Disruption of a receptor-mediated mechanism for intracellular sorting of proinsulin in familial hyperproinsulinemia

Molecular Endocrinology

Volumn 17, Issue 9, 2003, Pages 1856-1867

  Dhanvantari, Savita ^a,g   Shen, Fu Sheng ^a   Adams, Tiffany ^a   Snell, Christopher R ^b   Zhang, Chunfa ^a   Mackin, Robert B ^c   Morris, Stephen J ^d,f   Loh, Y Peng ^a,e  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b MEDIVIR AB   (Sweden)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f Aegera Therapeutics   (Canada)

^g LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE H; MUTANT PROTEIN; PROINSULIN; RECEPTOR PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOCRINE DISEASE; FAMILIAL DISEASE; GENE MUTATION; HORMONE BINDING; HORMONE BLOOD LEVEL; HORMONE STRUCTURE; HYPERPROINSULINEMIA; MOLECULAR MODEL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SECRETORY GRANULE; SITE DIRECTED MUTAGENESIS;

CARBOXYPEPTIDASE H; GENES, DOMINANT; HUMANS; HYDROGEN-ION CONCENTRATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROINSULIN; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; RNA INTERFERENCE;

ANIMALIA;

EID: 0042835761     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2002-0380     Document Type: Article

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