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Volumn 105, Issue 3, 2003, Pages 373-382

Expression and coordinated regulation of matrix metalloproteinases in chronic hepatitis C and hepatitis C virus-induced liver cirrhosis

Author keywords

Cirrhosis; Fibrogenesis; Hepatitis C; Matrix remodelling; Metalloproteinase (MMP); Tissue inhibitor of metalloproteinases (TIMP)

Indexed keywords

COLLAGENASE 3; ENZYME PRECURSOR; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; STROMELYSIN; STROMELYSIN 2; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

EID: 0042877150     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20030098     Document Type: Article
Times cited : (79)

References (45)
  • 1
    • 0032774537 scopus 로고    scopus 로고
    • Pathobiology of hepatic stellate cells
    • Burt, A. D. (1999) Pathobiology of hepatic stellate cells. J. Gastroenterol. 34, 299-304
    • (1999) J. Gastroenterol. , vol.34 , pp. 299-304
    • Burt, A.D.1
  • 2
    • 0029997830 scopus 로고    scopus 로고
    • Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: A key event in hepatic fibrogenesis
    • Gressner, A. M. (1996) Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis. Kidney Int. Suppl. 54, S39-45
    • (1996) Kidney Int. Suppl. , vol.54
    • Gressner, A.M.1
  • 3
    • 0032801286 scopus 로고    scopus 로고
    • Liver fibrogenesis and the role of hepatic stellate cells: New insights and prospects for therapy
    • Li, D. and Friedman, S. L. (1999) Liver fibrogenesis and the role of hepatic stellate cells: new insights and prospects for therapy. J. Gastroenterol. Hepatol. 14, 618-633
    • (1999) J. Gastroenterol. Hepatol. , vol.14 , pp. 618-633
    • Li, D.1    Friedman, S.L.2
  • 4
    • 0032211577 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrogenesis
    • Olaso, E. and Friedman, S. L. (1998) Molecular regulation of hepatic fibrogenesis. J. Hepatol. 29, 836-847
    • (1998) J. Hepatol. , vol.29 , pp. 836-847
    • Olaso, E.1    Friedman, S.L.2
  • 5
    • 0033618337 scopus 로고    scopus 로고
    • Matrix metalloproteinases
    • Nagase, H. and Woessner, Jr, J. F. (1999) Matrix metalloproteinases. J. Biol. Chem. 274, 21491-21494
    • (1999) J. Biol. Chem. , vol.274 , pp. 21491-21494
    • Nagase, H.1    Woessner J.F., Jr.2
  • 6
    • 0036516460 scopus 로고    scopus 로고
    • Matrix metalloproteinases: A tail of a frog that became a prince
    • Brinckerhoff, C. E. and Matrisian, L. M. (2002) Matrix metalloproteinases: a tail of a frog that became a prince. Nat. Rev. Mol. Cell. Biol. 3, 207-214
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 207-214
    • Brinckerhoff, C.E.1    Matrisian, L.M.2
  • 7
    • 0030717692 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
    • Gomez, D. E., Alonso, D. F., Yoshiji, H. and Thorgeirsson, U. P. (1997) Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur. J. Cell Biol. 74, 111-122
    • (1997) Eur. J. Cell Biol. , vol.74 , pp. 111-122
    • Gomez, D.E.1    Alonso, D.F.2    Yoshiji, H.3    Thorgeirsson, U.P.4
  • 8
    • 0034615550 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: Evolution, structure and function
    • Brew, K., Dinakarpandian, D. and Nagase, H. (2000) Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim. Biophys. Acta 1477, 267-283
    • (2000) Biochim. Biophys. Acta , vol.1477 , pp. 267-283
    • Brew, K.1    Dinakarpandian, D.2    Nagase, H.3
  • 9
    • 0029024766 scopus 로고
    • Collagenases and liver fibrosis
    • Arthur, M. J. P. (1995) Collagenases and liver fibrosis. J. Hepatol. 22, 43-48
    • (1995) J. Hepatol. , vol.22 , pp. 43-48
    • Arthur, M.J.P.1
  • 10
    • 0030768282 scopus 로고    scopus 로고
    • Matrix degradation in liver: A role in injury and repair
    • Arthur, M. J. P. (1997) Matrix degradation in liver: a role in injury and repair. Hepatology 26, 1069-1071
    • (1997) Hepatology , vol.26 , pp. 1069-1071
    • Arthur, M.J.P.1
  • 11
    • 0025784806 scopus 로고
    • Temporal and spatial patterns of transin/stromelysin RNA expression following toxic injury in rat liver
    • Herbst, H., Heinrichs, O., Schuppan, D., Milani, S. and Stein, H. (1991) Temporal and spatial patterns of transin/stromelysin RNA expression following toxic injury in rat liver. Virchows Arch. B: 60, 295-300
    • (1991) Virchows Arch. B , vol.60 , pp. 295-300
    • Herbst, H.1    Heinrichs, O.2    Schuppan, D.3    Milani, S.4    Stein, H.5
  • 12
    • 0033061790 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-13 and tissue inhibitor of metalloproteinase-1 in acute liver injury
    • Yata, Y., Takahara, T., Furui, K., Zhang, L. P. and Watanabe, A. (1999) Expression of matrix metalloproteinase-13 and tissue inhibitor of metalloproteinase-1 in acute liver injury. J. Hepatol. 30, 419-424
    • (1999) J. Hepatol. , vol.30 , pp. 419-424
    • Yata, Y.1    Takahara, T.2    Furui, K.3    Zhang, L.P.4    Watanabe, A.5
  • 13
    • 0031740778 scopus 로고    scopus 로고
    • Altered balance between matrix metalloproteinases and their inhibitors in experimental billary fibrosis
    • Kossakowska, A. E., Edwards, D. R., Lee, S. S. et al. (1998) Altered balance between matrix metalloproteinases and their inhibitors in experimental billary fibrosis. Am. J. Pathol. 153, 1895-1902
    • (1998) Am. J. Pathol. , vol.153 , pp. 1895-1902
    • Kossakowska, A.E.1    Edwards, D.R.2    Lee, S.S.3
  • 14
    • 0030030039 scopus 로고    scopus 로고
    • Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver
    • Benyon, R. C., Iredale, J. P., Goddard, S., Winwood, P. J. and Arthur, M. J. P. (1996) Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver. Gastroenterology 110, 821-831
    • (1996) Gastroenterology , vol.110 , pp. 821-831
    • Benyon, R.C.1    Iredale, J.P.2    Goddard, S.3    Winwood, P.J.4    Arthur, M.J.P.5
  • 15
    • 0028291795 scopus 로고
    • Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver
    • Milani, S., Herbst, H., Schuppan, D. et al. (1994) Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am. J. Pathol. 144, 528-537
    • (1994) Am. J. Pathol. , vol.144 , pp. 528-537
    • Milani, S.1    Herbst, H.2    Schuppan, D.3
  • 16
    • 0030934411 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis
    • Herbst, H., Wege, T., Milani, S. et al. (1997) Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis. Am. J. Pathol. 150, 1647-1659
    • (1997) Am. J. Pathol. , vol.150 , pp. 1647-1659
    • Herbst, H.1    Wege, T.2    Milani, S.3
  • 17
    • 0035119323 scopus 로고    scopus 로고
    • Matrix metalloproteinase (MMP)-2, MMP-7, and tissue inhibitor of metalloproteinase-1 are closely related to the fibroproliferative process in the liver during chronic hepatitis C
    • Lichtinghagen, R., Michels, D., Haberkorn, C. I. et al. (2001) Matrix metalloproteinase (MMP)-2, MMP-7, and tissue inhibitor of metalloproteinase-1 are closely related to the fibroproliferative process in the liver during chronic hepatitis C. J. Hepatol. 34, 239-247
    • (2001) J. Hepatol. , vol.34 , pp. 239-247
    • Lichtinghagen, R.1    Michels, D.2    Haberkorn, C.I.3
  • 18
    • 0032903365 scopus 로고    scopus 로고
    • Matrix metalloproteinases in liver and serum in chronic active hepatitis C and HCV-induced cirrhosis
    • Lichtinghagen, R., Steinmetz, C., Pehle, B., Breitenstein, K., Seifert, T. and Boeker, K. H. W. (1999) Matrix metalloproteinases in liver and serum in chronic active hepatitis C and HCV-induced cirrhosis. Hepatol. Res. 14, 119-134
    • (1999) Hepatol. Res. , vol.14 , pp. 119-134
    • Lichtinghagen, R.1    Steinmetz, C.2    Pehle, B.3    Breitenstein, K.4    Seifert, T.5    Boeker, K.H.W.6
  • 19
    • 0029039362 scopus 로고
    • Histological grading and staging of chronic hepatitis
    • Ishak, K., Baptista, A., Bianchi, L. et al. (1995) Histological grading and staging of chronic hepatitis. J. Hepatol. 22, 696-699
    • (1995) J. Hepatol. , vol.22 , pp. 696-699
    • Ishak, K.1    Baptista, A.2    Bianchi, L.3
  • 20
    • 0030774552 scopus 로고    scopus 로고
    • Analytical aspects regarding the measurement of metalloproteinases and their inhibitors in blood
    • Lein, M., Nowak, L., Jung, K. et al. (1997) Analytical aspects regarding the measurement of metalloproteinases and their inhibitors in blood. Clin. Biochem. 30, 491-496
    • (1997) Clin. Biochem. , vol.30 , pp. 491-496
    • Lein, M.1    Nowak, L.2    Jung, K.3
  • 21
    • 0031899582 scopus 로고    scopus 로고
    • Kind of sample as preanalytical determinant of matrix metalloproteinase 2 and 9 and tissue inhibitor of metalloproteinase 2 in blood
    • Jung, K., Laube, C., Lein, M. et al. (1998) Kind of sample as preanalytical determinant of matrix metalloproteinase 2 and 9 and tissue inhibitor of metalloproteinase 2 in blood. Clin. Chem. 44, 1060-1062
    • (1998) Clin. Chem. , vol.44 , pp. 1060-1062
    • Jung, K.1    Laube, C.2    Lein, M.3
  • 24
    • 0033968058 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C
    • Lichtinghagen, R., Huegel, O., Seifert, T. et al. (2000) Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C. Clin. Chem. 46, 183-192
    • (2000) Clin. Chem. , vol.46 , pp. 183-192
    • Lichtinghagen, R.1    Huegel, O.2    Seifert, T.3
  • 25
    • 0028987680 scopus 로고
    • Preliminary report: Genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis
    • Ye, S., Watts, G. F., Mandalia, S., Humphries, S. E. and Henney, A. M. (1995) Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis. Br. Heart J. 73, 209-215
    • (1995) Br. Heart J. , vol.73 , pp. 209-215
    • Ye, S.1    Watts, G.F.2    Mandalia, S.3    Humphries, S.E.4    Henney, A.M.5
  • 26
    • 84955819402 scopus 로고
    • Identification of Bordetella pertussis in nasopharyngeal swabs using the polymerase chain reaction: Evaluation of detection methods
    • Lichtinghagen, R., Diedrich-Glaubitz, R. and von Horsten, B. (1994) Identification of Bordetella pertussis in nasopharyngeal swabs using the polymerase chain reaction: evaluation of detection methods. Eur. J. Clin. Chem. Clin. Biochem. 32, 161-167
    • (1994) Eur. J. Clin. Chem. Clin. Biochem. , vol.32 , pp. 161-167
    • Lichtinghagen, R.1    Diedrich-Glaubitz, R.2    Von Horsten, B.3
  • 27
    • 0019430857 scopus 로고
    • Chi-square test for contingency tables
    • Kirkwood, B. R. (1981) Chi-square test for contingency tables. Br. J. Hosp. Med. 25, 291-292
    • (1981) Br. J. Hosp. Med. , vol.25 , pp. 291-292
    • Kirkwood, B.R.1
  • 28
    • 0016343603 scopus 로고
    • Collagenase activity in experimental hepatic fibrosis
    • Okazaki, I. and Maruyama, K. (1974) Collagenase activity in experimental hepatic fibrosis. Nature (London) 252, 49-50
    • (1974) Nature (London) , vol.252 , pp. 49-50
    • Okazaki, I.1    Maruyama, K.2
  • 29
    • 0018104310 scopus 로고
    • Collagenase in experimental carbon tetrachloride cirrhosis of the liver
    • Montfort, I. and Perez-Tamayo, R. (1978) Collagenase in experimental carbon tetrachloride cirrhosis of the liver. Am. J. Pathol. 92, 411-420
    • (1978) Am. J. Pathol. , vol.92 , pp. 411-420
    • Montfort, I.1    Perez-Tamayo, R.2
  • 30
    • 0019984548 scopus 로고
    • Mammalian collagenase increases in early alcoholic liver disease and decreases with cirrhosis
    • Maruyama, K., Feinman, L., Fainsilber, Z., Nakano, M., Okazaki, I. and Lieber, C. S. (1982) Mammalian collagenase increases in early alcoholic liver disease and decreases with cirrhosis. Life Sci. 30, 1379-1384
    • (1982) Life Sci. , vol.30 , pp. 1379-1384
    • Maruyama, K.1    Feinman, L.2    Fainsilber, Z.3    Nakano, M.4    Okazaki, I.5    Lieber, C.S.6
  • 31
    • 0023575601 scopus 로고
    • Collagenolytic activity in experimental cirrhosis of the liver
    • Perez-Tamayo, R., Montfort, I. and Gonzalez, E. (1987) Collagenolytic activity in experimental cirrhosis of the liver. Exp. Mol. Pathol. 47, 300-308
    • (1987) Exp. Mol. Pathol. , vol.47 , pp. 300-308
    • Perez-Tamayo, R.1    Montfort, I.2    Gonzalez, E.3
  • 32
    • 0029888478 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
    • Iredale, J. P., Benyon, R. C., Arthur, M. J. P. et al. (1996) Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 24, 176-184
    • (1996) Hepatology , vol.24 , pp. 176-184
    • Iredale, J.P.1    Benyon, R.C.2    Arthur, M.J.P.3
  • 33
    • 0026720588 scopus 로고
    • Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver
    • Iredale, J. P., Murphy, G., Hembry, R. M., Friedman, S. L. and Arthur, M. J. P. (1992) Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver. J. Clin. Invest. 90, 282-287
    • (1992) J. Clin. Invest. , vol.90 , pp. 282-287
    • Iredale, J.P.1    Murphy, G.2    Hembry, R.M.3    Friedman, S.L.4    Arthur, M.J.P.5
  • 34
    • 0028906431 scopus 로고
    • Increased expression of matrix metalloproteinase-II in experimental liver fibrosis in rats
    • Takahara, T., Furui, K., Funaki, J. et al. (1995) Increased expression of matrix metalloproteinase-II in experimental liver fibrosis in rats. Hepatology 21, 787-795
    • (1995) Hepatology , vol.21 , pp. 787-795
    • Takahara, T.1    Furui, K.2    Funaki, J.3
  • 35
    • 0030724689 scopus 로고    scopus 로고
    • Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers
    • Takahara, T., Furui, K., Yata, Y. et al. (1997) Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers. Hepatology 26, 1521-1529
    • (1997) Hepatology , vol.26 , pp. 1521-1529
    • Takahara, T.1    Furui, K.2    Yata, Y.3
  • 36
    • 0031042108 scopus 로고    scopus 로고
    • Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells
    • Carloni, V., Romanelli, R. G., Pinzani, M., Laffi, G. and Gentilini, P. (1997) Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells. Gastroenterology 112, 522-531
    • (1997) Gastroenterology , vol.112 , pp. 522-531
    • Carloni, V.1    Romanelli, R.G.2    Pinzani, M.3    Laffi, G.4    Gentilini, P.5
  • 37
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman, S. L. (2000) Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 275, 2247-2250
    • (2000) J. Biol. Chem. , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 38
    • 0032410557 scopus 로고    scopus 로고
    • Regression of hepatic fibrosis in hepatitis C with long-term interferon treatment
    • Dufour, J. F., DeLellis, R. and Kaplan, M. M. (1998) Regression of hepatic fibrosis in hepatitis C with long-term interferon treatment. Dig. Dis. Sci. 43, 2573-2576
    • (1998) Dig. Dis. Sci. , vol.43 , pp. 2573-2576
    • Dufour, J.F.1    DeLellis, R.2    Kaplan, M.M.3
  • 39
    • 0032905640 scopus 로고    scopus 로고
    • Modeling the impact of interferon α treatment on liver fibrosis progression in chronic hepatitis C: A dynamic view
    • The Multivirc Group
    • Sobesky, R., Mathurin, P., Charlotte, F. et al. (1999) Modeling the impact of interferon α treatment on liver fibrosis progression in chronic hepatitis C: a dynamic view. The Multivirc Group. Gastroenterology 116, 378-386
    • (1999) Gastroenterology , vol.116 , pp. 378-386
    • Sobesky, R.1    Mathurin, P.2    Charlotte, F.3
  • 40
    • 0029055170 scopus 로고
    • Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes
    • Iredale, J. P., Goddard, S., Murphy, G., Benyon, R. C. and Arthur, M. J. P. (1995) Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes. Clin. Sci. 89, 75-81
    • (1995) Clin. Sci. , vol.89 , pp. 75-81
    • Iredale, J.P.1    Goddard, S.2    Murphy, G.3    Benyon, R.C.4    Arthur, M.J.P.5
  • 41
    • 20644465610 scopus 로고    scopus 로고
    • Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation
    • Benyon, R. C., Hovell, C. J., Da Gaca, M., Jones, E. H., Iredale, J. P. and Arthur, M.J.P. (1999) Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation. Hepatology 30, 977-986
    • (1999) Hepatology , vol.30 , pp. 977-986
    • Benyon, R.C.1    Hovell, C.J.2    Da Gaca, M.3    Jones, E.H.4    Iredale, J.P.5    Arthur, M.J.P.6
  • 42
    • 0031011325 scopus 로고    scopus 로고
    • Differential distribution of five members of the matrix metalloproteinase family and one inhibitor (TIMP-1) in human liver and skin
    • Geisler, S., Lichtinghagen, R., Böker, K. H. W. and Veh, R. W. (1997) Differential distribution of five members of the matrix metalloproteinase family and one inhibitor (TIMP-1) in human liver and skin. Cell Tissue Res. 289, 173-183
    • (1997) Cell Tissue Res. , vol.289 , pp. 173-183
    • Geisler, S.1    Lichtinghagen, R.2    Böker, K.H.W.3    Veh, R.W.4
  • 43
    • 0036135242 scopus 로고    scopus 로고
    • Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C
    • Boeker, K. H. W., Haberkorn, C. I., Michels, D. et al. (2002) Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C. Clin. Chim. Acta 316, 71-81
    • (2002) Clin. Chim. Acta , vol.316 , pp. 71-81
    • Boeker, K.H.W.1    Haberkorn, C.I.2    Michels, D.3
  • 44
    • 0033003651 scopus 로고    scopus 로고
    • Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease
    • Murawaki, Y., Yamada, S., Ikuta, Y. et al. (1999) Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease. J. Hepatol. 30, 1090-1098
    • (1999) J. Hepatol. , vol.30 , pp. 1090-1098
    • Murawaki, Y.1    Yamada, S.2    Ikuta, Y.3
  • 45
    • 0031048395 scopus 로고    scopus 로고
    • Circulating matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as serum markers of fibrosis in patients with chronic hepatitis C
    • Kasahara, A., Hayashi, N., Mochizuki, K. et al. (1997) Circulating matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as serum markers of fibrosis in patients with chronic hepatitis C. J. Hepatol. 26, 574-583
    • (1997) J. Hepatol. , vol.26 , pp. 574-583
    • Kasahara, A.1    Hayashi, N.2    Mochizuki, K.3


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