1998;114(suppl 5):683S-698S.
8. Zweifler RM, Brody ML, Graves GC, U TT, Drinkard R, Cunningham S, Rothrock JF. Intravenous t-PA for acute ischemic stroke: therapeutic yield of a stroke code system. Neurology. 1998;50:501-503.
9. Hacke W, Kaste M, Fieschi C, Toni D, Lesaffre E, von Kummer R, Boysen G, Bluhmki E, Hoxter G, Mahagne MH, Hennerici M for the ECASS Study Group. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. JAMA. 1995;274:1017-1025.
10. von Kummer R, Allen KL, Holle R, Bozzao L, Bastianello S, Manelfe C, Bluhmki E, Ringleb P, Meier DH, Hacke W. Acute stroke: usefulness of early CT findings before thrombolytic therapy. Radiology. 1997;205:327-333.
11. Hacke W, Kaste M, Fieschi C, von Kummer R, Davalos A, Meier D, Larrue V, Bluhmki E, Davis S, Donnan G, Schneider D, Diez-Tejedor E, Trouillas P. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet. 1998;352:1245-1251.
12. Clark WM, Albers GW for the ATLANTIS Stroke Study Investigators. The ATLANTIS rt-PA acute stroke trial: final results. Stroke. 1999;30:234. Abstract.
13. Furlan AJ, Higashida R, Wechsler L, Schultz G for the PROACT II Investigators. PROACT II: recombinant prourokinase (r-ProUK) in acute cerebral thromboembolism. initial trial results. Stroke. 1999; 30:234. Abstract.
14. Fisher M, Prichard JW, Warach S. New magnetic resonance techniques for acute ischemic stroke. JAMA. 1995;274:908-911.
15. Fisher M, Albers GW. Applications of diffusion-perfusion magnetic resonance imaging in acute ischemic stroke. Neurology. 1999;52: 1750-1756.
16. Li F, Han S, Tatlisumak T, Carano RA, Irie K, Sotak CH, Fisher M. A new method to improve in-bore middle cerebral artery occlusion in rats: demonstration with diffusion-and perfusion-weighted imaging. Stroke. 1998;29:1715-1719.
17. Moseley ME, Cohen Y, Mintorovitch J, Chileuitt L, Shimizu H, Kucharczyk J, Wendland MF, Weinstein PR. Early detection of regional cerebral ischemia in cats: comparison of diffusion-and T2-weighted MRI and spectroscopy. Magn Reson Med. 1990;14: 330-346.
18. Moseley ME, Kucharczyk J, Mintorovitch J, Cohen Y, Kurhanewicz J, Derugin N, Asgari H, Norman D. Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am J Neururadiol. 1990;11:423-429.
19. Verheul HB, Balazs R, Berkelbach van der Sprenkel JW, Tulleken CA, Nicolay K, Tamminga KS, van Lockeren Campagne M. Comparison of diffusion-weighted MRI with changes in cell volume in a rat model of brain injury. NMR Biomed. 1994;7:96-100.
20. van Bruggen N, Roberts TP, and Cremer JE. The application of magnetic resonance imaging to the study of experimental cerebral ischaemia. Cerebrovasc Brain Metab Rev. 1994;6:180-210.
21. van Lookeren Campagne M, Verheul HB, Vermeulen JP, Balázs R, Boer GJ, Nicolay K. Developmental changes in NMDA-induced cell swelling and its transition to necrosis measured with 1H magnetic resonance imaging, impedance and histology. Brain Res Dev Brain Res. 1996;93:109-119.
22. Hoehn-Berlage M, Norris DG, Kohno K, Mies G, Leibfritz D, Hossmann KA. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances. J Cereb Blood Flow Metab. 1995; 15:1002-1011.
23. Benveniste H, Hedlund, LW, Johnson, GA. Mechanism of detection of acute cerebral ischemia in rats by diffusion-weighted magnetic resonance microscopy. Stroke. 1992;23:746-754.
24. Sevick RJ, Kanda F, Mintorovitch J, Arieff AI, Kucharczyk J, Tsuruda JS, Norman D, Moseley ME. Cytotoxic brain edema: assessment with diffusion-weighted MR imaging. Radiology. 1992;185:687-690.
25. Busza AL, Allen KL, King MD, van Bruggen N, Williams SR, Gadian DG. Diffusion-weighted imaging studies of cerebral ischemia in gerbils: potential relevance to energy failure. Stroke. 1992;23: 1602-1612.
26. Lo EH, Pierce AR, Mandeville JB, Rosen BR. Neuroprotection with NBQX in rat focal cerebral ischemia: effects on ADC probability distribution functions and diffusion-perfusion relationships. Stroke. 1997;28:439-446.
27. Tatlisumak T, Takano K, Carano RA, Fisher M. Effect of basic fibroblast growth factor on experimental focal ischemia studied by diffusion-weighted and perfusion imaging. Stroke. 1996;27: 2292-2297.
28. Yenari MA, Palmer JT, Sun GH, de Crespigny A, Moseley ME, Steinberg GK. Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI. Brain Res. 1996;739:36-45.
29. Zhang Z, Zhang RL, Jiang Q, Raman SB, Cantwell L, Chopp M. A new rat model of thrombotic focal cerebral ischemia. J Cereb Blood Flow Metab. 1997;17:123-135.
30. Takano K, Carano RA, Tatlisumak T, Meiler M, Sotak CH, Kleinert HD, Fisher M. The efficacy of intraarterial and intravenous prourokinase in an embolic stroke model evaluated by diffusion-perfusion magnetic resonance imaging. Neurology. 1998;50:870-875.
31. Minematsu K, Fisher M, Li L, Sotak CH. Diffusion and perfusion magnetic resonance imaging studies to evaluate a noncompetitive N-methyl-D-aspartate antagonist and reperfusion in experimental stroke in rats. Stroke. 1993;24:2074-2081.
32. Minematsu K, Fisher M, Li L, Davis MA, Knapp AG, Cotter RE, McBurney RN, Sotak CH. Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI. Neurology. 1993;43:397-403.
33. Knight RA, Dereski MO, Helpern JA, Ordidge RJ, Chopp M. Magnetic resonance imaging assessment of evolving focal cerebral ischemia: comparison with histopathology in rats. Stroke. 1994;25: 1252-1261.
34. van Bruggen N, Cullen BM, King MD, Doran M, Williams SR, Gadian DG, Cremer JE, T2-and diffusion-weighted magnetic resonance imaging of a focal ischemic lesion in rat brain. Stroke. 1992; 23:576-582.
35. Minematsu K, Li L, Fisher M, Sotak CH, Davis MA, Fiandaca MS. Diffusion-weighted magnetic resonance imaging: rapid and quantitative detection of focal brain ischemia. Neurology. 1992;42:235-240.
36. Roberts TP, Vexler Z, Derugin N, Moseley ME, Kucharczyk J. High-speed MR imaging of ischemic brain injury following stenosis of the middle cerebral artery. J Cereb Blood Flow Metab. 1993;13: 940-946.
37. Baird AE, Benfield A, Schlaug G, Siewert B, Lovblad KO, Edelman RR, Warach S. Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging. Ann Neurol. 1997;41:581-589.
38. Baird AE, Austin MC, McKay WJ, Donnan GA. Changes in cerebral tissue perfusion during the first 48 hours of ischaemic stroke: relation to clinical outcome. J Neurol Neurosurg Psychiatry. 1996;61:26-29.
39. Warach S, Dashe JF, Edelman RR. Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: a preliminary analysis. J Cereb Blood Flow Metab. 1996;16:53-59.
40. Tong DC, Yenari MA, Albers GW, O'Brien M, Marks MP, Moseley ME. Correlation of perfusion-and diffusion-weighted MRI with NIHSS score in acute (<6.5 hour) ischemic stroke. Neurology. 1998; 50:864-870.
41. Saunders DE, Clifton AG, Brown MM. Measurement of infarct size using MRI predicts prognosis in middle cerebral artery infarction. Stroke. 1995;26:2272-2276.
42. Lovblad KO, Baird AE, Schlaug G, Benfield A, Siewert B, Voetsch B, Connor A, Burzynski C, Edelman RR, Warach S. Ischemic lesion volumes in acute human stroke correlated with clinical severity and outcome: a diffusion-weighted MRI study. Ann Neurol. 1997;42: 164-170.
43. Barber PA, Darby DG, Desmond PM, Yang Q, Gerraty RP, Jolley D, Donnan GA, Tress BM, Davis SM. Prediction of stroke outcome with echoplanar perfusion-and diffusion-weighted MRI. Neurology. 1998; 51:418-426.
44. Sorensen AG, Tievsky AL, Ostergaard L, Weisskoff RM, Rosen BR. Contrast agents in functional MR imaging. J Magn Resort Imaging. 1997;7:47-55.
45. Patel MR, Siewert B, Warach S, Edelman RR. Diffusion and perfusion imaging techniques. Magn Reson Imaging Clin N Am. 1995;3: 425-438.
46. Yenari MA, de Crespigny A, Palmer JT, Roberts S, Schrier SL, Albers GW, Moseley ME, Steinberg GK. Improved perfusion with rt-PA and hirulog in a rabbit model of embolic stroke. J Cereb Blood Flow Metab. 1997;17:401-411.
47. Muller TB, Haraldseth O, Jones RA, Sebastiani G, Godtliebsen F, Lindboe CF, Unsgard G. Combined perfusion and diffusion-weighted magnetic resonance imaging in a rat model of reversible middle cerebral artery occlusion. Stroke. 1995;26:451-457.
48. Marks MP, Tong DC, Beaulieu C, Albers GW, de Crespigny A, Moseley ME. Evaluation of early reperfusion and IV tPA therapy using diffusion-and perfusion-weighted MRI. Neurology. 1999;52: 1792-1798.
49. Quast MJ, Huang NC, Hillman GR, Kent TA. The evolution of acute stroke recorded by multimodal magnetic resonance imaging. Magn Reson Imaging. 1993;11:465-471.
50. Rordorf G, Koroshetz WJ, Copen WA, Cramer SC, Schaefer PW, Budzik RF Jr, Schwamm LH, Buonanno F, Sorensen AG, Gonzalez G. Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI. Stroke. 1998;29:939-943.
51. Darby DG, Barber PA, Desmond PM, Yang Q, Gerraty RP, Tress BM, Davis SM. Patterns and frequency of acute ischemic stroke topography as depicted by combined perfusion-and diffusion-weighted magnetic resonance imaging. Stroke. 1999;30:235. Abstract.
52. Caplan LR, Mohr JP, Kistler JP, Koroshetz W. Should thrombolytic therapy be the first-line treatment for acute ischemic stroke? Thrombolysis: not a panacea for ischemic stroke. N Engl J Med. 1997;337: 1309-1310.
53. Marks MP, de Crespigny A, Lentz D, Enzmann DR, Albers GW, Moseley ME. Acute and chronic stroke: navigated spin-echo diffusion-weighted MR imaging. Radiology. 1996;199:403-408.
54. Caplan LR. Stroke thrombolysis: growing pain. Mayo Clin Proc. 1997;72:1090-1092.
55. r 55. Beaulieu C, DeCrespigny A, Tong D, Moseley M, Albers G, Marks M. Longitudinal MRI study of perfusion and diffusion in stroke: evolution of lesion volume and correlation with clinical outcome. Ann Neurol. In press.
56. Wardlaw J, Warlow, CP. Thrombolysis in acute ischemic stroke: does it work? Stroke. 1992;23:1826-1837.
57. Patel MR, Edelman RR, Warach S. Detection of hyperacute primary intraparenchymal hemorrhage by magnetic resonance imaging. Stroke. 1996;27:2321-2324.
58. Schellinger PD, Jansen O, Fiebach JB, Hacke W, Sartor K. A standardized MRI stroke protocol: comparison with CT in hyperacute intracerebral hemorrhage. Stroke. 1999;30:765-768.
59. Singer MB, Atlas SW, Drayer BP. Subarachnoid space disease: diagnosis with fluid-attenuated inversion-recovery MR imaging and comparison with gadolinium-enhanced spin-echo MR imaging: blinded reader study. Radiology. 1998;208:417-422.
60. Roob G, Schmidt R, Kapeller P, Lechner A, Hartung HP, Fazekas F. MRI evidence of past cerebral microbleeds in a healthy elderly population. Neurology. 1999;52:991-994.
61. Wijdicks EF, Jack, Jr. CR. Intracerebral hemorrhage after fibrinolytic therapy for acute myocardial infarction. Stroke. 1993;24:554-557.
62. Albers GW, Lansberg MG, Norbash AM, Woolfenden AR, O'Brien MW, Tong DC, Marks MP, Kemp SM, Moseley ME. Yield of diffusion weighted MRI for detection of potentially clinically relevant findings in stroke patients. Stroke. 1999;30:235. Abstract.