The use of gating technology in bioengineering insulin-secreting cells from embryonic stem cells

Cytotechnology

Volumn 41, Issue 2-3, 2003, Pages 145-151

  Roche, Enrique ^a   Burcin, Mark M ^b   Esser, Sybille ^b   Rüdiger, Manfred ^b   Soria, Bernat ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b Cardion AG   (Germany)

Author keywords

Antibiotic selection; Cell therapy; Diabetes mellitus; Embryonic stem cells; Endocrine pancreas; Gating technology; Pancreatic cell

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; DNA; GREEN FLUORESCENT PROTEIN; INSULIN; LEUKEMIA INHIBITORY FACTOR;

ANIMAL CELL; CELL DIFFERENTIATION; CELL TYPE; CONFERENCE PAPER; DIABETES MELLITUS; EMBRYO; EMBRYO CELL; FETUS; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMAN; HUMAN CELL; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; STEM CELL; TECHNOLOGY; TRANSGENIC ANIMAL;

ANIMALIA;

EID: 0042883971     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024878807264     Document Type: Conference Paper

References (31)

1. Baumann RP, Sherman DH, Sartorelli AC (2002) Novel selection marker for mammalian cell transfection. BioTechniques 32: 1030-1036.
2. Bonner-Weir S, Taneja M, Weir GC, Tatarkiewicz K, Song K, Sharma A & O'Neil JJ (2000) In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci USA 97: 7999-8004.
3. Brook FA & Gardner RL (1997) The origin and efficient derivation of embryonic stem cells in the mouse. Proc Natl Acad Sci USA 94: 5709-5712.
4. Culver KW & Blaese RM (1994) Gene therapy for cancer. Trends in Genetics 10: 174-178.
5. Edlund H (2001) Developmental biology of the pancreas. Diabetes 50 (Suppl 1): S5-S9.
6. Efrat S (1998) Prospects for gene therapy of insulin-dependent diabetes mellitus. Diabetologia 41: 1401-1409.
7. Efrat S, Fusco-DeMane D, Lemberg H, Emran OA & Wang, S (1995) Conditional transformation of a pancreatic β-cell line derived form transgenic mice expressing a tetracycline-regulated oncogene. Proc Natl Acad Sci USA 92: 3576-3580.
8. Fuhrmann-Benzakein E, García-Gabay I, Pepper MS, Vassalli JD & Herrera PL (2000) Inducible and irreversible control of gene expression using a single transgene. Nucleic Acid Res 28: E99.
9. Goldfine ID, German MD, Tseng HC, Wang J, Bolaffi JL, Chen JW, Olson DC & Rothman SS (1997). The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract. Nat Biotechnol 15: 1378-1382.
10. Gossen M & Bujard H (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89: 5547-5551.
11. Gros L, Montoliu R, Riu E, Lebrigand L & Bosch F (1998) Regulated production of mature insulin by non-beta cells. Human Gene Therapy 8: 2249-2259.
12. Jensen J, Heller RS, Funder-Nielsen T, Pedersen EE, Lindsell C, Weinmaster G, Madsen OD & Serup P (2000) Independent development of pancreatic α- and β-cells from neurogenin3-expressing precursors. A role for the Notch pathway in repression of premature differentiation. Diabetes 49: 163-176.
13. Keyoung HM, Roy NS, Benraiss A, Louissaint Jr A, Suzuki A, Hashimoto M, Rashbaum WK, Okano H & Goldman SA (2001) High-yield selection and extraction of two promoter-defined phenotypes of neuronal stem cells from the fetal human brain. Nature Biotechnol 19: 843-850.
14. Klug MG, Soonpa MH, Koh GY & Field LJ (1996) Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J Clin Invest 98: 216-224.
15. Kolossov E, Fleischmann BK & Liu Q et al (1998) Functional characteristics of embryonic stem cell-derived cardiac precursors cells identified by tissue-specific expression of the green fluorescent protein. J Cell Biol 143: 2045-2056.
16. Li M, Pevny L, Lovell-Badge R, Smith A (1998) Generation of purified neural precursors from embryonic stem cells by lineage selection. Curr Biol 8: 971-974.
17. Müller M, Fleischmann BK, Selbert S, JI GJ, Endl E, Middeler G, Müller OJ, Schlenke P, Frese S, Wobus AM, Hescheler J, Katus HA & Franz WM (2000) Selection of ventricular-like cardiomyocytes from ES cells in vitro. FASEB J 14: 2540-2548.
18. Odorico JS, Kaufman DS & Thomson JA (2001) Multilineage differentiation from human embryonic stem cell lines. Stem Cells 19: 193-204.
19. Pevny LH, Sockanathan S, Placzek M & Lovell-Badge R (1998) A role for Sox1 in neural determination. Development 125: 1967-1978.
20. Reubinoff BE, Pera MF, Fong C-Y, Trounson A & Bongso A (2000) Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nature Biotechnol 18: 399-404.
21. Richards M, Fong C-Y, Chan W-K, Wong P-C & Bongso A (2002) Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells. Nature Biotechnol 20: 933-936.
22. Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA & Benvenisty N (2000) Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci USA 97: 11307-11312.
23. Shapiro AMJ, Lakey JRT, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM & Rajotte RV (2000) Islet transplantation in seven patients with type 1 diabetes mellitus using a corticoid-free immunosuppressive regime. N Eng J Med 343: 230-238.
24. Smith AG (1991) Culture and differentiation of embryonic stem cells. J Tissue Culture Methods 13: 89-94.
25. Soria B, Andreu E, Berná G, Fuentes E, Gil A, León-Quinto T, Martín F, Montanya E, Nadal A, Reig JA, Ripoll C, Roche E, Sánchez-Andrés JV & Segura J (2000a) Engineering pancreatic islets. Pflügers Arch-Eur J Physiol 440: 1-18.
26. Soria B, Roche E, Berná G, León-Quinto T, Reig JA & Martin F (2000b) Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49: 157-162.
27. Soria B (2001) In-vitro differentiation of pancreatic β-cells. Differentiation 68: 205-219.
28. Soria B, Skoudy A & Martín F (2001) From stem cells to beta cells: new strategies in cell therapy of diabetes mellitus. Diabetologia 44: 407-415.
29. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS & Jones JM (1998) Embryonic stem cell lines derived from human blastocysts. Science 282: 1145-1147.
30. Weiss MJ & Orkin SH (1996) In vitro differentiation of murine embryonic stem cells. New approaches to old problems. J Clin Invest 97: 591-595.
31. Xu C, Inokuma MS, Denham J, Golds K, Kundu P, Gold JD & Carpenter MK (2001) Feeder-free growth of undifferentiated human embryonic stem cells. Nature Biotechnol 19: 971-974.