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Volumn 163, Issue 2, 2003, Pages 465-476

Tumor necrosis factor-α acts as a complete mitogen for primary rat hepatocytes

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DIMETHYL SULFOXIDE; DNA; EPIDERMAL GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGENIC AGENT; PROTEIN P50; SYNAPTOTAGMIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0042847072     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63676-0     Document Type: Article
Times cited : (19)

References (59)
  • 1
    • 0030990177 scopus 로고    scopus 로고
    • Bile ducts and portal and central veins are major producers of tumor necrosis factor α in regenerating liver
    • Loffreda S, Rai R, Yang SQ, Lin HZ, Diehl AM: Bile ducts and portal and central veins are major producers of tumor necrosis factor α in regenerating liver. Gastroenterology 1997, 112:2089-2098
    • (1997) Gastroenterology , vol.112 , pp. 2089-2098
    • Loffreda, S.1    Rai, R.2    Yang, S.Q.3    Lin, H.Z.4    Diehl, A.M.5
  • 3
    • 0031787394 scopus 로고    scopus 로고
    • Tumor necrosis factor primes hepatocytes for DNA replication in the rat
    • Webber EM, Bruix J, Pierce RH, Fausto N: Tumor necrosis factor primes hepatocytes for DNA replication in the rat. Hepatology 1998, 28:1226-1234
    • (1998) Hepatology , vol.28 , pp. 1226-1234
    • Webber, E.M.1    Bruix, J.2    Pierce, R.H.3    Fausto, N.4
  • 4
    • 0031028140 scopus 로고    scopus 로고
    • Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
    • Yamada Y, Kirillova I, Peschon JJ, Fausto N: Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc Natl Acad Sci USA 1997, 94:1141-1146
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1141-1146
    • Yamada, Y.1    Kirillova, I.2    Peschon, J.J.3    Fausto, N.4
  • 5
    • 0042994138 scopus 로고    scopus 로고
    • Analysis of liver regeneration in mice lacking type I or type II TNF receptor: Requirement for type I but not type II receptor
    • Yamada Y, Webber EM, Kirillova I, Peschon JJ, Fausto N: Analysis of liver regeneration in mice lacking type I or type II TNF receptor: requirement for type I but not type II receptor. Hepatology 1998, 28:906-913
    • (1998) Hepatology , vol.28 , pp. 906-913
    • Yamada, Y.1    Webber, E.M.2    Kirillova, I.3    Peschon, J.J.4    Fausto, N.5
  • 7
    • 0029997619 scopus 로고    scopus 로고
    • Activation of the tumor necrosis factor-alpha system in the liver in chronic hepatitis B virus infection
    • Fang JW, Shen WW, Meager A, Lau JY: Activation of the tumor necrosis factor-alpha system in the liver in chronic hepatitis B virus infection. Am J Gastroenterol 1996, 91:748-753
    • (1996) Am J Gastroenterol , vol.91 , pp. 748-753
    • Fang, J.W.1    Shen, W.W.2    Meager, A.3    Lau, J.Y.4
  • 9
    • 0026026639 scopus 로고
    • Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients
    • Khoruts A, Stahnke L, McClain CJ, Logan G, Allen JI: Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients. Hepatology 1991, 13:267-276
    • (1991) Hepatology , vol.13 , pp. 267-276
    • Khoruts, A.1    Stahnke, L.2    McClain, C.J.3    Logan, G.4    Allen, J.I.5
  • 10
    • 0034733682 scopus 로고    scopus 로고
    • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
    • Chan FK-M, Chun HJ, Zheng L, Siegel RM, Bui KL, Lenardo MJ: A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 2000, 288:2351-2353
    • (2000) Science , vol.288 , pp. 2351-2353
    • Chan, F.K.-M.1    Chun, H.J.2    Zheng, L.3    Siegel, R.M.4    Bui, K.L.5    Lenardo, M.J.6
  • 12
    • 0028353492 scopus 로고
    • The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation and death
    • Smith CA, Farrah T, Goodwin RA: The TNF receptor superfamily of cellular and viral proteins: activation, costimulation and death. Cell 1994, 76:959-962
    • (1994) Cell , vol.76 , pp. 959-962
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.A.3
  • 13
    • 0027211704 scopus 로고
    • Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
    • Banner DW, D'Arcy A, Janes W, Gentz R, Schoenfeld HJ, Broger C, Loetscher H, Lesslauer W: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell 1993, 73:431-445
    • (1993) Cell , vol.73 , pp. 431-445
    • Banner, D.W.1    D'Arcy, A.2    Janes, W.3    Gentz, R.4    Schoenfeld, H.J.5    Broger, C.6    Loetscher, H.7    Lesslauer, W.8
  • 15
  • 17
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
    • Rothe M, Wong SC, Henzel WJ, Goeddel DV: A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 1994, 78:681-692
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 18
    • 0030447483 scopus 로고    scopus 로고
    • The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
    • Shu H-B, Takeuchi M, Goeddel DV: The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc Natl Acad Sci USA 1996, 93:13973-13978
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13973-13978
    • Shu, H.-B.1    Takeuchi, M.2    Goeddel, D.V.3
  • 20
    • 0028040336 scopus 로고
    • In vivo response of hepatocytes to growth factors requires an initial priming stimulus
    • Webber EM, Godowski PJ, Fausto N: In vivo response of hepatocytes to growth factors requires an initial priming stimulus. Hepatology 1994, 14:489-497
    • (1994) Hepatology , vol.14 , pp. 489-497
    • Webber, E.M.1    Godowski, P.J.2    Fausto, N.3
  • 21
    • 0024394709 scopus 로고
    • Transforming growth factor α stimulates proto-oncogene c-jun expression and a mitogenic program in primary cultures of adult rat hepatocytes
    • Brenner DA, Koch KS, Leffert HL: Transforming growth factor α stimulates proto-oncogene c-jun expression and a mitogenic program in primary cultures of adult rat hepatocytes. DNA 1989, 8:279-285
    • (1989) DNA , vol.8 , pp. 279-285
    • Brenner, D.A.1    Koch, K.S.2    Leffert, H.L.3
  • 22
    • 0041531109 scopus 로고
    • Transforming growth factor α may be a physio-logical regulator of liver regeneration by means of an autocrine mechanism
    • Mead JE, Fausto N: Transforming growth factor α may be a physio-logical regulator of liver regeneration by means of an autocrine mechanism. Proc Natl Acad Sci USA 1989, 86:1559-1562
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1559-1562
    • Mead, J.E.1    Fausto, N.2
  • 23
    • 0344913663 scopus 로고
    • Heparin-binding growth factor type I (acidic fibroblast growth factor): A potential biphasic autocrine and paracrine regulator of hepatocyte regeneration
    • Kan M, Huang J, Mansson P-EYH, Carr B, McKeehan WL: Heparin-binding growth factor type I (acidic fibroblast growth factor): a potential biphasic autocrine and paracrine regulator of hepatocyte regeneration. Proc Natl Acad Sci USA 1989, 86:7432-7436
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7432-7436
    • Kan, M.1    Huang, J.2    Mansson, P.-E.Y.H.3    Carr, B.4    McKeehan, W.L.5
  • 24
    • 0025309633 scopus 로고
    • Acidic fibroblast growth factor (HBGF-1) stimulates DNA synthesis in primary rat hepatocyte cultures
    • Houck KA, Zamegar R, Muga SJ, Michalopoulos GK: Acidic fibroblast growth factor (HBGF-1) stimulates DNA synthesis in primary rat hepatocyte cultures. J Cell Physiol 1990, 143:129-132
    • (1990) J Cell Physiol , vol.143 , pp. 129-132
    • Houck, K.A.1    Zamegar, R.2    Muga, S.J.3    Michalopoulos, G.K.4
  • 25
    • 0025051896 scopus 로고
    • Basic fibroblast growth factor and transforming growth factor-alpha are hepatotrophic mitogens in vitro
    • Hoffmann B, Paul D: Basic fibroblast growth factor and transforming growth factor-alpha are hepatotrophic mitogens in vitro J Cell Physiol 1990, 142:149-154
    • (1990) J Cell Physiol , vol.142 , pp. 149-154
    • Hoffmann, B.1    Paul, D.2
  • 26
    • 0342626828 scopus 로고
    • Hormonal stimulation of DNA synthesis in primary cultures of adult rat hepatocytes
    • Richman RA, Claus TH, Pilkis SJ, Friedman DL: Hormonal stimulation of DNA synthesis in primary cultures of adult rat hepatocytes. Proc Natl Acad Sci USA 1976, 73:3589-3593
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 3589-3593
    • Richman, R.A.1    Claus, T.H.2    Pilkis, S.J.3    Friedman, D.L.4
  • 27
    • 0019458617 scopus 로고
    • DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: Effects of epidermal growth factor, insulin, glucagon, and cyclic-AMP
    • McGowan JA, Strain AJ, Bucher NLR: DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: effects of epidermal growth factor, insulin, glucagon, and cyclic-AMP. J Cell Physiol 1981, 108:353-363
    • (1981) J Cell Physiol , vol.108 , pp. 353-363
    • McGowan, J.A.1    Strain, A.J.2    Bucher, N.L.R.3
  • 29
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura T, Nawa K, Ichihara A: Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 1984, 122:1450-1459
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 31
    • 0029159792 scopus 로고
    • Cell-specific expression of transforming growth factor-α in rat liver
    • Bissell DM, Wang S-S, Jarnagin WR, Roll FJ: Cell-specific expression of transforming growth factor-α in rat liver. J Clin Invest 1995, 96:447-455
    • (1995) J Clin Invest , vol.96 , pp. 447-455
    • Bissell, D.M.1    Wang, S.-S.2    Jarnagin, W.R.3    Roll, F.J.4
  • 32
    • 0023949975 scopus 로고
    • Transforming growth factor beta (TGF-α) inhibits hepatocyte DNA synthesis independently of EGF binding and EGF receptor autophosphorylation
    • Russell WE: Transforming growth factor beta (TGF-α) inhibits hepatocyte DNA synthesis independently of EGF binding and EGF receptor autophosphorylation. J Cell Physiol 1988, 135:253-261
    • (1988) J Cell Physiol , vol.135 , pp. 253-261
    • Russell, W.E.1
  • 33
    • 0022966647 scopus 로고
    • Divergent action of transforming growth factor β on DNA synthesis in human foetal liver cells
    • Strain AJ, Hill DJ, Milner RDG: Divergent action of transforming growth factor β on DNA synthesis in human foetal liver cells. Cell Biol Int Rep 1986, 10:855-860
    • (1986) Cell Biol Int Rep , vol.10 , pp. 855-860
    • Strain, A.J.1    Hill, D.J.2    Milner, R.D.G.3
  • 34
    • 0022297755 scopus 로고
    • Inhibitory effect of transforming growth factor β on DNA synthesis of adult rat hepatocytes in primary culture
    • Nakamura T, Tomita Y, Hirai R, Yamaoka K, Kaji K, Ichihara A: Inhibitory effect of transforming growth factor β on DNA synthesis of adult rat hepatocytes in primary culture. Biochem Biophys Res Commun 1985, 133:1042-1050
    • (1985) Biochem Biophys Res Commun , vol.133 , pp. 1042-1050
    • Nakamura, T.1    Tomita, Y.2    Hirai, R.3    Yamaoka, K.4    Kaji, K.5    Ichihara, A.6
  • 35
    • 0027394290 scopus 로고
    • Stimulation of DNA synthesis and protooncogene expression in primary rat hepatocytes in long-term DMSO culture
    • Serra R, Isom HC: Stimulation of DNA synthesis and protooncogene expression in primary rat hepatocytes in long-term DMSO culture. J Cell Physiol 1993, 154:543-553
    • (1993) J Cell Physiol , vol.154 , pp. 543-553
    • Serra, R.1    Isom, H.C.2
  • 36
    • 0022569829 scopus 로고
    • Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor
    • Carr BI, Hayashi I, Branum EL, Moses HL: Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor. Cancer Res 1986, 46:2330-2334
    • (1986) Cancer Res , vol.46 , pp. 2330-2334
    • Carr, B.I.1    Hayashi, I.2    Branum, E.L.3    Moses, H.L.4
  • 37
    • 0025224239 scopus 로고
    • The growth factor-like effects of tumor necrosis factor-α
    • Cornelius P, Marlowe M, Lee MD, Pekala PH: The growth factor-like effects of tumor necrosis factor-α. J Biol Chem 1990, 265:20506-20516
    • (1990) J Biol Chem , vol.265 , pp. 20506-20516
    • Cornelius, P.1    Marlowe, M.2    Lee, M.D.3    Pekala, P.H.4
  • 38
  • 39
    • 0022382737 scopus 로고
    • Recombinant human tumor necrosis factor-α: Effects on proliferation of normal and transformed cells in vitro
    • Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino MA, Shepard HM: Recombinant human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro. Science 1985, 230:943-945
    • (1985) Science , vol.230 , pp. 943-945
    • Sugarman, B.J.1    Aggarwal, B.B.2    Hass, P.E.3    Figari, I.S.4    Palladino, M.A.5    Shepard, H.M.6
  • 40
    • 0025059309 scopus 로고
    • Induction of replicative competence ("priming") in normal liver
    • Mead JE, Braun L, Martin DA, Fausto N: Induction of replicative competence ("priming") in normal liver. Cancer Res 1990, 50:7023-7030
    • (1990) Cancer Res , vol.50 , pp. 7023-7030
    • Mead, J.E.1    Braun, L.2    Martin, D.A.3    Fausto, N.4
  • 41
    • 0028238890 scopus 로고
    • Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor-α in adult rat liver
    • Liu M-L, Mars WM, Zarnegar R, Michalopoulos GK: Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor-α in adult rat liver. Hepatology 1994, 19:1521-1527
    • (1994) Hepatology , vol.19 , pp. 1521-1527
    • Liu, M.-L.1    Mars, W.M.2    Zarnegar, R.3    Michalopoulos, G.K.4
  • 42
    • 0014854634 scopus 로고
    • Accelerated response of hepatic DNA synthesis to partial hepatectomy in rats pretreated with growth hormone or surgical stress
    • Moolten FL, Oakman NJ, Bucher NL: Accelerated response of hepatic DNA synthesis to partial hepatectomy in rats pretreated with growth hormone or surgical stress. Cancer Res 1970, 30:2353-2357
    • (1970) Cancer Res , vol.30 , pp. 2353-2357
    • Moolten, F.L.1    Oakman, N.J.2    Bucher, N.L.3
  • 43
    • 0023574001 scopus 로고
    • Persistence of liver-specific messenger RNA in cultured hepatocytes: Different regulatory events for different genes
    • Isom H, Georgoff I, Salditt-Georgieff M, Darnell JE: Persistence of liver-specific messenger RNA in cultured hepatocytes: different regulatory events for different genes. J Cell Biol 1987, 105:2877-2885
    • (1987) J Cell Biol , vol.105 , pp. 2877-2885
    • Isom, H.1    Georgoff, I.2    Salditt-Georgieff, M.3    Darnell, J.E.4
  • 45
    • 0038780733 scopus 로고    scopus 로고
    • Role of paracellular junction complexes in baculovirus-mediated gene transfer to non-dividing rat hepatocytes
    • Bilello JP, Cable EE, Myers RL, Isom HC: Role of paracellular junction complexes in baculovirus-mediated gene transfer to non-dividing rat hepatocytes. Gene Ther 2003, 10:733-749
    • (2003) Gene Ther , vol.10 , pp. 733-749
    • Bilello, J.P.1    Cable, E.E.2    Myers, R.L.3    Isom, H.C.4
  • 46
    • 0037378611 scopus 로고    scopus 로고
    • Expression of E-cadherin and other paracellular junction genes is decreased in iron-loaded hepatocytes
    • Bilello JP, Cable EE, Isom HC: Expression of E-cadherin and other paracellular junction genes is decreased in iron-loaded hepatocytes. Am J Pathol 2003, 162:1323-1338
    • (2003) Am J Pathol , vol.162 , pp. 1323-1338
    • Bilello, J.P.1    Cable, E.E.2    Isom, H.C.3
  • 47
    • 0031911846 scopus 로고    scopus 로고
    • Accumulation of iron by primary rat hepatocytes in long term culture
    • Cable EE, Connor JR, Isom HC: Accumulation of iron by primary rat hepatocytes in long term culture. Am J Pathol 1998, 152:781-792
    • (1998) Am J Pathol , vol.152 , pp. 781-792
    • Cable, E.E.1    Connor, J.R.2    Isom, H.C.3
  • 48
    • 0034671766 scopus 로고    scopus 로고
    • Regulation of heme metabolism in rat hepatocytes and hepatocyte cell lines: δ-aminolevulinic acid synthase and heme oxygenase are regulated by different heme-dependent mechanisms
    • Cable EE, Miller TG, Isom HC: Regulation of heme metabolism in rat hepatocytes and hepatocyte cell lines: δ-aminolevulinic acid synthase and heme oxygenase are regulated by different heme-dependent mechanisms. Arch Biochem Biophys 2000, 384:280-295
    • (2000) Arch Biochem Biophys , vol.384 , pp. 280-295
    • Cable, E.E.1    Miller, T.G.2    Isom, H.C.3
  • 49
    • 0026688162 scopus 로고
    • Apoptotic cell death induced by c-myc is inhibited by bcl-2
    • Bissonnette RP, Echeverri F, Mahboubl A, Green DR: Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992, 359:552-554
    • (1992) Nature , vol.359 , pp. 552-554
    • Bissonnette, R.P.1    Echeverri, F.2    Mahboubl, A.3    Green, D.R.4
  • 50
    • 0021346318 scopus 로고
    • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
    • Wyllie AH, Morris RG, Smith AL, Dunlop D: Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 1984, 142:67-77
    • (1984) J Pathol , vol.142 , pp. 67-77
    • Wyllie, A.H.1    Morris, R.G.2    Smith, A.L.3    Dunlop, D.4
  • 52
    • 0030019970 scopus 로고    scopus 로고
    • Tumor necrosis factor-α-induced apoptosis in hepatocytes in long-term culture
    • Bour ES, Ward LK, Cornman GA, Isom HC: Tumor necrosis factor-α-induced apoptosis in hepatocytes in long-term culture. Am J Pathol 1996, 148:485-495
    • (1996) Am J Pathol , vol.148 , pp. 485-495
    • Bour, E.S.1    Ward, L.K.2    Cornman, G.A.3    Isom, H.C.4
  • 53
    • 0028134964 scopus 로고
    • Isolation of nuclear extracts from fragile cells: A simplified procedure applied to thymocytes
    • Olnes MI, Kurl RN: Isolation of nuclear extracts from fragile cells: a simplified procedure applied to thymocytes. Biotechniques 1994, 17:828-829
    • (1994) Biotechniques , vol.17 , pp. 828-829
    • Olnes, M.I.1    Kurl, R.N.2
  • 54
    • 0033961219 scopus 로고    scopus 로고
    • NFκB determines between apoptosis and proliferation in hepatocytes during liver regeneration
    • Plumpe J, Malek NP, Bock CT, Rakemann T, Manns MP, Trautwein C: NFκB determines between apoptosis and proliferation in hepatocytes during liver regeneration. Am J Physiol 2000, 278:G173-G183
    • (2000) Am J Physiol , vol.278
    • Plumpe, J.1    Malek, N.P.2    Bock, C.T.3    Rakemann, T.4    Manns, M.P.5    Trautwein, C.6
  • 55
    • 0022517789 scopus 로고
    • Transformation of rat hepatocytes by transfection of simian virus 40 DNA to yield proliferating cells
    • Woodworth C, Secott T, Isom HC: Transformation of rat hepatocytes by transfection of simian virus 40 DNA to yield proliferating cells. Cancer Res 1986, 46:4018-4026
    • (1986) Cancer Res , vol.46 , pp. 4018-4026
    • Woodworth, C.1    Secott, T.2    Isom, H.C.3
  • 56
    • 0030691207 scopus 로고    scopus 로고
    • Exposure of primary rat hepatocytes in long-term DMSO culture to selected transition metals induces hepatocyte proliferation and formation of duct-like structures
    • Cable EE, Isom HC: Exposure of primary rat hepatocytes in long-term DMSO culture to selected transition metals induces hepatocyte proliferation and formation of duct-like structures. Hepatology 1997, 26:1444-1457
    • (1997) Hepatology , vol.26 , pp. 1444-1457
    • Cable, E.E.1    Isom, H.C.2
  • 57
    • 0028895940 scopus 로고
    • Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release
    • Leist M, Gantner F, Jilg S, Wendel A: Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J Immunol 1995, 154:1307-1316
    • (1995) J Immunol , vol.154 , pp. 1307-1316
    • Leist, M.1    Gantner, F.2    Jilg, S.3    Wendel, A.4
  • 58
    • 0000742819 scopus 로고
    • Transforming growth factor β mRNA increases during liver regeneration: A possible paracrine mechanism of growth regulation
    • Braun L, Mead JE, Panzica M, Mikumo R, Bell GI, Fausto N: Transforming growth factor β mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation. Proc Natl Acad Sci USA 1988, 85:1539-1543
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1539-1543
    • Braun, L.1    Mead, J.E.2    Panzica, M.3    Mikumo, R.4    Bell, G.I.5    Fausto, N.6


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