(S)-albuterol increases intracellular free calcium by muscarinic receptor activation and a phospholipase C-dependent mechanism in airway smooth muscle

Molecular Pharmacology

Volumn 53, Issue 3, 1998, Pages 347-354

  Mitra, Sankar ^a   Ugur, Mehmet ^a   Ugur, Ozlem ^a   Goodman, H Maurice ^a   McCullough, John R ^b   Yamaguchi, Hiroshi ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b SUNOVION PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ATROPINE; INOSITOL 1,4,5 TRISPHOSPHATE; MUSCARINIC RECEPTOR; PHOSPHOLIPASE C; SALBUTAMOL;

ANIMAL CELL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; BRONCHUS MUSCLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; COW; ENANTIOMER; NONHUMAN; PRIORITY JOURNAL; RACEMIC MIXTURE; STEREOCHEMISTRY; TRACHEA MUSCLE;

EID: 0031966248     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.53.3.347     Document Type: Article

References (32)

1. Barrett TE and Strom BL (1995) Inhaled beta-adrenergic agonists in asthma: more harm than good? Am J Crit Care Med 151:574-577.
2. Berridge MJ (1993) Inositol trisphosphate and calcium signalling. Nature (Lond) 361:315-325.
3. 2-selective adrenoceptor antagonist (ICI 118, 551). J Cardiovasc Pharmacol 5:430-437.
4. Bleasdale JE, Thakur NR, Gremban RS, Bundy GL, Fitzpatrick FA, Smith RJ, and Bunting S (1990) Selective inhibition of receptor-coupled phospholipase C-dependent process in human platelets and polymorphonuclear neutrophils. J Pharmacol Exp Ther 255:756-768.
5. Bradford MB (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
6. 50) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108.
7. Chilvers ER, Batty IH, Barns PJ, and Nahorski SR (1990) Formation of inositol polyphosphates in airway smooth muscles after muscarinic receptor stimulation. J Pharmacol Exp Ther 252:786-791.
8. Cockcroft DW, McParland CP, Britto SA, Swystun VA, and Rutherford BC (1993) Regular inhaled salbutamol and airway responsiveness to allergen. Lancet 342: 833-837.
9. Eglen RM, Cornett CM, and Whiting RL (1990) Interaction of p-F-HHSiD (p-fluorohexahydrosila-difenidol) at muscarinic receptors in guinea-pig trachea. Naunyn-Schmiedeberg's Arch Pharmacol 342:394-399.
10. Gibson GJ, Greenacre CJ, Konig P, Conolly ME, and Pride NB (1978) Use of exercise challenge to investigate possible tolerance to beta-adrenergic stimulation in asthma. Br J Dis Chest 72:199-206.
11. Grainger JK, Woodman N, Pearce J, Crane C, Burgess C, Keane A, and Bearsley R (1991) Prescribed fenoterol and death from asthma in New Zealand, 1981-1987: a further case-control study. Thorax 46:105-111.
12. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
13. Hamilton SL, Yatani A, Brush K, Schwartz A, and Brown A (1987) A comparison between the binding and electrophysiological effects of dihydropyridins on cardiac membranes. Mol Pharmacol 31:221-231.
14. Johnson M, Butchers PR, Coleman, RA, Nials AT, Strong P, Summer MJ, Vardey CJ, and Wherlan CJ (1993) The pharmacology of salmetenol. Life Sci 52:2131-2143.
15. Kajita J and Yamaguchi H (1993) Calcium mobilization by muscarinic cholinergic stimulation in bovine single airway smooth muscle. Am J Physiol 264:L496-L503.
16. Kerrebijin KF, von Essen-zandvilet EEM, and Neijens HJ (1987) Effect of long-term treatment with inhaled corticosteroid and beta-agonists on bronchial responsiveness in asthmatic children. J Allergy Clin Immunol 79:653-659.
17. 2+ channels in intact cardiac cells: voltage-dependent effects and cooperative interactions of dihydropyridine enantiomers. Mol Pharmacol 30:571-584.
18. Lucchesi PA, Scheid CR, Romano FD, Kargacin ME, Mullikin-Kilpatrick D, Yamaguchi H, and Honeyman TW (1990) Ligand binding and G protein coupling of muscarinic receptors in airway smooth muscle. Am J Physiol 258:C730-C738.
19. Mazzoni L, Naef R, Chapman ID, and Morley J (1994) Hyperresponsiveness of the airways following exposure of guinea-pigs to racemic mixtures and distomers of beta2-selective sympathomimetics. Pulm Pharmacol 7:367-376.
20. 2+ concentration. J Physiol (Lond) 439:147-160.
21. Nishikawa M, Mak J, Shirasaki H, Harding S, and Barns P (1994) Long-term exposure to noradrenaline results in down-regulation and reduced mRNA expression of pulmonary β-adrenergic receptors. Am J Respir Cell Mol Biol 10:91-99.
22. Putney JW Jr (1986) A model for receptor-regulated calcium entry. Cell Calcium 7:1-12.
23. 2+ influx. Nature (Lond) 364:809-813.
24. Sears MR, Taylor DR, Print CG, Lake DC, Li Q, Flannery EM, Yates DM, Lucas MK, and Herbison GP (1990) Regular inhaled beta-agonist treatment in bronchial asthma. Lancet 336:1391-1396.
25. Spitzer WO, Suissa S, Ernst P, Horwitz RI, Habbick B, Cockcroft D, Boivin JF, McNutt M, Buist AS, Rebuck AS (1992) The use of β-agonists and risk of death and near death from asthma. N Engl J Med 326:501-506.
26. Straser RH, Cerion RA, Codina J, Caron MG, and Lefkowitz RJ (1985) Homologous desensitization of the β-adrenergic receptor: functional integrity of the desensitized receptor from mammalian lung. Mol Pharmacol 28:237-245.
27. Suissa S, Ernst P, Boivin JF, Horvitz RI, Cockroft D, Blais L, McNutt M, Buist AS, and Spitzer WO (1994) A cohort analysis of excess mortality in asthma and the use of inhaled β-agonists. Am J Respir Crit Care Med 149:604-610.
28. Taylor DR, Sears MR, Herbison GP, Print CG, Lake DC, Yates DM, Lucas MK, and Li Q (1993) Regular inhaled β-agonist in asthma: effects on exacerbations and lung function. Thorax 48:134-138.
29. 2-agonist treatment. Am Rev Respir Dis 148:707-712.
30. 2+] in single airway smooth muscle cells. Am J Physiol 268:C771-C779.
31. Yamaguchi H and McCullough JR (1996) (S)-Albuterol exacerbates calcium responses to carbachol in airway smooth muscle cells. Clin Rev Allergy Immunol 14:47-55.
32. 3 muscarinic receptors. Br J Pharmacol 110:983-988.