Involvement of DNase γ in apoptotic DNA fragmentation in histiocytic necrotizing lymphadenitis

Virchows Archiv

Volumn 443, Issue 2, 2003, Pages 170-174

  Higami, Yoshikazu ^a   To, Kazuo ^a   Ohtani, Hiroshi ^a   Masui, Kenta ^a   Iwasaki, Keisuke ^b   Shiokawa, Daisuke ^c   Tanuma, Sei Ichi ^c   Shimokawa, Isao ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b Sasebo Shiritsu Sogo Hospital   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Apoptosis; DNase ; Histiocytic necrotizing lymphadenitis; Immunohistochemistry; Terminal deoxynucleotidyl transferase mediated deoxyuridine triphosphate mediated dUTP nick end labeling

Indexed keywords

DEOXYRIBONUCLEASE; DEOXYRIBONUCLEASE GAMMA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; DNA DEGRADATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIKUCHI DISEASE; MALE; NICK END LABELING; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; DNA FRAGMENTATION; ENDODEOXYRIBONUCLEASES; FEMALE; GERMINAL CENTER; HISTIOCYTIC NECROTIZING LYMPHADENITIS; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU NICK-END LABELING; LYMPH NODES; MALE; MIDDLE AGED;

EID: 0042855296     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-003-0822-2     Document Type: Article

References (21)

1. Alessenko AV, Boikov PV, Filippova GN, Khrenov AV, Loginov AS, Makarieva ED (1997) Mechanisms of cycloheximide-induced apoptosis in liver cells. FEBS Lett 416:113-116
2. Arends MJ, Morris RG, Wyllie AH (1990) Apoptosis. The role of the endonuclease. Am J Pathol 136:593-608
3. Cotran RS, Kumar V, Collins T (1999) Cellular pathology I. Cell injury and cell death. In: Cotran RS, Kumar V, Collins T (eds) Robbins pathologic basis of disease, 6th edn. Saunders, Philadelphia, pp 1-29
4. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391:43-50
5. Felgar RE, Furth EE, Wasik MA, Gluckman SJ, Salhany KE (1997) Histiocytic necrotizing lymphadenitis (Kikuchi's disease): in situ end-labeling, immunohistochemical, and serologic evidence supporting cytotoxic lymphocyte-mediated apoptotic cell death. Mod Pathol 10:231-241
6. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501
7. Higami Y, Tanaka K, Tsuchiya T, Shimokawa I (2000) Intravenous injection of cycloheximide induces apoptosis and up-regulates p53 and Fas receptor expression in the rat liver in vivo. Mutat Res 457:105-111
8. Kikuchi M (1972) Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes: a clinico-pathological study (in Japanese). Acta Hematol Jpn 35:379-380
9. Liu Q, Ohshima K, Shinohara T, Kikuchi M (1995) Apoptosis in histiocytic necrotizing lymphadenitis. Pathol Int 45:729-734
10. Mukae N, Enari M, Sakahira H, Fukuda Y, Inazawa J, Toh H, Nagata S (1998) Molecular cloning and characterization of human caspase-activated DNase. Proc Natl Acad Sci U S A 95:9123-9128
11. Ohshima K, Kikuchi M, Sumiyoshi Y, Masuda Y, Mohtai H, Eguchi F, Takeshita M (1991) Proliferating cells in histiocytic necrotizing lymphadenitis. Virchows Arch B Cell Pathol 61:97-100
12. Ohshima K, Shimazaki K, Kume T, Suzumiya J, Kanda M, Kikuchi M (1998) Perforin and Fas pathways of cytotoxic T-cells in histiocytic necrotizing lymphadenitis. Histopathology 33:471-478
13. Ohshima K, Shimazaki K, Suzumiya J, Kanda M, Kumagawa M, Kikuchi M (1998) Apoptosis of cytotoxic T-cells in histiocytic necrotizing lymphadenitis. Virchows Arch 433:131-134
14. Peitsch MC, Polzar B, Stephan H, Crompton T, MacDonald HR, Mannherz HG, Tschopp J (1993) Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO J 12:371-377
15. Shiokawa D, Tanuma S (1998) Molecular cloning and expression of a cDNA encoding an apoptotic endonuclease DNase gamma. Biochem J 332:713-720
16. Shiokawa D, Iwamatsu A, Tanuma S (1997) Purification, characterization, and amino acid sequencing of DNase gamma from rat spleen. Arch Biochem Biophys 346:15-20
17. Shiokawa D, Tanaka M, Kimura T, Hashizume K, Takasawa R, Ohyama H, Fujita K, Yamada T, Tanuma S (2000) Characterization of two DNase gamma-specific monoclonal antibodies and the in situ detection of DNase gamma in the nuclei of apoptotic rat thymocytes. Biochem Biophys Res Commun 275:343-349
18. Takakuwa T, Ohnuma S, Koike J, Hoshikawa M, Koizumi H (1996) Involvement of cell-mediated killing in apoptosis in histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease). Histopathology 28:41-48
19. Tanuma S, Shiokawa D (1994) Multiple forms of nuclear deoxyribonuclease in rat thymocytes. Biochem Biophys Res Commun 203:789-797
20. Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556
21. Zhao QL, Kondo T, Noda A, Fujiwara Y (1999) Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells. Int J Radiat Biol 75:493-504