Hypoxia reduces CD80 expression on monocytes but enhances their LPS-stimulated TNF-α secretion

Journal of Leukocyte Biology

Volumn 74, Issue 2, 2003, Pages 197-205

  Lahat, Nitza ^a   Rahat, Michal A ^a   Ballan, Mouna ^a   Weiss Cerem, Lea ^a   Engelmayer, Miri ^a   Bitterman, Haim ^a  

^a CARMEL MEDICAL CENTER   (Israel)

Author keywords

CD86; HLA DR; Reoxygenation

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; HLA DR ANTIGEN; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; CD86 PROTEIN, HUMAN; CD86 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; OXYGEN; PRIMER DNA;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL TRANSLOCATION; CELL LINE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; ISCHEMIA; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REOXYGENATION; REPERFUSION INJURY; RNA SPLICING; SUPERNATANT; SURFACE PROPERTY; ALTERNATIVE RNA SPLICING; ANIMAL; ANOXIA; BAGG ALBINO MOUSE; CHEMISTRY; GENETICS; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION; WESTERN BLOTTING;

ANIMALIA; BACTERIA (MICROORGANISMS);

ALTERNATIVE SPLICING; ANIMALS; ANOXIA; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, CD86; BLOTTING, WESTERN; DNA PRIMERS; DOWN-REGULATION; FEMALE; HLA-DR ANTIGENS; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MONOCYTES; OXYGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0042852121     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0303105     Document Type: Article

References (48)

1. Patel, A., Kaleya, R. N., Sammartano, R. J. (1992) Pathophysiology of mesenteric ischemia. Surg. Clin. North Am. 72, 31-41.
2. Granger, D. N., Korthius, R. J. (1995) Physiologic mechanisms of post-ischemic tissue injury. Annu. Rev. Physiol. 57, 311-332.
3. Lefer, A. M. (1983) Lysosomes in pathogenesis of circulatory shock. In Handbook of Shock and Trauma (B. M. Altura, ed.), New York, NY, Raven, 291-304.
4. Levine, L. (1993) Ischemia: from acidosis to oxidation. FASEB J. 7, 1242-1246.
5. Mitsudo, S., Brandy, L. J. (1992) Pathology of intestinal ischemia. Surg. Clin. North Am. 72, 43-63.
6. Bitterman, H., Aoki, N., Lefer, A. M. (1988) Anti-shock effects of human superoxide dismmutase in splanchnic artery occlusion shock. Proc. Soc. Exp. Biol. Med. 188, 265-271.
7. Grotz, M. R. W., Ding, J., Guo, W., Huang, Q., Deitch, E. A. (1995) Comparison of plasma cytokine levels in rats subjected to superior mesenteric artery occlusion or hemorrhagic shock. Shock 3, 362-368.
8. Lemaire, L. C., van-Wagensveld, B. A., van-Gulik, T. M., Dankert, J., van-Lanschot, J. J., Gouma, D. J. (1999) Bacterial translocation to the thoracic duct in a setting of ischemia, partial resection and reperfusion of the porcine liver. Dig. Surg. 16, 222-228.
9. Deitch, E. A. (1990) Gut failure: its role in the multiple organ failure syndrome. In Multiple Organ Failure-Pathophysiology and Basic Concept of Therapy (E. A. Deitch, ed.), New York, NY, Thiene Medical, 40-59.
10. Tjardes, T., Neugebauer, E. (2002) Sepsis research in the next millennium: concentrate on the software rather than the hardware. Shock 17, 1-8.
11. Takala, A., Nupponen, I., Kylanpaa-Back, M. L., Repo, H. (2002) Markers of inflammation in sepsis. Ann. Med. 34, 614-623.
12. Oberholzer, C., Oberholzer, A., Clare-Salzer, M., Moldawer, L. L. (2001) Apoptosis in sepsis: a new target for therapeutic exploration. FASEB J. 15, 879-892.
13. Zimmerman, B. J., Granger, D. N. (1992) Reperfusion injury. Surg. Clin. North Am. 72, 65-83.
14. Lefer, A. M., Lefer, D. J. (1993) Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock. Annu. Rev. Pharmacol. Toxicol. 33, 71-90.
15. Tiano, G., Rafferty, J., Ogle, C., Fusher, J. E., Hasselgren, P. O. (1994) Detrimental effect of nitric oxide synthase inhibition during endotoxiamia may be caused by high levels of tumor necrosis factor α and interleukin 6. Surgery 116, 332-338.
16. Bitterman, H., Kinarty, A., Lazarovich, H., Lahat, N. (1991) Acute release of cytokines is proportional to tissue injury induced by surgical trauma and shock. J. Clin. Immunol. 11, 184-192.
17. Cohen, S., Lahat, N., Kinarty, A., Bitterman, H. (1992) Ex vivo secretion of tumor necrosis factor and interleukin-2 by rat splenocytes after intestinal ischemia and shock. Lymphokine Cytokine Res. 11, 215-220.
18. Van Gool, S. W., Vandenberghe, P., deBoer, M., Ceuppens, J. L. (1996) CD80, CD86 and CD40 provide accessory signals in a multiple-step T-cell activation model. Immunol. Rev. 153, 47-83.
19. Kuchroo, V. K., Das, M. P., Brown, J. A., Ranger, A. M., Zamvil, S. S., Sobel, R. A., Weiner, H. L., Nabavi, N., Glimcher, L. H. (1995) B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80, 707-718.
20. Harris, N. L., Prout, M., Peach, R. J., Fazekas de St. Groth, B., Ronchese, F. (2001) CD80 costimulation is required for Th2 cell cytokine production but not for antigen-specific accumulation and migration into the lung. J. Immunol. 166, 4908-4914.
21. Anderson, D. E., Sharpe, A. H., Hafler, D. A. (1999) The B7-CD28/CTLA-4 costimulatory pathways in autoimmune disease of the central nervous system. Curr. Opin. Immunol. 11, 677-683.
22. Lu, P., Wang, Y. L., Linsley, P. S. (1997) Regulation of self-tolerance by CD80/CD86 interactions. Curr. Opin. Immunol. 9, 858-862.
23. Redmond, H. P., Hofmann, K., Shou, J., Leon, P., Kelly, C. J., Daly, J. M. (1992) Effects of laparotomy on systemic macrophage function. Surgery 111, 647-655.
24. Ayala, A., Perrin, M. M., Chaudry, I. H. (1990) Defective macrophage antigen presentation following hemorrhage is associated with the loss of MHC class II (Ia) antigens. Immunology 70, 33-39.
25. Ayala, A., Perrin, M. M., Ertel, W., Chaudry, I. H. (1992) Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNFα) release. Cytokine 4, 66-75.
26. Polk, H. C., George, C. D., Wellhausen, S. R. (1986) A systemic study of the host defense in badly injured patients. Ann. Surg. 204, 282-299.
27. Ayala, A., Ertel, W., Chaudry, I. H. (1996) Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes. Shock 5, 79-90.
28. Beutler, B., Cerami, A. (1988) Tumor necrosis, cachexia, shock and inflammation: a common mediator. Annu. Rev. Biochem. 57, 505-518.
29. Song, G. Y., Chung, C. S., Chaudry, I. H., Ayala, A. (2000) Immune suppression in polymicrobial sepsis: differential regulation of Th1 and Th2 responses by p38 MAPK. J. Surg. Res. 91, 141-146.
30. Song, G. Y., Chung, C. S., Chaudry, I., Ayala, A. (2000) IL-4-induced activation of the Stat6 pathway contribute to the suppression of cell-mediated immunity and death in sepsis. Surgery 128, 133-138.
31. Lin, R. Y., Saha, D. C., Bernstein, C. J., Astiz, M. E., Rackow, E. C. (1996) The pattern of inflammation in rat sepsis due to enterotoxin-producing staphylococcus aureus: a comparison with ischemia-reperfusion injury. J. Med. 25, 303-317.
32. Takada, M., Chandrakerm, A., Nadeaum, K. C., Sayeghm, M. H., Tilneym, N. L. (1997) The role of the B7 co-stimulatory pathway in experimental cold ischemia/reperfusion injury. J. Clin. Invest. 100, 1199-1203.
33. Scannell, G., Waxman, K., Kaml, G. J., Ioli, G., Gatanaga, T., Yamamoto, R., Granger, G. A. (1993) Hypoxia induces a human macrophage cell line to release tumor necrosis factor -α and its soluble receptors in vitro. J. Surg. Res. 54, 281-285.
34. Guida, E., Stewart, A. (1998) Influence of hypoxia and glucose deprivation on tumor necrosis factor alpha and granulocyte-macrophage colony stimulating factor expression in human cultured monocytes. Cell. Physiol. Biochem. 8, 75-88.
35. VanOtten, G. N., Standiford, T. J., Kunkel, S. L., Danforth, J. M., Strieter, R. M. (1995) Alterations of ambient oxygen Alterations of ambient oxygen tension modulate the expression of tumor necrosis factor and macrophage inflammatory, protein-1 α from murine alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 13, 399-409.
36. Meager, A., Leung, H., Wolly, J. (1989) Assays for tumor necrosis factor and kind related cytokines. J. Immunol. Methods 116, 1-17.
37. Han, J., Brown, T., Beutler, B. (1990) Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the transcriptional level. J. Exp. Med. 171, 465-475.
38. Han, J., Huez, G., Beutler, B. (1991) Interactive effects of the tumor necrosis factor promoter and 3′-untranslated regions. J. Immunol. 146, 1843-1848.
39. Leeper-Woodford, S. K., Detmer, K. (1999) Acute hypoxia increases alveolar macrophage tumor necrosis factor activity and alters NF-κB expression. Am. J. Physiol. 276, L909-L916.
40. Lederer, J. A., Rodrick, M. L., Mannick, J. A. (1999) The effects of injury on the adaptive immune response. Shock 11, 153-159.
41. Rosengart, M. R., Arbabi, S., Garcia, I., Maier, R. V. (2000) Interactions of calcium/calmodulin-dependent kinase (CaMK) and extracellular-regulated kinase (ERK) in monocyte adherence and TNFα production. Shock, 13, 183-189.
42. Kolber, M. A., Saenz, M. O. (2001) Enhancement of antigen driven lymphocyte proliferation secondary to GP41-induced B7 expression on adherent monocytes. Cell. Immunol. 214, 35-44.
43. DeGreef, K. E., Ysebaert, D. K., Dauwe, S., Persy, V., Vercauteren, S. R., Mey, D., DeBroe, M. E. (2001) Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia. Kidney Int. 60, 1415-1427.
44. Manna, P. P., Duffy, B., Olack, B., Lowell, J., Mohanakumar, T. (2001) Activation of human dendritic cells by poreine aortic endothelial cells: transactivation of naive T cells through costimulation and cytokine generation. Transplantation 72, 1563-1571.
45. McHugh, R. S., Rantoff, W. D., Gilmartin, R., Sell, K. W., Selvaraj, P. (1998) Detection of a soluble form of B7-1 (CD80) in synovial fluid from patients with arthritis using monoclonal antibodies against district epitopes of human B7-1. Clin. Immunol Immunopathol. 87, 50-59.
46. Faas, S. J., Giannoni, M. A., Mickle, A. P., Kiesecker, C. L., Reed, D. J., Wu, D., Fodor, W. L., Mueller, J. P., Matis, L. A., Rother, R. P. (2000) Primary structure and functional characterization of a soluble, alternatively spliced form of B7-1. J. Immunol. 164, 6340-6348.
47. Gamble, J. R., Skimmer, M. P., Berndt, M. C., Vadas, M. A. (1990) Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP-140. Science 249, 414-417.
48. McDermott, M. F., Aksentijevich, I., Galon, J. Nedermott, E. M., Ognukolade, B. W. Centola, M., Mansfield, E., Gadina, M., Karenko, L., Petterson, T., McCarthy, J., Frucht, D. M., Aringer, M., Torosyan, Y., Teppo, A. M., Wilson, M., Karaarslan, H. M., Wan, Y., Todd, I., Wood, G., Schlimgen, R., Kumarajeewa, T. R., Cooper, S. M., Vella, J. P., Kastner, D. L., et al. (1999) Germline mutations in the extracellulare domain of the 55 kDA TNF receptor, TNFRI, define a family of dominantly inherited autoinflammatory syndromes. Cell 97, 133-144.