Generalized Anxiety Disorder

Southern Medical Journal

Volumn 96, Issue 6, 2003, Pages 581-586

  Pary, Raymond ^a,b   Matuschka, Paul R ^a   Lewis, Susan ^a   Caso, William ^a   Lippmann, Steven ^a  

^a University of Louisville School of Medicine   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; AMFEBUTAMONE; AMPHETAMINE; ANTIDEPRESSANT AGENT; BENZODIAZEPINE; BRONCHODILATING AGENT; BUSPIRONE; CENTRAL STIMULANT AGENT; COCAINE; CORTICOSTEROID; DECONGESTIVE AGENT; DIAZEPAM; FLUOXETINE; GINSENG EXTRACT; HERBACEOUS AGENT; HYPERICUM PERFORATUM EXTRACT; HYPERTENSIVE FACTOR; ISOPRENALINE; LEVOTHYROXINE; MEPREDNISONE; METHYLPHENIDATE; METHYLXANTHINE; NORADRENALIN UPTAKE INHIBITOR; PREDNISONE; PSEUDOEPHEDRINE; SALBUTAMOL; SEROTONIN UPTAKE INHIBITOR; THEOPHYLLINE; THYROID HORMONE; UNINDEXED DRUG;

CLINICAL TRIAL; COGNITIVE DEFECT; CONCENTRATION LOSS; DISTRESS SYNDROME; DRUG DEPENDENCE; DRUG TOLERANCE; FATIGUE; FEEDBACK SYSTEM; GENERALIZED ANXIETY DISORDER; HUMAN; IRRITABILITY; MUSCLE TONE; PSYCHOMOTOR DISORDER; PSYCHOTHERAPY; RESTLESSNESS; REVIEW; SLEEP DISORDER; WITHDRAWAL SYNDROME; ANXIETY DISORDER; CHRONIC DISEASE; RISK FACTOR;

ANXIETY DISORDERS; CHRONIC DISEASE; HUMANS; RISK FACTORS;

EID: 0042885715     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.SMJ.0000054499.21994.A5     Document Type: Review

References (41)

1. Rosenbaum JF, Pollack MH, Otto MW, Bernstein JG. Anxious patients, in Cassem NH, Stern TA, Rosenbaum JF, Jellinek MS (eds): Massachusetts General Hospital Handbook of General Psychiatry. St. Louis, Mosby-Year Book, 1997, ed 4, pp 173-210.
2. Lewis S. Anxiety, in Harkreader H (ed): Fundamentals of Nursing: Caring and Clinical Judgment. Philadelphia, W.B. Saunders Co., 2000, pp 1310-1328.
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR. Washington, DC, American Psychiatric Association, 2000, ed 4 text rev, pp 436-476.
4. Wittchen HU, Hoyer J. Generalized anxiety disorder: Nature and course. J Clin Psychiatry 2001;62(Suppl 11):15-19.
5. Carter RM, Wittchen HU, Phister H, Kessler RC. One-year prevalence of subthreshold and threshold DSM-IV generalized anxiety disorder in a nationally representative sample. Depress Anxiety 2001;13:78-88.
6. Olfson M, Broadhead WE, Weissmann MM, Leon AC, Farber L, Hoven C, et al. Subthreshold psychiatric symptoms in a primary care group practice. Arch Gen Psychiatry 1996;53:880-886.
7. Dugas MJ, Gagnon F, Ladouceur R, Freeston MH. Generalized anxiety disorder: A preliminary test of a conceptual model. Behav Res Ther 1998;36:215-226.
8. Nutt DJ. Neurobiological mechanisms in generalized anxiety disorder. J Clin Psychiatry 2001;62(Suppl 11):22-27.
9. Krystal JH, D'Souza DC, Sanacora G, Goddard AW, Charney DS. Current perspectives on the pathophysiology of schizophrenia, depression, and anxiety disorders. Med Clin North Am 2001;85:559-577.
10. Nutt DJ, Glue P, Lawson C, Wilson S. Flumazenil provocation of panic attacks: Evidence for altered benzodiazepine receptor sensitivity in panic disorder. Arch Gen Psychiatry 1990;47:917-925.
11. Davis M, Rainnie D, Cassell M. Neurotransmission in the rat amygdala related to fear and anxiety. Trends Neurosci 1994;17:208-214.
12. Bradwejn J. CCK agonists and antagonists in clinical studies of panic and anxiety. Clin Neuropharmacol 1992;15:481A-482A.
13. Bremner JD, Licinio J, Darnell A, Krystal JH, Owens MJ, Southwick SM, et al. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Am J Psychiatry 1997;154:624-629.
14. Reynolds CF III, Shaw DH, Newton TF, Coble PA, Kupfer DJ. EEG sleep in outpatients with generalized anxiety: A preliminary comparison with depressed outpatients. Psychiatry Res 1983;8:81-89.
15. Saletu-Zyhlarz G, Saletu B, Anderer P, Brandstatter N, Frey R, Gruber G, et al. Nonorganic insomnia in generalized anxiety disorder. 1. controlled studies on sleep, awakening and daytime vigilance utilizing polysomnography and EEG mapping. Neuropsychobiology 1997;36:117-129.
16. Thase ME, Simons AD, Reynolds CF III. Abnormal electroencephalographic sleep profiles in major depression: Association with response to cognitive behavior therapy. Arch Gen Psychiatry 1996;53:99-108.
17. Gratacos M, Nadal M, Martin-Santos R, Pujana MA, Gago J, Peral B, et al. A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders. Cell 2001;106:367-379.
18. Rickels K, Rynn MA. What is generalized anxiety disorder? J Clin Psychiatry 2001;62(Suppl 11):4-12.
19. Judd LL, Kessler RC, Paulus MP, Zeller PV, Wittchen HU, Kunovac JL. Comorbidity as a fundamental feature of generalized anxiety disorders: Results from the National Comorbidity Study (NCS). Acta Psychiatr Scand Suppl 1998;393:6-11.
20. Wittchen HU, Zhao S, Kessler RC, Eaton WW. DSM-III-R generalized anxiety disorder in the National Comorbidity Survey. Arch Gen Psychiatry 1994;51:355-364.
21. Lenze EJ, Mulsant BH, Shear MK, Schulberg HC, Dew MA, Begley AE, et al. Comorbid anxiety disorders in depressed elderly patients. Am J Psychiatry 2000;157:722-728.
22. Mendlowicz MV, Stein MB. Quality of life in individuals with anxiety disorders. Am J Psychiatry 2000;157:669-682.
23. Ballenger. Treatment of anxiety disorders to remission. J Clin Psychiatry 2001;62(Suppl 12):5-9.
24. Silverman WK, Saavedra LM, Pina AA. Test-retest reliability of anxiety symptoms and diagnosis with the Anxiety Disorders Interview Schedule for DSM-IV: Child and parent versions. J Am Acad Child Adolesc Psychiatry 2001;40:937-944.
25. Borkovec TD, Ruscio AM. Psychotherapy for generalized anxiety disorder. J Clin Psychiatry 2001;62(Suppl 11):37-45.
26. Lenz G, Dermal U. Quality of life in depression and anxiety disorders: An exploratory follow-up study after intensive inpatient cognitive behavior therapy, Psychopathology 2000;33:297-302.
27. Young AS, Klap R, Sherbourne CD, Wells KB. The quality of care for depressive and anxiety disorders in the United States. Arch Gen Psychiatry 2001;58:55-61.
28. Salzman C, Goldenberg I, Bruce SE, Keller MB. Pharmacologic treatment of anxiety disorders in 1989 versus 1996: Results from the Harvard/Brown anxiety disorders research program. J Clin Psychiatry 2001; 62:149-152.
29. Davidson JRT. Pharmacotherapy of generalized anxiety disorder. J Clin Psychiatry 2001;2(Suppl 11):46-50.
30. Lydiard RB, Laraia MT, Ballenger JC, Howell EF. Emergence of depressive symptoms in patients receiving alprazolam for panic disorder. Am J Psychiatry 1987;144:664-665.
31. Rickels K, Downing R, Schweizer E, Hassman H. Antidepressants for the treatment of generalized anxiety disorder: A placebo-controlled comparison of imipramine, trazodone and diazepam. Arch Gen Psychiatry 1993;50:884-895.
32. Davidson JR, DuPont RL, Hedges D, Haskins JT. Efficacy, safety, and tolerability of venlafaxine extended release and buspirone in outpatients with generalized anxiety disorder. J Clin Psychiatry 1999;60:528-535.
33. Rocca P, Fonzo V, Scotta M, Zanalda E, Ravizza L. Paroxetine efficacy in the treatment of generalized anxiety disorder. Acta Psychiatr Scand 1997;95:444-450.
34. Wylie ME, Miller MD, Shear MK, Little JT, Mulsant BH, Pollock BG, et al. Fluvoxamine pharmacotherapy of anxiety disorders in later life: Preliminary open-trial data. J Geriatr Psychiatry Neurol 2000;13:43-48.
35. Williams T, Hodgman C. Medication for the management of anxiety disorders in children and adolescents. Pediatr Ann 2001;30:146-153.
36. The Research Unit on Pediatric Psychopharmacology Anxiety Study Group. Fluvoxamine for the treatment of anxiety disorders in children and adolescents. N Engl J Med 2001;344:1279-1285, 1326-1327.
37. Gelenberg AJ, Lydiard RB, Rudolph RL, Aguiar L, Haskins JT, Salinas E. Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: A 6-month randomized controlled trial. JAMA 2000;283:3082-3088.
38. Eison AS, Eison MS. Serotonergic mechanisms in anxiety. Prog Neuropsychopharmacol Biol Psychiatry 1994;18:47-62.
39. Norton JW, Quarles E. Gabapentin and anxiety. Hosp Pharm 2001;36: 843-845.
40. McEvoy GK. AHFS Drug Information 2001. Bethesda, MD, American Society of Health-System Pharmacists, 2001, pp 2094-2097.
41. Chouinard G, Beauclair L, Bélanger MC. Gabapentin: Long-term antianxiety and hypnotic effects in psychiatric patients with comorbid anxiety-related disorders. Can J Psychiatry 1998;43:305.