American cutaneous leishmaniasis, lepromatous leprosy, and pulmonary tuberculosis coinfection with downregulation of the T-helper 1 cell response

Clinical Infectious Diseases

Volumn 37, Issue 5, 2003, Pages 628-633

  Delobel, Pierre ^a   Launois, Pascal ^b   Djossou, Felix ^c,d   Sainte Marie, Dominique ^c,d   Pradinaud, Roger ^c,d  

^a CHU PURPAN   (France)

^b INSTITUT PASTEUR DE LA GUYANE   (French Guiana)

^c A Rosemon General Hospital   (French Guiana)

^d Inst Guyanais de Dermatol Trop   (French Guiana)

Author keywords

[No Author keywords available]

Indexed keywords

CLOFAZIMINE; DAPSONE; ETHAMBUTOL; ISONIAZID; PENTAMIDINE ISETHIONATE; PYRAZINAMIDE; RIFAMPICIN; THALIDOMIDE;

ADULT; ANTIMICROBIAL THERAPY; ARTICLE; CASE REPORT; CELLULAR IMMUNITY; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; DOWN REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LABORATORY TEST; LEISHMANIA; LEPROMATOUS LEPROSY; LUNG TUBERCULOSIS; MALE; MYCOBACTERIUM TUBERCULOSIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SKIN BIOPSY; SKIN EXAMINATION; SKIN LEISHMANIASIS; SUPERINFECTION; TH1 CELL; THORAX RADIOGRAPHY; TREATMENT OUTCOME; TREPONEMA PALLIDUM;

ADULT; ANIMALS; BRAZIL; DOWN-REGULATION; FRENCH GUIANA; HUMANS; LEISHMANIA GUYANENSIS; LEISHMANIASIS, CUTANEOUS; LEPROSY, LEPROMATOUS; MALE; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS; RADIOGRAPHY, THORACIC; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-12; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TUBERCULOSIS, PULMONARY;

EID: 0042832396     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/376632     Document Type: Article

References (16)

1. Jacobson RR, Krahenbuhl JL. Leprosy. Lancet 1999; 353:655-60.
2. Herwaldt BL. Leishmaniasis. Lancet 1999; 354:1191-9.
3. Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 2002; 20:581-620.
4. Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996; 383:787-93.
5. Mosmann TR, Coffmann RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7:145-73.
6. Presky DH, Yang H, Minetti LJ, et al. A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci USA 1996; 93:14002-7.
7. Rogge L, Papi A, Presky DH, et al. Antibodies to the IL-12 receptor beta 2 chain mark human Th1 but not Th2 cells in vitro and in vivo. J Immunol 1999; 162:3926-32.
8. Szabo SI, Dighe AS, Gubler U, Murphy KM. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 1997; 185:817-24.
9. + T cells unresponsive to IL-12. J Infect Dis 2001; 183:953-9.
10. -. Eur J Immunol 1995; 25:3298-307.
11. Shire D, Legroux P. Gene expression analysis using quantitative reverse transcription-polymerase chain reaction and a multispecific internal control. Methods Mol Biol 2000; 137:59-73.
12. Ottentof THM, Verreck FAW, Lichtenauer-Kaligis EGR, et al. Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae. Nat Genet 2002; 32:97-105.
13. Govoni G, Gros P. Macrophage NRAMP1 and its role in resistance to microbial infections. Inflamm Res 1998; 47:277-84.
14. Zhang M, Gong J, Presky DH, et al. Expression of the IL-12 receptor β1 and β2 subunits in human tuberculosis. J Immunol 1999; 162:2441-7.
15. Kim J, Uyemura K, Van Dyke MK, et al. A role for IL-12 receptor expression and signal transduction in host defense in leprosy. J Immunol 2001; 167:779-89.
16. Bourreau E, Prévot G, Pradinaud R, Launois P. Unresponsiveness of specific T cells to IL-12 is associated with active cutaneous leishmaniasis owing to Leishmania guyanensis. Scand J Immunol 2001; 54:335-9.